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  • Question 1 - A 55-year-old woman visits her GP clinic for a routine cervical smear. After...

    Correct

    • A 55-year-old woman visits her GP clinic for a routine cervical smear. After receiving an initial high-risk human papillomavirus (hrHPV) result, she is scheduled for a follow-up smear in 12 months. During the subsequent smear, she is informed that the hrHPV result is now negative. She has no significant medical history. What is the best course of action for her management?

      Your Answer: Repeat smear in 5 years

      Explanation:

      The correct course of action for a patient who had a positive high-risk human papillomavirus (hrHPV) but negative cytology result in their initial smear and a negative hrHPV result in their subsequent 12-month repeat smear is to return to routine recall. This means that the patient should have their next smear in 5 years, as they are in the appropriate age group for this interval. Referring the patient for colposcopy is not necessary in this case, as the cytology result was negative. Repeating the smear in 3 months is also not necessary, as this is only done for inadequate samples. If the hrHPV result is positive again in a further 12-month repeat, then repeating the smear in another 12 months would be appropriate. However, if the hrHPV result is negative in the second repeat, the patient can be returned to routine recall. For younger patients, the appropriate interval for routine recall is 3 years.

      The cervical cancer screening program has evolved to include HPV testing, which allows for further risk stratification. A negative hrHPV result means a return to normal recall, while a positive result requires cytological examination. Abnormal cytology results lead to colposcopy, while normal cytology results require a repeat test at 12 months. Inadequate samples require a repeat within 3 months, and two consecutive inadequate samples lead to colposcopy. Treatment for CIN typically involves LLETZ or cryotherapy. Individuals who have been treated for CIN should be invited for a test of cure repeat cervical sample 6 months after treatment.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 2 - A 60-year-old patient who has not undergone a hysterectomy visits her GP clinic...

    Correct

    • A 60-year-old patient who has not undergone a hysterectomy visits her GP clinic for a follow-up on her hormone replacement therapy (HRT). She is currently using an estradiol patch that she changes once a week and taking norethisterone orally on a daily basis.

      What is the primary advice that the patient should be mindful of when taking progestogens?

      Your Answer: Increased risk of breast cancer

      Explanation:

      The addition of progesterone to hormone replacement therapy (HRT) has been linked to an increased risk of breast cancer, as well as venous thromboembolism and cardiovascular disease. HRT may be recommended for menopausal patients experiencing vasomotor symptoms such as hot flashes, night sweats, and palpitations. However, if a patient only presents with urogenital symptoms, topical oestrogens such as oestradiol creams or pessaries may be more appropriate. These act locally to alleviate vaginal dryness, reduce UTI recurrence, and ease dyspareunia. For patients with vasomotor symptoms, HRT preparations with systemic effects (such as oral medications, topical patches, and implants) may be considered. If the patient has not undergone a hysterectomy, their HRT regime must include both oestrogen and progesterone to prevent hypertrophy of the uterus and a 5-10x increased risk of endometrial carcinoma associated with unopposed oestrogen therapy.

      Adverse Effects of Hormone Replacement Therapy

      Hormone replacement therapy (HRT) is a treatment that involves the use of a small dose of oestrogen, often combined with a progesterone in women with a uterus, to alleviate menopausal symptoms. While it can be effective in reducing symptoms such as hot flashes and vaginal dryness, HRT can also have adverse effects and potential complications.

      Some common side-effects of HRT include nausea, breast tenderness, fluid retention, and weight gain. However, there are also more serious potential complications associated with HRT. For example, the use of HRT has been linked to an increased risk of breast cancer, particularly when a progesterone is added. The Women’s Health Initiative study found a relative risk of 1.26 at 5 years of developing breast cancer with HRT use. The risk of breast cancer is also related to the duration of use, and it begins to decline when HRT is stopped.

      Another potential complication of HRT is an increased risk of endometrial cancer. Oestrogen by itself should not be given as HRT to women with a womb, as this can increase the risk of endometrial cancer. The addition of a progesterone can reduce this risk, but it is not eliminated completely. The British National Formulary states that the additional risk is eliminated if a progesterone is given continuously.

      HRT has also been associated with an increased risk of venous thromboembolism (VTE), particularly when a progesterone is added. However, transdermal HRT does not appear to increase the risk of VTE. Women who are at high risk for VTE should be referred to haematology before starting any treatment, even transdermal, according to the National Institute for Health and Care Excellence (NICE).

      Finally, HRT has been linked to an increased risk of stroke and ischaemic heart disease if taken more than 10 years after menopause. It is important for women considering HRT to discuss the potential risks and benefits with their healthcare provider and make an informed decision based on their individual circumstances.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 3 - A 18-year-old woman presents to the specialist clinic for insertion of an intrauterine...

