MSFinals-5693
A 56-year-old teacher presents to the Emergency Department with nausea and vomiting, with associated lethargy. She has mild asthma which is well controlled with a steroid inhaler but has no other medical history of note. She does not smoke but drinks up to 20 units of alcohol a week, mostly on the weekends. Observations are as follows:
Temperature is 37.2 oC, blood pressure is 110/70 mmHg, heart rate is 90 bpm and regular.
On examination, the patient appears to be clinically dehydrated, but there are no other abnormalities noted.
Blood tests reveal:
Investigation Result Normal Values
Haemoglobin (Hb) 140 g/l 135–175 g/l
White cell count (WCC) 7.8 × 109/l 4–11 × 109/l
Urea 8.5 mmol/l 2.5–6.5 mmol/l
Creatinine 190 µmol/l
(bloods carried out one year
previously showed a creatinine
of 80) 50–120 µmol/l
Potassium (K+) 4.7 mmol/l 3.5–5.0 mmol/l
Sodium (Na+) 133 mmol/l 135–145 mmol/l
Which of the following is most suggestive of acute kidney injury rather than chronic renal failure?