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Question 1
Correct
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A 6-year-old girl is playing with some small ball bearings. Regrettably, she inhales one. In which of the following lung regions is the ball expected to settle?
Your Answer: Right lower lobe
Explanation:Due to the angle of the right main bronchus from the trachea, small objects are more likely to get stuck in the most dependent part of the right lung. This makes the right lung the preferred location for most objects to enter.
Anatomy of the Lungs
The lungs are a pair of organs located in the chest cavity that play a vital role in respiration. The right lung is composed of three lobes, while the left lung has two lobes. The apex of both lungs is approximately 4 cm superior to the sternocostal joint of the first rib. The base of the lungs is in contact with the diaphragm, while the costal surface corresponds to the cavity of the chest. The mediastinal surface contacts the mediastinal pleura and has the cardiac impression. The hilum is a triangular depression above and behind the concavity, where the structures that form the root of the lung enter and leave the viscus. The right main bronchus is shorter, wider, and more vertical than the left main bronchus. The inferior borders of both lungs are at the 6th rib in the mid clavicular line, 8th rib in the mid axillary line, and 10th rib posteriorly. The pleura runs two ribs lower than the corresponding lung level. The bronchopulmonary segments of the lungs are divided into ten segments, each with a specific function.
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This question is part of the following fields:
- Respiratory System
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Question 2
Incorrect
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A 35-year-old man arrives at the emergency department following an assault with a baseball bat. He has significant swelling around his eye, which has caused him to lose vision in that eye. A CT scan reveals a fracture in the floor of the orbit. This type of fracture creates an unusual connection between the orbit and which of the following facial regions?
Your Answer: Sphenoid sinus
Correct Answer: Maxillary sinus
Explanation:The correct answer is the maxillary sinus, which is the largest of the paranasal air sinuses found in the maxillary bone below the orbit. Fractures of the orbit’s floor can lead to herniation of the orbital contents into the maxillary sinus. The ethmoidal air cells are smaller air cells in the ethmoid bone, separated from the orbit by a thin plate of bone called the lamina papyracea. Fractures of the medial wall of the orbit can lead to communication between the ethmoidal air cells and the orbit. The frontal sinuses are located in the frontal bones above the orbits and fractures of the roof of the orbit can lead to communication between the frontal sinus and orbit. The sphenoid sinuses are found in the sphenoid bone and are located in the posterior portion of the roof of the nasal cavity. The nasal cavity is located more medial and inferior than the orbits and is not adjacent to the orbit.
Paranasal Air Sinuses and Carotid Sinus
The paranasal air sinuses are air-filled spaces found in the bones of the skull. They are named after the bone in which they are located and all communicate with the nasal cavity. The four paired paranasal air sinuses are the frontal sinuses, maxillary sinuses, ethmoid air cells, and sphenoid sinuses. The frontal sinuses are located above each eye on the forehead, while the maxillary sinuses are the largest and found in the maxillary bone below the orbit. The ethmoidal air cells are a collection of smaller air cells located lateral to the anterior superior nasal cavity, while the sphenoid sinuses are found in the posterior portion of the roof of the nasal cavity.
On the other hand, the carotid sinus is not a paranasal air sinus. It is a dilatation of the internal carotid artery, located just beyond the bifurcation of the common carotid artery. It contains baroreceptors that enable it to detect changes in arterial pressure.
Overall, understanding the location and function of these sinuses and the carotid sinus is important in various medical procedures and conditions.
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This question is part of the following fields:
- Respiratory System
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Question 3
Incorrect
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An 87-year-old man with a history of interstitial lung disease is admitted with fever, productive cough, and difficulty breathing. His inflammatory markers are elevated, and a chest x-ray reveals focal patchy consolidation in the right lung. He requires oxygen supplementation as his oxygen saturation level is 87% on room air. What factor causes a decrease in haemoglobin's affinity for oxygen?
Your Answer: Decrease in temperature
Correct Answer: Increase in temperature
Explanation:What effect does pyrexia have on the oxygen dissociation curve?
