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Question 1
Incorrect
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A 40-year-old male visits his family physician with the complaint of a high-grade fever for the past five days. A complete blood count report shows the presence of neutrophilia. Which one of the following facts regarding neutrophilia is accurate?
Your Answer: It is defined as a neutrophil count of > 5.0 X 10 9 /l
Correct Answer: It can be caused by eclampsia
Explanation:A total neutrophil count of greater than 7.5 x 109/L is called neutrophilia. Typhoid fever usually causes leukopenia or neutropenia. Both localised and generalised bacterial infections can cause neutrophilia. Metabolic disorders such as – gout- eclampsia- uraemia can also cause neutrophilia. Acute neutrophilia, in which immature neutrophils can be seen, is referred to as a left shift and can be seen in conditions such as appendicitis.
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This question is part of the following fields:
- Haematology
- Pathology
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Question 2
Correct
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A 28-year-old female patient with a history of hypothyroidism arrives at the Emergency Department after taking 30 of her 200 mcg levothyroxine tablets. She tells you she's 'tired of life' and 'can't take it any longer.' She is currently asymptomatic, and her findings are all within normal limits.What is the minimum amount of levothyroxine that must be taken before thyrotoxicosis symptoms appear?
Your Answer: >10 mg
Explanation:An overdose of levothyroxine can happen by accident or on purpose. Intentional overdosing is sometimes done to lose weight, but it can also happen in patients who are suicidal. The development of thyrotoxicosis, which can lead to excited sympathetic activity and high metabolism syndrome, is the main source of concern. The time between ingestion and the emergence of clinical features associated with an overdose is often quite long.After a levothyroxine overdose, the majority of patients are asymptomatic. Symptoms and signs are usually only seen in patients who have taken more than 10 mg of levothyroxine in total.The following are the most commonly seen clinical features in patients developing clinical features:TremorAgitationSweatingInsomniaHeadacheIncreased body temperatureIncreased blood pressureDiarrhoea and vomitingLess common clinical features associated with levothyroxine overdose include:SeizuresAcute psychosisThyroid stormTachycardiaArrhythmiasComaThe continued absorption of the ingested levothyroxine causes a progressive rise in both total serum T4 and total serum T3 levels in the first 24 hours after an overdose. However, in some cases, the biochemical picture is completely normal. Thyroid function tests are not always recommended after a thyroxine overdose. Although elevated thyroxine levels are common, they have little clinical significance and have no impact on treatment. Following a levothyroxine overdose, the following biochemical features are common:T4 and T3 levels in the blood are elevated.Free T4 and Free T3 levels are higher.TSH levels in the blood are low.If the patient is cooperative and more than 10 mg of levothyroxine has been consumed, activated charcoal can be given (i.e., likely to become symptomatic)Within an hour of ingestion, the patient presents.The treatment is mostly supportive and aimed at managing the sympathomimetic symptoms that come with levothyroxine overdose. If beta blockers aren’t an option, try propranolol 10-40 mg PO 6 hours or diltiazem 60-180 mg 8 hours.
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This question is part of the following fields:
- Endocrine Pharmacology
- Pharmacology
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Question 3
Incorrect
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When calculating the ventilation over perfusion ratio of a male patient, you should remember the ideal V/Q ratio for this patient to compare with his results. What is the approximate ventilation value for a healthy male patient?
Your Answer: 2.5 L/min
Correct Answer: 5 L/min
Explanation:The ventilation/perfusion ratio (V/Q ratio) is a ratio used to assess the efficiency and adequacy of the matching ventilation and perfusion. The ideal V/Q ratio is 1. In an average healthy male, the ventilation value is approximately 5 L/min and the perfusion value is approximately 5 L/min. Any mismatch between ventilation and perfusion will be evident in the V/Q ratio. If perfusion is normal but ventilation is reduced, the V/Q ratio will be less than 1, whereas if ventilation is normal but perfusion is reduced, the V/Q ratio will be greater than 1. If the alveoli were ventilated but not perfused at all, then the V/Q ratio would be infinity.
