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Question 1
Incorrect
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A 28-year-old man comes to the emergency department complaining of decreased vision in his left eye. He reports that he first noticed it approximately 4 hours ago and is experiencing pain, particularly when he moves his eye. Additionally, he notes that everything appears to be a strange color.
During the examination, the swinging light test reveals normal constriction of both pupils when the light is directed into the right eye. However, when the light is directed into the left eye, there is a reduced constriction of both pupils.
What is the most common disease that could be causing this man's symptoms?Your Answer: Ankylosing spondylitis
Correct Answer: Multiple sclerosis
Explanation:The patient’s symptoms suggest optic neuritis, which is commonly caused by multiple sclerosis. This condition involves inflammation of the optic nerve, resulting in pain on movement, reduced visual acuity, and an RAPD due to reduced response to light in the affected eye. Multiple sclerosis is a demyelinating disease that can cause various symptoms, including optic neuritis, by damaging the myelin sheaths of nerves.
Rheumatoid arthritis is an autoimmune condition that primarily affects the joints but can also cause extra-articular manifestations throughout the body. In the eye, it tends to cause scleritis, episcleritis, and keratoconjunctivitis sicca, but not optic neuritis.
Behçet’s disease is another inflammatory disorder that affects multiple parts of the body, but its ocular manifestation is anterior uveitis, not optic neuritis.
Ulcerative colitis is an inflammatory bowel disease that involves inflammation of the lower GI tract. It can also cause extraintestinal manifestations, including scleritis and anterior uveitis in the eye.
Optic neuritis is a condition that can be caused by multiple sclerosis, diabetes, or syphilis. It is characterized by a decrease in visual acuity in one eye over a period of hours or days, as well as poor color discrimination and pain that worsens with eye movement. Other symptoms include a relative afferent pupillary defect and a central scotoma. The condition can be diagnosed through an MRI of the brain and orbits with gadolinium contrast. Treatment typically involves high-dose steroids, and recovery usually takes 4-6 weeks. If an MRI shows more than three white-matter lesions, the risk of developing multiple sclerosis within five years is approximately 50%.
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This question is part of the following fields:
- Ophthalmology
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Question 2
Incorrect
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A 45-year-old man visits his GP complaining of burning and itching of his eyelids, particularly in the mornings. He reports feeling dryness and grittiness in his eyes and has stopped using contact lenses, opting for glasses instead. Upon examination, the GP notes redness, crusting, and slight swelling of the eyelid margins, as well as a small chalazion on the lower right lid. The patient's visual acuity remains unchanged and both conjunctivae are clear. What is the recommended first-line treatment?
Your Answer: Steroid eye drops
Correct Answer: Regular lid hygiene
Explanation:The initial and most important treatment for blepharitis, a common and chronic condition, is regular lid hygiene. Although there are different types of blepharitis, lid hygiene is the first-line treatment for all of them. The goal is to clear out any stagnant oily secretions, unblock meibomian glands, remove bacteria and flakes of skin, and soothe the eyelids. Patients should practice lid hygiene twice daily, which involves warmth, massage, and cleansing. There are many patient information leaflets available online that explain the process. Oral tetracycline is not the first-line treatment for blepharitis and is usually unnecessary if lid hygiene measures are followed. If symptoms persist, a course of oral tetracycline may be considered, especially in cases where meibomian gland dysfunction is prominent and there is associated rosacea. Sodium cromoglicate eye drops are not used in the management of blepharitis, as they are intended for allergic eye disease. Steroid eye drops are not a primary care treatment option for blepharitis and are not first-line, although they may be considered by specialists in cases resistant to other treatment measures.
Blepharitis is a condition where the eyelid margins become inflamed. This can be caused by dysfunction of the meibomian glands (posterior blepharitis) or seborrhoeic dermatitis/staphylococcal infection (anterior blepharitis). It is more common in patients with rosacea. The meibomian glands secrete oil to prevent rapid evaporation of the tear film, so any problem affecting these glands can cause dryness and irritation of the eyes. Symptoms of blepharitis are usually bilateral and include grittiness, discomfort around the eyelid margins, sticky eyes in the morning, and redness of the eyelid margins. Styes and chalazions are also more common in patients with blepharitis, and secondary conjunctivitis may occur.
