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Question 1
Incorrect
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A 58-year-old male is referred to dermatology by his physician for evaluation of a lesion on his shin. During the examination, the dermatologist observes shiny, painless areas of yellow skin with numerous telangiectasia. What is the probable diagnosis?
Your Answer: Pyoderma gangrenosum
Correct Answer: Necrobiosis lipoidica diabeticorum
Explanation:Necrobiosis lipoidica diabeticorum is a condition characterized by waxy yellow shin lesions that often occur in individuals with diabetes.
Understanding Shin Lesions: Differential Diagnosis and Characteristic Features
Shin lesions can be caused by a variety of conditions, and it is important to differentiate between them in order to provide appropriate treatment. The four most common conditions that can cause shin lesions are erythema nodosum, pretibial myxoedema, pyoderma gangrenosum, and necrobiosis lipoidica diabeticorum.
Erythema nodosum is characterized by symmetrical, tender, erythematous nodules that heal without scarring. It is often caused by streptococcal infections, sarcoidosis, inflammatory bowel disease, or certain medications such as penicillins, sulphonamides, or oral contraceptive pills.
Pretibial myxoedema, on the other hand, is seen in Graves’ disease and is characterized by symmetrical, erythematous lesions that give the skin a shiny, orange peel appearance.
Pyoderma gangrenosum initially presents as a small red papule, which later develops into deep, red, necrotic ulcers with a violaceous border. It is idiopathic in 50% of cases, but may also be seen in inflammatory bowel disease, connective tissue disorders, and myeloproliferative disorders.
Finally, necrobiosis lipoidica diabeticorum is characterized by shiny, painless areas of yellow/red skin typically found on the shin of diabetics. It is often associated with telangiectasia.
In summary, understanding the differential diagnosis and characteristic features of shin lesions can help healthcare professionals provide appropriate treatment and improve patient outcomes.
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This question is part of the following fields:
- Dermatology
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Question 2
Correct
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A father brings his 4-year-old daughter to your clinic with worsening eczema. He reports that she has developed itchy blisters all over her body, including her face, torso, arms, and legs. Additionally, she is not behaving normally, eating and drinking less than usual, and not engaging with her favorite toys. She also has a fever of 39ºC. What is the most suitable course of action?
Your Answer: Refer urgently to hospital
Explanation:Immediate hospitalization and administration of IV antivirals are necessary for the treatment of eczema herpeticum, a severe condition. The child in question is exhibiting symptoms such as painful blisters, fever, and swollen lymph nodes, which require urgent medical attention. Any delay in seeking medical help could worsen the condition. Therefore, all other options are incorrect and should be avoided.
Understanding Eczema Herpeticum
Eczema herpeticum is a serious skin infection caused by herpes simplex virus 1 or 2. It is commonly observed in children with atopic eczema and is characterized by a rapidly progressing painful rash. The infection can be life-threatening, which is why it is important to seek medical attention immediately.
During examination, doctors typically observe monomorphic punched-out erosions, which are circular, depressed, and ulcerated lesions that are usually 1-3 mm in diameter. Due to the severity of the infection, children with eczema herpeticum should be admitted to the hospital for intravenous aciclovir treatment. It is important to understand the symptoms and seek medical attention promptly to prevent any complications.
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This question is part of the following fields:
- Dermatology
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Question 3
Correct
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A 3-year-old child with a history of atopic eczema presents to the clinic. The child's eczema is typically managed well with emollients, but the parents are worried as the facial eczema has worsened significantly overnight. The child now has painful blisters clustered on both cheeks, around the mouth, and on the neck. The child's temperature is 37.9ºC. What is the best course of action for management?
Your Answer: Admit to hospital
Explanation:IV antivirals are necessary for the treatment of eczema herpeticum, which is a severe condition.
Understanding Eczema Herpeticum
Eczema herpeticum is a serious skin infection caused by herpes simplex virus 1 or 2. It is commonly observed in children with atopic eczema and is characterized by a rapidly progressing painful rash. The infection can be life-threatening, which is why it is important to seek medical attention immediately.
During examination, doctors typically observe monomorphic punched-out erosions, which are circular, depressed, and ulcerated lesions that are usually 1-3 mm in diameter. Due to the severity of the infection, children with eczema herpeticum should be admitted to the hospital for intravenous aciclovir treatment. It is important to understand the symptoms and seek medical attention promptly to prevent any complications.
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This question is part of the following fields:
- Dermatology
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Question 4
Correct
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A 65-year-old man with a history of Parkinson's disease comes to the clinic complaining of an itchy, red rash on his neck, behind his ears, and around the nasolabial folds. He experienced a similar outbreak last year but did not seek medical attention. What is the probable diagnosis?
Your Answer: Seborrhoeic dermatitis
Explanation:Patients with Parkinson’s disease are more likely to experience seborrhoeic dermatitis.
Understanding Seborrhoeic Dermatitis in Adults
Seborrhoeic dermatitis is a chronic skin condition that affects around 2% of the general population. It is caused by an inflammatory reaction related to the overgrowth of a fungus called Malassezia furfur, which is a normal inhabitant of the skin. The condition is characterized by eczematous lesions that appear on the sebum-rich areas of the body, such as the scalp, periorbital, auricular, and nasolabial folds. It can also lead to the development of otitis externa and blepharitis.
Seborrhoeic dermatitis is often associated with other medical conditions, such as HIV and Parkinson’s disease. The management of the condition depends on the affected area. For scalp disease, over-the-counter preparations containing zinc pyrithione and tar are usually the first-line treatment. If these are not effective, ketoconazole is the preferred second-line agent. Selenium sulphide and topical corticosteroids may also be useful.