    Incorrect

    • A 18-year-old woman presents to the specialist clinic for insertion of an intrauterine system (IUS). During the procedure, the clinician observes scarring around the anterior genital area and an absent clitoris. Upon further discussion, the patient reveals that she underwent surgery during a family trip abroad about 8 years ago, but cannot recall the specifics. She expresses contentment with the situation and declines any further investigation or involvement of law enforcement. What should be the clinician's next course of action?

      Your Answer: Contact the medical director

      Correct Answer: Report the incident to the police

      Explanation:

      If an 18-year-old woman is suspected to be a victim of female genital mutilation (FGM), the best course of action is to report the incident to the police as FGM is illegal in the UK. Contacting the medical director or providing the patient with self-referral pathway information are not appropriate responses. It is important to acknowledge the patient’s wishes, but due to her age, reporting the incident to the police is necessary for investigation.

      Understanding Female Genital Mutilation

      Female genital mutilation (FGM) is a term used to describe any procedure that involves the partial or complete removal of the external female genitalia or any other injury to the female genital organs for non-medical reasons. The World Health Organization (WHO) has classified FGM into four types. Type 1 involves the partial or total removal of the clitoris and/or the prepuce, while type 2 involves the partial or total removal of the clitoris and the labia minora, with or without excision of the labia majora. Type 3 involves the narrowing of the vaginal orifice with the creation of a covering seal by cutting and appositioning the labia minora and/or the labia majora, with or without excision of the clitoris. Finally, type 4 includes all other harmful procedures to the female genitalia for non-medical purposes, such as pricking, piercing, incising, scraping, and cauterization. It is important to understand the different types of FGM to raise awareness and prevent this harmful practice.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 4 - A 32-year-old woman visits her GP seeking advice on contraception four weeks after...

    Correct

    • A 32-year-old woman visits her GP seeking advice on contraception four weeks after giving birth to her second child. She is currently breastfeeding and has a BMI of 27 kg/m^2. Her husband has a vasectomy scheduled in two months. What is the best contraceptive option for her?

      Your Answer: Progesterone only pill

      Explanation:

      After giving birth, women need to use contraception after 21 days. The progesterone-only pill (POP) can be started at any time postpartum, according to the FSRH. Additional contraception should be used for the first two days after day 21. A small amount of progesterone enters breast milk, but it is not harmful to the infant. On the other hand, the combined oral contraceptive pill (COCP) is absolutely contraindicated (UKMEC 4) if breastfeeding is less than six weeks post-partum. If breastfeeding is between six weeks and six months postpartum, it is a UKMEC 2. The COCP may reduce breast milk production in lactating mothers. It should not be used in the first 21 days due to the increased venous thromboembolism risk post-partum. After day 21, additional contraception should be used for the first seven days. The intrauterine device or intrauterine system can be inserted within 48 hours of childbirth or after four weeks.

      The lactational amenorrhoea method (LAM) is 98% effective if the woman is fully breastfeeding (no supplementary feeds), amenorrhoeic, and less than six months post-partum. It is important to note that an inter-pregnancy interval of less than 12 months between childbirth and conceiving again is associated with an increased risk of preterm birth, low birth weight, and small for gestational age babies.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 5 - A 55-year-old woman visits her GP for a routine smear test and is...

    Correct

    • A 55-year-old woman visits her GP for a routine smear test and is found to be HPV positive. A follow-up cytology swab reveals normal cells. She is asked to return for a second HPV swab after 12 months, which comes back negative. What is the next appropriate step in managing this patient?

      Your Answer: Repeat HPV test in 5 years

      Explanation:

      If the 2nd repeat smear at 24 months shows a negative result for high-risk human papillomavirus (hrHPV), the patient can return to routine recall for cervical cancer screening. Since the patient is over 50 years old, a smear test should be taken every 5 years as part of routine recall. It is not necessary to perform a cytology swab or refer the patient to colposcopy as a negative HPV result does not indicate the presence of cervical cancer. Additionally, repeating the HPV test in 3 years is not necessary for this patient as it is only the routine recall protocol for patients aged 25-49.

      The cervical cancer screening program has evolved to include HPV testing, which allows for further risk stratification. A negative hrHPV result means a return to normal recall, while a positive result requires cytological examination. Abnormal cytology results lead to colposcopy, while normal cytology results require a repeat test at 12 months. Inadequate samples require a repeat within 3 months, and two consecutive inadequate samples lead to colposcopy. Treatment for CIN typically involves LLETZ or cryotherapy. Individuals who have been treated for CIN should be invited for a test of cure repeat cervical sample 6 months after treatment.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 6 - A 56-year-old postmenopausal woman visits her GP complaining of increased urinary frequency and...

