Archives: Medical Student Finals

MSFinals-3680

A 72-year-old man with advanced prostate cancer is referred by his GP to hospital as today’s blood test shows an elevated calcium level.
Which of the following is the next most appropriate action?

MSFinals-3681

A 67-year-old man has been diagnosed with transitional cell carcinoma of the bladder after presenting with haematuria. Are there any recognised occupational exposures that increase the risk of developing bladder cancer?

MSFinals-3682

A woman aged 57 presents with a unilateral ovarian mass, accompanied by a large omental metastasis.
Which of the following postoperative treatments is the most appropriate?

MSFinals-3683

A woman in her 40s has the BRCA2 mutation. What cancers are she and her family members at higher risk of developing?

MSFinals-3685

A pre-med student is preparing for her oncology rotation and is studying the use of tumour markers in the diagnosis and monitoring of cancer.
Which of the following tumour markers is accurately matched with the cancer it is linked to?

MSFinals-3686

A 51-year-old woman presents with a 5-month history of abdominal discomfort and bloating. She reports feeling fatigued and has lost around 5 kg in weight during this time. An ultrasound scan of the abdomen and pelvis reveals a solid mass with multiple compartments and high vascularity originating from the left ovary. Which tumour marker is expected to be elevated in this patient?

MSFinals-3687

A patient with rectal cancer in their 60s is seen by the colorectal nurse specialist and is told about a special blood test to monitor their disease.
Which of the following is this most likely to relate to?

MSFinals-3688

A 56-year-old man presents to his general practitioner with proximal muscle weakness. He has noticed difficulty in trying to get up out of a chair. There is a past history of obstructive airways disease and a 35-pack-year cigarette history. On examination, you notice that he has marked weakness of the pelvic and shoulder girdle and decreased tendon reflexes.
Investigations:
Investigation Result Normal value
sodium (Na+) 137 mmol/l 135–145 mmol/l
Potassium (K+) 4.5 mmol/l 3.5–5.0 mmol/l
Creatinine 95 μmol/l 50–120 µmol/l
Haemoglobin 115 g/l 135–175 g/l
White cell count (WCC) 6.2 × 109/l 4–11 × 109/l
Platelets 320 × 109/l 150–400 × 109/l
Erythrocyte sedimentation rate (ESR) 80 mm/hr 0–10mm in the 1st hour
You suspect that he may have an underlying malignancy with a paraneoplastic syndrome. Which of the following is most likely to be associated with this clinical picture?

MSFinals-3689

A 47-year-old woman with primary sclerosing cholangitis presents with a 2 week history of pain under her right rib cage and 2 days history of yellow skin and pale stools. She has also experienced a weight loss of 2 stone over the last 6 months. What would be the appropriate tumour marker investigation for this likely diagnosis?