Management of blepharitis involves softening the lid margin with hot compresses twice a day and practicing lid hygiene to remove debris from the lid margins. This can be done using cotton wool buds dipped in a mixture of cooled boiled water and baby shampoo or sodium bicarbonate in cooled boiled water. Artificial tears may also be given for symptom relief in people with dry eyes or an abnormal tear film.
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This question is part of the following fields:
- Ophthalmology
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Question 3
Correct
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A 35-year-old Arabic woman visits the GP clinic complaining of vision issues. She reports experiencing increasing haziness in both eyes for the past 2 years. Upon further inquiry, she discloses a history of recurrent tetany and seizures. During fundoscopy, you observe a lack of red reflex in both eyes. Additionally, both Chvostek sign and Trousseau sign are positive. She has no significant medical history and is not taking any medications. Her blood test results are as follows:
HbA1c 40 mmol/mol
What is the probable cause of her visual problem?Your Answer: Hypocalcaemia
Explanation:The positive Chvostek and Trousseau signs, along with a history of tetany and convulsions, suggest that the patient is suffering from hypocalcaemia. This condition can lead to cataracts, which may explain the patient’s vision problems. It is unlikely that the cataracts are related to age, as the patient is still young. Hypercalcaemia is not a common cause of cataracts, and the patient is not taking steroids, which can also cause cataracts. Additionally, the patient’s normal HbA1c indicates that she does not have diabetes mellitus.
Understanding Cataracts: Causes, Symptoms, and Management
A cataract is a common eye condition that affects the lens of the eye, causing it to become cloudy and reducing the amount of light that reaches the retina. This can lead to blurred or reduced vision, making it difficult to see clearly. Cataracts are more common in women and tend to increase in incidence with age. While the normal ageing process is the most common cause, other factors such as smoking, alcohol consumption, trauma, diabetes, and long-term corticosteroid use can also contribute to the development of cataracts.
Symptoms of cataracts include reduced vision, faded colour vision, glare, and halos around lights. A defect in the red reflex is also a sign of cataracts. Diagnosis is typically made through ophthalmoscopy and slit-lamp examination, which can reveal the presence of a visible cataract.
In the early stages, age-related cataracts can be managed conservatively with stronger glasses or contact lenses and brighter lighting. However, surgery is the only effective treatment for cataracts and involves removing the cloudy lens and replacing it with an artificial one. Referral for surgery should be based on the presence of visual impairment, impact on quality of life, and patient choice. Complications following surgery can include posterior capsule opacification, retinal detachment, posterior capsule rupture, and endophthalmitis.
Overall, cataracts are a common and treatable eye condition that can significantly impact a person’s vision. Understanding the causes, symptoms, and management options can help individuals make informed decisions about their eye health.
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This question is part of the following fields:
- Ophthalmology
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Question 4
Incorrect
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A 28-year-old pregnant woman came to your GP clinic complaining of mild pain and redness in both eyes that had been present for a week. During the examination, you noticed diffuse conjunctival injection with some purulent discharges and crusted eyelids. What is the ONE treatment you should initiate for this patient?
Your Answer: Chloramphenicol ointment
Correct Answer: Fusidic acid eye drops
Explanation:Pregnant women with bacterial conjunctivitis should use topical fusidic acid eye drops for treatment. It is not recommended to use chloramphenicol ointment or eye drops in pregnant patients. Oral antibiotics are typically unnecessary for treating bacterial conjunctivitis, and steroid eye drops are not effective. While viral conjunctivitis can be monitored without treatment, bacterial conjunctivitis requires prompt treatment with topical antibiotics to prevent a secondary bacterial infection.
Conjunctivitis is a common eye problem that is often seen in primary care. It is characterized by red, sore eyes with a sticky discharge. There are two types of infective conjunctivitis: bacterial and viral. Bacterial conjunctivitis is identified by a purulent discharge and eyes that may be stuck together in the morning. On the other hand, viral conjunctivitis is characterized by a serous discharge and recent upper respiratory tract infection, as well as preauricular lymph nodes.
