MSRA-0713

You are evaluating a patient with Crohn’s disease. Which of the following non-intestinal symptoms of Crohn’s disease is associated with disease activity?

MSRA-0714

A 25-year-old female presents with a history of weight loss and diarrhoea. To investigate her symptoms, she undergoes a colonoscopy and a biopsy is taken. The biopsy report indicates the presence of pigment-laden macrophages suggestive of melanosis coli. What is the probable diagnosis?

MSRA-0715

A 60-year-old woman has been diagnosed with Parkinson’s disease and is currently taking Sinemet (co-careldopa) prescribed by her neurologist. However, she is experiencing severe nausea as a side effect. What is the best anti-emetic medication to recommend?

MSRA-0716

A 16-year-old male is being evaluated for iron-deficiency anemia and is discovered to have multiple polyps in his jejunum. During the examination, pigmented lesions are observed on his palms and soles. What is the probable diagnosis?

MSRA-0717

What is the most commonly associated condition with primary sclerosing cholangitis?

MSRA-0718

A 25-year-old man presents with a two week history of diarrhoea. He reports that his bowel movements have not been normal for the past few months and he frequently experiences urgency to use the toilet. However, these symptoms had been improving until two weeks ago. He has also noticed blood in his stool for the past week and feels like he hasn’t fully emptied his bowels after going. Despite these symptoms, he has not experienced any weight loss and has a good appetite. On examination, there is mild tenderness in the left lower quadrant of his abdomen but no guarding. What is the most likely diagnosis?

MSRA-0719

A 32-year-old female with a history of alcoholic liver disease presents with frank haematemesis. She had been discharged just two months ago after receiving treatment for bleeding oesophageal varices. What is the most suitable course of action to take while waiting for endoscopy after resuscitation?

MSRA-0720

A 65-year-old man presents to your clinic with a chief complaint of progressive difficulty in swallowing over the past 4 months. Upon further inquiry, he reports a weight loss of approximately 2.5 kilograms, which he attributes to a decreased appetite. He denies any pain with swallowing or regurgitation of food. During the interview, you observe a change in his voice quality. What is the probable diagnosis?

MSRA-0721

A 45-year-old man with type 2 diabetes mellitus presents with fatigue. He is currently taking metformin and gliclazide, but may need to discontinue the latter due to his obesity. After conducting several blood tests, the following results were obtained:
– HbA1c: 66 mmol/mol (< 48)
– Ferritin: 204 ng/mL (25 – 350)
– Bilirubin: 23 µmol/L (3 – 17)
– ALP: 162 u/L (30 – 100)
– ALT: 120 u/L (3 – 40)
– AST: 109 u/L (3 – 40)

Upon further discussion, the patient denies consuming alcohol. What is the most likely explanation for these abnormal findings?

MSRA-0722

A 30-year-old female who is being investigated for secondary amenorrhoea comes in with yellowing of the eyes. During the examination, spider naevi are observed, and the liver is tender and enlarged. The blood tests reveal the following results: Hb 11.6 g/dl, Plt 145 * 109/l, WCC 6.4 * 109/l, Albumin 33 g/l, Bilirubin 78 µmol/l, and ALT 245 iu/l. What is the most probable diagnosis?