For the face and body, topical antifungals such as ketoconazole and topical steroids are often used. However, it is important to use steroids for short periods only to avoid side effects. Seborrhoeic dermatitis can be difficult to treat, and recurrences are common. Therefore, it is important to work closely with a healthcare provider to manage the condition effectively.
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This question is part of the following fields:
- Dermatology
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Question 5
Incorrect
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A 50-year-old woman comes in for a check-up. She has recently noticed several areas of pale skin on her hands. Despite using an emollient and topical hydrocortisone, there has been no improvement. During the examination, you observe multiple depigmented patches on the back of both hands. The patient's medical history includes a previous diagnosis of thyrotoxicosis, for which she is currently taking carbimazole and thyroxine. What is the probable reason for her symptoms?
Your Answer: Carbimazole-induced hypopigmentation
Correct Answer: Vitiligo
Explanation:Patients with autoimmune conditions like thyrotoxicosis are more likely to have vitiligo, but there are no other indications in the medical history that point towards Addison’s disease.
Understanding Vitiligo
Vitiligo is a condition that affects the skin, resulting in the loss of melanocytes and causing depigmentation. It is an autoimmune disorder that affects approximately 1% of the population, with symptoms typically appearing between the ages of 20-30 years. The condition is characterized by well-defined patches of depigmented skin, with the peripheries being the most affected. Trauma can also trigger new lesions, known as the Koebner phenomenon.
Vitiligo is often associated with other autoimmune disorders such as type 1 diabetes mellitus, Addison’s disease, autoimmune thyroid disorders, pernicious anemia, and alopecia areata. Management of the condition includes the use of sunblock for affected areas of skin, camouflage make-up, and topical corticosteroids, which may reverse the changes if applied early. There may also be a role for topical tacrolimus and phototherapy, although caution needs to be exercised with light-skinned patients.
In summary, vitiligo is a condition that affects the skin, resulting in depigmentation. It is an autoimmune disorder that can be managed with various treatments, including sunblock, make-up, and topical corticosteroids. It is often associated with other autoimmune disorders, and caution should be exercised when using certain treatments.
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This question is part of the following fields:
- Dermatology
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Question 6
Incorrect
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A 25-year-old female with a past medical history of anorexia nervosa complains of red crusted lesions located at the corners of her mouth and below her lower lip. What nutrient deficiency is she most likely experiencing?
Your Answer: Magnesium
Correct Answer: Zinc
Explanation:Angular cheilitis can also be caused by a lack of vitamin B2 (riboflavin).
Understanding Zinc Deficiency and Acrodermatitis Enteropathica
Zinc deficiency is a condition that can lead to a range of symptoms, including acrodermatitis, which is characterized by red, crusted lesions that appear in an acral distribution, peri-orificial, perianal, and alopecia. Other symptoms of zinc deficiency include short stature, hypogonadism, hepatosplenomegaly, geophagia (ingesting clay/soil), cognitive impairment, and more.
One specific type of zinc deficiency is known as acrodermatitis enteropathica, which is a recessively inherited partial defect in intestinal zinc absorption. This condition can lead to a range of symptoms, including the characteristic skin lesions, as well as other physical and cognitive impairments. It is important to recognize the signs of zinc deficiency and seek appropriate treatment to prevent further complications. With proper management, individuals with zinc deficiency can lead healthy and fulfilling lives.
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This question is part of the following fields:
- Dermatology
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Question 7
Correct
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A 45-year-old woman presents to the Dermatology Clinic for regular follow-up of her psoriasis. This had previously been well controlled after phototherapy six months ago; however, she has recently deteriorated.
Her current treatment regime includes topical calcipotriol (Dovonex), topical coal tar ointment and topical hydromol ointment, in addition to amoxicillin for a recent respiratory infection. She is otherwise fit and well.
On examination, she has an erythematous rash covering much of her back, with widespread patches on her arms and legs. The rash is tender and warm, though she appears to be shivering. There are no oral lesions. Her pulse is 98 beats per minute, while her blood pressure (BP) is 95/50 mmHg and her temperature is 38.2 °C.
What is the most important next step in this woman's treatment?Your Answer: Arrange hospital admission
Explanation:Urgent Hospital Admission Required for Erythrodermic Psoriasis
Erythrodermic psoriasis is a severe dermatological emergency that requires urgent hospital admission. This is evident in a patient who presents with a drop in blood pressure, tachycardia, borderline pyrexia, and rigors. While the patient’s psoriasis needs more intensive management, it is not appropriate to manage erythroderma in the community.
The treatment for erythrodermic psoriasis includes supportive care, such as intravenous fluids, cool, wet dressings, and a systemic agent. The choice of a systemic agent depends on the patient and may involve rapid-acting therapies like ciclosporin or slower agents like methotrexate. However, it is important to note that starting any systemic agent requires investigations, including baseline blood tests and a viral screen, to ensure it is not contraindicated.
It is crucial to differentiate erythrodermic psoriasis from other dermatological emergencies like Stevens-Johnson syndrome/toxic epidermal necrolysis (TEN), which is a severe drug reaction associated with amoxicillin and anti-epileptic therapies. However, in this case, the patient’s history features a slow deterioration of pre-existing psoriasis, and the rash is not desquamating, and there are no oral lesions. Therefore, hospital admission is required for erythrodermic psoriasis.
It is essential to avoid repeating phototherapy in a patient with erythrodermic psoriasis as it can worsen the condition. In a well patient, phototherapy would not be reattempted six months after a poor response, and an alternate approach would most likely be sought.
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This question is part of the following fields:
- Dermatology
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Question 8
Correct
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A 32-year-old male presents to his GP with a complaint of rectal bleeding and black stool. He reports experiencing this issue more than six times in the past four months. The patient denies any other symptoms such as weight loss, abdominal pain, or changes in bowel habits. During the examination, no masses or apparent causes of bleeding are found in his abdomen or rectum. However, the GP notices some red spots on the patient's lips and tongue. When questioned about them, the patient dismisses them as insignificant and claims that everyone in his family has them. What is the most probable reason for the bleeding?