In most cases, infective conjunctivitis is a self-limiting condition that resolves without treatment within one to two weeks. However, topical antibiotic therapy is often offered to patients, such as Chloramphenicol drops given every two to three hours initially or Chloramphenicol ointment given four times a day initially. Alternatively, topical fusidic acid can be used, especially for pregnant women, and treatment is twice daily.
For contact lens users, topical fluoresceins should be used to identify any corneal staining, and treatment should be the same as above. During an episode of conjunctivitis, contact lenses should not be worn, and patients should be advised not to share towels. School exclusion is not necessary.
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This question is part of the following fields:
- Ophthalmology
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Question 5
Incorrect
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A 42-year-old patient with ankylosing spondylitis complains of sudden pain in the right eye and blurry vision. During examination, you observe redness around the cornea and a constricted pupil. Ophthalmoscopy reveals difficulty in visualizing the retina due to the patient's intolerance to bright light, but you do notice a fluid level at the front of the eye. What is the probable diagnosis?
Your Answer: Scleritis
Correct Answer: Anterior uveitis
Explanation:Anterior uveitis, also known as iritis, is a type of inflammation that affects the iris and ciliary body in the front part of the uvea. It is a common cause of red eye and is associated with HLA-B27, which may also be linked to other conditions. Symptoms of anterior uveitis include sudden onset of eye discomfort and pain, small or irregular pupils, intense sensitivity to light, blurred vision, redness, tearing, and the presence of pus and inflammatory cells in the front part of the eye. This condition may be associated with ankylosing spondylitis, reactive arthritis, ulcerative colitis, Crohn’s disease, Behcet’s disease, and sarcoidosis. Urgent review by an ophthalmologist is necessary, and treatment may involve the use of cycloplegics and steroid eye drops.
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This question is part of the following fields:
- Ophthalmology
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Question 6
Correct
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A 68-year-old woman visits the general practice clinic with complaints of itchy eyes and crusting on the eyelids. During examination, the upper lids near the eyelash follicles have small flakes of skin, and the eyelids are slightly swollen.
What is the most suitable initial treatment for this patient's condition?Your Answer: Warm compresses and eyelid hygiene
Explanation:Treatment Options for Blepharitis
Blepharitis is a common eye condition that causes inflammation of the eyelids. The most appropriate first-line treatment for blepharitis is self-care measures such as eyelid hygiene and warm compresses. This involves cleaning the eyelids with warm water and a diluted cleanser such as baby shampoo twice a day, and applying a warm compress to the closed eyelids for 5-10 minutes once or twice a day.
Topical steroids are not recommended for the treatment of blepharitis, but may be used by secondary care clinicians to reduce inflammation. Topical chloramphenicol may be prescribed for anterior blepharitis if eyelid hygiene and warm compresses are ineffective, while oral tetracycline may be prescribed for posterior blepharitis with meibomian gland dysfunction and rosacea if self-care measures are ineffective.
It is important to note that topical ketoconazole is not recommended for the treatment of blepharitis, as it is used for other conditions such as fungal skin infections and candidiasis. If self-care measures and prescribed treatments do not improve symptoms, further treatment or referral may be recommended.
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This question is part of the following fields:
- Ophthalmology
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Question 7
Incorrect
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A 25-year-old male with a history of ankylosing spondylitis presents to the emergency department with a painful red eye, photophobia, lacrimation, and reduced visual acuity. On examination, an irregularly shaped pupil is noted. What is the most suitable approach to manage this patient's current condition?
Your Answer: Acetazolamide and cycloplegic (mydriatic) eye drops
Correct Answer: Steroid and cycloplegic (mydriatic) eye drops
Explanation:Anterior uveitis, also known as iritis, is a type of inflammation that affects the iris and ciliary body in the front part of the uvea. It is a common cause of red eye and is associated with HLA-B27, which may also be linked to other conditions. Symptoms of anterior uveitis include sudden onset of eye discomfort and pain, small or irregular pupils, intense sensitivity to light, blurred vision, redness, tearing, and the presence of pus and inflammatory cells in the front part of the eye. This condition may be associated with ankylosing spondylitis, reactive arthritis, ulcerative colitis, Crohn’s disease, Behcet’s disease, and sarcoidosis. Urgent review by an ophthalmologist is necessary, and treatment may involve the use of cycloplegics and steroid eye drops.