Understanding the Oxygen Dissociation Curve
The oxygen dissociation curve is a graphical representation of the relationship between the percentage of saturated haemoglobin and the partial pressure of oxygen in the blood. It is not influenced by the concentration of haemoglobin. The curve can shift to the left or right, indicating changes in oxygen delivery to tissues. When the curve shifts to the left, there is increased saturation of haemoglobin with oxygen, resulting in decreased oxygen delivery to tissues. Conversely, when the curve shifts to the right, there is reduced saturation of haemoglobin with oxygen, leading to enhanced oxygen delivery to tissues.
The L rule is a helpful mnemonic to remember the factors that cause a shift to the left, resulting in lower oxygen delivery. These factors include low levels of hydrogen ions (alkali), low partial pressure of carbon dioxide, low levels of 2,3-diphosphoglycerate, and low temperature. On the other hand, the mnemonic ‘CADET, face Right!’ can be used to remember the factors that cause a shift to the right, leading to raised oxygen delivery. These factors include carbon dioxide, acid, 2,3-diphosphoglycerate, exercise, and temperature.
Understanding the oxygen dissociation curve is crucial in assessing the oxygen-carrying capacity of the blood and the delivery of oxygen to tissues. By knowing the factors that can shift the curve to the left or right, healthcare professionals can make informed decisions in managing patients with respiratory and cardiovascular diseases.
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This question is part of the following fields:
- Respiratory System
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Question 4
Correct
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A 25-year-old man who is an avid cyclist has been admitted to the hospital with a severe asthma attack. He is currently in the hospital for two days and is able to speak in complete sentences. His bedside oxygen saturation is at 98%, and he has a heart rate of 58 bpm, blood pressure of 110/68 mmHg, and a respiratory rate of 14 bpm. He is not experiencing any fever. Upon physical examination, there are no notable findings. The blood gas results show a PaO2 of 5.4 kPa (11.3-12.6), PaCO2 of 6.0 kPa (4.7-6.0), pH of 7.38 (7.36-7.44), and HCO3 of 27 mmol/L (20-28). What could be the possible explanation for these results?
Your Answer: Venous sample
Explanation:Suspecting Venous Blood Sample with Low PaO2 and Good Oxygen Saturation
A low PaO2 level accompanied by a good oxygen saturation reading may indicate that the blood sample was taken from a vein rather than an artery. This suspicion is further supported if the patient appears to be in good health. It is unlikely that a faulty pulse oximeter is the cause of the discrepancy in readings. Therefore, it is important to consider the possibility of a venous blood sample when interpreting these results. Proper identification of the type of blood sample is crucial in accurately diagnosing and treating the patient’s condition.
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This question is part of the following fields:
- Respiratory System
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Question 5
Correct
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As the pregnancy progresses, at what stage does the foetus typically begin producing surfactant?
A mother has been informed that she will have to deliver her baby prematurely due to complications in the pregnancy. To decrease the chances of neonatal distress syndrome, doctors have administered steroids to stimulate surfactant production in the foetus. They clarify that the foetus is already generating its own surfactant, and these steroids will enhance the process.Your Answer: Week 22
Explanation:Lung development in humans begins at week 4 with the formation of the respiratory diverticulum. By week 10, the lungs start to grow as tertiary bronchial buds form. Terminal bronchioles begin to form around week 18. The saccular stage of lung development, which marks the earliest viability for a human fetus, occurs at around 22-24 weeks when type 2 alveolar cells start producing surfactant. By week 30, the primary alveoli form as the mesenchyme surrounding the lungs becomes highly vascular.
The Importance of Pulmonary Surfactant in Breathing
Pulmonary surfactant is a substance composed of phospholipids, carbohydrates, and proteins that is released by type 2 pneumocytes. Its main component, dipalmitoyl phosphatidylcholine (DPPC), plays a crucial role in reducing alveolar surface tension. This substance is first detectable around 28 weeks and increases in concentration as the alveoli decrease in size. This helps prevent the alveoli from collapsing and reduces the muscular force needed to expand the lungs, ultimately decreasing the work of breathing. Additionally, pulmonary surfactant lowers the elastic recoil at low lung volumes, preventing the alveoli from collapsing at the end of each expiration. Overall, pulmonary surfactant is essential in maintaining proper lung function and preventing respiratory distress.
