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Question 1
Correct
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A 27-year-old individual diagnosed with schizophrenia has a history of cannabis misuse and has discontinued their medication. They are currently experiencing auditory hallucinations where multiple voices are conversing about them. The voices are making derogatory comments, accusing the individual of being a paedophile and deserving punishment.
What is the best description of this hallucination?Your Answer: Third person hallucination
Explanation:Types of Auditory Hallucinations
There are different types of auditory hallucinations that individuals may experience. One type is third person hallucinations, where patients hear voices talking about them in the third person. This is considered a first rank symptom of schizophrenia, but it can also occur in other psychiatric disorders such as mania. Another type is extra-campine hallucinations, which are perceived as coming from outside of the normal sensory field, such as from several miles away. Functional hallucinations, on the other hand, are triggered by stimuli within the same sensory field, such as hearing a phone ring that triggers a voice. Lastly, imperative hallucinations involve the auditory hallucination giving instructions to the patient.
the Different Types of Auditory Hallucinations
Auditory hallucinations can be a distressing experience for individuals who hear voices that are not there. It is important to note that there are different types of auditory hallucinations, each with their own unique characteristics. Third person hallucinations involve hearing voices talking about the individual in the third person, while extra-campine hallucinations are perceived as coming from outside of the normal sensory field. Functional hallucinations are triggered by stimuli within the same sensory field, and imperative hallucinations involve the auditory hallucination giving instructions to the patient. the different types of auditory hallucinations can help individuals and healthcare professionals better identify and manage these experiences.
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This question is part of the following fields:
- Psychiatry
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Question 2
Correct
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A 68-year-old man is brought to the Emergency Department on Thursday evening after falling and hitting his head on the pavement. He was found to be heavily intoxicated and unable to stand. A CT scan of his head reveals a crescent-shaped hematoma on the right side. The patient undergoes a burr-hole craniostomy with irrigation, which goes smoothly. However, two days later, the nursing staff notices that he is restless and agitated. He is speaking to his deceased wife, who passed away 15 years ago, and does not recognize any of the nurses. Additionally, he has developed hand tremors.
What medication has been overlooked by the medical team caring for this patient?Your Answer: Chlordiazepoxide
Explanation:Long-acting benzodiazepines are administered in decreasing doses to manage alcohol withdrawal symptoms in patients with a history of alcohol abuse. A man with such a history presents with anxiety, restlessness, visual and auditory hallucinations, and tremors 48 hours after his last alcohol intake. Chlordiazepoxide, a benzodiazepine, is prescribed to alleviate acute alcohol withdrawal and anxiety. Mannitol is indicated for cerebral edema, furosemide is a diuretic, and escitalopram is commonly used to treat anxiety and depression.
Alcohol withdrawal occurs when an individual who has been consuming alcohol chronically suddenly stops or reduces their intake. This is due to the fact that chronic alcohol consumption enhances GABA-mediated inhibition in the central nervous system (CNS), similar to benzodiazepines, and inhibits NMDA-type glutamate receptors. When alcohol consumption is stopped, the opposite occurs, resulting in decreased inhibitory GABA and increased NMDA glutamate transmission.
Symptoms of alcohol withdrawal typically start within 6-12 hours and include tremors, sweating, tachycardia, and anxiety. Seizures are most likely to occur at around 36 hours, while delirium tremens, which is characterized by coarse tremors, confusion, delusions, auditory and visual hallucinations, fever, and tachycardia, is most likely to occur at around 48-72 hours.
Patients with a history of complex withdrawals from alcohol, such as delirium tremens, seizures, or blackouts, should be admitted to the hospital for monitoring until their withdrawals stabilize. The first-line treatment for alcohol withdrawal is long-acting benzodiazepines, such as chlordiazepoxide or diazepam, which are typically given as part of a reducing dose protocol. Lorazepam may be preferable in patients with hepatic failure. Carbamazepine is also effective in treating alcohol withdrawal, while phenytoin is said not to be as effective in the treatment of alcohol withdrawal seizures.
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This question is part of the following fields:
- Psychiatry
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Question 3
Correct
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What type of hallucination is Lillian experiencing while being unwell in bed with pneumonia and seeing a tiny marching band on her bedclothes?
Your Answer: Visual hallucination - Lilliputian hallucinations
Explanation:Types of Hallucinations
Hallucinations are false perceptions that occur simultaneously with real perceptions. There are different types of hallucinations, including visual hallucinations associated with micropsia, which are known as Lilliputian hallucinations. These hallucinations often occur in patients suffering from delirium. Another type of visual hallucination is elementary hallucinations, which appear as flashes of light.
