MSFinals-5233

MSFinals-5233

A new medication is being tested on healthy participants. It is only distributed in the vascular space and has limited hepatic metabolism. At 10:00 am, an intramuscular injection of the medication is administered, and a peak plasma concentration is achieved by 11:00 am. The drug concentrations in the blood plasma at different time points are provided below:

Time Drug concentration
11:00 70 mg/L
13:00 50 mg/L
15:00 30 mg/L
17:00 10 mg/L
19:00 0.1 mg/L

What conclusion can be drawn about the clearance of this medication?