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This question is part of the following fields:
- Physiology
- Respiratory Physiology
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Question 4
Incorrect
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Glomerular filtration rate can be calculated using any substance that:
Your Answer: is freely filtered and completely reabsorbed by the nephron
Correct Answer: is freely filtered and neither reabsorbed nor secreted by the nephron
Explanation:Clearance of a substance can provide an accurate estimate of the glomerular filtration rate (GFR) provided that the substance is:freely filterednot reabsorbed in the nephronnot secreted in the nephronnot synthesised or metabolised by the kidney
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This question is part of the following fields:
- Physiology
- Renal
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Question 5
Correct
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Clostridium difficile primarily causes which of the following infectious diseases:
Your Answer: Pseudomembranous colitis
Explanation:Clostridium difficile causes pseudomembranous colitis, an acute inflammatory diarrhoeal disease and an important cause of morbidity and mortality in hospitals. Gas gangrene is primarily caused by Clostridium perfringens. Tetanus is caused by Clostridium tetani. Toxic shock syndrome may be caused by Staphylococcus aureus or Streptococcus pyogenes. Necrotising fasciitis is most commonly caused by Streptococcus pyogenes but has a multitude of causes.
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This question is part of the following fields:
- Microbiology
- Pathogens
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Question 6
Correct
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Which of the following clinical features is a feature of a chronic extravascular haemolytic anaemia:
Your Answer: Gallstones
Explanation:Clinical features of haemolytic anaemia include:AnaemiaJaundice (caused by unconjugated bilirubin in plasma, bilirubin is absent from urine)Pigment gallstonesSplenomegalyAnkle ulcersExpansion of marrow with, in children, bone expansion e.g. frontal bossing in beta-thalassaemia majorAplastic crisis caused by parvovirus
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This question is part of the following fields:
- Haematology
- Pathology
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Question 7
Incorrect
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Which of the following antibiotics is the first line of treatment for a patient who has been diagnosed with chlamydia infection?
Your Answer: Ceftriaxone
Correct Answer: Azithromycin
Explanation:The Centres for Disease Control and Prevention (CDC) recommends azithromycin, a single 1 g dose, and doxycycline, 100 mg bd for 7 days, as first-line medications for chlamydial infection treatment. Second-line medications (such as erythromycin, penicillins, and sulfamethoxazole) are less effective and have more side effects
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This question is part of the following fields:
- Microbiology
- Pathogens
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Question 8
Correct
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A 29 year old patient with known inflammatory bowel disease presents to ED with surgical complications following his recent ileocaecal resection. Removal of the terminal ileum may result in the malabsorption of which of the following:
Your Answer: Vitamin B12
Explanation:On ingestion, vitamin B12 is bound to R protein found in saliva and gastric secretions, which protects it from digestion in the stomach. Intrinsic factor is secreted by gastric parietal cells. Receptors for the IF-B12 complex are present in the membrane of epithelial cells of the terminal ileum, which bind the complex and allow uptake of vitamin B12 across the apical membrane by endocytosis. Vitamin B12 is then transported across the basal membrane into the portal blood where it is bound to transcobalamin II and processed by the liver. In pernicious anaemia, there are autoantibodies against gastric parietal cells and intrinsic factor, resulting in vitamin B12 deficiency anaemia.
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This question is part of the following fields:
- Gastrointestinal
- Physiology
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Question 9
Incorrect
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The functional residual capacity (FRC) will be decreased in which of the following:
Your Answer: Aging
Correct Answer: Pulmonary fibrosis
Explanation:Factors decreasing FRC:Restrictive ventilatory defects e.g. pulmonary fibrosisPosture – lying supineIncreased intra-abdominal pressure (e.g. obesity, pregnancy, ascites)Reduced muscle tone of diaphragm e.g. muscle relaxants in anaesthesia, neuromuscular disease
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This question is part of the following fields:
- Physiology
- Respiratory
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Question 10
Incorrect
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A 25-year-old athlete suffers an injury to the nerve that innervates the gluteus minimus muscle.Which of the following nerves innervates the gluteus minimus muscle?