Your Answer: Hereditary haemorrhagic telangiectasia
Explanation:Rectal bleeding can have various causes, and it is crucial to differentiate between them as the treatments and prognosis can differ significantly. By utilizing signs and examinations, one can eliminate possibilities. If there are no masses, weight loss, or changes in bowel habits, rectal or colon cancer is less probable. Similarly, if there are no changes in bowel habits, abdominal pain, or weight loss, Crohn’s disease is less likely. This narrows down the possibilities to Louis-Bar syndrome and hereditary haemorrhagic telangiectasia. Louis-Bar syndrome, also known as ataxia telangiectasia, is a rare neurodegenerative disorder that typically manifests in early childhood with severe ataxia and other neurological symptoms.
Understanding Hereditary Haemorrhagic Telangiectasia
Hereditary haemorrhagic telangiectasia, also known as Osler-Weber-Rendu syndrome, is a genetic condition that is inherited in an autosomal dominant manner. It is characterized by the presence of multiple telangiectasia on the skin and mucous membranes. While 80% of cases have a family history, 20% occur spontaneously without prior family history.
There are four main diagnostic criteria for HHT. If a patient has two of these criteria, they are said to have a possible diagnosis of HHT. If they meet three or more of the criteria, they are said to have a definite diagnosis of HHT. These criteria include spontaneous, recurrent nosebleeds (epistaxis), multiple telangiectases at characteristic sites such as the lips, oral cavity, fingers, and nose, visceral lesions such as gastrointestinal telangiectasia (with or without bleeding), pulmonary arteriovenous malformations (AVM), hepatic AVM, cerebral AVM, and spinal AVM, and a first-degree relative with HHT.
In summary, HHT is a genetic condition that is characterized by multiple telangiectasia on the skin and mucous membranes. It can be diagnosed based on the presence of certain criteria, including nosebleeds, telangiectases, visceral lesions, and family history.
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This question is part of the following fields:
- Dermatology
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Question 9
Incorrect
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A 38-year-old man presents with pruritic, violaceous papules in a polygonal pattern on the flexor surface of his forearms. Several of these papules have merged to form plaques. What is the probable diagnosis?
Your Answer: Psoriasis
Correct Answer: Lichen planus
Explanation:Lichen planus is a rash that appears as purple, itchy, polygonal papules on the flexor surfaces of the body. It is often accompanied by Wickham’s striae on the surface and can also affect the mouth. In contrast, lichen sclerosus is characterized by white, itchy spots that commonly appear on the vulva of older women.
Understanding Lichen Planus
Lichen planus is a skin condition that is believed to be caused by an immune response, although the exact cause is unknown. It is characterized by an itchy, papular rash that typically appears on the palms, soles, genitalia, and flexor surfaces of the arms. The rash often has a polygonal shape and a distinctive white-lines pattern on the surface, known as Wickham’s striae. In some cases, new skin lesions may appear at the site of trauma, a phenomenon known as the Koebner phenomenon.
Oral involvement is common in around 50% of patients, with a white-lace pattern often appearing on the buccal mucosa. Nail changes may also occur, including thinning of the nail plate and longitudinal ridging. Lichenoid drug eruptions can be caused by certain medications, such as gold, quinine, and thiazides.
The main treatment for lichen planus is potent topical steroids. For oral lichen planus, benzydamine mouthwash or spray is recommended. In more extensive cases, oral steroids or immunosuppression may be necessary.
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This question is part of the following fields:
- Dermatology
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Question 10
Correct
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A 42-year-old woman comes to the clinic complaining of itchy, violaceous papules on the flexor aspects of her wrists. She has no significant medical history and has never experienced a similar rash before. Based on the probable diagnosis, what other symptom is she most likely to exhibit?
Your Answer: Mucous membrane involvement
Explanation:Lichen planus is a skin condition characterized by a rash of purple, itchy, polygonal papules on the flexor surfaces of the body. The affected area may also have Wickham’s striae. Oral involvement is common. In addition, elderly women may experience itchy white spots on the vulva, known as lichen sclerosus. Mucous membrane involvement is also frequently observed in lichen planus.
Understanding Lichen Planus
Lichen planus is a skin condition that is believed to be caused by an immune response, although the exact cause is unknown. It is characterized by an itchy, papular rash that typically appears on the palms, soles, genitalia, and flexor surfaces of the arms. The rash often has a polygonal shape and a distinctive white-lines pattern on the surface, known as Wickham’s striae. In some cases, new skin lesions may appear at the site of trauma, a phenomenon known as the Koebner phenomenon.
Oral involvement is common in around 50% of patients, with a white-lace pattern often appearing on the buccal mucosa. Nail changes may also occur, including thinning of the nail plate and longitudinal ridging. Lichenoid drug eruptions can be caused by certain medications, such as gold, quinine, and thiazides.
The main treatment for lichen planus is potent topical steroids. For oral lichen planus, benzydamine mouthwash or spray is recommended. In more extensive cases, oral steroids or immunosuppression may be necessary.
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This question is part of the following fields:
- Dermatology
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Question 11
Incorrect
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A 35-year-old man presents to his General Practitioner. He has noticed a few patches of pale skin on his arms over the past few weeks. He is not particularly worried about these but wants to know what it could be and what he needs to do about it.
On examination, a few depigmented patches on the arms are noted. His medical history includes asthma, for which he takes inhalers.