Extracampine hallucinations occur when an individual experiences a hallucination outside their sensory field, such as seeing someone standing behind them while looking straight ahead. Reflex hallucinations happen when a true sensory stimulus causes a hallucination in another sensory modality. Lastly, autoscopy is the experience of seeing oneself and knowing it is oneself, also known as the phantom mirror-image. the different types of hallucinations can help in identifying and treating them appropriately.
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This question is part of the following fields:
- Psychiatry
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Question 4
Correct
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A woman punishes her 10-year-old son for breaking his younger sibling's toy by removing one of his favourite toys from the shelf. Her son becomes tearful and wets his bed. He was a previously toilet-trained child.
Which ego defence mechanism is demonstrated by the 10-year-old's behaviour of wetting his bed after being punished for breaking his sibling's toy?Your Answer: Regression
Explanation:Regression refers to the involuntary process of reverting back to earlier ways of dealing with the world, which is different from fixation. This phenomenon is commonly observed in children who are experiencing stress due to factors such as illness, punishment, or the arrival of a new sibling. For instance, a child who was previously toilet-trained may start bedwetting again under such circumstances. Other related psychological concepts include reaction formation, fixation, and displacement.
Understanding Ego Defenses
Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.
Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.
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This question is part of the following fields:
- Psychiatry
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Question 5
Incorrect
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A man in his early forties, who has a background of bipolar disorder, arrives with a fever and pneumonia that is advancing quickly. Upon conducting blood tests, it is discovered that he has neutropenia. Which medication is the most probable cause of this?
Your Answer: Lithium
Correct Answer: Clozapine
Explanation:Clozapine can cause a life-threatening condition called agranulocytosis/neutropenia, which requires monitoring of the patient’s full blood count. On the other hand, olanzapine may lead to weight gain and type 2 diabetes, while lithium can cause symptoms such as nausea, diarrhea, dizziness, muscle weakness, fatigue, tremors, polyuria, polydipsia, and weight gain. Sodium valproate, on the other hand, can cause increased appetite and weight, liver failure, pancreatitis, reversible hair loss that grows back curly, edema, ataxia, teratogenicity, tremors, thrombocytopenia, and encephalopathy due to hyperammonemia. Lastly, carbamazepine may cause drowsiness, leukopenia, diplopia, blurred vision, and rash.
Atypical antipsychotics are now recommended as the first-line treatment for patients with schizophrenia, as per the 2005 NICE guidelines. These agents have a significant advantage over traditional antipsychotics in that they cause fewer extrapyramidal side-effects. However, atypical antipsychotics can still cause adverse effects such as weight gain, hyperprolactinaemia, and clozapine-associated agranulocytosis. Elderly patients who take antipsychotics are at an increased risk of stroke and venous thromboembolism, according to the Medicines and Healthcare products Regulatory Agency.
Clozapine is one of the first atypical antipsychotics to be developed, but it carries a significant risk of agranulocytosis. Therefore, full blood count monitoring is essential during treatment. Clozapine should only be used in patients who are resistant to other antipsychotic medication. The BNF recommends introducing clozapine if schizophrenia is not controlled despite the sequential use of two or more antipsychotic drugs, one of which should be a second-generation antipsychotic drug, each for at least 6-8 weeks. Clozapine can cause adverse effects such as reduced seizure threshold, constipation, myocarditis, and hypersalivation. Dose adjustment of clozapine may be necessary if smoking is started or stopped during treatment.
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This question is part of the following fields:
- Psychiatry
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Question 6
Correct
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A teenager presents with the belief that they can fly. This is likely to be a primary delusion.
Which of the following is most commonly associated with this symptom?Your Answer: Schizophrenia
Explanation:Primary delusions are unique in that they cannot be attributed to any previous psychopathological state, such as a mood disorder. Delusions are characterized by an unshakeable, false belief that is not accepted by others in the patient’s culture. The patient perceives no difference between a delusional belief and a true belief.
The correct answer is Schizophrenia, as primary delusions are often observed in this disorder and other psychotic disorders. In contrast, mania and severe depression are more likely to cause secondary delusions that are related to the patient’s underlying mood.
Anorexia nervosa typically does not involve true delusions, but it may involve over-valued ideas that the person becomes preoccupied with.
