A 35-year-old man presents with complaints of frequent headaches. He also admits to experiencing erectile dysfunction and decreased sex drive that has progressively worsened over the past six months. Visual field examination reveals a bitemporal hemianopia. Laboratory examination reveals an elevation in serum prolactin, while serum luteinizing hormone (LH) and testosterone are decreased.
What is the most probable diagnosis?
A 38-year-old woman visits her GP with complaints of weight gain and irregular menstrual cycles. She reports feeling weak and depressed. During the examination, the doctor notices multiple purplish striae on her abdomen and bruises on her lower extremities. Laboratory tests show normal thyroid hormone levels and TSH, but elevated cortisol secretion. If the patient has adrenal hyperfunction, what other symptom may also be present?
A 21-year-old female medical student, who is an insulin-dependent diabetic, went on a weekend trip to visit some friends at another university. She forgot to pack her insulin.
When she returned, she went to visit her General Practitioner.
Which of the following blood results would be expected?
A 32-year-old man visits his doctor because he has been experiencing sweaty palms and his colleagues have noticed a change in his facial appearance. He also reports difficulty driving due to difficulty seeing the sides of his visual fields.
What is the most probable diagnosis?
A 42-year-old woman visits her GP with concerns of feeling constantly overheated and experiencing early menopause. Her husband has also noticed a swelling in her neck over the past few weeks. During the examination, her pulse is recorded at 90/minute, and a small, painless goitre is observed. The doctor orders blood tests, which reveal the following results: TSH < 0.05 mu/l, Free T4 24 pmol/l, Anti-thyroid peroxidase antibodies 102 IU/mL (< 35 IU/mL), and ESR 23 mm/hr. What is the most probable diagnosis?
A 67-year-old woman has just been prescribed gliclazide for her T2DM. What is the mechanism of action of gliclazide?
A diabetic woman in her 50s presents with painful diabetic neuropathy in her feet. She has no other significant medical history. What is the recommended initial treatment to alleviate her pain?
A 21-year-old man visits his GP with complaints of increased thirst throughout the day and difficulty performing everyday tasks. He was recently treated for a UTI with ciprofloxacin. His father has a history of diabetes, but is unsure of the type. He drinks about 8 units of alcohol per week. Fasting plasma glucose is 17.1 mmol/L (3.9-5.6), ketone bodies are 0.4 mmol/L (< 0.6 mmol/L), and C-peptide level is 2.87 ng/mL (0.51-2.72). What is the most likely diagnosis based on the patient's presentation?
A 35-year-old woman presents with excessive sweating and weight loss. Her partner reports that she is constantly on edge and you notice a fine tremor during the consultation. A large, nontender goitre is also noted. Upon examination of her eyes, there is no evidence of exophthalmos. Her pulse rate is 96/min. The following results were obtained: Free T4 26 pmol/l, Free T3 12.2 pmol/l (3.0-7.5), and TSH < 0.05 mu/l. What is the most likely diagnosis?
A 55-year-old woman presents to a walk-in clinic with complaints of fatigue and feeling cold for the past two months. She has become increasingly distressed by these symptoms and reports a recent weight gain of approximately 5kg. Which of her regular medications could potentially be causing these symptoms?