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Question 1
Correct
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A 67-year-old woman visits her GP complaining of urinary incontinence. She experiences this symptom throughout the day and has noticed that her urine flow is weak when she does manage to go voluntarily. During the examination, the GP detects a distended bladder despite the patient having just urinated before the appointment. What is the probable diagnosis for this woman's condition?
Your Answer: Urinary overflow incontinence
Explanation:The patient, an elderly woman, is experiencing urinary incontinence as evidenced by the palpable bladder even after urination. While prostate problems are a common cause of urinary overflow incontinence, this is not applicable in this case as the patient is a woman. Other possible causes include nerve damage resulting in a neurogenic bladder, which can be a complication of diabetes, chronic alcoholism, or pelvic surgery. The absence of a sudden urge to urinate rules out urge incontinence, while overactive bladder syndrome, a type of urge incontinence, is characterized by incontinence, frequent urination, and nocturia, which are not present in this case. Stress incontinence, which is associated with increased intraabdominal pressure, is also not observed. Therefore, a diagnosis of mixed incontinence is not warranted.
Understanding Urinary Incontinence: Causes, Classification, and Management
Urinary incontinence (UI) is a common condition that affects around 4-5% of the population, with elderly females being more susceptible. Several risk factors contribute to UI, including advancing age, previous pregnancy and childbirth, high body mass index, hysterectomy, and family history. UI can be classified into different types, such as overactive bladder (OAB)/urge incontinence, stress incontinence, mixed incontinence, overflow incontinence, and functional incontinence.
Initial investigation of UI involves completing bladder diaries for at least three days, vaginal examination, urine dipstick and culture, and urodynamic studies. Management of UI depends on the predominant type of incontinence. For urge incontinence, bladder retraining and bladder stabilizing drugs such as antimuscarinics are recommended. For stress incontinence, pelvic floor muscle training and surgical procedures such as retropubic mid-urethral tape procedures may be offered. Duloxetine, a combined noradrenaline and serotonin reuptake inhibitor, may also be used as an alternative to surgery.
In summary, understanding the causes, classification, and management of UI is crucial in providing appropriate care for patients. Early diagnosis and intervention can significantly improve the quality of life for those affected by this condition.
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This question is part of the following fields:
- Urology
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Question 2
Correct
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You have organized a semen analysis for a 37-year-old man who has been experiencing difficulty in conceiving with his partner for the past year. The results are as follows:
- Semen volume 1.8 ml (1.5ml or more)
- pH 7.4 (7.2 or more)
- Sperm concentration 12 million per ml (15 million per ml or more)
- Total sperm number 21 million (39 million or more)
- Total motility 40% progressively motile (32% or more)
- Vitality 68% live spermatozoa (58% or more)
- Normal forms 5% (4% or more)
His partner is also undergoing investigations, and you plan on referring him to fertility services. What steps should be taken based on these semen analysis results?Your Answer: Repeat test in 3 months
Explanation:If a semen sample shows abnormal results, it is recommended to schedule a repeat test after 3 months to allow for the completion of the spermatozoa formation cycle. Immediate retesting should only be considered if there is a severe deficiency in spermatozoa, such as azoospermia or a sperm concentration of less than 5 million per ml. In this case, the man has mild oligozoospermia/oligospermia and a confirmatory test should be arranged after 3 months.
Understanding Semen Analysis
Semen analysis is a test that measures the quality and quantity of semen in a man’s ejaculate. To ensure accurate results, it is recommended that the sample be collected after a minimum of 3 days and a maximum of 5 days of abstinence. It is also important to deliver the sample to the lab within 1 hour of collection.
The normal semen results include a volume of more than 1.5 ml, a pH level of more than 7.2, a sperm concentration of more than 15 million per ml, morphology of more than 4% normal forms, motility of more than 32% progressive motility, and vitality of more than 58% live spermatozoa. However, it is important to note that different reference ranges may exist, and these values are based on the NICE 2013 guidelines.
Overall, semen analysis is an important tool in assessing male fertility and can provide valuable information for couples trying to conceive.
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This question is part of the following fields:
- Urology
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Question 3
Correct
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You are reviewing a physically fit 78 year old gentleman in the urology outpatient clinic. He initially presented to his GP with an episode of frank haematuria. Urinalysis revealed ongoing microscopic haematuria. Following referral to the urologist, a contrast MRI scan reveals a solitary low risk non-muscle invasive bladder cancer.
