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Question 1
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A 25-year-old man presents to his General Practitioner with a 1-week history of an itchy rash on the inner aspect of his elbows on either side. He states that this came on suddenly and that he has had similar episodes in the past, the first of which occurred when he was around seven years old. He claims to only suffer from generally dry skin and asthma, which he controls with emollient creams and inhalers, respectively.
Given the likely diagnosis, which of the following is the best next step?Your Answer: No further testing required; start treatment
Explanation:Diagnosis and Testing for Atopic Eczema
Atopic eczema is a common skin condition that can cause significant physical and psychological distress to patients. Diagnosis is usually made based on clinical presentation and history, with no further testing required. The UK Working Party Diagnostic Criteria can be used to aid in diagnosis. Treatment options include emollients, topical steroids, and other medications in severe cases.
Radioallergosorbent testing (RAST) and skin patch testing are not useful in diagnosing atopic eczema, as they are mainly used for other types of hypersensitivity reactions. Skin prick testing may be used to diagnose allergies that could be exacerbating the eczema. However, it is important to note that atopic eczema is a clinical diagnosis and testing is not always necessary.
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This question is part of the following fields:
- Dermatology
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Question 2
Correct
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A 58-year-old with a history of acne rosacea seeks guidance on treatment options. Which of the following interventions is least helpful in managing the condition?
Your Answer: Low-dose topical corticosteroids
Explanation:Understanding Rosacea: Symptoms and Management
Rosacea, also known as acne rosacea, is a chronic skin condition that has no known cause. It typically affects the nose, cheeks, and forehead, and the first symptom is often flushing. Over time, telangiectasia (visible blood vessels) may appear, followed by persistent redness with papules and pustules. In some cases, rhinophyma (enlarged nose) may develop, and there may be ocular involvement, such as blepharitis. Sunlight can exacerbate symptoms.
Mild cases of rosacea may be treated with topical metronidazole, while topical brimonidine gel may be used for patients with predominant flushing but limited telangiectasia. More severe cases may require systemic antibiotics like oxytetracycline. Patients are advised to apply high-factor sunscreen daily and use camouflage creams to conceal redness. Laser therapy may be appropriate for those with prominent telangiectasia, and patients with rhinophyma should be referred to a dermatologist.
Overall, understanding the symptoms and management of rosacea can help individuals manage their condition and improve their quality of life.
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This question is part of the following fields:
- Dermatology
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Question 3
Incorrect
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A 30-year-old male patient comes to you with a rash that has spread all over his body. He has multiple erythematous lesions less than 1 cm in diameter on his torso and limbs, some of which are covered by a fine scale. Two weeks ago, he had exudative tonsillitis when he was seen with a sore throat. Apart from asthma, he has no other medical history. What is the probable diagnosis?
Your Answer: Pityriasis rosea
Correct Answer: Guttate psoriasis
Explanation:Tear-drop scaly papules suddenly appearing on the trunk and limbs may indicate guttate psoriasis.
Guttate psoriasis is a type of psoriasis that is more commonly seen in children and adolescents. It is often triggered by a streptococcal infection that occurred 2-4 weeks prior to the appearance of the lesions. The name guttate comes from the Latin word for drop, as the lesions appear as small, tear-shaped papules on the trunk and limbs. These papules are pink and scaly, and the onset of the condition is usually acute, occurring over a few days.
In most cases, guttate psoriasis will resolve on its own within 2-3 months. There is no clear evidence to support the use of antibiotics to treat the underlying streptococcal infection. Treatment options for guttate psoriasis include topical agents commonly used for psoriasis and UVB phototherapy. In cases where the condition recurs, a tonsillectomy may be necessary.
