MSFinals-0303
A 70-year-old woman was recently diagnosed with essential hypertension and started on a medication to lower her blood pressure. She then stopped taking the medication as she reported ankle swelling. Her blood pressure readings usually run at 160/110 mmHg. She denies any headache, palpitation, chest pain, leg claudication or visual problems. She was diagnosed with osteoporosis with occasional back pain and has been admitted to the hospital for a hip fracture on two occasions over the last 3 years. There is no history of diabetes mellitus, coronary artery disease or stroke. She has no known drug allergy. Her vital signs are within normal limits, other than high blood pressure. The S1 is loud. The S2 is normal. There is an S4 sound without a murmur, rub or gallop. The peripheral pulses are normal and symmetric. The serum electrolytes (sodium, potassium, calcium and chloride), creatinine and urea nitrogen are within normal range.
What is the most appropriate antihypertensive medication for this patient?