Which of the following would be the most appropriate treatment?Your Answer: Transurethral resection of bladder tumour (TURBT)
Explanation:Management Options for Low Risk Non-Muscle Invasive Bladder Tumours
When a patient is diagnosed with a low risk non-muscle invasive bladder tumour, the primary treatment option is surgical resection using the transurethral method. This procedure is likely to be curative, but a single dose of intravesical mitomycin C may be offered as adjunctive therapy. Routine follow-up and surveillance cystoscopies are necessary to monitor for recurrence.
A radical cystectomy and urostomy formation are reserved for patients with confirmed muscle invasive bladder tumours. Radiotherapy alone is only considered for those who are unfit for a radical cystectomy and have high risk or muscle invasive tumours. Palliative management is not appropriate for patients with curable tumours.
Intravesical bacillus Calmette-Guerin (BCG) is the treatment of choice for high-risk lesions, but it is not appropriate for low risk tumours. Therefore, surgical resection remains the primary management option for low risk non-muscle invasive bladder tumours.
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This question is part of the following fields:
- Urology
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Question 4
Correct
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You are asked to place a catheter in a pediatric patient for urinary retention. You select a 6-Fr catheter.
Which of the following is the most accurate description of the size of this catheter?Your Answer: The external circumference of the catheter is approximately 24mm
Explanation:Understanding Catheter Sizes: A Guide to the French Gauge System
Catheters are medical devices used to drain urine from the bladder when a patient is unable to do so naturally. The size of a catheter is an important factor in ensuring proper placement and function. The French gauge system is commonly used to describe catheter sizes, with the size in French units roughly equal to the circumference of the catheter in millimetres.
It is important to note that the French size only describes the external circumference of the catheter, not its length or internal diameter. A catheter that is too large can cause discomfort and irritation, while one that is too small can lead to kinking and leakage.
For male urethral catheterisation, a size 14-Fr or 16-Fr catheter is typically appropriate. Larger sizes may be recommended for patients with haematuria or clots. Paediatric sizes range from 3 to 14-Fr.
In summary, understanding the French gauge system is crucial in selecting the appropriate catheter size for each patient’s needs.
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This question is part of the following fields:
- Urology
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Question 5
Correct
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A 65-year-old patient is referred to the Outpatient Clinic with raised prostate-specific antigen (PSA), but a normal prostate on physical examination. He is later diagnosed with prostate cancer on biopsy.
What is the most common area of the prostate where this disease develops?Your Answer: The peripheral zone
Explanation:Anatomy of the Prostate Gland and its Relation to Prostate Cancer
The prostate gland is a small, walnut-shaped gland located in the male reproductive system. It is divided into several zones, each with its own unique characteristics and potential for developing prostate cancer.
The peripheral zone is the most common site for developing prostate carcinomas. It extends around the gland from the apex to the base and is located posterolaterally.
The central zone surrounds the ejaculatory duct apparatus and makes up the majority of the prostatic base.
The transition zone constitutes two small lobules that abut the prostatic urethra and is where benign prostatic hyperplasia (BPH) tends to originate. Carcinomas that originate in the transition zone have been suggested to be of lower malignant potential compared to those in the peripheral zone.
The anterior fibromuscular stroma is the most anterior portion of the gland and is formed by muscle cells intermingled with dense connective tissue. The chance of malignancy occurring in this area is low, but asymmetrical hypertrophy of the anterior fibromuscular stroma can mimic the presence of prostate cancer.
The posterior capsule is made of connective tissue and is usually not the primary origin of prostate cancer. The cancer usually arises in the peripheral zone and may then extend through the capsule as it progresses.
Understanding the anatomy of the prostate gland and its relation to prostate cancer can aid in early detection and treatment. Regular prostate exams and screenings are important for maintaining prostate health.
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This question is part of the following fields:
- Urology
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Question 6
Correct
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A 25-year-old man presents to the Emergency Department with a 4-hour history of sudden-onset pain in his left scrotum that makes walking difficult. On examination, his left testicle is firm and diffusely tender.
