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  • Question 1 - A 50-year-old female comes to the doctor's office complaining of progressive paraesthesia in...

    Incorrect

    • A 50-year-old female comes to the doctor's office complaining of progressive paraesthesia in her fingers, toes, and peri-oral area for the past two weeks. She also experiences muscle cramps and spasms. The patient had a thyroidectomy for Graves' disease recently but has no other health issues or drug allergies. What can be expected from this patient's ECG results, considering the probable diagnosis?

      Your Answer: T wave inversion, QTc prolongation and visible U waves

      Correct Answer: Isolated QTc elongation

      Explanation:

      Following thyroid surgery, a patient is experiencing paraesthesia, cramps, and spasms, which are likely due to hypocalcemia resulting from damage to the parathyroid glands. The most common ECG change associated with this condition is isolated QTc elongation, while dysrhythmias are rare. Alternating QRS amplitude is not associated with this condition and is instead linked to pericardial effusion. Isolated QTc shortening is also incorrect as it is typically associated with hypercalcemia, which can be caused by hyperparathyroidism and malignancy. The combination of T wave inversion, QTc prolongation, and visible U waves is associated with hypokalemia, which can be caused by vomiting, thiazide use, and Cushing’s syndrome. Similarly, the combination of tall, peaked T waves, QTc shortening, and ST-segment depression is associated with hyperkalemia, which can be caused by Addison’s disease, rhabdomyolysis, acute kidney injury, and potassium-sparing diuretics.

      Complications of Thyroid Surgery: An Overview

      Thyroid surgery is a common procedure that involves the removal of all or part of the thyroid gland. While the surgery is generally safe, there are potential complications that can arise. These complications can be anatomical, such as damage to the recurrent laryngeal nerve, which can result in voice changes or difficulty swallowing. Bleeding is another potential complication, which can be particularly dangerous in the confined space of the neck and can lead to respiratory problems due to swelling. Additionally, damage to the parathyroid glands, which are located near the thyroid, can result in hypocalcaemia, a condition in which the body has low levels of calcium. It is important for patients to be aware of these potential complications and to discuss them with their healthcare provider before undergoing thyroid surgery.

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  • Question 2 - A 75-year-old man complains of persistent ringing in his left ear for the...

    Correct

    • A 75-year-old man complains of persistent ringing in his left ear for the past 4 months. He has also noticed a decline in hearing from his left ear over the past 2 weeks. During the examination, Rinne's test reveals that air conduction is louder than bone conduction in the left ear, and Weber's test shows lateralisation to the right ear. Which of the following conditions is likely to present with unilateral tinnitus and hearing loss?

      Your Answer: Acoustic neuroma

      Explanation:

      The traditional presentation of vestibular schwannoma involves a blend of symptoms such as vertigo, hearing impairment, tinnitus, and a missing corneal reflex.

      An acoustic neuroma is typically linked to one-sided tinnitus and hearing loss.

      Tinnitus and deafness are not commonly associated with multiple sclerosis (MS), which is a condition characterized by demyelination.

      Chronic otitis media is a persistent inflammation of the middle ear and mastoid cavity, which is marked by recurring otorrhoea and conductive hearing loss.

      Understanding Vestibular Schwannoma (Acoustic Neuroma)

      Vestibular schwannoma, also known as acoustic neuroma, is a type of brain tumor that accounts for 5% of intracranial tumors and 90% of cerebellopontine angle tumors. The condition is characterized by a combination of symptoms such as vertigo, hearing loss, tinnitus, and an absent corneal reflex. The affected cranial nerves can predict the features of the condition. For instance, cranial nerve VIII can cause vertigo, unilateral sensorineural hearing loss, and unilateral tinnitus. On the other hand, cranial nerve V can lead to an absent corneal reflex, while cranial nerve VII can cause facial palsy.

      Bilateral vestibular schwannomas are often seen in neurofibromatosis type 2. The diagnosis of vestibular schwannoma is made through an MRI of the cerebellopontine angle, and audiometry is also important since only 5% of patients have a normal audiogram.

      The management of vestibular schwannoma involves surgery, radiotherapy, or observation. The choice of treatment depends on the size and location of the tumor, the patient’s age and overall health, and the severity of symptoms. In conclusion, understanding vestibular schwannoma is crucial in managing the condition effectively.