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This question is part of the following fields:
- Respiratory System
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Question 6
Incorrect
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A 10-year-old boy comes to your clinic with a complaint of ear pain that started last night and kept him awake. He missed school today because of the pain and reports muffled sounds on the affected side. During otoscopy, you observe a bulging tympanic membrane with visible fluid behind it, indicating a middle ear infection. Can you identify which nerves pass through the middle ear?
Your Answer: Vestibulocochlear nerve
Correct Answer: Chorda tympani
Explanation:The chorda tympani is the correct answer. It is a branch of the seventh cranial nerve, the facial nerve, and carries parasympathetic and taste fibers. It passes through the middle ear before exiting and joining with the lingual nerve to reach the tongue and salivary glands.
The vestibulocochlear nerve is the eighth cranial nerve and carries balance and hearing information.
The maxillary nerve is the second division of the fifth cranial nerve and carries sensation from the upper teeth, nasal cavity, and skin.
The mandibular nerve is the third division of the fifth cranial nerve and carries sensation from the lower teeth, tongue, mandible, and skin. It also carries motor fibers to certain muscles.
The glossopharyngeal nerve is the ninth cranial nerve and carries taste and sensation from the posterior one-third of the tongue, as well as sensation from various areas. It also carries motor and parasympathetic fibers.
The patient in the question has ear pain, likely due to otitis media, as evidenced by a bulging tympanic membrane and fluid level on otoscopy.
Anatomy of the Ear
The ear is divided into three distinct regions: the external ear, middle ear, and internal ear. The external ear consists of the auricle and external auditory meatus, which are innervated by the greater auricular nerve and auriculotemporal branch of the trigeminal nerve. The middle ear is the space between the tympanic membrane and cochlea, and is connected to the nasopharynx by the eustachian tube. The tympanic membrane is composed of three layers and is approximately 1 cm in diameter. The middle ear is innervated by the glossopharyngeal nerve. The ossicles, consisting of the malleus, incus, and stapes, transmit sound vibrations from the tympanic membrane to the inner ear. The internal ear contains the cochlea, which houses the organ of corti, the sense organ of hearing. The vestibule accommodates the utricule and saccule, which contain endolymph and are surrounded by perilymph. The semicircular canals, which share a common opening into the vestibule, lie at various angles to the petrous temporal bone.
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This question is part of the following fields:
- Respiratory System
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Question 7
Correct
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A 58-year-old man comes to the GP complaining of wheezing, coughing, and shortness of breath. He has a smoking history of 35 pack-years but has reduced his smoking recently.
The GP orders spirometry, which confirms a diagnosis of chronic obstructive pulmonary disease. The results also show an elevated functional residual capacity.
What is the method used to calculate this metric?Your Answer: Expiratory reserve volume + residual volume
Explanation:Understanding Lung Volumes in Respiratory Physiology
In respiratory physiology, lung volumes can be measured to determine the amount of air that moves in and out of the lungs during breathing. The diagram above shows the different lung volumes that can be measured.
Tidal volume (TV) refers to the amount of air that is inspired or expired with each breath at rest. In males, the TV is 500ml while in females, it is 350ml.
Inspiratory reserve volume (IRV) is the maximum volume of air that can be inspired at the end of a normal tidal inspiration. The inspiratory capacity is the sum of TV and IRV. On the other hand, expiratory reserve volume (ERV) is the maximum volume of air that can be expired at the end of a normal tidal expiration.
Residual volume (RV) is the volume of air that remains in the lungs after maximal expiration. It increases with age and can be calculated by subtracting ERV from FRC. Speaking of FRC, it is the volume in the lungs at the end-expiratory position and is equal to the sum of ERV and RV.
Vital capacity (VC) is the maximum volume of air that can be expired after a maximal inspiration. It decreases with age and can be calculated by adding inspiratory capacity and ERV. Lastly, total lung capacity (TLC) is the sum of vital capacity and residual volume.
Physiological dead space (VD) is calculated by multiplying tidal volume by the difference between arterial carbon dioxide pressure (PaCO2) and end-tidal carbon dioxide pressure (PeCO2) and then dividing the result by PaCO2.
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This question is part of the following fields:
- Respiratory System
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Question 8
Incorrect
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During a radical neck dissection, at what age would division of which of the following fascial layers expose the ansa cervicalis?
