MSFinals-5106
A 65-year-old male patient visits an outpatient cardiology clinic for follow-up. He has a medical history of heart failure, type-2 diabetes, and osteoporosis. For the past 3 years, he has been taking NovoRapid (rapid-acting insulin analogue) 10iU three times daily, Lantus (insulin glargine) 3 iU once daily, ramipril 10 mg once daily, bisoprolol 5mg once daily, and AdCal D3 (calcium and vitamin D) two tablets once daily without any adverse effects. Recently, he was prescribed amiloride 10 mg once daily. His blood work reveals:
Na+ 141 mmol/L (135 – 145)
K+ 6.0 mmol/L (3.5 – 5.0)
Bicarbonate 28 mmol/L (22 – 29)
Urea 6.3 mmol/L (2.0 – 7.0)
Creatinine 92 µmol/L (55 – 120)
Which of his medications could have interacted with the new prescription to cause the abnormal blood results?