Your Answer:
Correct Answer: Superior gluteal nerve
Explanation:Gluteus minimus is the smallest muscle of the glutei. It is located just beneath the gluteus medius muscle. Gluteus minimus predominantly acts as a hip stabilizer and abductor of the hip. The superior gluteal nerve innervates the gluteus minimus.
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This question is part of the following fields:
- Anatomy
- Lower Limb
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Question 11
Incorrect
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Which of the following best describes the correct administration of adrenaline for a shockable rhythm in adult advanced life support?
Your Answer:
Correct Answer: Give 1 mg of adrenaline after the third shock and every 3 - 5 minutes thereafter
Explanation:The correct administration of IV adrenaline 1 mg (10 mL of 1:10,000 solution) is that it should be given after 3 shocks and every 3 – 5 minutes/after alternate shocks thereafter.
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This question is part of the following fields:
- Cardiovascular
- Pharmacology
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Question 12
Incorrect
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A 67-year-old woman arrives at the Emergency Department with chest pain. Flecainide is one of the medications she is taking.Which of the following statements about flecainide mechanism of action is correct?
Your Answer:
Correct Answer: Blocks Na+ channels in the heart
Explanation:Flecainide is an antiarrhythmic drug of class Ic that works by blocking the Nav1.5 sodium channel in the heart, prolonging the cardiac action potential and slowing cardiac impulse conduction. It has a significant impact on accessory pathway conduction, particularly retrograde conduction, and significantly reduces ventricular ectopic foci.Many different arrhythmias can be treated with flecainide, including:Pre-excitation syndromes (e.g. Wolff-Parkinson-White)Acute atrial arrhythmiasVentricular arrhythmiasChronic neuropathic painThe use of flecainide is contraindicated in the following situations:Abnormal left ventricular functionAtrial conduction defects (unless pacing rescue available)Bundle branch block (unless pacing rescue available)Distal block (unless pacing rescue available)Haemodynamically significant valvular heart diseaseHeart failureHistory of myocardial infarctionLong-standing atrial fibrillation where conversion to sinus rhythm not attemptedSecond-degree or greater AV block (unless pacing rescue available)Sinus node dysfunction (unless pacing rescue available)Flecainide should only be used in people who don’t have a structural heart problem. The CAST trial found a significant increase in sudden cardiac death and all-cause mortality in patients with an ejection fraction of less than 40% after a myocardial infarction, where it tended to be pro-arrhythmic.Anti-arrhythmic drugs have a limited and ineffective role in the treatment of atrial flutter. It’s important to keep in mind that flecainide shouldn’t be used by itself to treat atrial flutter. When used alone, there is a risk of inducing 1:1 atrioventricular conduction, which results in an increase in ventricular rate that is paradoxical. As a result, it should be used in conjunction with a beta-blocker or a calcium channel blocker with a rate-limiting effect.
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This question is part of the following fields:
- Cardiovascular Pharmacology
- Pharmacology
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Question 13
Incorrect
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A patient with history of weight loss and diarrhoea was found out to have Giardia lamblia in her stool since returning from a holiday to Nepal.Which of the following statements is considered true regarding the life cycle of Giardia lamblia?
Your Answer:
Correct Answer: Trophozoites attach to the intestinal wall via a specialised sucking disc
Explanation:Cysts are resistant forms and are responsible for transmission of giardiasis. Both cysts and trophozoites can be found in the faeces (diagnostic stages). The cysts are hardy and can survive several months in cold water. Infection occurs by the ingestion of cysts in contaminated water, food, or by the faecal-oral route (hands or fomites). In the small intestine, excystation releases trophozoites (each cyst produces two trophozoites).Trophozoites multiply by longitudinal binary fission, remaining in the lumen of the proximal small bowel where they can be free or attached to the mucosa by a ventral sucking disk.Encystation occurs as the parasites transit toward the colon. The cyst is the stage found most commonly in non diarrheal faeces.Because the cysts are infectious when passed in the stool or shortly afterward, person-to-person transmission is possible. While animals are infected with Giardia, their importance as a reservoir is unclear.
