MSFinals-5037

A patient arrives at the hospital reporting he took a significant overdose of paracetamol over 12 hours ago.

On exam, he appears unwell and has significant right upper quadrant tenderness and so acetylcysteine treatment was commenced.

An arterial blood gas with other specific tests taken 48 hours post first ingestion shows:

pH 7.20 7.35–7.45

pC02 5.0 kPa 4.4–5.9

pO2 11.0 kPa 10.0–14.0

HCO3 10 mmol/L 22–28

Lac 6 mmol/L <2 Creatinine 700 μmol/L 53–106 Bilirubin 400 μmol/L 2–17 Prothrombin time (PT) 20 sec 11-15 What result indicates that this case meets the King’s College Hospital criteria for liver transplantation?