Understanding Psychosis: Symptoms and Associated Features
Psychosis is a term used to describe a person’s experience of perceiving things differently from those around them. This can manifest in a variety of ways, including hallucinations, delusions, thought disorganization, alogia, tangentiality, clanging, and word salad. These symptoms can be associated with agitation, aggression, neurocognitive impairment, depression, and thoughts of self-harm.
Psychotic symptoms can occur in a number of conditions, including schizophrenia, depression, bipolar disorder, puerperal psychosis, brief psychotic disorder, neurological conditions like Parkinson’s disease and Huntington’s disease, and as a result of prescribed drugs or certain illicit drugs like cannabis and phencyclidine.
The peak age of first-episode psychosis is around 15-30 years. It is important to understand the symptoms and associated features of psychosis in order to recognize and seek appropriate treatment for those experiencing these symptoms.
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This question is part of the following fields:
- Psychiatry
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Question 7
Correct
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A 26-year-old male accountant comes to the clinic complaining of weakness in his left arm and right leg. He reports experiencing high levels of stress at work and a recent breakup with his girlfriend. Interestingly, he appears to show little emotional reaction when discussing these events and his motor symptoms. Additionally, he is observed moving his affected limbs normally when he thinks no one is watching. How would you describe his presentation?
Your Answer: Belle indifference
Explanation:Belle Indifference in Conversion Disorder
Conversion disorder is a dissociative disorder that arises when emotional stress is transformed into physical health symptoms. One of the characteristic features of this disorder is belle indifference, which is the lack of emotional response to the severe physical disabilities that patients with conversion disorders present with. Although it is rarely seen nowadays, it is still included in the diagnostic criteria of this disorder.
Belle indifference is typically observed in conversion disorder and is a striking feature of this condition. EEG and MRI may confirm the physical disability, but the patient shows no emotional response to the symptoms. Hypochondriasis, on the other hand, is a condition where the patient believes they have a specific diagnosis, such as cancer. It is important to differentiate between these two conditions as they have different treatment approaches. the features of belle indifference in conversion disorder can aid in the diagnosis and management of this disorder.
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This question is part of the following fields:
- Psychiatry
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Question 8
Correct
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A patient with intricate mental health issues and multiple medications presents at the clinic with concerns about weight gain. Which of the following medications is probable to be the cause of this side effect?
Your Answer: Olanzapine
Explanation:Weight gain is a prevalent side effect of antipsychotics.
While antipsychotics are successful in treating schizophrenia, they often lead to weight gain and an increased likelihood of developing type 2 diabetes. The most rapid weight gain typically occurs within the first six months of starting antipsychotic treatment.
In particular, Olanzapine and Clozapine are associated with a high risk of weight gain. They stimulate appetite and result in overeating, as well as disrupt glucose regulation.
Schizophrenia management guidelines were published by NICE in 2009. The guidelines recommend that first-line treatment for schizophrenia should involve oral atypical antipsychotics. Additionally, cognitive behavioural therapy should be offered to all patients. It is important to pay close attention to cardiovascular risk-factor modification due to the high rates of cardiovascular disease in schizophrenic patients, which is linked to antipsychotic medication and high smoking rates. Therefore, healthcare professionals should take necessary measures to reduce the risk of cardiovascular disease in these patients.
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This question is part of the following fields:
- Psychiatry
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Question 9
Correct
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What are the personality disorders included in Cluster B (the 'dramatic' group) in the DSM?
Your Answer: Antisocial, borderline, histrionic, and narcissistic
Explanation:Classification of Psychiatric Disorders
Psychiatric disorders are often grouped together based on their similarities, which can be useful for research and classification purposes. The three main clusters are eccentric, dramatic, and fearful. The eccentric cluster includes paranoid, schizoid, and schizotypal disorders. The dramatic cluster includes borderline, narcissistic, antisocial, and histrionic disorders. The fearful cluster includes obsessive-compulsive, avoidant, and dependent disorders.
The classification of psychiatric disorders follows the operational criteria of either DSM or ICD. DSM-V, published by the American Psychiatric Association, is multi-axial and allows for assessment of the patient’s current mental state diagnosis, personality disorder and learning difficulties, any physical condition, psychosocial or environmental factors, and global assessment of functioning scale. On the other hand, ICD-10, published by the World Health Organization, is used widely in Europe and also includes a multi-axial approach. However, personality disorder is not differentiated from other mental state disorders in ICD. The three axes in ICD are current mental state diagnosis (including personality disorder), disabilities, and contextual factors.
