MSFinals-4920
What is the term used to describe the distribution of a drug throughout the body’s compartments?
Archives: Medical Student Finals
MSFinals-4921
A 50-year-old man is referred to the acute medical unit. He had presented earlier in the day to the GP complaining of ongoing fatigue and polydipsia. A BM (finger-prick glucose) taken in the surgery was 22.3 mmol/l. On examination he is an obese man (BMI 36 kg/m2) with a pulse of 84 bpm and blood pressure of 144/84 mmHg. Blood tests reveal the following:
Na+ 140 mmol/l
K+ 3.9 mmol/l
Bicarbonate 23 mmol/l
Urea 5.2 mmol/l
Creatinine 101 µmol/l
Glucose 18.2 mmol/l
You advise him to lose weight and discuss basic dietary advice. What is the most appropriate initial management?
MSFinals-4922
You are requested to assess a 75-year-old woman admitted to the surgical ward with complaints of unilateral leg swelling and shortness of breath. Upon examination, her heart rate is 98 beats per minute, and breath sounds are normal. The patient underwent a total hip replacement surgery a week ago, which was uneventful, and she was prescribed a 10-day course of unfractionated heparin post-surgery. Her blood tests reveal Hb levels of 138 g/L (Female: 115-160 g/L), platelet count of 120 * 109/L (150-400 * 109/L), and WBC count of 7.4 * 109/L (4.0-11.0 * 109/L). An ELISA test is conducted, which comes back positive for platelet factor 4. Based on the given information, what is the most probable cause of the patient’s symptoms?
MSFinals-4923
Low molecular weight heparin has the most significant inhibitory impact on which of the following proteins involved in the coagulation cascade?
MSFinals-4924
A 22-year-old woman is being evaluated in the Gastroenterology Clinic after being hospitalized for a Crohn’s flare. The physician is considering starting her on azathioprine to maintain remission while she is on steroids. What tests can be done to determine if azathioprine is suitable for this patient?
MSFinals-4925
A 61-year-old man has been experiencing stiffness in both hands, wrists and ankles for over a year. After undergoing serological testing and radiological imaging, he was diagnosed with rheumatoid arthritis. His rheumatologist has decided to start him on methotrexate therapy. He has a medical history that includes gout, chronic obstructive pulmonary disease (COPD), diabetes, and stage 2 chronic kidney disease.
What should be done before beginning methotrexate treatment?
MSFinals-4901
A 28-year-old construction worker is brought to the emergency department after being found unconscious at his worksite by his colleagues. He was found with an empty bottle of an unknown substance. There is no past medical history of note and he takes no regular medications.
Upon examination, he is disoriented and restless with a GCS of 10. His eyes and nose are watering and there is dried vomitus around his mouth. There is reduced air entry bilaterally with a respiratory rate of 8 breaths/min and there is evidence of muscle fasciculations.
Based on the probable diagnosis, which of the following examination findings is most likely to be present?
MSFinals-4902
What is a correct statement about a clinical drug trial that is double blind?
MSFinals-4903
Each of the following are true regarding tricyclic overdose in elderly patients, except:
MSFinals-4904
A 28-year-old woman with known depression is brought in to the Emergency Department with tachycardia, hypotension and decreased salivation. Her current prescribed medications include tricyclic antidepressants. Her partner thinks she may have taken a large amount of her tablets earlier on in the day following an argument.
Which of the following would be the most appropriate initial investigation?