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This question is part of the following fields:
- Microbiology
- Principles Of Microbiology
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Question 14
Incorrect
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Cystic fibrosis patients have a weakened lung surfactant system. Which of the following cell types is in charge of surfactant secretion?
Your Answer:
Correct Answer: Type II pneumocytes
Explanation:Alveolar type II cells are responsible for four primary functions: surfactant synthesis and secretion, xenobiotic metabolism, water transepithelial transport, and alveolar epithelium regeneration following lung injury.
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This question is part of the following fields:
- Physiology
- Respiratory
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Question 15
Incorrect
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A patient who is a known case of rheumatoid arthritis presents to the clinic as his grandson was recently diagnosed with chickenpox. His grandson spent the weekend with her, and he was in close contact with him. He takes 50 mg of prednisolone once daily and has been for the past six months. There is no history of chickenpox.Out of the following, which is TRUE regarding the next plan of action for her care?
Your Answer:
Correct Answer: She should receive prophylactic varicella-zoster Immunoglobulin (VZIG)
Explanation:Varicella-zoster immunoglobulin (VZIG) is indicated for post exposure prevention and treatment of varicella. It is recommended as prophylaxis for high-risk patients with no known immunity (i.e. no known previous chickenpox) who have had a significant exposure to varicella-zoster (considered >4 hours close contact).The high-risk groups are:1. Neonates2. Pregnant women3. The immunocompromised (e.g. cancer, immunosuppressive therapies)4. Those on high dose steroids (children on more than 2 mg/kg/day for more than 14 days, or adults on 40 mg/day for more than a week)This patient is at high risk of developing adrenal insufficiency and may need a temporary increase in her steroid dose during infection or stress. It would be inappropriate to stop or wean down her dose of prednisolone and can cause side effects.Since he is on steroids without immunity for chickenpox, he is at risk of developing severe varicella infection, with possible complications including pneumonia, hepatitis and DIC. If he develops a varicella infection, he will need to be admitted and require a specialist review and intravenous Acyclovir.
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This question is part of the following fields:
- Immunological Products & Vaccines
- Pharmacology
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Question 16
Incorrect
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As part of his angina treatment, a 68-year-old man is prescribed a beta blocker. He starts having nightmares and has trouble sleeping soon after starting the beta-blocker.Which of the beta blockers listed below is the most likely to be in his system?
Your Answer:
Correct Answer: Propranolol
Explanation:The beta-adrenoceptors in the heart, peripheral vasculature, bronchi, pancreas, and liver are blocked by beta-adrenoceptor blocking drugs (beta blockers).Beta blockers come in a wide range of strengths, with the choice largely determined by the disease being treated and the patient’s unique circumstances. The intrinsic sympathomimetic activity, lipid solubility, duration of action, and cardioselectivity of beta blockers all differ.Some beta blockers are lipid (lipophilic) soluble, while others are water soluble (hydrophilic). Drugs that are more lipid-soluble are absorbed faster from the gut, undergo more first-pass metabolism, and are eliminated faster. They’re also more likely to get into the brain and cause central effects like insomnia and nightmares. Propranolol, pindolol, labetalol, and metoprolol are examples of lipid-soluble beta blockers. Beta blockers that are water-soluble are less likely to enter the brain and are more resistant to first-pass metabolism. They are excreted by the kidneys, and in renal impairment, dosage reduction is frequently required. Atenolol, nadolol, celiprolol, and sotalol are examples of water-soluble beta blockers.
