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Question 1
Incorrect
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A 25-year-old man with a known harsh ejection systolic murmur on cardiac examination collapses and passes away during a sporting event. His father and uncle also died suddenly in their forties. The reason for death is identified as an obstruction of the ventricular outflow tract caused by an abnormality in the ventricular septum.
What is the accurate diagnosis for this condition?Your Answer: Ventricular septal defect
Correct Answer: Hypertrophic cardiomyopathy
Explanation:Types of Cardiomyopathy and Congenital Heart Defects
Cardiomyopathy is a group of heart diseases that affect the structure and function of the heart muscle. There are different types of cardiomyopathy, each with its own causes and symptoms. Additionally, there are congenital heart defects that can affect the heart’s structure and function from birth. Here are some of the most common types:
1. Hypertrophic cardiomyopathy: This is an inherited condition that causes the heart muscle to thicken, making it harder for the heart to pump blood. It can lead to sudden death in young athletes.
2. Restrictive cardiomyopathy: This is a rare form of cardiomyopathy that is caused by diseases that restrict the heart’s ability to fill with blood during diastole.
3. Dilated cardiomyopathy: This is the most common type of cardiomyopathy, which causes the heart chambers to enlarge and weaken, leading to heart failure.
4. Mitral stenosis: This is a narrowing of the mitral valve, which can impede blood flow between the left atrium and ventricle.
In addition to these types of cardiomyopathy, there are also congenital heart defects, such as ventricular septal defect, which is the most common congenital heart defect. This condition creates a direct connection between the right and left ventricles, affecting the heart’s ability to pump blood effectively.
Understanding the different types of cardiomyopathy and congenital heart defects is important for proper diagnosis and treatment. If you experience symptoms such as chest pain, shortness of breath, or fatigue, it is important to seek medical attention promptly.
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This question is part of the following fields:
- Cardiology
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Question 2
Correct
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A 54-year-old man comes to his doctor for a regular check-up after experiencing a heart attack 6 weeks ago. During the examination, he appears unwell, sweaty, and clammy, and mentions feeling constantly feverish. His recent blood work reveals an elevated erythrocyte sedimentation rate (ESR) and anemia. What is the most probable post-heart attack complication that this man is experiencing?
Your Answer: Dressler’s syndrome
Explanation:Complications Following Myocardial Infarction
One of the complications that can occur 2-6 weeks after a myocardial infarction (MI) is Dressler’s syndrome. This autoimmune reaction happens as the myocardium heals and can present with pyrexia, pleuritic chest pain, and an elevated ESR. Pulmonary embolism is not suggested by this presentation. Another complication is myomalacia cordis, which occurs 3-14 days post-MI and involves the softening of dead muscles leading to rupture and death. Ventricular aneurysm may also form due to weakened myocardium, resulting in persistent ST elevation and left ventricular failure. Anticoagulation is necessary to prevent thrombus formation within the aneurysm and reduce the risk of stroke. Heart failure is unlikely to cause the above presentation and blood test results.
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This question is part of the following fields:
- Cardiology
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Question 3
Correct
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A 55-year-old man presents to the clinic with complaints of chest pain and difficulty breathing. He had been hospitalized four weeks ago for acute coronary syndrome and was discharged on bisoprolol, simvastatin, aspirin, and ramipril. During the examination, a narrow complex tachycardia is observed. What is the absolute contraindication in this scenario?
Your Answer: Verapamil
Explanation:Verapamil and Beta Blockers: A Dangerous Combination
Verapamil is a type of medication that blocks calcium channels in the heart, leading to a decrease in cardiac output and a slower heart rate. However, it also has negative effects on the heart’s ability to contract, making it a highly negatively inotropic drug. Additionally, it may impair the conduction of electrical signals between the atria and ventricles of the heart.
According to the British National Formulary (BNF), verapamil should not be given to patients who are already taking beta blockers. This is because the combination of these two drugs can lead to dangerously low blood pressure and even asystole, a condition where the heart stops beating altogether.
