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  • Question 1 - The transmembrane proteins responsible for resting membrane potential of vascular smooth muscle cells...

    Incorrect

    • The transmembrane proteins responsible for resting membrane potential of vascular smooth muscle cells was blocked by a drug. Which of the following transmembrane proteins were blocked by this drug?

      Your Answer: Ca2+ channels

      Correct Answer: K+ channels

      Explanation:

      The resting membrane potential is due to selective permeability of the membrane to potassium ions. The Na/K pump is responsible for the generation of a gradient across the membrane and it is due to the inherent ability of the K channels to allow diffusion back into the nerve at rest which charges the cells. In reality, the resting membrane potential is more positive because of small contributions by Na+ channels, Cl− channels and non-selective cation channels.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      12
      Seconds
  • Question 2 - Which of the following is true about myasthenia gravis? ...

    Correct

    • Which of the following is true about myasthenia gravis?

      Your Answer: Response of skeletal muscle to nerve stimulation is weakened

      Explanation:

      An autoimmune disorder, myasthenia gravis leads to progressive muscle weakness. It occurs due to formation of antibodies against the nicotinic acetylcholine (ACh) receptor of the motor endplate, which leads to impaired neuromuscular transmission. Thus, nerve stimulation will lead to a weakened muscle response, but direct electrical stimulation will bring about a normal response. Diagnostic test includes improvement of muscle weakness by small doses of acetylcholinesterase inhibitors (physostigmine or edrophonium). However, a large dose of physostigmine worsens the weakness due to desensitisation of the endplate to persistent Ach. One of the investigative tools includes radiolabelled snake venom α-bungarotoxin. It is an in vitro study performed on muscle biopsy specimens and used to quantify the number of ACh receptors at the motor endplate.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      26.8
      Seconds
  • Question 3 - A man in his sixties underwent surgery to remove a lump from his...

    Incorrect

    • A man in his sixties underwent surgery to remove a lump from his axilla. During removal, a nerve originating from the lateral cord of the brachial plexus was damaged. Which nerve is this referring to?

      Your Answer: Thoracodorsal

      Correct Answer: Lateral pectoral

      Explanation:

      The only branch of the lateral cord of brachial plexus in the options given, is the lateral pectoral nerve. It supplies the pectoralis major muscle and sends a branch to join the medial pectoral nerve forming a loop in front of the first part of the axillary artery.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      17.9
      Seconds
  • Question 4 - Skeletal muscle fibres are divided into two basic types, type I (slow-twitch fibres)...

    Incorrect

    • Skeletal muscle fibres are divided into two basic types, type I (slow-twitch fibres) and type II (fast-twitch fibres). Fast muscle fibres do which of the following:

      Your Answer: Are shorter for great strength of contraction

      Correct Answer: Use anaerobic metabolism

      Explanation:

      Skeletal muscles are divided into two types:
      1) type I also known as the slow twitch fibres. They use oxygen for their metabolism and as a result they have a high endurance potential. To support this they have abundant mitochondria and myoglobin, so they appear red/dark.
      2) type II fibres also called fast twitch fibres, are low endurance fibres used during anaerobic metabolism. They are required for short bursts of strength and cannot sustain contractions for long periods of time.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      13.8
      Seconds
  • Question 5 - A 42 year old man with an abdominal aortic aneurysm (AAA) underwent an...

    Incorrect

    • A 42 year old man with an abdominal aortic aneurysm (AAA) underwent an abdominal aortic angiography which revealed that his inferior mesenteric artery was occluded. If this patient showed no symptoms, the most likely reason is that the area the inferior mesenteric artery supplies, must be supplied by collateral blood flow from which arteries?

      Your Answer: Ileocolic and right colic

      Correct Answer: Left and middle colic

      Explanation:

      The arterial branches that form an anastomosis between the superior mesenteric artery and the inferior mesenteric artery are the left colic artery and the middle colic artery. The middle colic artery is the most distal branch of the superior mesenteric artery while the left colic forms the most proximal branch of the inferior mesenteric artery. These two arteries will give collateral blood flow in the case that the inferior mesenteric artery gets occluded. The superior mesenteric artery gives off the following branches; ileocolic, appendicular, ileal artery, right colic and middle colic arteries. The left colic, sigmoid and superior rectal arteries are branches of the inferior mesenteric artery. The marginal artery branches off directly from the abdominal aorta.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      49.4
      Seconds
  • Question 6 - In order to arrest sudden bleeding during pericardiectomy that started after accidental injury...