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  • Question 3 - A 32-year-old man visits the clinic with a concern about experiencing frequent episodes...

    Correct

    • A 32-year-old man visits the clinic with a concern about experiencing frequent episodes of dizziness for the past four weeks, lasting about 1 hour each time. He has also noticed a ‘fullness sensation and ringing’ in his right ear.
      Select the SINGLE most probable diagnosis from the options below.

      Your Answer: Ménière’s disease

      Explanation:

      Understanding Common Causes of Vertigo: Ménière’s Disease, BPPV, Acoustic Neuroma, Vestibular Neuritis, and Cholesteatoma

      Vertigo is a common condition that can be caused by various factors. One of the most common causes is Ménière’s disease, which is characterized by a triad of symptoms including fluctuant hearing loss, vertigo, and tinnitus. Aural fullness may also be present. On the other hand, benign paroxysmal positional vertigo (BPPV) is induced by specific movements and is accompanied by nausea, light-headedness, and imbalance. Acoustic neuroma, on the other hand, presents with progressive ipsilateral tinnitus, sensorineural hearing loss, facial numbness, and giddiness. Vestibular neuritis, which follows a febrile illness, is characterized by sudden vertigo, vomiting, and prostration, while cholesteatoma tends to be asymptomatic in the early stages and is characterized by a foul-smelling discharge and conductive hearing loss. Management of vertigo includes self-care advice, medication, and referral to an ENT specialist to confirm the condition and exclude sinister causes.

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  • Question 4 - As a foundation doctor in general practice, you assess a thirty-five-year-old woman who...

    Correct

    • As a foundation doctor in general practice, you assess a thirty-five-year-old woman who presents with complaints of dizziness. She reports that the symptoms worsen when she rolls over in bed and are accompanied by nausea. She denies any prior episodes, aural fullness, or nystagmus. What diagnostic measures could be taken to confirm the diagnosis?

      Your Answer: Dix–Hallpike manoeuvre

      Explanation:

      The Dix-Hallpike test involves quickly moving the patient to a supine position with their neck extended to determine if they experience symptoms of benign paroxysmal positional vertigo. A positive result can confirm the diagnosis. Based on the symptoms, it is likely that this patient has this condition.

      Understanding Benign Paroxysmal Positional Vertigo

      Benign paroxysmal positional vertigo (BPPV) is a common condition that causes sudden dizziness and vertigo triggered by changes in head position. It typically affects individuals over the age of 55 and is less common in younger patients. Symptoms include vertigo triggered by movements such as rolling over in bed or looking upwards, and may be accompanied by nausea. Each episode usually lasts between 10-20 seconds and can be diagnosed through a positive Dix-Hallpike manoeuvre, which involves the patient experiencing vertigo and rotatory nystagmus.

      Fortunately, BPPV has a good prognosis and often resolves on its own within a few weeks to months. Treatment options include the Epley manoeuvre, which is successful in around 80% of cases, and vestibular rehabilitation exercises such as the Brandt-Daroff exercises. While medication such as Betahistine may be prescribed, it tends to have limited value. However, it is important to note that around half of people with BPPV will experience a recurrence of symptoms 3-5 years after their initial diagnosis.

      Overall, understanding BPPV and its symptoms can help individuals seek appropriate treatment and manage their condition effectively.

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  • Question 5 - A 35-year-old woman presents to the Emergency Department with a gradual decrease in...

    Correct

    • A 35-year-old woman presents to the Emergency Department with a gradual decrease in the hearing from her right ear. On further questioning, she reports that occasionally she hears a buzzing sound in this ear, but denies any episodes of dizziness or vomiting. Otoscopy of her right ear only reveals a reddish tympanic membrane. Rinne’s test is negative on the right, Weber’s test lateralises to the right. Which of the following describes the best management option for this condition?

      Your Answer: Hearing aid

      Explanation:

      The best option for managing the patient’s unilateral conductive hearing loss, tinnitus, and pinkish tympanic membrane is either a hearing aid or stapedectomy. The tuning fork tests indicate left-sided conductive hearing loss, which is consistent with otosclerosis. This condition is characterized by the replacement of normal bone with vascular spongy bone, leading to progressive conductive hearing loss due to stapes fixation at the oval window. Amoxicillin, betahistine and vestibular rehabilitation exercises, ear syringing, and prochlorperazine are not effective treatments for otosclerosis. Amoxicillin is used to manage acute otitis media, betahistine and vestibular rehabilitation exercises are used to prevent acute attacks in Ménière’s disease, ear syringing is used to remove impacted ear wax, and prochlorperazine is used to decrease dizziness in viral labyrinthitis.