Given the likely diagnosis, which of the following treatments should he be started on?Your Answer: Topical clotrimazole
Correct Answer: Daily sunscreen to the affected areas
Explanation:Managing Vitiligo: Recommended Treatments and Precautions
Vitiligo is a skin condition that requires careful management to prevent further damage and reduce the risk of skin cancer. Daily application of sunscreen to affected areas is crucial due to increased susceptibility to UV-light-induced damage. Camouflaging makeup can also help alleviate psychological distress. Topical steroids are recommended for up to two months, and if there is no response, a referral to a dermatologist is necessary. Emollients and oral antihistamines are not useful in vitiligo management. Oral steroids are rarely used, and topical clotrimazole and dapsone are not first-line treatments. Topical tacrolimus and phototherapy may have a role, but caution is needed for light-skinned patients. Overall, early intervention and precautionary measures are key to managing vitiligo effectively.
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This question is part of the following fields:
- Dermatology
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Question 12
Incorrect
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A 50-year-old woman comes to the clinic complaining of an itchy papular rash on her palms and forearms. The rash has white lines visible across its surface and scratching has worsened it. Additionally, she has noticed thinning of her nails with longitudinal ridges visible. What is the most appropriate first-line treatment?
Your Answer: Emollients
Correct Answer: Potent topical steroids
Explanation:The primary treatment for lichen planus is potent topical steroids. Emollients are not effective for this condition, and oral steroids may only be necessary in severe or resistant cases. Calcipotriol, a synthetic vitamin D derivative, is used for psoriasis and not lichen planus. Fusidic acid is an antibiotic used for staphylococcal skin infections, such as impetigo, and is not indicated for lichen planus.
Understanding Lichen Planus
Lichen planus is a skin condition that is believed to be caused by an immune response, although the exact cause is unknown. It is characterized by an itchy, papular rash that typically appears on the palms, soles, genitalia, and flexor surfaces of the arms. The rash often has a polygonal shape and a distinctive white-lines pattern on the surface, known as Wickham’s striae. In some cases, new skin lesions may appear at the site of trauma, a phenomenon known as the Koebner phenomenon.
Oral involvement is common in around 50% of patients, with a white-lace pattern often appearing on the buccal mucosa. Nail changes may also occur, including thinning of the nail plate and longitudinal ridging. Lichenoid drug eruptions can be caused by certain medications, such as gold, quinine, and thiazides.
The main treatment for lichen planus is potent topical steroids. For oral lichen planus, benzydamine mouthwash or spray is recommended. In more extensive cases, oral steroids or immunosuppression may be necessary.
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This question is part of the following fields:
- Dermatology
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Question 13
Incorrect
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Which one of the following statements regarding scabies is untrue?
Your Answer: Typically affects the fingers, interdigital webs and flexor aspects of the wrist in adults
Correct Answer: Patients who complain of pruritus 4 weeks following treatment should be retreated
Explanation:It is typical for itching to continue for a period of 4-6 weeks after elimination.
Scabies: Causes, Symptoms, and Treatment
Scabies is a skin condition caused by the Sarcoptes scabiei mite, which is spread through prolonged skin contact. It is most commonly seen in children and young adults. The mite burrows into the skin and lays its eggs in the stratum corneum, leading to intense itching. This itching is caused by a delayed-type IV hypersensitivity reaction to the mites/eggs, which occurs about 30 days after the initial infection. Symptoms of scabies include widespread itching, linear burrows on the fingers, interdigital webs, and flexor aspects of the wrist. In infants, the face and scalp may also be affected. Scratching can lead to secondary features such as excoriation and infection.
The first-line treatment for scabies is permethrin 5%, while malathion 0.5% is second-line. Patients should be advised to avoid close physical contact with others until treatment is complete. All household and close physical contacts should be treated at the same time, even if asymptomatic. Clothing, bedding, and towels should be laundered, ironed, or tumble-dried on the first day of treatment to kill off mites. The insecticide should be applied to all areas, including the face and scalp, contrary to the manufacturer’s recommendation. Patients should apply the insecticide cream or liquid to cool, dry skin, paying close attention to areas between fingers and toes, under nails, armpit area, and creases of the skin such as at the wrist and elbow. The insecticide should be left on the skin for 8-12 hours for permethrin or 24 hours for malathion before washing off. Treatment should be repeated 7 days later.
Crusted scabies, also known as Norwegian scabies, is seen in patients with suppressed immunity, especially HIV. The crusted skin will be teeming with hundreds of thousands of organisms. Isolation is essential, and ivermectin is the treatment of choice.
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This question is part of the following fields:
- Dermatology
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Question 14
Correct
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A 32-year-old woman presents with worries about hair loss. She reports experiencing hair loss in small patches on her scalp. During examination, you observe distinct patches of hair loss with some ‘broken exclamation mark’ hairs at the edges.
What is the most probable diagnosis?Your Answer: Alopecia areata
Explanation:Understanding Hair Loss: Causes and Symptoms
Hair loss is a common concern for many individuals, causing anxiety and worry. There are various causes of hair loss, each with their own unique symptoms. Alopecia areata is a chronic inflammatory disease that affects the hair follicles, resulting in patchy, non-scarring hair loss on the scalp. Androgenic alopecia, on the other hand, is more common in men and causes a receding hairline and loss of hair from the top and front of the head. Fungal infections, such as tinea capitis, can also cause hair loss accompanied by scaling, itching, and pain. Scalp psoriasis can range from mild scaling to severe crusted plaques covering the entire scalp, while erosive pustular dermatosis of the scalp affects elderly individuals with scarring and yellow-brown crusts. It is important to understand the various causes and symptoms of hair loss in order to properly diagnose and treat the condition.
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This question is part of the following fields:
- Dermatology
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Question 15
Correct
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A 60-year-old man presents to his primary care physician with a chief complaint of severe itching following his shower. The patient reports that this has been ongoing for approximately two months and has not improved. His medical history is significant for a previous deep vein thrombosis in his left leg three years ago and an episode of gout in his right hallux six years ago. What is the most probable diagnosis for this patient?