    Incorrect

    • In order to arrest sudden bleeding during pericardiectomy that started after accidental injury to a major vasculature in the pericardium; the surgeon inserted his left index finger through the transverse pericardial sinus, pulled forward on the two large vessels lying ventral to his finger, and compressed these vessels with his thumb to control the bleeding. Which vessels were these?

      Your Answer: Pulmonary trunk and superior vena cava

      Correct Answer: Pulmonary trunk and aorta

      Explanation:

      Transverse pericardial sinus: located behind two great vessels (aorta and pulmonary trunk) and in front of the superior vena cava and is accessed from above as in this case. The brachiocephalic trunk is located above the pericardium and the right pulmonary artery is above the pericardial reflections.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      47.2
      Seconds
  • Question 7 - What will the destruction of endoplasmic reticulum stop? ...

    Correct

    • What will the destruction of endoplasmic reticulum stop?

      Your Answer: Synthesis of proteins

      Explanation:

      The rough endoplasmic reticulum is the factory for the manufacturing of proteins. It contains ribosomes attached to it and transports proteins that are destined for membranes and secretions. The rough ER is connected to the nuclear envelope and to the cisternae of the Golgi apparatus by vesicles that shuttle between the two compartments.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      22.6
      Seconds
  • Question 8 - A patient is unable to move the mandible to the left. Which muscle...

    Incorrect

    • A patient is unable to move the mandible to the left. Which muscle is affected in this case?

      Your Answer: Left lateral pterygoid muscle

      Correct Answer: Right lateral pterygoid muscle

      Explanation:

      Patients with paralysis of the right pterygoid muscle are unable to move their mandible laterally to the left.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      18.9
      Seconds
  • Question 9 - A 40 year old man sustained a fracture to the surgical neck of...

    Correct

    • A 40 year old man sustained a fracture to the surgical neck of his left humerus. Which of the following arteries is suspected to be injured in this case?

      Your Answer: Posterior humeral circumflex

      Explanation:

      The posterior humeral circumflex artery arises from the axillary artery and runs with the axillary nerve through the quadrangular space which is bounded laterally by the surgical neck of the humerus. After winding around the surgical neck of the humerus, it is distributed to the deltoid muscle and the shoulder joint. Thus fractures in the surgical neck of the humerus could result in an injury to this artery.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      20.2
      Seconds
  • Question 10 - Which of the following substances is most likely to cause pulmonary vasodilatation? ...

    Correct

    • Which of the following substances is most likely to cause pulmonary vasodilatation?

      Your Answer: Nitric oxide

      Explanation:

      In the body, nitric oxide is synthesised from arginine and oxygen by various nitric oxide synthase (NOS) enzymes and by sequential reduction of inorganic nitrate. The endothelium of blood vessels uses nitric oxide to signal the surrounding smooth muscle to relax, so dilating the artery and increasing blood flow. Nitric oxide/oxygen blends are used in critical care to promote capillary and pulmonary dilation to treat primary pulmonary hypertension in neonatal patients post-meconium aspiration and related to birth defects.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      1116.1
      Seconds
  • Question 11 - Nephrotic syndrome is a condition that causes proteinuria, hypoalbuminemia and oedema. Which of...

    Correct

    • Nephrotic syndrome is a condition that causes proteinuria, hypoalbuminemia and oedema. Which of the following is the cause of the oedema in these patients?

      Your Answer: Decreased oncotic pressure

      Explanation:

      The glomeruli of the kidneys are the parts that normally filter the blood. They consist of capillaries that are fenestrated and allow fluid, salts and other small solutes to flow through, but normally not proteins. In nephrotic syndrome, the glomeruli become damaged allowing small proteins, such as albumin to pass through the kidneys into urine. Oedema usually occurs due to salt and water retention by the diseased kidneys as well as due to the reduced colloid oncotic pressure (because of reduced albumin in the plasma). Lower serum oncotic pressure causes fluid to accumulate in the interstitial tissues.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      9.9
      Seconds
  • Question 12 - The Brunner glands secrete an alkaline product that helps maintain an optimal pH...