In summary, the classification of psychiatric disorders is important for research and treatment purposes. The three main clusters of disorders are eccentric, dramatic, and fearful. DSM and ICD are the two main operational criteria used for classification, with DSM being multi-axial and including a global assessment of functioning scale, while ICD is also multi-axial but does not differentiate personality disorder from other mental state disorders.
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This question is part of the following fields:
- Psychiatry
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Question 10
Incorrect
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A 60-year-old male patient comes in for a routine colonoscopy. He had stage I colon cancer that was treated successfully ten years ago. During the discussion of his thoughts, concerns, and expectations, he mentions that he hasn't thought about the potential results until now and that worrying won't change anything.
What ego defense mechanism is he displaying?Your Answer: Denial
Correct Answer: Suppression
Explanation:Understanding Ego Defenses
Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.
Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.
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This question is part of the following fields:
- Psychiatry
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Question 11
Correct
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A 78-year-old male is admitted to your ward with community-acquired pneumonia. He has a history of Parkinson's disease for the past 6 years. The patient becomes increasingly agitated during his stay, and you notice that he is prescribed haloperidol for agitation. However, after receiving the medication, his Parkinson's symptoms worsen significantly. What is the likely mechanism of action of haloperidol?
Your Answer: Blocks dopamine receptors
Explanation:Haloperidol is a typical antipsychotic that works by blocking dopamine receptors in the brain. However, typical antipsychotics are known to have non-selective blockage of various dopamine receptors, leading to unwanted side effects such as parkinsonism. This is particularly problematic for individuals with Parkinson’s disease, as the depletion of dopaminergic neurons already present in the condition can be further exacerbated by the use of antipsychotics that block any remaining dopamine transmissions.
Antipsychotics are a type of medication used to treat schizophrenia, psychosis, mania, and agitation. They are divided into two categories: typical and atypical antipsychotics. The latter were developed to address the extrapyramidal side-effects associated with the first generation of typical antipsychotics. Typical antipsychotics work by blocking dopaminergic transmission in the mesolimbic pathways through dopamine D2 receptor antagonism. However, they are known to cause extrapyramidal side-effects such as Parkinsonism, acute dystonia, akathisia, and tardive dyskinesia. These side-effects can be managed with procyclidine. Other side-effects of typical antipsychotics include antimuscarinic effects, sedation, weight gain, raised prolactin, impaired glucose tolerance, neuroleptic malignant syndrome, reduced seizure threshold, and prolonged QT interval. The Medicines and Healthcare products Regulatory Agency has issued specific warnings when antipsychotics are used in elderly patients due to an increased risk of stroke and venous thromboembolism.
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This question is part of the following fields:
- Psychiatry
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Question 12
Correct
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A 42-year-old man is brought to the GP by his wife. She reports that his behaviour has become increasingly erratic and that he often appears to be listening to something that she cannot hear.
During the consultation, the GP notices that he keeps standing up and sitting down again. When questioned on these movements, the patient says, 'I can't help it, my neighbour is controlling my legs.'
What symptom is the patient experiencing?Your Answer: Passivity
Explanation:Passivity is the belief that one’s movements or sensations are controlled by an external force. Grandiose delusion is a false belief in one’s own superiority. Avolition is a decrease in motivation for purposeful activities. Catatonia is a state of unresponsiveness with repetitive movements or abnormal postures.
Schizophrenia: Symptoms and Features
Schizophrenia is a mental disorder that is characterized by a range of symptoms. One of the most prominent classifications of these symptoms is Schneider’s first rank symptoms. These symptoms can be divided into four categories: auditory hallucinations, thought disorders, passivity phenomena, and delusional perceptions. Auditory hallucinations can include hearing two or more voices discussing the patient in the third person, thought echo, or voices commenting on the patient’s behavior. Thought disorders can include thought insertion, thought withdrawal, and thought broadcasting. Passivity phenomena can include bodily sensations being controlled by external influence or experiences that are imposed on the individual or influenced by others. Delusional perceptions can involve a two-stage process where a normal object is perceived, and then there is a sudden intense delusional insight into the object’s meaning for the patient.
Other features of schizophrenia include impaired insight, incongruity/blunting of affect (inappropriate emotion for circumstances), decreased speech, neologisms (made-up words), catatonia, and negative symptoms such as anhedonia (inability to derive pleasure), alogia (poverty of speech), and avolition (poor motivation). It is important to note that not all individuals with schizophrenia will experience all of these symptoms, and the severity of symptoms can vary from person to person.