It is important to differentiate guttate psoriasis from pityriasis rosea, another skin condition that can present with similar symptoms. Guttate psoriasis is often preceded by a streptococcal sore throat, while pityriasis rosea may be preceded by a respiratory tract infection. The appearance of guttate psoriasis is characterized by tear-shaped papules on the trunk and limbs, while pityriasis rosea presents with a herald patch followed by multiple oval lesions with a fine scale. While guttate psoriasis resolves within a few months, pityriasis rosea typically resolves after around 6 weeks.
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This question is part of the following fields:
- Dermatology
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Question 4
Incorrect
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A 24-year-old pregnant woman visits her General Practitioner with a rapidly growing lesion on the tip of her index finger. It began as a small spot but has rapidly increased in size over the past five days. It is dark red in colour and causes discomfort and easy bleeding when working in her café.
What is the most probable diagnosis?
Choose the ONE most likely diagnosis from the options below.Your Answer: Haemangioma
Correct Answer: Pyogenic granuloma
Explanation:Differentiating Skin Lesions: Pyogenic Granuloma, BCC, Haemangioma, Melanoma, and Viral Wart
Skin lesions can be caused by various factors, and it is important to differentiate them to determine the appropriate treatment. Here are some common skin lesions and their characteristics:
Pyogenic Granuloma
Pyogenic granulomas are benign vascular lesions that grow rapidly and bleed easily. They appear as a fleshy nodule and can be polyploid. They commonly occur in children, young adults, and pregnancy and are often found on the fingers and hands.Basal Cell Carcinoma (BCC)
BCC is a slow-growing, locally invasive lesion that appears on sun-exposed skin. It has a characteristic rolled edge and is more prevalent in elderly patients with fair skin and a history of sun exposure. BCC can be skin-colored, pink, or pigmented.Haemangioma
Haemangiomas are benign lesions caused by a collection of blood vessels under the skin. They commonly occur in infants and are known as strawberry marks. A new lesion that grows rapidly is unlikely to be a haemangioma.Melanoma
Melanoma is a malignant tumour that arises from the over-proliferation of cutaneous melanocytes. It can occur anywhere on the body and has characteristic asymmetry, border irregularity, color variation, and large diameter. The ABCDE criteria of melanoma can help in identifying it.Viral Wart
Viral warts are benign skin lesions caused by human papillomavirus infection. They commonly occur in school-aged children and have a rough, hyperkeratotic surface.In conclusion, identifying the characteristics of different skin lesions can help in determining the appropriate treatment and management. It is important to seek medical advice if there is any doubt about the nature of a skin lesion.
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This question is part of the following fields:
- Dermatology
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Question 5
Correct
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A 28-year-old woman presents to the general practice clinic with a history of itchy palms and soles for a few weeks. Examination reveals pitting to the nails and dry, scaly, fissured skin with areas of pustules on the palms and soles. She is a social drinker but has no other medical conditions.
Which of the following is the most likely diagnosis?
Your Answer: Palmoplantar pustulosis
Explanation:Skin Conditions: Palmoplantar Pustulosis, Bullous Pemphigoid, Contact Dermatitis, Eczema, and Secondary Syphilis
Palmoplantar Pustulosis: A chronic inflammatory skin condition that affects the palms and soles, often associated with chronic plaque psoriasis and smoking. It presents with painful cracking, fissuring, and crops of sterile pustules that are severely itchy. Topical treatments and phototherapy can be used.
Bullous Pemphigoid: An autoimmune skin disease that forms large fluid-filled blisters, typically affecting people over 80 years old with underlying neurological or malignant conditions. The age and presenting features in this man are not typical for bullous pemphigoid.
Contact Dermatitis: A type of eczema triggered by contact with a particular substance, causing a red, dry, and scaly rash only in the areas that have been in contact with the irritant. Pustules are not a feature of this condition, and it would be unusual for an irritant to have been in contact with the palms and soles.
Eczema: A chronic, itchy, inflammatory skin condition that commonly begins in childhood and affects flexural areas such as behind the knees or in the antecubital fossae. The palms of hands and soles of feet are usually spared.