    Incorrect

    • A 56-year-old postmenopausal woman visits her GP complaining of increased urinary frequency and urgency for the past 4 days, along with two instances of urinary incontinence. She has a medical history of type 2 diabetes mellitus (managed with metformin) and diverticular disease. She does not smoke but admits to consuming one bottle of wine every night. During the examination, her heart rate is 106 bpm, and she experiences non-specific lower abdominal discomfort. Perineal sensation and anal tone are normal. What is the most probable cause of this patient's incontinence?

      Your Answer: Alcohol excess

      Correct Answer: Urinary tract infection

      Explanation:

      Causes and Precipitants of Urge Incontinence: A Brief Overview

      Urge incontinence, characterized by involuntary leakage of urine associated with or following urgency, is a common condition in women. It is caused by overactivity of the detrusor muscle in the bladder wall, leading to irregular contractions during the filling phase and subsequent leakage of urine. While there are many causes and precipitants of urge incontinence, it is often difficult to identify a single factor in the presence of multiple contributing factors.

      Some of the common causes of urge incontinence include poorly controlled diabetes, excess caffeine and alcohol intake, neurological dysfunction, urinary infection or faecal impaction, and adverse medication effects. In the case of a patient presenting with a short history of symptoms, urinary tract infection is the most likely cause, and prompt treatment is necessary to prevent complications.

      It is important to rule out developing cauda equina, a medical emergency that can lead to paralysis, in patients presenting with short-term urinary incontinence. Normal anal tone and perineal sensation can help exclude this condition.

      Excess alcohol and caffeine intake can precipitate symptoms of urge incontinence by inducing diuresis, causing frequency and polyuria. Chronic constipation, particularly in patients with diverticular disease, can also compress the bladder and lead to urge incontinence symptoms. Systemic illnesses such as diabetes mellitus can cause glycosuria and polyuria, leading to bladder irritation and detrusor instability. Finally, oestrogen deficiency associated with postmenopausal status can cause vaginitis and urethritis, both of which can precipitate urge incontinence symptoms.

      In conclusion, urge incontinence is a complex condition with multiple contributing factors. Identifying and addressing these factors can help manage symptoms and improve quality of life for affected patients.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 7 - A 62-year-old woman comes to the clinic with a complaint of postmenopausal bleeding...

    Correct

    • A 62-year-old woman comes to the clinic with a complaint of postmenopausal bleeding that has been going on for a month. She takes aspirin 75 mg once daily as her only medication. An ultrasound scan of the uterus reveals an endometrial lining thickness of 4.1 mm. Although an endometrial pipelle biopsy was performed, it was inconclusive. What should be the next course of action?

      Your Answer: Hysteroscopy with biopsy

      Explanation:

      Investigation is necessary for any postmenopausal bleeding. The first step is to conduct a transvaginal ultrasound scan to examine the thickness of the endometrium. To diagnose endometrial cancer, a Pipelle biopsy is used to sample the endometrium, which is effective in most cases. Hysteroscopy with directed sampling (dilation and curettage) can be used to detect lesions or when Pipelle has been inconclusive. CT scan is not required as a pre-operative imaging test nor is it used to diagnose endometrial cancer.
      Reference: Colombo N, Preti E, Landoni F, Carinelli S, Colombo A, et al. Endometrial cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013; 24 (6): vi33-vi38.

      Endometrial cancer is a type of cancer that is commonly found in women who have gone through menopause, but it can also occur in around 25% of cases before menopause. The prognosis for this type of cancer is usually good due to early detection. There are several risk factors associated with endometrial cancer, including obesity, nulliparity, early menarche, late menopause, unopposed estrogen, diabetes mellitus, tamoxifen, polycystic ovarian syndrome, and hereditary non-polyposis colorectal carcinoma. Postmenopausal bleeding is the most common symptom of endometrial cancer, which is usually slight and intermittent initially before becoming more heavy. Pain is not common and typically signifies extensive disease, while vaginal discharge is unusual.

      When investigating endometrial cancer, women who are 55 years or older and present with postmenopausal bleeding should be referred using the suspected cancer pathway. The first-line investigation is trans-vaginal ultrasound, which has a high negative predictive value for a normal endometrial thickness (< 4 mm). Hysteroscopy with endometrial biopsy is also commonly used for investigation. The management of localized disease involves total abdominal hysterectomy with bilateral salpingo-oophorectomy, while patients with high-risk disease may have postoperative radiotherapy. progesterone therapy is sometimes used in frail elderly women who are not considered suitable for surgery. It is important to note that the combined oral contraceptive pill and smoking are protective against endometrial cancer.

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      • Gynaecology
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  • Question 8 - A 30-year-old woman complains of dyspareunia and abnormal vaginal discharge that looks like...

