A 55-year-old woman comes to the clinic with symptoms of petechiae, purpura, and epistaxis. She had a cold 6 weeks ago and has no known family history of bleeding disorders. Her lab results show a platelet count of 80 * 109/L (normal range: 150 – 400). What is the recommended first-line treatment for her likely diagnosis?
A 14-year-old girl is referred to haematology due to heavy and prolonged periods that have not responded well to tranexamic acid and the combined oral contraceptive pill. Her blood tests reveal Hb of 10.3 g/dl, Plt of 239 * 109/l, WBC of 6.5 * 109/l, PT of 12.9 secs, and APTT of 37 secs. What is the probable diagnosis?
Which of the following may be linked to a higher risk of venous thromboembolism?
Sophie, a 23-years old woman, visits her doctor complaining of frequent nosebleeds and unexplained bruising on her arms and legs. She mentions that her mother has also experienced similar issues but never sought medical attention. As a result, the doctor orders several blood tests to determine the most probable diagnosis.
What kind of results would be anticipated based on the likely diagnosis?
A 26-year-old woman presents with swelling and pain in one calf. Upon Doppler ultrasound scan, an unprovoked DVT is discovered. She expresses a strong desire to start a family with her partner within the next year. Which medication would be the most appropriate choice?
A 25-year-old woman comes to the clinic complaining of fatigue. Upon conducting blood tests, the following results are obtained:
– Hemoglobin (Hb): 10.4 g/dl
– Platelets (Plt): 278 * 109/l
– White blood cell count (WCC): 6.3 * 109/l
– Mean corpuscular volume (MCV): 65 fl
– Hemoglobin A2 (HbA2): 4.5% (< 3%)
What is the most probable diagnosis?
A 25-year-old male comes to the emergency department complaining of cough, fever and difficulty breathing. During the examination, he is found to be hypoxic and chest x-ray reveals pulmonary infiltrates. He has been experiencing anaemia, jaundice and weakness since he was 6 months old, and also suffers from severe pain when exposed to cold temperatures. What is the probable underlying condition?
A 42-year-old female presents to her primary care physician with a 2-month history of progressive fatigue. She has a medical history of type-1 diabetes mellitus. Her doctor orders a full blood count, which reveals a low Hb and high mean cell volume. The platelet and WBC counts are within normal limits. Which antibody test should be performed to assist in the diagnosis?
A 30-year-old female who is 36 weeks pregnant comes in with a painful and swollen right calf. After a Doppler scan, it is confirmed that she has a deep vein thrombosis. What anticoagulant is recommended?
A 65-year-old man with lung cancer is currently on MST 30 mg bd for pain management. What dosage of oral morphine solution should be prescribed for his breakthrough pain?