Therefore, it is important for healthcare professionals to carefully consider a patient’s medication history before prescribing verapamil. If a patient is already taking beta blockers, alternative treatments should be considered to avoid the potentially life-threatening consequences of combining these two drugs.
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This question is part of the following fields:
- Cardiology
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Question 4
Correct
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A 72-year-old woman visits her GP for a routine check-up. During the examination, she seems generally healthy but slightly fatigued and experiences some breathlessness at rest. Her pulse is irregularly irregular and measures 72 bpm, while her blood pressure is 126/78 mmHg. Upon further examination, no concerning issues are found. The patient has no significant medical history and is not taking any regular medications.
What is the probable reason for this woman's development of atrial fibrillation (AF)?Your Answer: Lone AF
Explanation:Management of Atrial Fibrillation: The ABCD Approach
Atrial fibrillation (AF) is a common arrhythmia that can be classified as paroxysmal, persistent, or permanent. Treatment options for AF depend on the classification and can be categorized into rate control, rhythm control, and anticoagulation. The ABCD approach is a useful tool for managing AF.
A – Anticoagulation: Patients with AF are at an increased risk for thromboembolic disease, and anticoagulation should be considered in high-risk patients where the benefit outweighs the risk of hemorrhage.
B – Better symptom control: Rate control is aimed at controlling the ventricular response rate to improve symptoms. Rhythm control is aimed at restoring and maintaining sinus rhythm to improve symptoms.
C – Cardiovascular risk factor management: Management of underlying cardiovascular risk factors such as hypertension, diabetes, and hyperlipidemia can help reduce the risk of AF recurrence and complications.
D – Disease management: Management of underlying conditions associated with AF, such as valvular heart disease and heart failure, can help improve AF outcomes.
In summary, the ABCD approach to managing AF involves anticoagulation, better symptom control, cardiovascular risk factor management, and disease management. This approach can help improve outcomes and reduce the risk of complications in patients with AF.
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This question is part of the following fields:
- Cardiology
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Question 5
Incorrect
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A patient presents to the Emergency Department following a fracture dislocation of his ankle after a night out drinking vodka red-bulls. His blood pressure is low at 90/50 mmHg. He insists that it is never normally that low.
Which one of these is a possible cause for this reading?Your Answer: Alcohol and caffeine
Correct Answer: Incorrect cuff size (cuff too large)
Explanation:Common Factors Affecting Blood Pressure Readings
Blood pressure readings can be affected by various factors, including cuff size, alcohol and caffeine consumption, white coat hypertension, pain, and more. It is important to be aware of these factors to ensure accurate readings.
Incorrect Cuff Size:
Using a cuff that is too large can result in an underestimation of blood pressure, while a cuff that is too small can cause a falsely elevated reading.Alcohol and Caffeine:
Both alcohol and caffeine can cause a temporary increase in blood pressure.White Coat Hypertension:
Many patients experience elevated blood pressure in medical settings due to anxiety. To obtain an accurate reading, blood pressure should be measured repeatedly on separate occasions.Pain:
Pain is a common cause of blood pressure increase and should be taken into consideration during medical procedures. A significant rise in blood pressure during a procedure may indicate inadequate anesthesia.Factors Affecting Blood Pressure Readings
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This question is part of the following fields:
- Cardiology
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Question 6
Correct
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A 48-year-old man presents to the Emergency Department with chest tightness. His blood pressure is 200/105 mmHg and heart rate is 70 bpm. His femoral pulses cannot be felt. Echocardiography reveals cardiomegaly and a left-ventricular ejection fraction of 34%. The patient also has a N-terminal pro-brain natriuretic peptide (NT-proBNP) of 25,000 pg/mL. As a result of the patient’s hypertension and high levels of NT-proBNP, he undergoes coronary angiography to exclude cardiac ischaemia. There is no evidence of myocardial ischaemia, but there are significant arterial findings.