Secondary Syphilis: A rash that may appear as rough, red or reddish-brown papules or patches, typically occurring on the trunk but frequently affecting the palms and soles. The rash doesn’t itch and can appear more obvious with physical activity or heat. It resolves spontaneously within several weeks but can recur over the next two years.
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This question is part of the following fields:
- Dermatology
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Question 6
Incorrect
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A 60-year-old smoker presents with non-healing sores on his lower lip that have been gradually enlarging for several months. Upon examination, a lesion is found at the vermilion border of the lower lip. What is the most probable type of lesion?
Your Answer: Leukoplakia
Correct Answer: Squamous cell carcinoma (SCC)
Explanation:Common Skin Lesions and Cancers: Characteristics and Clinical Presentations
Squamous cell carcinoma (SCC), actinic keratosis, Bowen’s disease, cold sores, and leukoplakia are common skin lesions and cancers that have distinct characteristics and clinical presentations.
SCC is a malignant tumour that commonly affects the backs of the hands and forearms, the upper part of the face, and the lower lip and pinna in men. The first clinical sign is induration, which may take on nodular, plaque-like, verrucous, or ulcerated characteristics. The limits of induration are not sharp and usually extend beyond the visible margins of the lesion. The surrounding tissue is often inflamed. SCCs rarely metastasize.
Actinic keratosis is a sun-induced scaly or hyperkeratotic lesion that has the potential to become malignant. It is characterized by multifocal, scaly, hyperpigmented or scaly lesions, usually brown with a scaly base, occurring on the head, neck, forearms, and hands.
Bowen’s disease is an intraepidermal (in situ) squamous cell carcinoma that arises in sun-exposed sites, especially the lower legs in women. It is characterized by well-defined pink and scaly patches or plaques that may become crusty, fissured, or ulcerated as lesions grow.
Cold sores are recurrent infections of orofacial herpes simplex that present as grouped vesicles, especially of the lips and perioral skin. The eruption is often preceded by a tingling, itching, or burning sensation. Over a few days, the vesicles form a crust, and the eruption resolves within 7–10 days.
Leukoplakia is a white patch or plaque of the oral mucosa that cannot be characterized clinically or pathologically as any other condition.
A non-healing lesion is also of concern, especially in patients with a history of smoking and advanced age, as it may indicate a malignant cause. Early detection and treatment are crucial in preventing the progression of these skin lesions and cancers.
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This question is part of the following fields:
- Dermatology
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Question 7
Correct
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A 56-year-old man with a history of type 2 diabetes mellitus and benign prostatic hyperplasia presents to dermatology with multiple lesions on his shin. Upon examination, symmetrical, tender, erythematous nodules are observed. The lesions are healing without scarring. What is the probable diagnosis?
Your Answer: Erythema nodosum
Explanation:The relevant diagnosis for this question relies solely on the description of the lesions, as the patient’s medical history is not a factor. Specifically, the tender shin lesions are indicative of erythema nodosum.
Understanding Shin Lesions: Differential Diagnosis and Characteristic Features
Shin lesions can be caused by a variety of conditions, and it is important to differentiate between them in order to provide appropriate treatment. The four most common conditions that can cause shin lesions are erythema nodosum, pretibial myxoedema, pyoderma gangrenosum, and necrobiosis lipoidica diabeticorum.
Erythema nodosum is characterized by symmetrical, tender, erythematous nodules that heal without scarring. It is often caused by streptococcal infections, sarcoidosis, inflammatory bowel disease, or certain medications such as penicillins, sulphonamides, or oral contraceptive pills.
Pretibial myxoedema, on the other hand, is seen in Graves’ disease and is characterized by symmetrical, erythematous lesions that give the skin a shiny, orange peel appearance.
Pyoderma gangrenosum initially presents as a small red papule, which later develops into deep, red, necrotic ulcers with a violaceous border. It is idiopathic in 50% of cases, but may also be seen in inflammatory bowel disease, connective tissue disorders, and myeloproliferative disorders.