    Incorrect

    • The Brunner glands secrete an alkaline product that helps maintain an optimal pH for pancreatic enzyme activity. Where are these glands located?

      Your Answer: Submucosa of the ileum

      Correct Answer: Submucosa of the duodeneum

      Explanation:

      The Brunner glands are located in the submucosa of the duodenum. These glands are connected to the interstitial lumen by ducts that open into certain crypts. They secrete an alkaline product that protects the duodenal mucosa from the acidic chyme and helps achieve an optimal pH for the enzymes.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      26.1
      Seconds
  • Question 13 - 13 year old girl developed sun burnt cheeks after spending the day playing...

    Correct

    • 13 year old girl developed sun burnt cheeks after spending the day playing on the beach. What is the underlying mechanism to her injury?

      Your Answer: Free radical injury

      Explanation:

      Free radicals are a by-product of chemical reactions with an unpaired electron in their outer most shell. They are capable of causing wide spread damage to cells. They can cause autolytic reactions thereby converting the reactants into free radicals. By absorbing sun light, the energy is used to hydrolyse water into hydroxyl (OH) and hydrogen (H) free radicals which can cause injury by lipid peroxidation of membranes, oxidative modification of proteins and damage to the DNA structure.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      12.2
      Seconds
  • Question 14 - The Henderson–Hasselbalch equation describes the derivation of pH as a measure of acidity. According to this equation,...

    Incorrect

    • The Henderson–Hasselbalch equation describes the derivation of pH as a measure of acidity. According to this equation, the buffering capacity of the system is at maximum when the number of free anions compared with undissociated acid is:

      Your Answer: Two times more

      Correct Answer: Equal

      Explanation:

      In 1908, Lawrence Joseph Henderson wrote an equation describing the use of carbonic acid as a buffer solution. Later, Karl Albert Hasselbalch re-expressed that formula in logarithmic terms, resulting in the Henderson–Hasselbalch equation. The equation is also useful for estimating the pH of a buffer solution and finding the equilibrium pH in acid–base reactions. Two equivalent forms of the equation are: pH = pKa + log10 [A–]/[HA] or pH = pKa + log10 [base]/[acid]. Here, pKa is − log10(Ka) where Ka is the acid dissociation constant, that is: pKa = –log10(Ka) = –log10 ([H3 O+][A–]/[HA]) for the reaction: HA + H2 O ≈ A– + H3 O+ In these equations, A– denotes the ionic form of the relevant acid. Bracketed quantities such as [base] and [acid] denote the molar concentration of the quantity enclosed. Maximum buffering capacity is found when pH = pKa or when the number of free anions to undissociated acid is equal and buffer range is considered to be at a pH = pKa ± 1.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      43.6
      Seconds
  • Question 15 - A 20-year-old woman presents with a posteriorly-sited anal fissure. Treatment with stool softeners...

    Incorrect

    • A 20-year-old woman presents with a posteriorly-sited anal fissure. Treatment with stool softeners and topical GTN have failed to improve the condition. Which of the following would be the most appropriate next step of management?

      Your Answer: Lateral internal sphincterotomy

      Correct Answer: Injection of botulinum toxin

      Explanation:

      The most appropriate management option to consider, after GTN or other topical nitrates have failed, is botulinum toxin injection. In males, a lateral internal sphincterotomy would be an acceptable alternative. In a female who has yet to conceive, this may predispose to an increased risk of sphincter dysfunction. Moreover, division of the external sphincter would result in faecal incontinence and is not a justified treatment for anal fissure.