    Incorrect

    • A 30-year-old woman complains of dyspareunia and abnormal vaginal discharge that looks like 'cottage cheese'. She is currently taking the combined oral contraceptive pill (COCP) and had her last period 5 days ago. What treatment should be recommended for the probable diagnosis?

      Your Answer: Clotrimazole intravaginal pessary

      Correct Answer: Oral fluconazole

      Explanation:

      For non-pregnant women with vaginal thrush, the recommended first-line treatment is a single-dose of oral fluconazole. This is based on NICE guidelines for the diagnosis of vaginal candidiasis. The use of clotrimazole intravaginal pessary is only recommended if the patient is unable to take oral treatment due to safety concerns. Oral nystatin is not appropriate for this condition as it is used for oral candidiasis. While topical clotrimazole can be used to treat vaginal candidiasis, it is not the preferred first-line treatment and should only be used if fluconazole is not effective or contraindicated.

      Vaginal candidiasis, also known as thrush, is a common condition that many women can diagnose and treat themselves. Candida albicans is responsible for about 80% of cases, while other candida species cause the remaining 20%. Although most women have no predisposing factors, certain factors such as diabetes mellitus, antibiotics, steroids, pregnancy, and HIV can increase the likelihood of developing vaginal candidiasis. Symptoms include non-offensive discharge resembling cottage cheese, vulvitis, itching, vulval erythema, fissuring, and satellite lesions. A high vaginal swab is not routinely indicated if the clinical features are consistent with candidiasis. Treatment options include local or oral therapy, with oral fluconazole 150 mg as a single dose being the first-line treatment according to NICE Clinical Knowledge Summaries. If there are vulval symptoms, a topical imidazole may be added to an oral or intravaginal antifungal. Pregnant women should only use local treatments. Recurrent vaginal candidiasis is defined as four or more episodes per year by BASHH. Compliance with previous treatment should be checked, and a high vaginal swab for microscopy and culture should be performed to confirm the diagnosis. A blood glucose test may be necessary to exclude diabetes, and differential diagnoses such as lichen sclerosus should be ruled out. An induction-maintenance regime involving oral fluconazole may be considered. Induction involves taking oral fluconazole every three days for three doses, while maintenance involves taking oral fluconazole weekly for six months.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 9 - A 27-year-old woman participates in the UK cervical screening programme and receives an...

    Correct

    • A 27-year-old woman participates in the UK cervical screening programme and receives an 'inadequate sample' result from her cervical smear test. After a repeat test 3 months later, she still receives an 'inadequate sample' result. What should be done next?

      Your Answer: Colposcopy

      Explanation:

      In the NHS cervical screening programme, cervical cancer screening involves testing for high-risk HPV (hrHPV) first. If the initial test results in an inadequate sample, it should be repeated after 3 months. If the second test also returns as inadequate, then colposcopy should be performed. This is because without obtaining hr HPV status or performing cytology, the risk of cervical cancer cannot be assessed. It would be unsafe to return the patient to normal recall as this could result in a delayed diagnosis of cervical cancer. Repeating the test after 3, 6 or 12 months is also not recommended as it may lead to a missed diagnosis.

      The cervical cancer screening program has evolved to include HPV testing, which allows for further risk stratification. A negative hr HPV result means a return to normal recall, while a positive result requires cytological examination. Abnormal cytology results lead to colposcopy, while normal cytology results require a repeat test at 12 months. Inadequate samples require a repeat within 3 months, and two consecutive inadequate samples lead to colposcopy. Treatment for CIN typically involves LLETZ or cryotherapy. Individuals who have been treated for CIN should be invited for a test of cure repeat cervical sample 6 months after treatment.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 10 - A 19-year-old female patient visits her doctor urgently seeking emergency contraception after having...

    Correct

    • A 19-year-old female patient visits her doctor urgently seeking emergency contraception after having unprotected sex 80 hours ago. She is currently on day 20 of her menstrual cycle. The doctor discovers that the patient was previously prescribed ellaOne (ulipristal acetate) for a similar situation just 10 days ago. What would be an appropriate emergency contraception method for this patient?

      Your Answer: ellaOne (ulipristal acetate) pill

      Explanation:

      Emergency contraception is available in the UK through two methods: emergency hormonal contraception and intrauterine device (IUD). Emergency hormonal contraception includes two types of pills: levonorgestrel and ulipristal. Levonorgestrel works by stopping ovulation and inhibiting implantation, while ulipristal primarily inhibits ovulation. Levonorgestrel should be taken as soon as possible after unprotected sexual intercourse, within 72 hours, and is 84% effective when used within this time frame. The dose should be doubled for those with a BMI over 26 or weight over 70kg. Ulipristal should be taken within 120 hours of intercourse and may reduce the effectiveness of hormonal contraception. The most effective method of emergency contraception is the copper IUD, which can be inserted within 5 days of unprotected intercourse or up to 5 days after the likely ovulation date. It may inhibit fertilization or implantation and is 99% effective regardless of where it is used in the cycle. Prophylactic antibiotics may be given if the patient is at high risk of sexually transmitted infection.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 11 - A 25-year-old woman presents with an ectopic pregnancy that has been confirmed by...