Your Answer: Carotid sheath
Correct Answer: Pretracheal fascia
Explanation:To access the ansa cervicalis, one must cut through the pretracheal fascia on the posterolateral side of the thyroid gland. This nerve is located in front of the carotid sheath. However, it should be noted that the pre vertebral fascia is situated further back and cannot be reached by dividing the investing layer of fascia.
The ansa cervicalis is a nerve that provides innervation to the sternohyoid, sternothyroid, and omohyoid muscles. It is composed of two roots: the superior root, which branches off from C1 and is located anterolateral to the carotid sheath, and the inferior root, which is derived from the C2 and C3 roots and passes posterolateral to the internal jugular vein. The inferior root enters the inferior aspect of the strap muscles, which are located in the neck, and should be divided in their upper half when exposing a large goitre. The ansa cervicalis is situated in front of the carotid sheath and is an important nerve for the proper functioning of the neck muscles.
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This question is part of the following fields:
- Respiratory System
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Question 9
Incorrect
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A 67-year-old man has been diagnosed with stage III lung cancer and is concerned about potential complications. What are the risks he may face?
Your Answer: Pulmonary fibrosis
Correct Answer: Pneumothorax
Explanation:Pneumothorax is more likely to occur in individuals with lung cancer.
Pneumothorax: Characteristics and Risk Factors
Pneumothorax is a medical condition characterized by the presence of air in the pleural cavity, which is the space between the lungs and the chest wall. This condition can occur spontaneously or as a result of trauma or medical procedures. There are several risk factors associated with pneumothorax, including pre-existing lung diseases such as COPD, asthma, cystic fibrosis, lung cancer, and Pneumocystis pneumonia. Connective tissue diseases like Marfan’s syndrome and rheumatoid arthritis can also increase the risk of pneumothorax. Ventilation, including non-invasive ventilation, can also be a risk factor.
Symptoms of pneumothorax tend to come on suddenly and can include dyspnoea, chest pain (often pleuritic), sweating, tachypnoea, and tachycardia. In some cases, catamenial pneumothorax can be the cause of spontaneous pneumothoraces occurring in menstruating women. This type of pneumothorax is thought to be caused by endometriosis within the thorax. Early diagnosis and treatment of pneumothorax are crucial to prevent complications and improve outcomes.
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This question is part of the following fields:
- Respiratory System
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Question 10
Incorrect
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A 67-year-old female smoker with a two-month history of worsening shortness of breath presents for evaluation. On examination, she appears comfortable at rest with a regular pulse of 72 bpm, respiratory rate of 16/min, and blood pressure of 128/82 mmHg. Physical findings include reduced expansion on the left lower zone, dullness to percussion over this area, and absent breath sounds over the left lower zone with bronchial breath sounds just above this region. What is the likely clinical diagnosis?
Your Answer: Pneumothorax
Correct Answer: Pleural effusion
Explanation:Pleural Effusion and its Investigation
Pleural effusion is a condition where there is an abnormal accumulation of fluid in the pleural space, which is the space between the lungs and the chest wall. This can be caused by various factors such as post-infection, carcinoma, or emboli. To determine the cause of the pleural effusion, a pleural tap is the most appropriate investigation. The sample obtained from the pleural tap is sent for cytology, protein concentration, and culture.
A normal pleural tap would have clear appearance, pH of 7.60-7.64, protein concentration of less than 2%, white blood cells count of less than 1000/mm³, glucose level similar to that of plasma, LDH level of less than 50% of plasma concentration, amylase level of 30-110 U/L, triglycerides level of less than 2 mmol/l, and cholesterol level of 3.5-6.5 mmol/l.
A transudative tap is associated with conditions such as congestive heart failure, liver cirrhosis, severe hypoalbuminemia, and nephrotic syndrome. On the other hand, an exudative tap is associated with malignancy, infection (such as empyema due to bacterial pneumonia), trauma, pulmonary infarction, and pulmonary embolism.
In summary, pleural effusion can be caused by various factors and a pleural tap is the most appropriate investigation to determine the cause. The results of the pleural tap can help differentiate between transudative and exudative effusions, which can provide important information for diagnosis and treatment.
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This question is part of the following fields:
- Respiratory System
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