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This question is part of the following fields:
- Cardiovascular Pharmacology
- Pharmacology
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Question 17
Incorrect
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A 32 year old woman presents with episodes of flushing, headaches and palpitations. On examination her blood pressure is significantly elevated. Which of the following is the most likely diagnosis:
Your Answer:
Correct Answer: Pheochromocytoma
Explanation:Phaeochromocytomas are catecholamine-secreting tumours which occur in about 0.1% of patients with hypertension. In about 90% of cases they arise from the adrenal medulla. The remaining 10%, which arise from extra-adrenal chromaffin tissue, are termed paragangliomas. Common presenting symptoms include one or more of headache, sweating, pallor and palpitations. Less commonly, patients describe anxiety, panic attacks and pyrexia. Hypertension, whether sustained or episodic, is present in at least 90% of patients. Left untreated phaeochromocytoma can occasionally lead to hypertensive crisis, encephalopathy, hyperglycaemia, pulmonary oedema, cardiac arrhythmias, or even death.
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This question is part of the following fields:
- Endocrine
- Physiology
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Question 18
Incorrect
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The pathophysiology of Addison's disease is as follows:
Your Answer:
Correct Answer: Adrenocortical insufficiency
Explanation:Primary adrenal insufficiency, also known as Addison’s disease, occurs when the adrenal glands cannot produce an adequate amount of hormones despite a normal or increased corticotropin (ACTH) level.
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This question is part of the following fields:
- Endocrine
- Physiology
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Question 19
Incorrect
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A 19-year-old with a longstanding history of asthma presents to the ED with worsening symptoms of cough and wheeze and a peak expiratory flow rate (PEFR) measurement is taken.Which statement concerning PEFR is true?
Your Answer:
Correct Answer: PEFR is dependent upon the patient's height
Explanation:The maximum flow rate generated during a forceful exhalation, after maximal inspiration is the peak expiratory flow rate (PEFR).PEFR is dependent upon initial lung volume. It is, therefore, dependant on patient’s age, sex and height.PEFR is dependent on voluntary effort and muscular strength of the patient.PEFR is decreased with increasing airway resistance, e.g. in asthma, and it correlates well with the forced expiratory volume in one second (FEV1) value measured in spirometry. This correlation decreases in patients with asthma as airflow decreases.
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This question is part of the following fields:
- Physiology
- Respiratory Physiology
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Question 20
Incorrect
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Lidocaine's mechanism of action as a local aesthetic is as follows:
Your Answer:
Correct Answer: Blocks influx of Na+ through voltage-gated Na+ channels
Explanation:Local anaesthetics prevent generation/conduction of nerve impulses by reducing sodium permeability and increasing action potential threshold; inhibits depolarization, which results in blockade of conduction
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This question is part of the following fields:
- Anaesthesia
- Pharmacology
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Question 21
Incorrect
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All of the following statement are correct regarding endothelium derived nitric oxide except:
Your Answer:
Correct Answer: Nitric oxide production is inhibited by local mediators such as bradykinin, histamine and serotonin.
Explanation:Factors that elevate intracellular Ca2+ increase nitric oxide (NO) production by the endothelium included local mediators such as histamine and serotonin, bradykinin, and some neurotransmitters like substance P. NO production is also stimulated by increased flow (shear stress) and additionally activates prostacyclin synthesis. As a result of basal production of NO, there is continuous modulation of vascular resistance and as a result, there is increased production of nitric oxide acts which causes vasodilation. Platelet activation and thrombosis are inhibited by nitric oxide.
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This question is part of the following fields:
- Cardiovascular
- Physiology
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Question 22
Incorrect
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Which of the following ligaments supports the head of the talus?
Your Answer:
Correct Answer: Spring ligament
Explanation:The spring-ligament complex is a significant medial arch stabilizer. The two important functions of this ligament include promoting the stability of the talonavicular joint by acting as a support for the talus head and by acting as a static support to maintain the medial longitudinal arch.