    Correct

    • A 25-year-old woman presents with an ectopic pregnancy that has been confirmed by ultrasound. However, the ultrasound report only mentions that the ectopic pregnancy is located in the 'left fallopian tube' without providing further details. To ensure appropriate management, you contact the ultrasound department to obtain more specific information. Which location of ectopic pregnancy is most commonly associated with a higher risk of rupture?

      Your Answer: Isthmus

      Explanation:

      The risk of rupture is higher in ectopic pregnancies that are located in the isthmus of the fallopian tube. This is because the isthmus is not as flexible as other locations and cannot expand to accommodate the growing embryo/fetus. It should be noted that ectopic pregnancies can occur in various locations, including the ovary, cervix, and even outside the reproductive organs in the peritoneum.

      Understanding Ectopic Pregnancy: The Pathophysiology

      Ectopic pregnancy is a medical condition where the fertilized egg implants outside the uterus, usually in the fallopian tube. According to statistics, 97% of ectopic pregnancies occur in the fallopian tube, with most of them happening in the ampulla. However, if the implantation occurs in the isthmus, it can be more dangerous. The remaining 3% of ectopic pregnancies can occur in the ovary, cervix, or peritoneum.

      During ectopic pregnancy, the trophoblast, which is the outer layer of the fertilized egg, invades the tubal wall, leading to bleeding that may dislodge the embryo. The natural history of ectopic pregnancy involves three possible outcomes: absorption, tubal abortion, or tubal rupture.

      Tubal abortion occurs when the embryo dies, and the body expels it along with the blood. On the other hand, tubal absorption occurs when the tube does not rupture, and the blood and embryo are either shed or converted into a tubal mole and absorbed. However, if the tube ruptures, it can lead to severe bleeding, shock, and even death.

      In conclusion, understanding the pathophysiology of ectopic pregnancy is crucial in diagnosing and managing this potentially life-threatening condition. Early detection and prompt treatment can help prevent complications and improve outcomes.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 12 - A 27-year-old female comes to the GP seeking advice on her contraceptive options....

    Incorrect

    • A 27-year-old female comes to the GP seeking advice on her contraceptive options. She has been relying on condoms but has recently entered a new relationship and wants to explore other methods. She expresses concern about the possibility of gaining weight from her chosen contraception.
      What should this woman avoid?

      Your Answer: Combined oral contraceptive pill

      Correct Answer: Injectable contraceptive

      Explanation:

      Depo-provera is linked to an increase in weight.

      If this woman is concerned about weight gain, it is best to avoid depo-provera, which is the primary injectable contraceptive in the UK. Depo-provera can cause various adverse effects, including weight gain, irregular bleeding, delayed return to fertility, and an increased risk of osteoporosis.

      While some users of the combined oral contraceptive pill have reported weight gain, a Cochrane review does not support a causal relationship. There are no reasons for this woman to avoid the combined oral contraceptive pill.

      The progesterone-only pill has not been associated with weight gain and is safe for use in this woman.

      The intra-uterine system (IUS) does not cause weight gain in users and is a viable option for this woman.

      The subdermal contraceptive implant can cause irregular or heavy bleeding, as well as progesterone-related side effects such as headaches, nausea, and breast pain. However, it is not typically associated with weight gain and is not contraindicated for use in this situation.

      Injectable Contraceptives: Depo Provera

      Injectable contraceptives are a popular form of birth control in the UK, with Depo Provera being the main option available. This contraceptive contains 150 mg of medroxyprogesterone acetate and is administered via intramuscular injection every 12 weeks. It can be given up to 14 weeks after the last dose without the need for extra precautions. The primary method of action is by inhibiting ovulation, while secondary effects include cervical mucous thickening and endometrial thinning.

      However, there are some disadvantages to using Depo Provera. Once the injection is given, it cannot be reversed, and there may be a delayed return to fertility of up to 12 months. Adverse effects may include irregular bleeding and weight gain, and there is a potential increased risk of osteoporosis. It should only be used in adolescents if no other method of contraception is suitable.

      It is important to note that there are contraindications to using Depo Provera, such as current breast cancer (UKMEC 4) or past breast cancer (UKMEC 3). While Noristerat is another injectable contraceptive licensed in the UK, it is rarely used in clinical practice and is given every 8 weeks. Overall, injectable contraceptives can be an effective form of birth control, but it is important to weigh the potential risks and benefits before deciding on this method.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 13 - A 22-year-old female patient comes to see her doctor, 2 weeks after undergoing...