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This question is part of the following fields:
- Psychiatry
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Question 13
Correct
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Oliver takes medication for a heart condition. He notices that everything he sees appears to be tinged with yellow.
What term could be used to describe this symptom?Your Answer: Xanthopsia
Explanation:Types of Visual Perceptions and Distortions
Xanthopsia, chloropsia, and erythropsia are all types of visual perceptions that involve a predominant color. Xanthopsia, in particular, is often caused by digitalis toxicity. Autoscopy, on the other hand, is a type of visual hallucination where an individual sees themselves and knows it is them. Dysmegalopsia, micropsia, and macropsia all describe changes in the perceived shape or size of an object. Hyperaesthesia, meanwhile, refers to an increased intensity of sensation, which can be uncomfortable for some individuals. Lastly, pareidolia is a visual illusion where an individual perceives an image in an otherwise vague or obscure stimulus.
It is important to note that sensory distortions can occur in any sense modality, not just in vision. These types of perceptions and distortions can be caused by various factors, such as medication side effects, neurological conditions, or even psychological states. these phenomena can help individuals recognize and seek appropriate treatment if necessary.
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This question is part of the following fields:
- Psychiatry
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Question 14
Correct
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A 20-year-old woman is brought in by her family. They report that she has been isolating herself and has not left the house for a few months. They suspect that she is experiencing auditory hallucinations and has been refusing to eat, believing that the food is contaminated. What is the recommended initial treatment for her probable diagnosis?
Your Answer: Olanzapine
Explanation:Clozapine is typically reserved for patients who do not respond to other antipsychotic medications, as it has the potential to cause serious side effects. Based on the symptoms described in the scenario, the most likely diagnosis is schizophrenia, which is typically treated with antipsychotic medications such as Olanzapine. Sertraline is an SSRI commonly used for depression and anxiety, while Sodium Valproate is a mood stabilizer used in bipolar disorder and epilepsy.
Schizophrenia management guidelines were published by NICE in 2009. The guidelines recommend that first-line treatment for schizophrenia should involve oral atypical antipsychotics. Additionally, cognitive behavioural therapy should be offered to all patients. It is important to pay close attention to cardiovascular risk-factor modification due to the high rates of cardiovascular disease in schizophrenic patients, which is linked to antipsychotic medication and high smoking rates. Therefore, healthcare professionals should take necessary measures to reduce the risk of cardiovascular disease in these patients.
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This question is part of the following fields:
- Psychiatry
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Question 15
Correct
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A teenage boy is brought to the emergency department by his family after stating that his 'insides' have ceased functioning and that he is to blame for the Syrian refugee crisis. Upon examination, the physician observes that he appears depressed and speaks in a slow, monotone voice with minimal facial expressions. What is the probable diagnosis?
Your Answer: Psychotic depression
Explanation:These delusions are congruent with depression in terms of mood, as they are considered to be depressing delusions.
Screening and Assessment of Depression
Depression is a common mental health condition that affects many people worldwide. Screening and assessment are important steps in identifying and managing depression. The screening process involves asking two simple questions to determine if a person is experiencing symptoms of depression. If the answer is yes to either question, a more in-depth assessment is necessary.
Assessment tools such as the Hospital Anxiety and Depression (HAD) scale and the Patient Health Questionnaire (PHQ-9) are commonly used to assess the severity of depression. The HAD scale consists of 14 questions, seven for anxiety and seven for depression. Each item is scored from 0-3, producing a score out of 21 for both anxiety and depression. The PHQ-9 asks patients about nine different problems they may have experienced in the last two weeks, which can then be scored from 0-3. This tool also includes questions about thoughts of self-harm.
The DSM-IV criteria are used by NICE to grade depression. This criteria includes nine different symptoms, such as depressed mood, diminished interest or pleasure in activities, and feelings of worthlessness or guilt. The severity of depression can range from subthreshold depressive symptoms to severe depression with or without psychotic symptoms.
In conclusion, screening and assessment are crucial steps in identifying and managing depression. By using tools such as the HAD scale and PHQ-9, healthcare professionals can accurately assess the severity of depression and provide appropriate treatment.
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This question is part of the following fields:
- Psychiatry
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Question 16
Correct
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A 76-year-old patient is being treated by a nurse when he suddenly becomes very agitated and attempts to hit the nurse with his walking stick. Soon after, the physician on the ward arrives and administers a dose of lorazepam.