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  • Question 6 - A 25-year-old woman presents to her General Practitioner with a complaint of difficulty...

    Correct

    • A 25-year-old woman presents to her General Practitioner with a complaint of difficulty sleeping due to a blocked nose at night. She uses inhalers regularly for wheezing during cold weather and experiences a cough at night. What is the most common complication of her underlying diagnosis that she may be experiencing?

      Your Answer: Nasal Polyps

      Explanation:

      Understanding Nasal Polyps and Associated Conditions

      Nasal polyps are a common condition that can cause a blocked nose, interrupting sleep and wheezing upon exertion. They are often associated with asthma, which is found along the atopic spectrum of diseases. Other conditions commonly associated with nasal polyps include allergic rhinitis and sinusitis.

      Allergic fungal sinusitis is another condition that can cause nasal polyps, but it is more commonly found in warmer climates and is not the most common cause in the United Kingdom. Paracetamol sensitivity is not associated with nasal polyps, but aspirin sensitivity is and can be part of Samter’s triad if the patient also has asthma.

      Chronic obstructive pulmonary disease (COPD) is not associated with nasal polyps, and it would be rare to see in a young patient unless there was underlying alpha-1 anti-trypsin disease. COPD is most commonly seen in long-term smokers and presents with symptoms such as shortness of breath and a longstanding cough.

      Diabetes mellitus is not associated with nasal polyps and would present with other symptoms such as polyuria, polydipsia, and fatigue. Understanding the conditions associated with nasal polyps can help with diagnosis and treatment.

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  • Question 7 - A 45-year-old businessman presents to the Emergency Department with his second episode of...

    Correct

    • A 45-year-old businessman presents to the Emergency Department with his second episode of epistaxis in a 24 hour period. On each occasion, the nosebleeds stopped with pressure applied just below the nasal bridge, but the most recent bleed went on for 30 minutes. He has hypertension, for which he takes medication regularly. He also admits to smoking a pack of cigarettes per day and drinking 10-15 units of alcohol each week. There is no history of trauma. He is worried about the problem affecting his work, as he has an important meeting the following day.
      On examination, he looks well and is not pale, and his blood pressure and pulse are within normal limits. He is peripherally well perfused. On inspection of the nasal vestibule, there are prominent blood vessels visible on the right side of the nasal septum, with a small amount of clotted blood also present.
      What is the most appropriate management plan for this patient?

      Your Answer: Cauterise the bleeding point using silver nitrate

      Explanation:

      Treatment Options for Epistaxis: From Simple First-Aid Measures to Invasive Procedures

      Epistaxis, or nosebleed, is a common condition that can be treated through simple first-aid measures. However, in cases of repeated or prolonged nosebleeds, more invasive treatment may be necessary. Here are some treatment options for epistaxis:

      Cauterization: If an anterior bleeding point is seen, cautery can be attempted. This is usually achieved by the application of a silver nitrate stick to the area for around 10 seconds after giving topical local anesthesia.

      Blood tests and investigations: Blood tests and other investigations are of little use, as an underlying cause is highly unlikely in a young and otherwise well patient.

      First-aid measures: Epistaxis is mainly treated through simple first-aid measures. It is important to reassure the patient that the problem is normally self-limiting.

      Nasal tampon: Bleeds that do not settle with cautery, or significant bleeds where a bleeding point cannot be seen, require the application of a nasal tampon and referral to ENT.

      Admission: This patient does not require admission. Blood tests are unlikely to be helpful, and she is haemodynamically stable.

      In summary, treatment options for epistaxis range from simple first-aid measures to invasive procedures. The choice of treatment depends on the severity and frequency of the nosebleeds.

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  • Question 8 - During a standard cranial nerve assessment, the subsequent results are noted: Rinne's test: Air...

    Correct

    • During a standard cranial nerve assessment, the subsequent results are noted: Rinne's test: Air conduction > bone conduction in both ears Weber's test: Localises to the right side What is the significance of these test outcomes?

      Your Answer: Left sensorineural deafness

      Explanation:

      If there is a sensorineural issue during Weber’s test, the sound will be perceived on the healthy side (right), suggesting a problem on the opposite side (left).