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This question is part of the following fields:
- Anatomy
- Lower Limb
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Question 23
Incorrect
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Diabetic ketoacidosis is characterised by which of the following:
Your Answer:
Correct Answer: Hyperglycaemia, ketonaemia and acidosis
Explanation:DKA is characterised by the biochemical triad:1. Hyperglycaemia (> 11 mmol/L)2. Ketonaemia (> 3 mmol/L)3. Acidosis (pH < 7.3 +/- HCO3 < 15 mmol/L)
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This question is part of the following fields:
- Endocrine
- Physiology
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Question 24
Incorrect
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Regarding Clostridium tetani, which of the following statements is CORRECT:
Your Answer:
Correct Answer: Infection is predominantly derived from animal faeces and soil.
Explanation:Clostridium tetaniis a Gram positive, rod shaped, obligate anaerobic bacterium.The incubation period is quoted as anywhere between 4-21 days and can occur after several months but symptoms usually occur within the first 7 days after exposure.Approximately 80% of patients develop generalised tetanus. The commonest presenting feature of generalised tetanus is trismus (lockjaw), occurring in approximately 75% of affected individuals. Other clinical features include:Facial spasms (risus sardonicus)Opisthotonus (characteristic body shape during spasms)Neck stiffnessDysphagiaCalf and pectoral muscle rigidityFeverHypertensionTachycardiaSpasms can occur frequently and last for several minutes, they can continue to occur for up to 4 weeks. Current mortality rates are between 10 and 15%.Tetanic spasms are caused by the exotoxin tetanospasmin. The effects of tetanolysin are not fully understood but it is not believed to have clinical significance.Localised tetanus is a rare form of the disease, occurring in around 1% of affected individuals. Patients have persistent contraction of muscles in the same anatomic area as the injury. It may precede generalised tetanus.
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This question is part of the following fields:
- Microbiology
- Pathogens
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Question 25
Incorrect
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One of your patients has been infected by an obligate pathogen and presents with features of this condition.Which of these is an example of an obligate pathogen?
Your Answer:
Correct Answer: Trepenoma pallidum
Explanation:Treponema pallidum is an obligate pathogen. Obligate pathogens are almost always associated with disease and usually cannot survive outside of the body for long periods of time. Examples include and HIV.Staphylococcus aureus and Bacteroides fragilis are conditional pathogens. These are pathogens that usually cause disease only if certain conditions are met.Pneumocystis jiroveci and Pseudomonas aeruginosa, are opportunistic pathogens. These are pathogens that can only cause disease in an immunocompromised host or under unusual circumstances.
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This question is part of the following fields:
- Microbiology
- Principles Of Microbiology
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Question 26
Incorrect
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Which of the following statements is true regarding the extensor pollicis longus?
Your Answer:
Correct Answer: It is innervated by the posterior interosseous nerve
Explanation:Extensor pollicis longus is part of the deep extensors of the forearm together with extensor pollicis brevis, abductor pollicis longus, extensor indicis and supinator muscles. It is located on the posterior aspect of forearm, extending from the middle third of the ulna, and adjacent interosseous membrane, to the distal phalanx of the thumb.Extensor digitorum is innervated by posterior interosseous nerve which is a continuation of a deep branch of radial nerve (root value C7 and C8).Extensor pollicis brevis receives its blood supply from the posterior interosseous artery and perforating branches of the anterior interosseous artery.The main action of extensor pollicis longus is extension of the thumb at the metacarpophalangeal and interphalangeal joints. Extension at the metacarpophalangeal joint occurs in synergy with extensor pollicis brevis muscle. When the thumb reaches the full extension or abduction, extensor pollicis longus can also assist in adduction of the thumb.
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This question is part of the following fields:
- Anatomy
- Upper Limb
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Question 27
Incorrect
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Normal human immunoglobulin is mostly used to protect against which of the following infectious diseases?
