MSFinals-1133

A 55-year-old male patient has been diagnosed with acromegaly. What is the most suitable treatment option for him?

MSFinals-1134

What is the accurate description of growth hormone (GH) and its role in normal growth?

MSFinals-1136

A 32-year-old woman visits her GP after experiencing sudden hair growth, specifically on her face. She is feeling increasingly self-conscious about it and wants to address the issue. Blood tests were conducted, revealing an elevated testosterone level of 9.8 nmol/l (reference range 0.8-3.1 nmol/l). What is the next course of action in managing her condition?

MSFinals-1104

A 60-year-old man with a 10-year history of type 2 diabetes comes in for his annual check-up. He is currently taking ramipril, pioglitazone, metformin, simvastatin, and acarbose. During previous examinations, he has been found to have microalbuminuria and a decreasing eGFR. His most recent eGFR measurement was 29 ml/minute/1.73 m2. He has an average build and height.

Which medication should be discontinued?

MSFinals-1105

A 55-year-old woman is undergoing investigation by her GP for potential issues in her hypothalamic-pituitary-thyroid axis. The following findings were recorded:
Thyroid-stimulating hormone (TSH) 5.2 mu/l (0.4-4.0 mu/l)
fT4 8.0 pmol/l (9.0-26.0 pmol/l)
fT3 3.5 pmol/l (3.0-9.0 pmol/l)
What condition is indicated by these results?

MSFinals-1106

A 30-year-old female with a two year history of type 1 diabetes presents with a two day history of colicky abdominal pain and vomiting. She has been relatively anorexic and has cut down on her insulin today as she has not been able to eat that much.

On examination she has a sweet smell to her breath, has some loss of skin turgor, has a pulse of 102 bpm regular and a blood pressure of 112/70 mmHg. Her abdomen is generally soft with some epigastric tenderness.

BM stix analysis reveals a glucose of 19 mmol/L (3.0-6.0).

What investigation would be the most important for this woman?

MSFinals-1107

Which test can be used to distinguish between insulinoma and exogenous insulin administration in a patient experiencing hypoglycaemia?

MSFinals-1108

A 52-year-old woman presents with complaints of irregular periods, weight loss, and excessive sweating. She reports that her symptoms have been gradually worsening over the past few months and she also experiences itching. During the examination, her blood pressure is measured at 140/80 mmHg and her resting pulse is 95 bpm.
What is the most suitable test to perform for this patient?

MSFinals-1109

What is the probable diagnosis for a 15-year-old girl who experiences recurring pelvic pain but has not yet begun menstruating?