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This question is part of the following fields:
- Ophthalmology
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Question 8
Correct
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A 55-year-old woman presents to the Emergency Department with a sudden-onset blurring of vision in both eyes as well as light sensitivity. She is a known type II diabetic with blood sugars well maintained with medication.
On examination, her temperature is 36.8 oC, while her blood pressure (BP) is 180/110 mmHg. Her pulse is 70 beats per minute. Her respiratory rate is 18 breaths per minute, and her oxygen saturations are 98% on room air.
On dilated fundoscopy, both optic discs are swollen with widespread flame-shaped haemorrhages and cotton-wool spots.
What is the most appropriate first-line management of this condition?Your Answer: Intravenous (IV) labetalol
Explanation:Misconceptions about Treatment for Hypertensive Retinopathy
Hypertensive retinopathy is a condition that occurs when high blood pressure damages the blood vessels in the retina. However, there are several misconceptions about the treatment for this condition.
Firstly, in a hypertensive emergency with retinopathy, it is important to lower blood pressure slowly to avoid brain damage. Intravenous labetalol is a suitable medication for this purpose, with the aim of reducing diastolic blood pressure to 100 mmHg or reducing it by 20-25 mmHg per day, whichever is less.
Secondly, oral calcium channel blockers like amlodipine are not useful in an acute setting of hypertensive emergency. They are not effective in treating hypertensive retinopathy.
Thirdly, intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection is not a treatment for hypertensive retinopathy. It is used to treat wet age-related macular degeneration.
Fourthly, pan-retinal photocoagulation or any laser treatment for the eye is not a treatment for hypertensive retinopathy. It is a treatment for proliferative diabetic retinopathy.
Lastly, sublingual glyceryl trinitrate (GTN) spray is not a suitable treatment for hypertensive retinopathy. It is typically used in patients with angina and acute coronary syndrome.
In conclusion, it is important to understand the appropriate treatments for hypertensive retinopathy to avoid misconceptions and ensure proper care for patients.
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This question is part of the following fields:
- Ophthalmology
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Question 9
Correct
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In people aged 45-64, what is the most frequent cause of blindness? Choose ONE option from the list provided.
Your Answer: Diabetic retinopathy
Explanation:Common Eye Conditions: Causes and Prevalence
Diabetes can lead to various ophthalmic complications, including glaucoma, cataracts, and neuropathies, but the most common and potentially blinding is diabetic retinopathy. This condition accounts for 12% of all new cases of blindness in developed countries and is the leading cause of new blindness in people aged 25-64 years. Glaucoma, a group of eye diseases that damage the optic nerve, is more prevalent in the aging population, with up to 15% affected by the seventh decade of life. Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world, with non-exudative (dry) AMD comprising more than 90% of patients diagnosed with AMD. Optic atrophy, a sign of many disease processes, can cause changes in the color and structure of the optic disc associated with variable degrees of visual dysfunction. Finally, corneal abrasion, caused by a disruption in the integrity of the corneal epithelium or physical external forces, is the most common eye injury. While most people recover fully from minor corneal abrasions, deeper scratches can cause long-term vision problems if not treated properly.
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This question is part of the following fields:
- Ophthalmology
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Question 10
Incorrect
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A 35-year-old man presents with an acute onset of pain and blurred vision of his right eye. On examination, there is conjunctival injection and dendritic ulceration seen on his cornea.
Which of the following is the most likely diagnosis?
Your Answer: Trachoma
Correct Answer: Herpes simplex virus keratitis
Explanation:Differential diagnosis of a patient with unilateral eye symptoms
Herpes simplex virus keratitis and Candida endophthalmitis are two potential causes of unilateral eye symptoms, but other conditions should also be considered. A foreign body may cause corneal ulceration and blurred vision, but there is no evidence of its presence in the scenario. Trachoma is unlikely in a developed country, while glaucoma typically presents with bilateral symptoms or acute angle-closure in a minority of cases. A thorough history, physical examination, and appropriate tests can help to establish the correct diagnosis and guide treatment.
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This question is part of the following fields:
- Ophthalmology
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