What is the most urgent management option?Your Answer: Scrotal exploration
Explanation:Diagnosis and Treatment of Testicular Torsion
Testicular torsion is a medical emergency that requires immediate attention. One of the main differential diagnoses to consider in a patient with scrotal pain is testicular torsion. If there is a high suspicion of torsion, emergency exploration surgery should not be delayed by investigations.
During scrotal exploration, the affected testicle is inspected for viability. If viable, detorsion and orchidopexy are performed. However, if the testicle is non-viable, it must be removed. The salvage rate for detorsion within 6 hours of symptom onset is >95%, but this drops to <10% after 24 hours. While antibiotics and analgesia are appropriate for epididymo-orchitis, ruling out testicular torsion is the priority. Urinalysis may be helpful in borderline cases, but an abnormal result does not exclude testicular torsion. Doppler ultrasound scan of the testes may also be useful, but if there is a high suspicion of torsion, scrotal exploration must not be delayed by investigations.
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This question is part of the following fields:
- Urology
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Question 7
Correct
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A male toddler, on physical examination at the age of 2, is noticed to have an abnormal opening of the urethra on to the ventral surface of the penis.
Which of the following is the most likely diagnosis?Your Answer: Hypospadias
Explanation:Common Congenital Penile Deformities and Conditions
Hypospadias, Cryptorchidism, Exstrophy, Epispadias, and Phimosis are all congenital penile deformities and conditions that affect newborn boys. Hypospadias is the most common, occurring in about 1 in every 150-300 boys. It is characterized by an abnormal opening of the urethral meatus on the ventral surface of the penis, ventral curvature of the penis, and a hooded foreskin. Cryptorchidism, on the other hand, is the failure of the testes to descend into the scrotal sac and is seen in 3% of all full-term newborn boys. Exstrophy is a rare condition where the bladder protrudes through a defect in the lower abdominal wall. Epispadias is defined as an abnormal opening of the urethra on the dorsal aspect of the penis, while Phimosis is a condition where the foreskin cannot be fully retracted over the glans of the penis. These conditions may have genetic components and can lead to complications such as infection, urinary tract obstruction, and other associated conditions.
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This question is part of the following fields:
- Urology
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Question 8
Correct
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You are asked to review a middle-aged man, following an admission for lower abdominal pain. The patient has a distended abdomen and has not passed urine for eight hours. He is very uncomfortable and has a large palpable bladder extending above the pubic symphysis. A digital rectal examination is performed, which reveals an enlarged, smooth prostate. Urinalysis is unremarkable, and he remains systemically well. He describes increasing difficulty with voiding and poor stream over the past six months, but no other symptoms.
What is the most likely underlying cause for his urinary retention?Your Answer: Benign prostatic hypertrophy (BPH)
Explanation:Causes of Urinary Retention in Men
Urinary retention, the inability to empty the bladder completely, can have various underlying causes. In men, some common conditions that can lead to urinary retention are benign prostatic hypertrophy (BPH), renal calculi, prostate carcinoma, urinary tract infection, and bladder cancer.
BPH is a non-cancerous enlargement of the prostate gland that often occurs with aging. It can compress the urethra and obstruct the flow of urine, causing symptoms such as difficulty starting urination, weak stream, dribbling, and frequent urination. Immediate treatment for acute urinary retention due to BPH may involve inserting a urinary catheter to relieve the pressure and drain the bladder.
Renal calculi, or kidney stones, can cause urinary retention if they get stuck in the ureter or bladder neck. The pain from passing a stone can be severe and radiate from the back to the groin. Blood in the urine may also be present.
Prostate carcinoma, or prostate cancer, can also cause urinary retention if the tumour grows large enough to block the urethra. However, this is not a common presentation of prostate cancer, which usually manifests with other symptoms such as urinary frequency, urgency, nocturia, pain, or blood in the semen.
Urinary tract infection (UTI) can result from incomplete voiding due to BPH or other causes. UTI can cause symptoms such as burning, urgency, frequency, cloudy or foul-smelling urine, and fever. However, not all cases of urinary retention are associated with UTI.
Bladder cancer is a rare cause of urinary retention, but it can occur if the tumour obstructs the bladder outlet. Bladder cancer may also cause painless hematuria, urinary urgency, or pelvic discomfort.
In summary, urinary retention in men can have multiple etiologies, and the diagnosis depends on the patient’s history, physical examination, and additional tests such as imaging, urinalysis, or prostate-specific antigen (PSA) testing. Prompt evaluation and management of urinary retention are essential to prevent complications such as urinary tract infection, bladder damage, or renal impairment.
