A 72-year-old pet shop owner comes in with a persistent cough and difficulty breathing during physical activity. A chest CT scan reveals a ground-glass appearance. What is the most frequently linked mechanism responsible for this reaction?
A 36-year-old HIV positive woman has been experiencing occasional headaches for the past 6 months but has not received any treatment. Recently, she started vomiting frequently and developed diplopia and a stiff neck. She was taken to the accident and emergency department for treatment. What are the possible treatment options for this woman?
A 4-year-old child is brought to the General Practice by his mother. She informs you that her son has had a fever and has not been as active during play sessions. She decided to bring him into the surgery when he erupted in a rash two days ago. On examination, he has a vesicular rash which is widely disseminated and intensely pruritic. He has a temperature of 38 °C. You diagnose him with a common childhood infection. The next day, a patient, who is 14 weeks’ pregnant, reports that she briefly baby sat for the child before she knew about his infection. She has no recollection of having the infection as a child and she is well in herself.
Given that the patient has been exposed to the infected child, what is the next best step in her management?
What is a true statement about Koplik’s spots?
What is true regarding the production of pooled plasma derivatives?
A 70-year-old man is referred to the medical team on call. He has been feeling fatigued for two months and is now experiencing shortness of breath with minimal exertion. He has also had several episodes of syncope with postural hypotension. The GP conducted a blood count and the results showed:
– Haemoglobin 64 g/L (120-160)
– MCV 62 fL (80-96)
– WCC 11.6 ×109L (4-11)
– Platelets 170 ×109L (150-400)
– MCH 22 pg (28-32)
What is the most appropriate next step?
A 72-year-old man is receiving a 2 units of blood transfusion for anaemia of unknown cause – haemoglobin (Hb) 65 g/l (normal 135–175 g/l). During the third hour of the blood transfusion he spikes a temperature of 38.1°C (normal 36.1–37.2°C). Otherwise the patient is asymptomatic and his other observations are normal.
Given the likely diagnosis, what should you do?
A woman has some blood tests taken by her general practitioner (GP). The results show a Hb of 10.0, MCV of 69 and a ferritin of 9.
Which is the most appropriate management plan for this patient?
A diabetic patient with idiopathic thrombocytopenic purpura presents with a leg ulcer which needs debridement. His platelet counts are 15 ×109/l. His blood sugars are poorly controlled and he has been started on a sliding scale insulin. He has previously responded to steroids and immunoglobulin infusions.
What is the recommended product to increase platelet counts to a safe level for debridement surgery in a diabetic patient with idiopathic thrombocytopenic purpura who has previously responded to steroids and immunoglobulin infusions and has poorly controlled blood sugars, and is slightly older?
A 70-year-old man presents with melaena and an INR of 8. He is currently taking warfarin for atrial fibrillation, as well as antihypertensive medication and cholesterol-lowering agents. He recently received antibiotics from his GP for a cough. Which medication is the likely culprit for his elevated INR?