    Incorrect

    • A 22-year-old female patient comes to see her doctor, 2 weeks after undergoing a medical abortion. She has concerns that the procedure may not have been successful as her home pregnancy test still shows a positive result. What is the expected timeframe for the pregnancy test to become negative if the abortion was effective?

      Your Answer:

      Correct Answer: Negative 2 weeks from today

      Explanation:

      After a termination of pregnancy, a urine pregnancy test can still show positive results for up to 4 weeks. If the test remains positive beyond this time frame, it may indicate an incomplete abortion or persistent trophoblast. In this case, the correct answer to when the pregnancy test should be negative is 2 weeks from now, as the termination occurred 2 weeks ago. A negative result one week ago is not relevant, and 4 weeks from today or 8 weeks from today are both incorrect as they fall outside of the 4-week window.

      Termination of Pregnancy in the UK

      The UK’s current abortion law is based on the 1967 Abortion Act, which was amended in 1990 to reduce the upper limit for termination from 28 weeks to 24 weeks gestation. To perform an abortion, two registered medical practitioners must sign a legal document, except in emergencies where only one is needed. The procedure must be carried out by a registered medical practitioner in an NHS hospital or licensed premise.

      The method used to terminate a pregnancy depends on the gestation period. For pregnancies less than nine weeks, mifepristone (an anti-progesterone) is administered, followed by prostaglandins 48 hours later to stimulate uterine contractions. For pregnancies less than 13 weeks, surgical dilation and suction of uterine contents is used. For pregnancies more than 15 weeks, surgical dilation and evacuation of uterine contents or late medical abortion (inducing ‘mini-labour’) is used.

      The 1967 Abortion Act outlines the circumstances under which a person shall not be guilty of an offence under the law relating to abortion. These include if two registered medical practitioners are of the opinion, formed in good faith, that the pregnancy has not exceeded its 24th week and that the continuance of the pregnancy would involve risk, greater than if the pregnancy were terminated, of injury to the physical or mental health of the pregnant woman or any existing children of her family. The limits do not apply in cases where it is necessary to save the life of the woman, there is evidence of extreme fetal abnormality, or there is a risk of serious physical or mental injury to the woman.

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      • Gynaecology
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  • Question 14 - A 55-year-old woman comes to the postmenopausal bleeding clinic complaining of light vaginal...

    Incorrect

    • A 55-year-old woman comes to the postmenopausal bleeding clinic complaining of light vaginal bleeding and mild discomfort during intercourse for the past two weeks. She reports feeling generally healthy. During a vaginal exam, she experiences tenderness and slight dryness. What is the next step to take in the clinic?

      Your Answer:

      Correct Answer: Trans-vaginal ultrasound (TVUS)

      Explanation:

      Atrophic vaginitis is a condition that commonly affects women who have gone through menopause. Its symptoms include vaginal dryness, pain during sexual intercourse, and occasional spotting. Upon examination, the vagina may appear dry and pale. The recommended treatment for this condition is the use of vaginal lubricants and moisturizers. If these do not provide relief, a topical estrogen cream may be prescribed.

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      • Gynaecology
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  • Question 15 - A 19-year-old woman visits your GP clinic with her mother to discuss contraceptive...

    Incorrect

    • A 19-year-old woman visits your GP clinic with her mother to discuss contraceptive options. She reports heavy periods and prefers non-invasive methods. She also has a history of migraine with aura. What would be the most suitable option for her?

      Your Answer:

      Correct Answer: Progesterone only contraceptive pill (POCP)

      Explanation:

      There are many options available for contraception, each with their own advantages and disadvantages. It is important to discuss these options to find the best fit for the patient. In this case, the progesterone only contraceptive pill is the most appropriate option due to the patient’s history of migraine with aura and heavy menstrual cycle. The combined oral contraceptive pill is not recommended for this patient. The intrauterine system is a popular option for menorrhagia, but the patient does not want an invasive device. The contraceptive implant is also invasive and not preferred by the patient. Condoms are a good barrier method, but the POCP will also help with the patient’s heavy and irregular periods.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 16 - A 35-year-old woman visits her GP clinic urgently seeking advice as she had...

    Incorrect

    • A 35-year-old woman visits her GP clinic urgently seeking advice as she had unprotected sex last night. She has recently started taking the combined oral contraceptive pill but missed two pills because she forgot to bring them along while on vacation. She is currently in the first week of a new pack. What steps should her GP take now?