Your Answer:
Correct Answer: Measles and hepatitis A
Explanation:Immune globulin IM is indicated for prophylaxis following exposureto hepatitis A, to prevent or modify measles (rubeola) in a susceptible person exposed fewer than 6 days previously,for susceptible household contacts of measles patients,particularly contacts <1 year and pregnant women without evidence of immunity, and to modify rubella in exposed pregnant women who will not consider a therapeutic abortion.
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This question is part of the following fields:
- Immunoglobulins And Vaccines
- Pharmacology
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Question 28
Incorrect
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A 62-year-old woman presents with a 3-month history of lethargy and tiredness. She states that she has also felt very itchy, particularly after a hot bath and that she is often dizzy and sweaty. On examination she appears plethoric and you note the presence of splenomegaly. Her blood tests today show that her haemoglobin level is 16.9 g/dl.What is the most likely diagnosis in this case? Select ONE answer only.
Your Answer:
Correct Answer: Polycythaemia vera
Explanation:Polycythaemia vera (PCV), which is also referred to as polycythaemia rubra vera, is a clonal haematological malignancy in which the bone marrow produces too many red blood cells. It may also result in the overproduction of white blood cells and platelets. It is most commonly seen in the elderly and the mean age at diagnosis is 65-74 years.Patients can be completely asymptomatic and it is often discovered as an incidental finding on a routine blood count. Approximately 1/3 of patients present with symptoms due to thrombosis, of these 3/4 have arterial thrombosis and 1/4 venous thrombosis. Features include stroke, myocardial infarction, deep vein thrombosis and pulmonary embolism.The other clinical features of PCV include:Plethoric appearanceLethargy and tirednessSplenomegaly (common)Pruritis (in 40% – particularly after exposure to hot water)Headaches, dizziness and sweating (in 30%)Gouty arthritis (in 20%)Budd-Chiari syndrome (in 5-10%)Erythromyalgia (in 18.5 g/dl in men, 16.5 g/dl in womenElevated red cell mass > 25% above mean normal predicted valuePresence of JAK2 mutationMinor criteria:Bone marrow biopsy showing hypercellularity with prominent erythroid, granulocytic and megakaryocytic proliferationSerum erythropoietin level below normal rangeEndogenous erythroid colony formation in vitroThe main aim of treatment is to normalize the full blood count and prevent complications such as thrombosis. Venesection is the treatment of choice but hydroxyurea can also be used to help control thrombocytosis.
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This question is part of the following fields:
- Haematology
- Pathology
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Question 29
Incorrect
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A 60-year-old man with trauma to his cervical spine suffers from damage to the ansa cervicalis, resulting to paresis of his infrahyoid muscles.All of the following are considered infrahyoid muscles, except:
Your Answer:
Correct Answer: Mylohyoid
Explanation:Infrahyoid muscles are also known as “strap muscles” which connect the hyoid, sternum, clavicle and scapula. They are located below the hyoid bone on the anterolateral surface of the thyroid gland and are involved in movements of the hyoid bone and thyroid cartilage during vocalization, swallowing and mastication. They are composed of four paired muscles, organized into two layers.Superficial layer consists of the sternohyoid and omohyoidDeep layer consists of the sternothyroid and thyrohyoid.
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This question is part of the following fields:
- Anatomy
- Head And Neck
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Question 30
Incorrect
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The patient is a 61-year-old man with severe central chest pain. An acute myocardial infarction is revealed by his ECG. Clopidogrel is one of the medications he takes as part of his treatment.Clopidogrel's direct mechanism of action is which of the following?
Your Answer:
Correct Answer: Inhibition of platelet ADP receptors
Explanation:Clopidogrel, a thienopyridine derivative, prevents platelet aggregation and cross-linking by the protein fibrin by inhibiting the ADP receptor on platelet cell membranes (inhibits binding of ADP to its platelet receptor (P2Y12 ADP-receptor).
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This question is part of the following fields:
- Cardiovascular Pharmacology
- Pharmacology
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