Your Answer: Polycythaemia vera
Explanation:Understanding Polycythaemia: Types and Causes
Polycythaemia is a condition characterized by an increase in the number of red blood cells in the body. There are three types of polycythaemia: relative, primary, and secondary. Relative polycythaemia is caused by factors such as dehydration and stress, while primary polycythaemia rubra vera is a rare blood disorder that results in the overproduction of red blood cells. Secondary polycythaemia, on the other hand, is caused by underlying medical conditions such as COPD, altitude, and obstructive sleep apnoea.
To differentiate between true polycythaemia and relative polycythaemia, red cell mass studies are sometimes used. In true polycythaemia, the total red cell mass in males is greater than 35 ml/kg and in women, it is greater than 32 ml/kg. It is important to identify the underlying cause of polycythaemia to determine the appropriate treatment plan. While polycythaemia is rarely a clinical problem, it is essential to monitor the condition to prevent complications.
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This question is part of the following fields:
- Dermatology
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Question 16
Incorrect
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Which one of the following is not a management option for individuals with hyperhidrosis?
Your Answer: Botulinum toxin
Correct Answer: Topical atropine
Explanation:Hyperhidrosis is a condition characterized by the excessive production of sweat. To manage this condition, there are several options available. The first-line treatment is the use of topical aluminium chloride preparations, although it may cause skin irritation as a side effect. Iontophoresis is another option that is particularly useful for patients with palmar, plantar, and axillary hyperhidrosis. Botulinum toxin is also licensed for axillary symptoms. Surgery, such as Endoscopic transthoracic sympathectomy, is another option, but patients should be informed of the risk of compensatory sweating. Overall, there are various management options available for hyperhidrosis, and patients should discuss with their healthcare provider to determine the best course of action.
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This question is part of the following fields:
- Dermatology
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Question 17
Correct
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A 35-year-old office worker complains of widespread pruritus for the last 2 weeks. She has no particular history of note, though she is currently staying with her parents due to financial difficulties. She has noticed the itching is particularly bad at night. On examination, she has several circular erythematous lesions on her arms and legs.
Given the likely diagnosis, what is the most appropriate first-line treatment option?Your Answer: Permethrin cream applied from neck down for 8-14 hours
Explanation:Treatment Options for Scabies Infestation
Scabies infestation is a common condition that can affect anyone, but those with poor personal hygiene, immunocompromisation, low socioeconomic status, and those working in industrial settings are at higher risk. The first-line treatment for scabies is the application of Permethrin 5% cream from the neck down for 8-14 hours, followed by washing it off. It is important to treat all household contacts simultaneously, even if they are symptom-free. Additionally, all affected linens should be washed and cleaned immediately.
While 5% Hydrocortisone cream can be applied twice daily to relieve itching, it will not treat the underlying infestation. Similarly, emollient cream can be applied regularly to moisturize the skin, but it will not treat the infestation.
If Permethrin is not effective, Malathion cream can be used as a second-line treatment. It should be applied from the neck down for 24 hours and then washed off.
Oral antihistamines can be used to treat the symptomatic itch, but they do not address the underlying infestation. Therefore, it is important to follow the recommended treatment plan and seek medical advice if symptoms persist.
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This question is part of the following fields:
- Dermatology
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Question 18
Incorrect
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A 28-year-old woman presents with a recurring, intensely itchy rash on the palms of her hands. She reports that these rashes tend to occur every summer. Despite trying over-the-counter emollients and antihistamines, there has been only marginal improvement. The patient is otherwise healthy with no other medical conditions and does not smoke.
During examination, bilateral vesicles are observed on the palms and sides of the fingers. The palms appear dry with areas of skin peeling, while the rest of her body is unaffected.
What is the most probable diagnosis?Your Answer: Keratoderma blennorhagicum
Correct Answer: Pompholyx eczema
Explanation:Palmoplantar pustulosis is often accompanied by psoriasis on other areas of the body and is strongly linked to smoking. Unlike pompholyx eczema, the connection to high temperatures and humidity is not as significant. Scabies, which is caused by the parasite Sarcoptes scabiei, results in severe itching of the hands and web spaces but is typically not a recurring issue. Symptoms include linear burrows and erythematous papules rather than vesicles.
Understanding Pompholyx Eczema
Pompholyx eczema, also known as dyshidrotic eczema, is a type of skin condition that affects both the hands and feet. It is often triggered by high temperatures and humidity, such as sweating. The main symptom of pompholyx eczema is the appearance of small blisters on the palms and soles, which can be intensely itchy and sometimes accompanied by a burning sensation. Once the blisters burst, the skin may become dry and crack.
To manage pompholyx eczema, cool compresses and emollients can be used to soothe the affected areas. Topical steroids may also be prescribed to reduce inflammation and itching. It is important to avoid further irritation by wearing gloves or protective footwear and avoiding exposure to irritants. With proper management, the symptoms of pompholyx eczema can be controlled and minimized.
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This question is part of the following fields:
- Dermatology
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Question 19
Incorrect
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A 28-year-old man with psoriasis affecting the scalp and legs visits his General Practitioner with ongoing symptoms despite using once-daily Betnovate® (a potent steroid) and a vitamin D analogue for six weeks.
What should be the next course of action in managing this patient?Your Answer: Refer to Dermatology
Correct Answer: Stop steroid treatment and continue vitamin D analogue twice daily
Explanation:Psoriasis management follows a stepwise approach, as per NICE guidelines. In this case, the patient has already received eight weeks of potent steroid with a vitamin D analogue. The next step is to stop the steroid and increase the vitamin D analogue to twice daily. Steroids should not be used at the same site for more than eight weeks, and patients require a 4-week steroid-free break. If symptoms persist, twice-daily steroids or a coal tar preparation can be tried. Referral to Dermatology may be necessary for severe cases, but starting the next stage of treatment while awaiting review is appropriate. An ultra-potent steroid may be considered after the steroid-free break or as a short course if necessary.