Finally, necrobiosis lipoidica diabeticorum is characterized by shiny, painless areas of yellow/red skin typically found on the shin of diabetics. It is often associated with telangiectasia.
In summary, understanding the differential diagnosis and characteristic features of shin lesions can help healthcare professionals provide appropriate treatment and improve patient outcomes.
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This question is part of the following fields:
- Dermatology
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Question 8
Incorrect
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Which one of the following is not a management option for individuals with hyperhidrosis?
Your Answer: Topical aluminium chloride
Correct Answer: Topical atropine
Explanation:Hyperhidrosis is a condition characterized by the excessive production of sweat. To manage this condition, there are several options available. The first-line treatment is the use of topical aluminium chloride preparations, although it may cause skin irritation as a side effect. Iontophoresis is another option that is particularly useful for patients with palmar, plantar, and axillary hyperhidrosis. Botulinum toxin is also licensed for axillary symptoms. Surgery, such as Endoscopic transthoracic sympathectomy, is another option, but patients should be informed of the risk of compensatory sweating. Overall, there are various management options available for hyperhidrosis, and patients should discuss with their healthcare provider to determine the best course of action.
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This question is part of the following fields:
- Dermatology
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Question 9
Incorrect
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A 55-year-old diabetic female patient comes in with bilateral erythematous lesions on her shins that have been present for four months. The lesions are surrounded by telangiectasia. What is the probable diagnosis?
Your Answer: Erythema nodosum
Correct Answer: Necrobiosis lipoidica
Explanation:There is no association between erythema nodosum and telangiectasia in the surrounding area.
Skin Disorders Linked to Diabetes
Diabetes mellitus is a chronic metabolic disorder that affects various organs in the body, including the skin. Several skin disorders are associated with diabetes, including necrobiosis lipoidica, infections such as candidiasis and staphylococcal, neuropathic ulcers, vitiligo, lipoatrophy, and granuloma annulare. Necrobiosis lipoidica is characterized by shiny, painless areas of yellow, red, or brown skin, typically on the shin, and is often associated with surrounding telangiectasia. Infections such as candidiasis and staphylococcal can also occur in individuals with diabetes. Neuropathic ulcers are a common complication of diabetes, and vitiligo and lipoatrophy are also associated with the condition. Granuloma annulare is a papular lesion that is often slightly hyperpigmented and depressed centrally, but recent studies have not confirmed a significant association between diabetes mellitus and this skin disorder. It is important for individuals with diabetes to be aware of these potential skin complications and to seek medical attention if they notice any changes in their skin.
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This question is part of the following fields:
- Dermatology
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Question 10
Correct
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A 16-year-old female from Nigeria comes to the clinic with a swelling near her earlobe. She had her ears pierced three months ago and has noticed a gradual development of an erythematous swelling. Upon examination, a keloid scar is observed. What is the best course of action for management?
Your Answer: Refer for intralesional triamcinolone
Explanation:Understanding Keloid Scars
Keloid scars are abnormal growths that develop from the connective tissue of a scar and extend beyond the boundaries of the original wound. They are more common in people with dark skin and tend to occur in young adults. Keloids are most frequently found on the sternum, shoulder, neck, face, extensor surface of limbs, and trunk.
To prevent keloid scars, incisions should be made along relaxed skin tension lines. However, if keloids do develop, early treatment with intra-lesional steroids such as triamcinolone may be effective. In some cases, excision may be necessary, but this should be approached with caution as it can potentially lead to further keloid scarring.
It is important to note that the historical use of Langer lines to determine optimal incision lines has been shown to produce worse cosmetic results than following skin tension lines. Understanding the predisposing factors and treatment options for keloid scars can help individuals make informed decisions about their care.
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This question is part of the following fields:
- Dermatology
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