      Rinne’s and Weber’s Test for Differentiating Conductive and Sensorineural Deafness

      Rinne’s and Weber’s tests are two diagnostic tools used to differentiate between conductive and sensorineural deafness. Rinne’s test involves placing a tuning fork over the mastoid process until the sound is no longer heard, then repositioning it just over the external acoustic meatus. A positive test indicates that air conduction (AC) is better than bone conduction (BC), while a negative test suggests conductive deafness if BC is greater than AC.

      On the other hand, Weber’s test involves placing a tuning fork in the middle of the forehead equidistant from the patient’s ears and asking which side is loudest. In unilateral sensorineural deafness, sound is localized to the unaffected side, while in unilateral conductive deafness, sound is localized to the affected side.

      To interpret the results of Rinne’s and Weber’s tests, a normal result indicates that AC is greater than BC bilaterally, and the sound is midline in Weber’s test. Conductive hearing loss is indicated by BC being greater than AC in the affected ear, while AC is greater than BC in the unaffected ear, and the sound lateralizes to the affected ear in Weber’s test. Sensorineural hearing loss is indicated by AC being greater than BC bilaterally, and the sound lateralizes to the unaffected ear in Weber’s test.

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  • Question 9 - A 35-year-old man visits his GP complaining of nasal congestion, facial pain, a...

    Incorrect

    • A 35-year-old man visits his GP complaining of nasal congestion, facial pain, a runny nose, and a decreased sense of smell that has been ongoing for three months. He has a history of seasonal allergies. Upon palpation of the maxillofacial area, tenderness is noted. No visible nasal polyps are present.
      What are the primary symptoms of chronic sinusitis?

      Your Answer: Symptoms lasting greater than four weeks

      Correct Answer: Facial pain and/or pressure

      Explanation:

      Understanding the Symptoms of Chronic Rhinosinusitis

      Chronic rhinosinusitis is a condition characterized by inflammation of the sinuses that lasts for at least 12 weeks. To diagnose this condition, doctors look for specific symptoms that are indicative of chronic sinusitis. These symptoms include nasal obstruction, nasal discharge, facial pain and pressure, and loss of smell sensation.

      Facial pain and pressure are common symptoms of chronic sinusitis, and they are caused by congestion of the sinuses. Pain is typically felt over the maxillary, ethmoid, and frontal sinuses, which can be palpated by a doctor during an examination. Coughing is not a major symptom of chronic sinusitis, but it may be present in some patients and could indicate an underlying condition such as asthma or COPD.

      Nasal polyps are not a major symptom of chronic sinusitis, but they can be present in some individuals with this condition. The presence of nasal polyps indicates a variant of chronic sinusitis, which may require different management strategies.

      It is important to note that symptoms must last for at least 12 weeks without resolution before a diagnosis of chronic rhinosinusitis can be made. If symptoms last for less than 12 weeks, the criteria for chronic rhinosinusitis are not met. While patients may be experiencing chronic sinusitis before the 12-week mark, doctors must wait for this duration to confirm the diagnosis.

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  • Question 10 - Which of the following viruses is linked to nasopharyngeal carcinoma? ...

    Correct

    • Which of the following viruses is linked to nasopharyngeal carcinoma?

      Your Answer: Epstein-Barr virus

      Explanation:

      EBV is linked to the development of Burkitt’s lymphoma, Hodgkin’s lymphoma, and nasopharyngeal carcinoma.

      Conditions Associated with Epstein-Barr Virus

      Epstein-Barr virus (EBV) is linked to several conditions, including malignancies and non-malignant conditions. The malignancies associated with EBV infection include Burkitt’s lymphoma, Hodgkin’s lymphoma, nasopharyngeal carcinoma, and HIV-associated central nervous system lymphomas. Burkitt’s lymphoma is currently believed to be associated with both African and sporadic cases.

      Apart from malignancies, EBV infection is also associated with a non-malignant condition called hairy leukoplakia. This condition is characterized by white patches on the tongue and inside of the cheeks. It is often seen in people with weakened immune systems, such as those with HIV/AIDS.

      In summary, EBV infection is linked to several conditions, including both malignant and non-malignant ones. Understanding the association between EBV and these conditions is crucial for developing effective prevention and treatment strategies.

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