      Your Answer:

      Correct Answer: Advise her to take an extra pill today, use barrier contraception for the next 7 days and prescribe emergency contraception

      Explanation:

      If a patient misses 2 pills in the first week of their combined oral contraceptive pill pack and has had unprotected sex during the pill-free interval or week 1, emergency contraception should be considered. The patient should take the missed pills as soon as possible and use condoms for the next 7 days. For patients who have only missed 1 pill, they should take it as soon as possible without needing extra precautions. If extra barrier contraception is needed for patients on the combined oral contraceptive pill, it should be used for at least 7 days. Patients on the progesterone-only pill only need barrier contraception for 2 days. Missing 1 pill at any time throughout a pack or starting a new pack 1 day late generally does not affect protection against pregnancy. Taking more than 2 contraceptive pills in a day is not recommended as it does not provide extra contraceptive effects and may cause side effects.

      Missed Pills in Combined Oral Contraceptive Pill

      When taking a combined oral contraceptive (COC) pill containing 30-35 micrograms of ethinylestradiol, it is important to know what to do if a pill is missed. The Faculty of Sexual and Reproductive Healthcare (FSRH) has updated their recommendations in recent years. If one pill is missed at any time in the cycle, the woman should take the last pill even if it means taking two pills in one day and then continue taking pills daily, one each day. No additional contraceptive protection is needed in this case.

      However, if two or more pills are missed, the woman should take the last pill even if it means taking two pills in one day, leave any earlier missed pills, and then continue taking pills daily, one each day. In this case, the woman should use condoms or abstain from sex until she has taken pills for 7 days in a row. If pills are missed in week 1 (Days 1-7), emergency contraception should be considered if she had unprotected sex in the pill-free interval or in week 1. If pills are missed in week 2 (Days 8-14), after seven consecutive days of taking the COC there is no need for emergency contraception.

      If pills are missed in week 3 (Days 15-21), the woman should finish the pills in her current pack and start a new pack the next day, thus omitting the pill-free interval. Theoretically, women would be protected if they took the COC in a pattern of 7 days on, 7 days off. It is important to follow these guidelines to ensure the effectiveness of the COC in preventing pregnancy.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 17 - A 29-year-old woman had gone for her regular cervical smear test which was...

    Incorrect

    • A 29-year-old woman had gone for her regular cervical smear test which was carried out without any complications. The GP receives the result of the smear indicating that it was positive for high-risk HPV but there were no signs of cytological abnormalities.

      What would be the most suitable course of action to take next?

      Your Answer:

      Correct Answer: Repeat cervical smear in 12 months

      Explanation:

      If a cervical cancer screening sample is positive for high-risk strains of human papillomavirus (hrHPV) but shows no cytological abnormalities, the recommended course of action is to repeat the smear after 12 months. This is in accordance with current guidance. Colposcopy is not necessary in this case. Repeating the smear after 3 months or waiting 3 years for routine recall are also not appropriate. A repeat smear after 6 months would only be necessary after treatment for cervical intraepithelial neoplasia.

      The cervical cancer screening program has evolved to include HPV testing, which allows for further risk stratification. A negative hrHPV result means a return to normal recall, while a positive result requires cytological examination. Abnormal cytology results lead to colposcopy, while normal cytology results require a repeat test at 12 months. Inadequate samples require a repeat within 3 months, and two consecutive inadequate samples lead to colposcopy. Treatment for CIN typically involves LLETZ or cryotherapy. Individuals who have been treated for CIN should be invited for a test of cure repeat cervical sample 6 months after treatment.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 18 - A 29-year-old female patient visits her GP with complaints of vaginal soreness, itchiness,...

    Incorrect

    • A 29-year-old female patient visits her GP with complaints of vaginal soreness, itchiness, and discharge. During the examination, the doctor notices an inflamed vulva and thick, white, lumpy vaginal discharge. The cervix appears normal, but there is discomfort during bimanual examination. The patient has a medical history of asthma, which is well-controlled with salbutamol, and type one diabetes, and has no known allergies. What is the most suitable next step in her care, considering the most probable diagnosis?

      Your Answer:

      Correct Answer: Prescribe oral fluconazole as a single oral dose

      Explanation:

      If a patient presents with symptoms highly suggestive of vaginal candidiasis, a high vaginal swab is not necessary for diagnosis and treatment can be initiated with a single oral dose of fluconazole. Symptoms of vaginal candidiasis include vulval soreness, itching, and thick, white vaginal discharge. Prescribing oral metronidazole as a single dose or taking a high vaginal swab would be incorrect as they are used to treat Trichomonas vaginalis infections or bacterial vaginosis, respectively.

