These thyroid function tests were obtained on a 55-year-old female who has recently been treated for hypertension:
Free T4 28.5 pmol/L (9.8-23.1)
TSH <0.02 mU/L (0.35-5.5)
Free T3 10.8 pmol/L (3.5-6.5)
She now presents with typical symptoms of hyperthyroidism.
Which medication is likely to have caused this?
A 55-year-old man with a smoking history of over 30 years presented to the emergency department with acute confusion and disorientation. He was unable to recognize his family members and relatives. He had been experiencing unexplained weight loss, loss of appetite, and occasional episodes of haemoptysis for the past few months. Urgent blood tests were performed, revealing abnormal levels of electrolytes and renal function.
Based on the likely diagnosis, what is the mechanism of action of the hormone that is being secreted excessively in this case?
What is the association between brown tumours of bone and a specific condition or disease?
You are in charge of the care of a 23-year-old man who has come for a military medical evaluation. Based on his symptoms, you suspect that he has type 1 diabetes and has been secretly administering insulin. What clinical methods can you use to evaluate his endogenous insulin production?
A 50-year-old woman has just had a thyroidectomy to treat medullary thyroid cancer. What is the clinical tumor marker used to screen for recurrence?
A 38-year-old woman is diagnosed with hyperthyroidism and started on carbimazole. What is the mechanism of action of this medication?
A 38-year-old woman visits her GP after being prescribed carbimazole for Grave’s disease. The GP must inform her of crucial side effects that require immediate medical attention if they occur. What is the most significant side effect?
A 60-year-old woman complains of persistent diarrhoea, wheezing, and flushing. During the physical examination, an irregular pulsatile hepatomegaly and a pansystolic murmur that is most pronounced during inspiration are detected. What diagnostic test could provide insight into the probable underlying condition?
A 55-year-old male visits his GP for an insurance medical. The GP observes that the patient has rough facial features, an enlarged tongue, and greasy skin. The patient is also experiencing profuse sweating. Which hormone excess is likely to be accountable for these symptoms?
A 34-year-old male presents with tingling in his thumb, index, and middle finger, along with complaints of excessive fatigue and snoring. Upon examination, he displays a prominent brow ridge and significant facial changes over time. Following blood tests and an MRI scan, the patient is prescribed octreotide. What is the mechanism of action of this medication?