MSFinals-1504

A 32-year-old man presents at the outpatient clinic with altered bowel habit and occasional per rectum bleeding for the past 3 months. During examination, he experiences tenderness on the left iliac fossa and is unable to tolerate a pr examination. His liver function tests at the general practice surgery showed an elevated alkaline phosphatase (ALP) level. Based on these symptoms, which of the following autoantibody screen findings is most likely?