      Vaginal candidiasis, also known as thrush, is a common condition that many women can diagnose and treat themselves. Candida albicans is responsible for about 80% of cases, while other candida species cause the remaining 20%. Although most women have no predisposing factors, certain factors such as diabetes mellitus, antibiotics, steroids, pregnancy, and HIV can increase the likelihood of developing vaginal candidiasis. Symptoms include non-offensive discharge resembling cottage cheese, vulvitis, itching, vulval erythema, fissuring, and satellite lesions. A high vaginal swab is not routinely indicated if the clinical features are consistent with candidiasis. Treatment options include local or oral therapy, with oral fluconazole 150 mg as a single dose being the first-line treatment according to NICE Clinical Knowledge Summaries. If there are vulval symptoms, a topical imidazole may be added to an oral or intravaginal antifungal. Pregnant women should only use local treatments. Recurrent vaginal candidiasis is defined as four or more episodes per year by BASHH. Compliance with previous treatment should be checked, and a high vaginal swab for microscopy and culture should be performed to confirm the diagnosis. A blood glucose test may be necessary to exclude diabetes, and differential diagnoses such as lichen sclerosus should be ruled out. An induction-maintenance regime involving oral fluconazole may be considered. Induction involves taking oral fluconazole every three days for three doses, while maintenance involves taking oral fluconazole weekly for six months.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 19 - A 27-year-old female receives a cervical smear test through the UK cervical screening...

    Incorrect

    • A 27-year-old female receives a cervical smear test through the UK cervical screening programme and is found to be hrHPV positive. However, her cytological examination shows no abnormalities. What is the best course of action to take?

      Your Answer:

      Correct Answer: Repeat the test in 12 months

      Explanation:

      If a cervical smear test is hrHPV positive but cytologically normal, the recommended course of action is to repeat the test in 12 months. This is in contrast to negative hrHPV results, which are returned to normal recall. Abnormal cytology results require colposcopy, but normal cytology results do not. It is important to note that returning to normal recall is not appropriate in this case, as the patient’s higher risk status warrants a repeat test sooner than the standard 3-year interval. Repeating the test within 3 or 6 months is also not recommended.

      The cervical cancer screening program has evolved to include HPV testing, which allows for further risk stratification. A negative hrHPV result means a return to normal recall, while a positive result requires cytological examination. Abnormal cytology results lead to colposcopy, while normal cytology results require a repeat test at 12 months. Inadequate samples require a repeat within 3 months, and two consecutive inadequate samples lead to colposcopy. Treatment for CIN typically involves LLETZ or cryotherapy. Individuals who have been treated for CIN should be invited for a test of cure repeat cervical sample 6 months after treatment.

    • This question is part of the following fields:

      • Gynaecology
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  • Question 20 - A gynaecologist is performing a pelvic examination on a 30-year-old woman in the...

    Incorrect

    • A gynaecologist is performing a pelvic examination on a 30-year-old woman in the lithotomy position. To palpate the patient’s uterus, the index and middle fingers of the right hand are placed inside the vagina, while the fingers and palm of the left hand are used to palpate the abdomen suprapubically. While palpating the patient’s abdomen with her left hand, the doctor feels a bony structure in the lower midline.
      Which one of the following bony structures is the doctor most likely to feel with the palm of her left hand?

      Your Answer:

      Correct Answer: Pubis

      Explanation:

      Anatomy of the Pelvis: Palpable Bones and Structures

      The pelvis is a complex structure composed of several bones and joints. In this scenario, a doctor is examining a patient and can feel a specific bone. Let’s explore the different bones and structures of the pelvis and determine which one the doctor may be palpating.

      Pubis:
      The pubis is one of the three bones that make up the os coxa, along with the ilium and ischium. It is the most anterior of the three and extends medially and anteriorly, meeting with the opposite pubis to form the pubic symphysis. Given the position of the doctor’s hand, it is likely that they are feeling the pubic symphysis and adjacent pubic bones.

      Coccyx:
      The coccyx is the lowest part of the vertebral column and is located inferior to the sacrum. It is composed of 3-5 fused vertebrae and is a posterior structure, making it unlikely to be palpable in this scenario.

      Ilium:
      The ilium is the most superior of the three bones that make up the os coxa. It is a lateral bone and would not be near the position of the doctor’s palm in this scenario.

      Sacrum:
      The sacrum is part of the vertebral column and forms the posterior aspect of the pelvis. It is formed by the fusion of five vertebrae and articulates with the iliac bones via the sacroiliac joints bilaterally. Although it is found in the midline, it is a posterior structure and would not be palpable.

      Ischium:
      The ischium forms the posteroinferior part of the os coxa. Due to its position, it is not palpable in this scenario.

      In conclusion, the doctor is most likely palpating the pubic symphysis and adjacent pubic bones during the examination. Understanding the anatomy of the pelvis and its structures is important for medical professionals to accurately diagnose and treat patients.

    • This question is part of the following fields:

      • Gynaecology
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