Which of the following is most likely to be seen on coronary angiography of this patient?Your Answer: Stenotic arteries
Explanation:Differentiating Arterial Conditions: Understanding the Symptoms and Causes
When it comes to arterial conditions, it is important to understand the symptoms and causes in order to make an accurate diagnosis. Here, we will explore several potential conditions and how they may present in a patient.
Stenotic Arteries:
Coarctation of the aorta is a potential condition to consider in younger adults with poorly controlled hypertension. Symptoms may include weak or absent femoral pulses, heart failure, and left-ventricular hypertrophy. Angiography may reveal stenosis in the middle and proximal segments of the left anterior descending artery, as well as in the left circumflex artery.Thickened Arteries:
Atherosclerosis, or the build-up of plaque in the arteries, is a risk factor for heart attacks and stroke. However, it is unlikely to explain persistently high blood pressure or an absent femoral pulse.Aortic Aneurysm:
While chronic high blood pressure can increase the risk of an aortic aneurysm, sudden, intense chest or back pain is a more common symptom. Additionally, a patient with an aneurysm would likely have low blood pressure and an elevated heart rate, which is inconsistent with the vitals seen in this presentation.Calcified Arteries:
Calcification of arteries is caused by elevated lipid content and increases with age. While it can increase the risk of heart attack and stroke, it would not explain the absence of a femoral pulse or extremely high blood pressure.Patent Foramen Ovale:
This condition, which predisposes patients to paradoxical emboli, is typically diagnosed on an echocardiogram and is unlikely to cause hypertension. It should be considered in patients who have had a stroke before the age of 50.In summary, understanding the symptoms and causes of arterial conditions is crucial for accurate diagnosis and treatment.
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This question is part of the following fields:
- Cardiology
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Question 7
Correct
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A 56-year-old, 80 kg woman arrives at the Emergency Department complaining of chest pain that began 5 hours ago. She has no known allergies and is not taking any regular medications. Her electrocardiogram shows T-wave inversion in lateral leads but no ST changes, and her serum troponin level is significantly elevated. What is the appropriate combination of drugs to administer immediately?
Your Answer: Aspirin 300 mg, prasugrel 60 mg, fondaparinux 2.5 mg
Explanation:For patients with different combinations of medications, the appropriate treatment plan may vary. In general, aspirin should be given as soon as possible and other medications may be added depending on the patient’s condition and the likelihood of undergoing certain procedures. For example, if angiography is not planned within 24 hours of admission, a loading dose of aspirin and prasugrel with fondaparinux may be given. If PCI is planned, unfractionated heparin may be considered. The specific dosages and medications may differ based on the patient’s individual needs and risk factors.
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This question is part of the following fields:
- Cardiology
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Question 8
Incorrect
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A 55-year-old woman has been suffering from significant pain in her lower limbs when walking more than 200 meters for the past six months. During physical examination, her legs appear pale and cool without signs of swelling or redness. The palpation of dorsalis pedis or posterior tibial pulses is not possible. The patient has a body mass index of 33 kg/m2 and has been smoking for 25 pack years. What is the most probable vascular abnormality responsible for these symptoms?
Your Answer: Medial calcific sclerosis
Correct Answer: Atherosclerosis
Explanation:Arteriosclerosis and Related Conditions
Arteriosclerosis is a medical condition that refers to the hardening and loss of elasticity of medium or large arteries. Atherosclerosis, on the other hand, is a specific type of arteriosclerosis that occurs when fatty materials such as cholesterol accumulate in the artery walls, causing them to thicken. This chronic inflammatory response is caused by the accumulation of macrophages and white blood cells, and is often promoted by low-density lipoproteins. The formation of multiple plaques within the arteries characterizes atherosclerosis.
Medial calcific sclerosis is another form of arteriosclerosis that occurs when calcium deposits form in the middle layer of walls of medium-sized vessels. This condition is often not clinically apparent unless it is severe, and it is more common in people over 50 years old and in diabetics. It can be seen as opaque vessels on radiographs.
