A 47-year-old woman visits her doctor with a complaint of experiencing cold hands and feet over the last two weeks. Her medications have been recently altered, with a new medication introduced to improve her blood pressure management. Which of the following medications is the probable cause of her symptoms?
A 58-year-old male with a past of chronic alcohol abuse comes in with a two-day history of worsening confusion. During the examination, he appears drowsy, has a temperature of 39°C, a pulse of 110 beats per minute, and a small amount of ascites. The CNS examination reveals a left-sided hemiparesis with an upward left plantar response. What is the probable diagnosis?
A 57-year-old man has been experiencing itchy skin, particularly after bathing, and headaches. He has been diagnosed with a condition that requires regular venesection and medical therapy to reduce his risk of clots. Assuming he has received lifestyle advice, what is the appropriate medical management for him?
What is the process by which inhibitory postsynaptic potentials (IPSPs) work?
A healthcare assistant in her mid-30s presents to her general practitioner (GP) for a routine check-up. She reports a needlestick injury at work that occurred over a month ago, but she did not report it to occupational health as she believed the patient was low risk. She is now concerned about her infection status. The GP orders viral serology tests, which reveal the following results:
HIV PCR: Negative
Hepatitis C antibody: Negative
Hepatitis B surface antigen (HBsAg): Negative
Immunoglobulin M (IgM) anti-hepatitis B core (HBc) antigen: Negative
Anti-HBc (hepatitis B core antigen): Negative
Anti-HBs (hepatitis B surface antibody): Positive
Based on these results, what is the healthcare assistant’s hepatitis status?
A 30-year-old pregnant woman comes to the clinic with a new fever and a pruritic rash on her trunk and limbs. The rash is mainly macular and has a reticular pattern. She also reports experiencing pain in her knees, elbows, and wrists, with slight swelling in her left wrist. What is the probable infectious agent responsible for her symptoms?
A 77-year-old man who resides in a nursing home has been treated with co-amoxiclav for a chest infection. After completing the antibiotic course, he experiences abdominal pain, watery diarrhoea, and a temperature of 39.2°C. All other residents in the home are healthy. A stool sample is sent for testing as pseudomembranous colitis is suspected. What is the probable organism responsible for this condition?
A 25-year-old sexually active man comes to the clinic complaining of a rash that has been present all over his body for the past two weeks. He also reports having a painless sore on his penis a few weeks prior to the onset of the rash. Upon examination, a maculopapular rash is observed on his entire body, including the palms of his hands and soles of his feet. However, his penis appears normal. What is the most probable diagnosis?
A teenage girl is brought to you by her concerned mother. The girl has an erythematosus rash on her cheeks but is feeling fine otherwise. Upon examination, she has a ‘slapped cheek’ appearance.
What is the most probable organism responsible for this?
A 27-year-old male patient complains of fever, malaise, myalgia, and diarrhea that have been present for a week. Upon further inquiry, he reveals that he had unprotected sexual intercourse with multiple local women during his holiday in Thailand six weeks ago. The patient has no significant medical history except for receiving travel vaccinations and prophylactic medications. He has not visited his GP for several years. What tests would you conduct to confirm the diagnosis?