A 50-year-old man is scheduled for a routine tooth extraction with his dentist. He has a history of type 2 diabetes and depression, but is otherwise in good health. His daily medications include metformin 850 mg three times a day, glimepiride 1 mg once a day, ramipril 5 mg once a day, isocarboxazid 20 mg once a day, and aspirin 75 mg once a day. Which medication should the dentist be informed about as a priority?
A 50-year old woman visits her General Practitioner (GP) for a cardiovascular risk assessment. She is worried about her family history of premature ischaemic heart disease, although she currently feels healthy. She has a history of hypertension that is well managed with bendroflumethiazide, amlodipine, and lisinopril. She has never smoked and only drinks on special occasions.
During the examination, her BMI is 30, heart rate is regular at 80 beats per minute, and blood pressure is 128/86 mmHg. The GP determines that the patient is at an increased risk of developing heart disease and wants to prescribe an additional medication to her current regimen.
What other medication should the GP consider for this patient?
A 29-year-old man presents to the Emergency Department after taking an overdose 48 hours ago following an argument with his girlfriend. He was intoxicated at the time and cannot recall what he ingested. Recently, his General Practitioner had prescribed him antidepressants. Laboratory tests reveal abnormal results, including elevated liver enzymes and prolonged prothrombin time. Based on these findings, which medication is the most probable cause of his overdose?
A group of nursing students attend a pharmacology lecture regarding the mechanisms of actions of certain medications.
Which one of the following drugs is correctly paired with the enzyme that it inhibits?
What is the most suitable time to collect blood samples for therapeutic monitoring of digoxin levels in elderly patients?
A 55-year-old male presents with persistent hypertension, with a blood pressure consistently above 170/100 mmHg. He has a history of asthma and is currently being treated with PRN salbutamol and Seretide. Which of the following antihypertensive medications should be avoided due to contraindications?
A 72-year-old woman is visited by her general practitioner and found to be suffering from constipation. This began after she was started on a new medication. She suffers from ischaemic heart disease, osteoarthritis, atrial fibrillation and moderate depression.
Which drug is most likely to have resulted in this woman’s symptoms?
A 30-year-old African man with a history of sickle cell anaemia has been admitted to the Respiratory Ward after presenting with a non-productive cough and pleuritic chest pain for the past two days. He has previously been hospitalized for pain crises and priapism. What medication is known to cause priapism?
What is the most suitable mechanism to describe the function of ezetimibe?
You are conducting a medication review for a 67-year-old man who has a medical history of cerebrovascular disease (having suffered a stroke 3 years ago), depression, and knee osteoarthritis. He is currently taking the following medications:
– Clopidogrel 75 mg once daily
– Simvastatin 20 mg once daily
– Amlodipine 5mg once daily
– Ramipril 10 mg once daily
– Diclofenac 50 mg as needed
– Sertraline 50 mg once daily
– Lansoprazole 15 mg once daily
What modification would be most appropriate for his medication regimen?