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This question is part of the following fields:
- Dermatology
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Question 20
Incorrect
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A 47-year-old woman was prescribed carbamazepine for trigeminal neuralgia. After a few days, she experiences a prodromal illness with symptoms of sore throat, malaise, and conjunctivitis. She then develops a rash that initially presents as erythematous macules on her torso and progresses to blisters, covering less than 10% of her body surface area. Additionally, she has painful ulcers in her mouth, stomatitis, and worsening conjunctivitis. What is the probable diagnosis?
Your Answer: Erythema multiforme minor
Correct Answer: Stevens-Johnson syndrome
Explanation:Erythema multiforme is a skin condition that is characterized by a rash that affects a small area of the body or the entire body surface. It can be caused by drugs or other factors. The exact cause of this condition is unknown. The rash typically appears on the hands and feet and is often raised. In some cases, the rash may also affect the mucous membranes. This is known as the major form of erythema multiforme.
Understanding Stevens-Johnson Syndrome
Stevens-Johnson syndrome is a severe reaction that affects both the skin and mucosa. It is usually caused by a drug reaction and is considered a separate entity from erythema multiforme. Common causes of Stevens-Johnson syndrome include penicillin, sulphonamides, lamotrigine, carbamazepine, phenytoin, allopurinol, NSAIDs, and oral contraceptive pills. The rash associated with this syndrome is typically maculopapular with target lesions, which may develop into vesicles or bullae. A positive Nikolsky sign is observed in erythematous areas, where blisters and erosions appear when the skin is gently rubbed. Mucosal involvement and systemic symptoms such as fever and arthralgia may also occur. Hospital admission is required for supportive treatment.
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This question is part of the following fields:
- Dermatology
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Question 21
Incorrect
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A 72-year-old male presents to his primary care clinic with a 3-day history of burning pain and rash on the right side of his chest. He also complains of feeling generally unwell. He has no significant medical history and is not taking any regular medications.
During the physical examination, an erythematous rash with multiple clear vesicles is observed on the right side of the torso. The remainder of the clinical examination, including an ophthalmic examination, is unremarkable.
What is the most appropriate initial management for this patient's most likely diagnosis?Your Answer: Prescribe intravenous aciclovir
Correct Answer: Prescribe oral famciclovir
Explanation:Patients suspected of having shingles should receive antiviral treatment within 72 hours of symptom onset, according to NICE guidelines. Shingles is diagnosed based on the presence of dermatomal pain and a papular rash, with pain often persisting after the rash has resolved. The recommended first-line oral antivirals are famciclovir or valacyclovir, to be taken for 7 days. Aciclovir is a second-line option, as studies have shown that famciclovir and valacyclovir are more effective in reducing the risk of postherpetic pain. Prescribing calamine lotion and analgesia, as well as monitoring the patient, is not sufficient and does not replace antiviral treatment. Intravenous antivirals are only necessary if the patient cannot tolerate oral medication, and famciclovir cannot be administered intravenously.
Shingles is a painful blistering rash caused by reactivation of the varicella-zoster virus. It is more common in older individuals and those with immunosuppressive conditions. The rash is well demarcated by the affected dermatome and may be accompanied by fever and lethargy. Treatment includes analgesia, antivirals, and potentially oral corticosteroids. Complications include post-herpetic neuralgia, ocular and ear complications. Antivirals should be used within 72 hours to reduce the risk of post-herpetic neuralgia.
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This question is part of the following fields:
- Dermatology
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Question 22
Correct
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A 28-year-old man who is HIV positive has been diagnosed with seborrhoeic dermatitis. What are the two most commonly associated complications with this condition?
Your Answer: Blepharitis and otitis externa
Explanation:Seborrhoeic dermatitis often leads to otitis externa and blepharitis as complications. Although rare, alopecia may occur if a severe secondary infection develops.
Understanding Seborrhoeic Dermatitis in Adults
Seborrhoeic dermatitis is a chronic skin condition that affects around 2% of the general population. It is caused by an inflammatory reaction related to the overgrowth of a fungus called Malassezia furfur, which is a normal inhabitant of the skin. The condition is characterized by eczematous lesions that appear on the sebum-rich areas of the body, such as the scalp, periorbital, auricular, and nasolabial folds. It can also lead to the development of otitis externa and blepharitis.
Seborrhoeic dermatitis is often associated with other medical conditions, such as HIV and Parkinson’s disease. The management of the condition depends on the affected area. For scalp disease, over-the-counter preparations containing zinc pyrithione and tar are usually the first-line treatment. If these are not effective, ketoconazole is the preferred second-line agent. Selenium sulphide and topical corticosteroids may also be useful.
For the face and body, topical antifungals such as ketoconazole and topical steroids are often used. However, it is important to use steroids for short periods only to avoid side effects. Seborrhoeic dermatitis can be difficult to treat, and recurrences are common. Therefore, it is important to work closely with a healthcare provider to manage the condition effectively.
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This question is part of the following fields:
- Dermatology
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Question 23
Correct
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A 20-year-old individual comes in with a 1 cm golden, crusted lesion on the border of their left lower lip. They have previously tried topical hydrogen peroxide for a similar episode without success. What is the best course of action for management?
Your Answer: Topical fusidic acid
Explanation:If hydrogen peroxide is not appropriate, topical fusidic acid can be used for impetigo.