      Anal fissures are a common cause of painful, bright red rectal bleeding. Most fissures are idiopathic and present as a painful mucocutaneous defect in the posterior midline (90% cases). Fissures are more likely to be anteriorly located in females, particularly if they are multiparous. Diseases associated with fissure-in-ano include:
      1. Crohn’s disease
      2. Tuberculosis
      3. Internal rectal prolapse

      Diagnostic options are as follows:
      In most cases, the defect can be visualised as a posterior midline epithelial defect. Where symptoms are highly suggestive of the condition and examination findings are unclear, an examination under anaesthesia may be helpful. Atypical disease presentation should be investigated by colonoscopy and EUA, with biopsies of the area.

      For management of anal fissure:
      1. Stool softeners are important as hard stools may tear the epithelium and result in recurrent symptoms. The most effective first-line agents are topically applied GTN (0.2%) or Diltiazem (2%) paste.
      2. Resistant cases may benefit from injection of botulinum toxin or lateral internal sphincterotomy. Advancement flaps may be used to treat resistant cases.

    • This question is part of the following fields:

      • Colorectal Surgery
      • Generic Surgical Topics
      26.4
      Seconds
  • Question 16 - A 46 year old man had an upper gastrointestinal endoscopy and biopsies done...

    Correct

    • A 46 year old man had an upper gastrointestinal endoscopy and biopsies done which were reported by two gastrointestinal pathologists as being ‘indefinite for dysplasia.’ Repeat endoscopy and biopsies were repeated 6 months after completing treatment with proton pump inhibitors. The results revealed no definite evidence of dysplasia. What is the most appropriate management?

      Your Answer: Routine surveillance every 2–3 years

      Explanation:

      This patient had endoscopy and biopsy done by different doctors and proton pump inhibitor therapy followed by repeat endoscopy and biopsy six months later which had no definite evidence of dysplasia.

      British Society of Gastroenterology (BSG) guidelines state that for patients with Barrett’s oesophagus (BO) but without dysplasia, the recommended surveillance protocols are two yearly, four quadrant biopsies every 2 cm, but jumbo biopsies are not required.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Upper Gastrointestinal Surgery
      18.5
      Seconds
  • Question 17 - A 34 year old woman underwent a wide local excision for her breast...

    Incorrect

    • A 34 year old woman underwent a wide local excision for her breast carcinoma. Histology reveals an invasive lobular carcinoma present at three of the resection margins. Cavity shavings that were taken at the original operation are also involved. The sentinel lymph node biopsy was reported to be negative. Which of the following management plans would be the most appropriate for this patient?

      Your Answer:

      Correct Answer: Arrange for completion mastectomy alone

      Explanation:

      Mastectomy should ideally be done in this patient. This patient has extensive spread of disease and tumour margins are unclear which makes radiotherapy the less likely option. Mastectomy is the safest option in this scenario. Patients who have undergone mastectomy may be offered a reconstructive procedure either in conjunction with their primary resection or as a staged procedure at a later date.

    • This question is part of the following fields:

      • Breast And Endocrine Surgery
      • Generic Surgical Topics
      0
      Seconds
  • Question 18 - Which of the following is likely to result in hematocolpos in a 12-year...

    Incorrect

    • Which of the following is likely to result in hematocolpos in a 12-year old girl?

      Your Answer:

      Correct Answer: Imperforate hymen

      Explanation:

      Hematocolpos means accumulation of blood in vagina and hematometra is accumulation of blood in the uterus. These are most likely seen with an imperforate hymen; which is seen I 1 in 2000 females. If spontaneous resolution does not occur, treatment involves making a hole in the hymen to allow discharge of menstrual blood.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
      Seconds
  • Question 19 - A 27-year-old professional tennis player presents to the A&E department with a swollen,...

    Incorrect

    • A 27-year-old professional tennis player presents to the A&E department with a swollen, painful right arm. On examination, his fingers are dusky. Out of the following, which is the most appropriate investigation?

      Your Answer:

      Correct Answer: Venous duplex scan

      Explanation:

      This patient has an axillary vein thrombosis. It classically presents with pain and swelling of the affected limb. Venous duplex scan is needed to exclude a thrombus.

      Primary proximal upper-extremity deep vein thrombosis (UEDVT) is less common than its secondary forms. The most common primary form is effort-related thrombosis, also called Paget-Schroetter syndrome. It usually occurs in, otherwise, healthy young men who report, before the onset of thrombosis, vigorous arm exercise such as lifting weights, playing badminton/tennis, pitching a baseball, or performing repetitive overhead activities, such as painting or car repair. Most patients with effort-related UEDVT have an underlying venous thoracic outlet syndrome (VTOS). Secondary causes of UEDVT include central line insertion, malignancy, or pacemakers.