Lymphatic obstruction, on the other hand, is a blockage of the lymph vessels that drain fluid from tissues throughout the body. This condition may cause lymphoedema, and the most common reason for this is the removal or enlargement of the lymph nodes.
It is important to understand these conditions and their differences to properly diagnose and treat patients.
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This question is part of the following fields:
- Cardiology
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Question 9
Incorrect
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An 82-year-old man has been experiencing increasing shortness of breath, tiredness, intermittent chest pain and leg swelling for the past 6 months. He recently underwent an echocardiogram as an outpatient which revealed evidence of heart failure. As the FY1 on the Medical Assessment Unit, you have been tasked with taking the patient's medical history. He has a history of hypertension and gout and is currently taking diltiazem (calcium-channel blocker) 60 mg po bd, furosemide (diuretic) 20 mg po od, Spironolactone 25mg od, allopurinol 100 mg po od, paracetamol 1 g po qds prn, and lisinopril 20 mg po od. Considering his likely diagnosis of heart failure, which medication should be discontinued?
Your Answer: Lisinopril
Correct Answer: Diltiazem
Explanation:Medications for Heart Failure: Understanding their Effects
Heart failure is a complex condition that requires careful management, including the use of various medications. In this context, it is important to understand the effects of each drug and how they can impact the patient’s health. Here is a brief overview of some commonly used medications for heart failure and their effects:
Diltiazem: This calcium-channel blocker can be used to treat angina and hypertension. However, it is advisable to stop calcium-channel blockers in patients with heart disease, as they can reduce the contractility of the heart, exacerbating the condition.
Spironolactone: This drug can help alleviate leg swelling by reducing water retention. It is also one of the three drugs in heart failure that have been shown to reduce mortality, along with ACE inhibitors and b-blockers.
Allopurinol: This medication is used in the prevention of gout long term and has no detrimental effect on the heart.
Paracetamol: This drug does not have an effect on the heart.
Lisinopril: This ACE inhibitor is used in the treatment of hypertension and the prophylactic treatment of angina. Stopping this medication is likely to worsen heart failure. Like spironolactone and b-blockers, ACE inhibitors have been shown to reduce mortality in heart failure, although the mechanisms behind this effect are not fully understood.
In summary, understanding the effects of medications for heart failure is crucial for optimizing patient care and improving outcomes. Healthcare providers should carefully consider each drug’s benefits and risks and tailor treatment to the individual patient’s needs.
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This question is part of the following fields:
- Cardiology
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Question 10
Correct
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A 70-year-old obese woman is admitted with episodic retrosternal chest pain not relieved by rest, for the past 3 weeks. The pain is described as squeezing in nature, and is not affected by meals or breathing. The episodic pain is of fixed pattern and is of same intensity. She has a background of diabetes mellitus, hyperlipidaemia and hypertension. Her family history is remarkable for a paternal myocardial infarction at the age of 63. She is currently haemodynamically stable.
What is the most likely diagnosis in this patient?Your Answer: Acute coronary syndrome
Explanation:Differentiating Acute Coronary Syndrome from Other Cardiac Conditions
The patient in question presents with retrosternal chest pain that is squeezing in nature and unrelated to meals or breathing. This highly suggests a cardiac origin for the pain. However, the episodic nature of the pain and its duration of onset over three weeks point towards unstable angina, a type of acute coronary syndrome.
It is important to differentiate this condition from other cardiac conditions such as aortic dissection, which presents with sudden-onset tearing chest pain that radiates to the back. Stable angina pectoris, on the other hand, manifests with episodic cardiac chest pain that has a fixed pattern of precipitation, duration, and termination, lasting at least one month.
Myocarditis is associated with a constant stabbing chest pain and recent flu-like symptoms or upper respiratory infection. Aortic stenosis may also cause unstable angina, but the most common cause of this condition is critical coronary artery occlusion.
In summary, careful consideration of the pattern, duration, and characteristics of chest pain can help differentiate acute coronary syndrome from other cardiac conditions.
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This question is part of the following fields:
- Cardiology
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