Understanding Impetigo: Causes, Symptoms, and Management
Impetigo is a common bacterial skin infection that affects both children and adults. It is caused by either Staphylococcus aureus or Streptococcus pyogenes and can develop anywhere on the body, but lesions tend to occur on the face, flexures, and limbs not covered by clothing. The infection can be a primary infection or a complication of an existing skin condition such as eczema, scabies, or insect bites. Impetigo is highly contagious and can spread through direct contact with discharges from the scabs of an infected person or indirectly through toys, clothing, equipment, and the environment.
The symptoms of impetigo include ‘golden’, crusted skin lesions typically found around the mouth. The infection can be managed with limited, localized disease by using hydrogen peroxide 1% cream or topical antibiotic creams such as fusidic acid or mupirocin. However, if the disease is extensive, oral flucloxacillin or oral erythromycin may be prescribed. It is important to note that MRSA is not susceptible to either fusidic acid or retapamulin, so topical mupirocin should be used in this situation.
Children with impetigo should be excluded from school until the lesions are crusted and healed or 48 hours after commencing antibiotic treatment. It is also important to practice good hygiene, such as washing hands regularly and avoiding close contact with infected individuals, to prevent the spread of impetigo. By understanding the causes, symptoms, and management of impetigo, individuals can take steps to prevent and treat this common bacterial skin infection.
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This question is part of the following fields:
- Dermatology
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Question 24
Correct
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You are conducting an 8-week examination on a baby with a prominent purplish birthmark. The mother was informed that it may not disappear on its own and could be linked to other vascular issues. What is the probable diagnosis?
Your Answer: Port wine stain
Explanation:Understanding Port Wine Stains
Port wine stains are a type of birthmark that are characterized by their deep red or purple color. Unlike other vascular birthmarks, such as salmon patches and strawberry hemangiomas, port wine stains do not go away on their own and may even become more prominent over time. These birthmarks are typically unilateral, meaning they only appear on one side of the body.
Fortunately, there are treatment options available for those who wish to reduce the appearance of port wine stains. Cosmetic camouflage can be used to cover up the birthmark, while laser therapy is another option that requires multiple sessions. It’s important to note that while these treatments can help reduce the appearance of port wine stains, they may not completely eliminate them. Understanding the nature of port wine stains and the available treatment options can help individuals make informed decisions about managing these birthmarks.
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This question is part of the following fields:
- Dermatology
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Question 25
Incorrect
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A father brings his 4-year-old daughter to see her General Practitioner with a rash covering her face, trunk, arms and legs. She had a fever for a couple of days with a runny nose before the rash appears but is now well and afebrile. The rash is mainly vesicular with small fluid-filled blisters and there are a few scabbed lesions. Her father is concerned as she is scratching the lesions, especially at night. She is otherwise fit and well and is up-to-date with her vaccinations.
Which of the following is the most appropriate treatment?Your Answer: Aciclovir
Correct Answer: Chlorphenamine
Explanation:Treatment Options for chickenpox in Children
chickenpox is a common viral infection in children that presents with a characteristic vesicular rash. While there is no specific treatment for chickenpox, symptomatic relief can be provided to alleviate itching and fever. Here are some treatment options for chickenpox in children:
1. Chlorphenamine: This sedating antihistamine can be used at night-time to help with itching.
2. Aciclovir: This antiviral medication is recommended for patients who are immunosuppressed or have risk factors for developing complications from infection, such as adults or newborns.
3. Flucloxacillin: This antibiotic is used to treat secondary bacterial infections that can occur with chickenpox. However, it is not necessary for a child who is well and afebrile.
4. Ibuprofen: While ibuprofen and paracetamol are both used as antipyretics in children with febrile illnesses, the use of ibuprofen in children with chickenpox is linked to an increased risk of severe skin infection. Paracetamol is recommended instead.
5. Malathion: This treatment is for scabies, not chickenpox. Scabies presents with a different type of rash and does not have a prodromal illness.
In summary, treatment for chickenpox in children is mainly symptomatic. Antihistamines and calamine lotion can help with itching, while paracetamol can be used for fever. Antibiotics and antivirals are only necessary in certain cases.
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This question is part of the following fields:
- Dermatology
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Question 26
Correct
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A 42-year-old man comes in with an ongoing itchy rash that has been present for a few weeks. During examination, he displays erythematous, scaly lesions beneath his eyebrows, around his nose, and at the top of his chest. He also has a history of dandruff that he manages well with over-the-counter shampoos. What is the best course of treatment for the lesions on his face and trunk?
Your Answer: Topical ketoconazole
Explanation:Seborrhoeic dermatitis is typically characterized by a scaly rash around the peri-orbital and nasolabial areas, as well as dandruff. The recommended initial treatment is topical ketoconazole.
Understanding Seborrhoeic Dermatitis in Adults
Seborrhoeic dermatitis is a chronic skin condition that affects around 2% of the general population. It is caused by an inflammatory reaction related to the overgrowth of a fungus called Malassezia furfur, which is a normal inhabitant of the skin. The condition is characterized by eczematous lesions that appear on the sebum-rich areas of the body, such as the scalp, periorbital, auricular, and nasolabial folds. It can also lead to the development of otitis externa and blepharitis.
Seborrhoeic dermatitis is often associated with other medical conditions, such as HIV and Parkinson’s disease. The management of the condition depends on the affected area. For scalp disease, over-the-counter preparations containing zinc pyrithione and tar are usually the first-line treatment. If these are not effective, ketoconazole is the preferred second-line agent. Selenium sulphide and topical corticosteroids may also be useful.
For the face and body, topical antifungals such as ketoconazole and topical steroids are often used. However, it is important to use steroids for short periods only to avoid side effects. Seborrhoeic dermatitis can be difficult to treat, and recurrences are common. Therefore, it is important to work closely with a healthcare provider to manage the condition effectively.
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This question is part of the following fields:
- Dermatology
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Question 27
Incorrect
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A 55-year-old man complains of persistent itching caused by shiny, flat-topped papules on the palmar aspect of his wrists. Lichen planus is suspected. What is the best course of treatment?