      Patients with UEDVT typically present with heaviness, discomfort, pain, paraesthesia, and swelling of the affected arm. Physical examination may reveal pitting oedema, redness, or cyanosis of the involved extremity; visible collateral veins at the shoulder or upper arm; and fever.

      Diagnosis is made by:
      1. FBC: platelet function
      2. Coagulation profile
      3. Liver function tests
      4. Venous duplex scan: investigation of choice, provides information relating to flow and characteristics of the vessels.
      5. D-dimer testing
      6. CT scan: for VTOS

      Treatment options for primary UEDVT are as follows:
      1. Anticoagulation therapy should be undertaken with a once-daily regimen of LMWH or fondaparinux for at least five days, followed by vitamin K antagonists for at least three months. Unfractionated heparin instead of LMWH is recommended for patients with renal failure or for those treated with CDT.

      2. Early thrombus removal and restoration of venous patency aim should be done immediately after starting the patient on heparin. Catheter-based therapy is recommended for patients with proximal UEDVT of recent onset and severe symptoms, low risk for bleeding complications, and good functional status.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Vascular
      0
      Seconds
  • Question 20 - A 23-year-old male is involved in a road traffic accident. He is thrown...

    Incorrect

    • A 23-year-old male is involved in a road traffic accident. He is thrown from his motorbike onto the pavement and sustains a haemopneumothorax and flail segment of the right chest. What should be the most appropriate course of action?

      Your Answer:

      Correct Answer: Insertion of intercostal chest tube

      Explanation:

      This patient requires immediate insertion of an intercostal chest tube and analgesia. In general, all cases of haemopneumothorax should be managed by intercostal chest drain insertion as it can develop into tension pneumothorax until the lung laceration has sealed.

      Haemopneumothorax is most frequently caused by a trauma or blunt or penetrating injury to the chest followed by laceration of the lung with air leakage, or injury to the intercostal vessels or internal mammary artery. The main treatment for haemopneumothorax is chest tube thoracostomy (chest tube insertion). Surgical exploration is warranted if >1500ml blood is drained immediately.

      Flail chest occurs when the chest wall disconnects from the thoracic cage. It usually follows multiple rib fractures (at least two fractures per rib in at least two ribs) and is associated with pulmonary contusion. Overhydration and fluid overload is avoided in such patients.

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
      0
      Seconds
  • Question 21 - The rotator cuff surrounds the shoulder joint and consists of the supraspinatus, infraspinatus,...

    Incorrect

    • The rotator cuff surrounds the shoulder joint and consists of the supraspinatus, infraspinatus, subscapularis and which one other muscle?

      Your Answer:

      Correct Answer: Teres minor

      Explanation:

      The correct answer is the teres minor muscle. These group of muscles play an important role in protecting the shoulder joint and keeping the head of the humerus in the glenoid fossa of the scapula. This fossa is somehow shallow and needs support to allow for the full mobility that the shoulder joint has.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      0
      Seconds
  • Question 22 - A young man is hit in the head with a bar stool and...

    Incorrect

    • A young man is hit in the head with a bar stool and is rushed to the A&E department. On arrival, he opens his eyes in response to pain, his only verbal responses are in the form of groans and grunts. He flexes his forearms away from the painful stimuli when it is applied. Calculate his Glasgow coma score.

      Your Answer:

      Correct Answer: 8

      Explanation:

      Answer: 8

      Eye Opening Response
      Spontaneous–open with blinking at baseline – 4 points
      Opens to verbal command, speech, or shout – 3 points
      Opens to pain, not applied to face – 2 point
      None – 1 point

      Verbal Response
      Oriented – 5 points
      Confused conversation, but able to answer questions – 4 points
      Inappropriate responses, words discernible – 3 points
      Incomprehensible speech – 2 points
      None – 1 point

      Motor Response
      Obeys commands for movement – 6 points
      Purposeful movement to painful stimulus – 5 points
      Withdraws from pain – 4 points
      Abnormal (spastic) flexion, decorticate posture – 3 points
      Extensor (rigid) response, decerebrate posture – 2 points
      None – 1 point

      He opens his eyes to pain and groans or grunts. He flexes his forearms away from the painful stimuli This gives him a Glasgow score of 8: eye opening response of 2, verbal response 2 and motor response 4.