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This question is part of the following fields:
- Urology
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Question 9
Incorrect
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A 58-year-old woman comes to the GP with a complaint of occasional urine leakage and increased urinary frequency. She has noticed this for the past few days and also reports slight suprapubic tenderness. The patient is concerned about the embarrassment caused by this condition and its impact on her daily activities. What is the most appropriate initial test to perform for this patient?
Your Answer: Urine cultures
Correct Answer: Urinalysis
Explanation:When dealing with patients who have urinary incontinence, it is important to rule out the possibility of a urinary tract infection (UTI) or diabetes mellitus. Therefore, the first investigation should always be a urinalysis. However, for patients over 65 years old, urinalysis is not a reliable indicator of UTIs as asymptomatic bacteriuria is common in this age group. As this patient is under 65 years old, a urinalysis should be performed.
Blood cultures are only necessary if there is a suspicion of a systemic infection. In this case, the patient is not showing any signs of a systemic infection and is otherwise healthy, making an uncomplicated UTI or diabetes more likely. Therefore, blood cultures are not required for diagnosis.
Renal ultrasound is not typically used to diagnose a lower UTI. However, imaging may be necessary if there are any complicating factors such as urinary tract obstruction.
If the urinalysis suggests a UTI, urine cultures may be performed to identify the organism and determine the appropriate antibiotic sensitivities.
Understanding Urinary Incontinence: Causes, Classification, and Management
Urinary incontinence (UI) is a common condition that affects around 4-5% of the population, with elderly females being more susceptible. Several risk factors contribute to UI, including advancing age, previous pregnancy and childbirth, high body mass index, hysterectomy, and family history. UI can be classified into different types, such as overactive bladder (OAB)/urge incontinence, stress incontinence, mixed incontinence, overflow incontinence, and functional incontinence.
Initial investigation of UI involves completing bladder diaries for at least three days, vaginal examination, urine dipstick and culture, and urodynamic studies. Management of UI depends on the predominant type of incontinence. For urge incontinence, bladder retraining and bladder stabilizing drugs such as antimuscarinics are recommended. For stress incontinence, pelvic floor muscle training and surgical procedures such as retropubic mid-urethral tape procedures may be offered. Duloxetine, a combined noradrenaline and serotonin reuptake inhibitor, may also be used as an alternative to surgery.
In summary, understanding the causes, classification, and management of UI is crucial in providing appropriate care for patients. Early diagnosis and intervention can significantly improve the quality of life for those affected by this condition.
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This question is part of the following fields:
- Urology
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Question 10
Incorrect
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A 56-year-old man visits his doctor with complaints of difficulty maintaining an erection, which has been ongoing for some time and is causing problems in his relationship. He is generally healthy, except for high blood pressure that is managed with amlodipine. He reports still experiencing morning erections and has not noticed any changes in his sex drive. During the examination, his blood pressure is measured at 145/78 mmHg, and his BMI is 30 kg/m2. His abdominal, genital, and prostate exams are all normal. What is the most crucial test to rule out any organic causes for his difficulty maintaining an erection?
Your Answer: Prostate-specific antigen (PSA)
Correct Answer: HbA1c
Explanation:Investigations for Erectile Dysfunction: Assessing Cardiovascular Risk Factors
Erectile dysfunction can have both psychological and organic causes. In this case, the patient still experiences morning erections, suggesting a functional overlay. However, it is important to screen for cardiovascular risk factors, as they are the most common cause of erectile dysfunction. This includes assessing HbA1c or fasting blood glucose and lipid profile, especially since the patient has a high BMI and is at increased risk of diabetes and high cholesterol. Ambulatory blood pressure monitoring may also be necessary, given the patient’s history of hypertension. While repeat blood pressure checks are important, they would not rule out other organic causes for the patient’s symptoms. It is crucial to investigate for both organic and psychological causes of erectile dysfunction, even if the cause is believed to be functional. Prostate-specific antigen testing is not necessary in this case, as the genital and prostate examination were normal. Testosterone levels may also be assessed, but since the patient reports good libido and morning erections, low testosterone is unlikely to be the cause.
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This question is part of the following fields:
- Urology
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