Your Answer: Topical clotrimazole
Correct Answer: Topical clobetasone butyrate
Explanation:Understanding Lichen Planus
Lichen planus is a skin condition that is believed to be caused by an immune response, although the exact cause is unknown. It is characterized by an itchy, papular rash that typically appears on the palms, soles, genitalia, and flexor surfaces of the arms. The rash often has a polygonal shape and a distinctive white-lines pattern on the surface, known as Wickham’s striae. In some cases, new skin lesions may appear at the site of trauma, a phenomenon known as the Koebner phenomenon.
Oral involvement is common in around 50% of patients, with a white-lace pattern often appearing on the buccal mucosa. Nail changes may also occur, including thinning of the nail plate and longitudinal ridging. Lichenoid drug eruptions can be caused by certain medications, such as gold, quinine, and thiazides.
The main treatment for lichen planus is potent topical steroids. For oral lichen planus, benzydamine mouthwash or spray is recommended. In more extensive cases, oral steroids or immunosuppression may be necessary.
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This question is part of the following fields:
- Dermatology
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Question 28
Incorrect
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A 16-year-old female from Nigeria comes to the clinic with a swelling near her earlobe. She had her ears pierced three months ago and has noticed a gradual development of an erythematous swelling. Upon examination, a keloid scar is observed. What is the best course of action for management?
Your Answer: Refer for intralesional sclerotherapy
Correct Answer: Refer for intralesional triamcinolone
Explanation:Understanding Keloid Scars
Keloid scars are abnormal growths that develop from the connective tissue of a scar and extend beyond the boundaries of the original wound. They are more common in people with dark skin and tend to occur in young adults. Keloids are most frequently found on the sternum, shoulder, neck, face, extensor surface of limbs, and trunk.
To prevent keloid scars, incisions should be made along relaxed skin tension lines. However, if keloids do develop, early treatment with intra-lesional steroids such as triamcinolone may be effective. In some cases, excision may be necessary, but this should be approached with caution as it can potentially lead to further keloid scarring.
It is important to note that the historical use of Langer lines to determine optimal incision lines has been shown to produce worse cosmetic results than following skin tension lines. Understanding the predisposing factors and treatment options for keloid scars can help individuals make informed decisions about their care.
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This question is part of the following fields:
- Dermatology
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Question 29
Incorrect
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A 35-year-old woman with a history of eczema and Crohn's disease presents with a pruritic, red rash in the right and left popliteal regions. She works as a nurse and frequently scratches the back of her knees while on duty. This is the third time she has experienced such a popliteal rash. She reports having had similar skin conditions affecting her posterior neck and inguinal areas in the past.
Upon examination, both popliteal areas are inflamed with mild swelling and exudation. There are some accompanying vesicles and papules.
What is the most probable diagnosis?Your Answer: Seborrhoeic dermatitis
Correct Answer: Atopic dermatitis
Explanation:Dermatological Conditions and Their Distribution: Understanding the Diagnosis
When it comes to diagnosing skin conditions, the location and distribution of the rash or lesion are just as important as their appearance. For instance, a rash in the flexural regions of an adult patient, such as the popliteal region, is likely to be atopic dermatitis, especially if the patient has a history of asthma. Acute dermatitis typically presents with erythema, oedema, vesicles, and papules.
On the other hand, dermatitis herpetiformis, which is often associated with coeliac disease and malabsorption, presents with grouped vesicles and papules over the extensor surfaces of the elbows, knees, upper back, and buttocks. A rash limited to the popliteal region is unlikely to be dermatitis herpetiformis.
Lichen planus, characterized by flat-topped, pruritic, polygonal, red-to-violaceous papules or plaques, is mostly found on the wrists, ankles, or genitalia. Psoriasis, which presents with silvery, scaling, erythematous plaques, is primarily found on the extensor surfaces. Seborrhoeic dermatitis, which is found in the distribution of the sebaceous glands, such as the nasolabial folds, scalp, eyebrows, genitalia, and presternal regions, is unlikely to be the cause of a rash limited to the popliteal region.
In summary, understanding the distribution and location of skin lesions is crucial in making an accurate diagnosis of dermatological conditions.
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This question is part of the following fields:
- Dermatology
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Question 30
Incorrect
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A 4-year-old boy is brought to the doctor's office because of a rash on his upper arm. During the examination, the doctor observes several raised lesions that are approximately 2 mm in diameter. Upon closer inspection, a central dimple is visible in most of the lesions. What is the probable diagnosis?
Your Answer: Roseola infantum
Correct Answer: Molluscum contagiosum
Explanation:Understanding Molluscum Contagiosum
Molluscum contagiosum is a viral skin infection that is commonly seen in children, particularly those with atopic eczema. It is caused by the molluscum contagiosum virus and can be transmitted through direct contact or contaminated surfaces. The infection presents as pinkish or pearly white papules with a central umbilication, which can appear anywhere on the body except for the palms of the hands and soles of the feet. In children, lesions are commonly seen on the trunk and in flexures, while in adults, sexual contact may lead to lesions developing on the genitalia, pubis, thighs, and lower abdomen.
While molluscum contagiosum is a self-limiting condition that usually resolves within 18 months, it is important to avoid sharing towels, clothing, and baths with uninfected individuals to prevent transmission. Scratching the lesions should also be avoided, and treatment may be considered if the itch is problematic. However, treatment is not usually recommended, and if necessary, simple trauma or cryotherapy may be used. In some cases, referral may be necessary, such as for individuals who are HIV-positive with extensive lesions or those with eyelid-margin or ocular lesions and associated red eye.
Overall, understanding molluscum contagiosum and taking appropriate precautions can help prevent transmission and alleviate symptoms.
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This question is part of the following fields:
- Dermatology
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