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
      0
      Seconds
  • Question 23 - A 3-year-old boy is brought to the A&E department following a trauma. He...

    Incorrect

    • A 3-year-old boy is brought to the A&E department following a trauma. He is haemodynamically unstable. Initial attempts at intravenous access are proving unsuccessful.What should be the best course of action?

      Your Answer:

      Correct Answer: Insert an intraosseous infusion system

      Explanation:

      Gaining venous access in small children is challenging most of the times especially in cases of trauma. Therefore, intraosseous infusions should be preferred in this setting. Broviac lines are long-term IV access systems with narrow lumens and, hence, would be unsuitable.

      Intraosseous access is typically undertaken at the anteromedial aspect of the proximal tibia and provides access to the marrow cavity and circulatory system. Although traditionally preferred in paediatric practice, it may be used in adults as well, and a wide range of fluids can be infused using this approach.

    • This question is part of the following fields:

      • Peri-operative Care
      • Principles Of Surgery-in-General
      0
      Seconds
  • Question 24 - A 39 year old hiker slips down a slope and injures her hand...

    Incorrect

    • A 39 year old hiker slips down a slope and injures her hand on an oak tree. On examination, she is tender in the anatomical snuffbox and on bimanual palpation. X-rays with scaphoid views show no evidence of fracture. What is the most appropriate course of action?

      Your Answer:

      Correct Answer: Application of futura splint and fracture clinic review

      Explanation:

      A scaphoid fracture is a break of the scaphoid bone in the wrist. Symptoms generally include pain at the base of the thumb which is worse with use of the hand. The anatomic snuffbox is generally tender and swelling may occur. Complications may include non-union of the fracture, avascular necrosis, and arthritis.

      Scaphoid fractures are most commonly caused by a fall on an outstretched hand. Diagnosis is generally based on examination and medical imaging. Some fractures may not be visible on plain X-rays. In such cases a person may be casted with repeat X-rays in two weeks or an MRI or bone scan may be done.
      Scaphoid fractures are often diagnosed by PA and lateral X-rays. However, not all fractures are apparent initially. Therefore, people with tenderness over the scaphoid (those who exhibit pain to pressure in the anatomic snuff box) are often splinted in a thumb spica for 7–10 days at which point a second set of X-rays is taken. If there was a hairline fracture, healing may now be apparent. Even then a fracture may not be apparent. A CT Scan can then be used to evaluate the scaphoid with greater resolution. The use of MRI, if available, is preferred over CT and can give one an immediate diagnosis. Bone scintigraphy is also an effective method for diagnosing a fracture which does not appear on x-ray.

    • This question is part of the following fields:

      • Generic Surgical Topics
      • Orthopaedics
      0
      Seconds
  • Question 25 - Whilst snorkelling, a 30-year old gentleman has the respiratory rate of 10/min, tidal...

    Incorrect

    • Whilst snorkelling, a 30-year old gentleman has the respiratory rate of 10/min, tidal volume of 550 ml and an effective anatomical dead space of 250 ml. Which of the following will bring about a maximum increase in his alveolar ventilation?

      Your Answer:

      Correct Answer: A 2x increase in tidal volume and a shorter snorkel

      Explanation:

      Alveolar ventilation = respiratory rate × (tidal volume − anatomical dead space volume). Increase in respiratory rate simply causes movement of air in the anatomical dead space, with no contribution to the alveolar ventilation. By use of a shorter snorkel, the effective anatomical dead space will decrease and will cause a maximum rise in alveolar ventilation along with doubling of tidal volume.

    • This question is part of the following fields:

      • Basic Sciences
      • Physiology
      0
      Seconds
  • Question 26 - A man was stabbed in the thigh following a bar brawl. A superficial...

    Incorrect

    • A man was stabbed in the thigh following a bar brawl. A superficial vein was injured which terminates in the femoral vein. This superficial vein is?

      Your Answer:

      Correct Answer: Great saphenous

      Explanation:

      The great saphenous vein is considered the longest vein in the body. It terminates in the femoral vein nearly 3cm below the inguinal ligament. It begins at the dorsum of the foot in the medial marginal vein and ascends at the medial side of the leg in relation with the saphenous nerve.

    • This question is part of the following fields:

      • Anatomy
      • Basic Sciences
      0
      Seconds
  • Question 27 - A 27 year old women works in a dry-cleaning shop. She was exposed...

    Incorrect

    • A 27 year old women works in a dry-cleaning shop. She was exposed to massive amounts of carbon tetrachloride on her skin as well as inhaled. Which of the following organs is most susceptible to damage?

      Your Answer:

      Correct Answer: Liver

      Explanation:

      Carbon tetrachloride (CCl4) is a common agent used in the dry cleaning industry and is thought to cause the formation of free radicals. It causes rapid breakdown of the endoplasmic reticulum due to decomposition of lipids and severe liver cell injury. Within less than 30 mins, hepatic protein synthesis declines, lipid export is reduced due to lack of apoprotein and there is an influx of calcium and cell death.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
      Seconds
  • Question 28 - A new-born was found to have an undeveloped spiral septum in the heart....

    Incorrect

    • A new-born was found to have an undeveloped spiral septum in the heart. This is characteristic of which of the following?

      Your Answer:

      Correct Answer: Persistent truncus arteriosus

      Explanation:

      Persistent truncus arteriosus is a congenital heart disease that occurs when the primitive truncus does not divide into the pulmonary artery and aorta, resulting in a single arterial trunk. The spiral septum is created by fusion of a truncal septum and the aorticopulmonary spiral septum. Incomplete development of these septa results in incomplete separation of the common tube of the truncus arteriosus and the aorticopulmonary trunk.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
      0
      Seconds
  • Question 29 - A 24 year old man hits his head during a fall whilst he...

    Incorrect

    • A 24 year old man hits his head during a fall whilst he is intoxicated. He is taken to the doctor and is disorientated despite opening his eyes in response to speech and being able to talk. He is also able to obey motor commands. What would be his Glasgow coma score?

      Your Answer:

      Correct Answer: 13

      Explanation:

      Answer: 13

      Eye Opening Response
      Spontaneous–open with blinking at baseline – 4 points
      Opens to verbal command, speech, or shout – 3 points
      Opens to pain, not applied to face – 2 point
      None – 1 point

      Verbal Response
      Oriented – 5 points
      Confused conversation, but able to answer questions – 4 points
      Inappropriate responses, words discernible – 3 points
      Incomprehensible speech – 2 points
      None – 1 point

      Motor Response
      Obeys commands for movement – 6 points
      Purposeful movement to painful stimulus – 5 points
      Withdraws from pain – 4 points
      Abnormal (spastic) flexion, decorticate posture – 3 points
      Extensor (rigid) response, decerebrate posture – 2 points
      None – 1 point

      He is seen to be disorientated despite opening his eyes in response to speech and being able to talk. He is also able to obey motor commands. His score is therefore 13: 3 for eye opening response, 4 for verbal response and 6 for motor response.

    • This question is part of the following fields:

      • Emergency Medicine And Management Of Trauma
      • Principles Of Surgery-in-General
      0
      Seconds
  • Question 30 - What class of drugs does buspirone belong to? ...

    Incorrect

    • What class of drugs does buspirone belong to?

      Your Answer:

      Correct Answer: Anxiolytic

      Explanation:

      Buspirone is an anxiolytic agent and a serotonin-receptor agonist that belongs to the azaspirodecanedione class of compounds. It shows no potential for addiction compared with other drugs commonly prescribed for anxiety, especially the benzodiazepines. The development of tolerance has not been noted. It is primarily used to treat generalized anxiety disorders. It is also commonly used to augment antidepressants in the treatment of major depressive disorder.

    • This question is part of the following fields:

      • Basic Sciences
      • Pathology
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