What potential adverse effect may occur in this patient after receiving lorazepam?Your Answer: Respiratory depression
Explanation:Respiratory depression is a known adverse effect of benzodiazepines, particularly when used in conjunction with other respiratory depressants like opioids. Symptoms of benzodiazepine withdrawal syndrome typically include tremors, anxiety, sweating, and seizures, but these are not considered adverse effects of benzodiazepine use.
Benzodiazepines are drugs that enhance the effect of the neurotransmitter GABA, which has an inhibitory effect on the brain. This makes them useful for a variety of purposes, including sedation, anxiety relief, muscle relaxation, and as anticonvulsants. However, patients can develop a tolerance and dependence on these drugs, so they should only be prescribed for short periods of time. When withdrawing from benzodiazepines, it is important to do so gradually, reducing the dose every few weeks. If patients withdraw too quickly, they may experience benzodiazepine withdrawal syndrome, which can cause a range of symptoms including insomnia, anxiety, and seizures. Other drugs, such as barbiturates, work in a similar way but have different effects on the duration or frequency of chloride channel opening.
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This question is part of the following fields:
- Psychiatry
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Question 17
Correct
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A 24-year-old male has just begun taking risperidone for schizophrenia. Soon after starting the medication, he observes that his breasts have become enlarged and there is some discharge. He also confesses to experiencing a decrease in libido and erectile dysfunction.
What dopaminergic pathway is being suppressed to result in this manifestation, which is diagnosed as hyperprolactinemia due to the use of antipsychotics?Your Answer: Tuberoinfundibular pathway
Explanation:Antipsychotics cause hyperprolactinaemia by inhibiting the tuberoinfundibular pathway, a dopaminergic pathway that originates from the hypothalamus and extends to the median eminence. This inhibition results in an increase in prolactin levels, which is responsible for the patient’s symptoms. Parkinson’s disease is associated with dysfunction in the nigrostriatal pathway, while schizophrenia is linked to abnormalities in the mesolimbic and mesocortical pathways. The corticospinal tract is involved in movement.
Antipsychotics are a type of medication used to treat schizophrenia, psychosis, mania, and agitation. They are divided into two categories: typical and atypical antipsychotics. The latter were developed to address the extrapyramidal side-effects associated with the first generation of typical antipsychotics. Typical antipsychotics work by blocking dopaminergic transmission in the mesolimbic pathways through dopamine D2 receptor antagonism. However, they are known to cause extrapyramidal side-effects such as Parkinsonism, acute dystonia, akathisia, and tardive dyskinesia. These side-effects can be managed with procyclidine. Other side-effects of typical antipsychotics include antimuscarinic effects, sedation, weight gain, raised prolactin, impaired glucose tolerance, neuroleptic malignant syndrome, reduced seizure threshold, and prolonged QT interval. The Medicines and Healthcare products Regulatory Agency has issued specific warnings when antipsychotics are used in elderly patients due to an increased risk of stroke and venous thromboembolism.
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This question is part of the following fields:
- Psychiatry
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Question 18
Correct
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A 52-year-old woman visited her family doctor with a complaint of long-standing abdominal discomfort. She describes the discomfort as diffuse and feels a heavy dragging sensation in her abdomen. Upon further inquiry, she reveals that she has been experiencing this abdominal discomfort for a few years. Her medical records indicate that she has undergone various investigations, including imaging studies and upper gastrointestinal endoscopy, but none of them revealed any significant findings. Recently, her CA-125 levels were found to be normal. The woman has a history of mild depression and takes citalopram. She also reports experiencing bodily pain in multiple locations. Physical examination does not reveal any abnormalities. What is the most likely diagnosis for this woman?
Your Answer: Somatic symptom disorder
Explanation:The patient’s symptoms were indicative of a psychiatric condition associated with somatic symptom disorders, rather than a manifestation of hypochondria or cancer.
Unexplained Symptoms in Psychiatry
In psychiatry, there are several terms used to describe patients who present with physical or psychological symptoms for which no organic cause can be found. Somatisation disorder is characterized by the presence of multiple physical symptoms that persist for at least two years, and the patient refuses to accept reassurance or negative test results. Illness anxiety disorder, also known as hypochondriasis, involves a persistent belief in the presence of an underlying serious disease, such as cancer, despite negative test results. Conversion disorder typically involves the loss of motor or sensory function, and the patient does not consciously feign the symptoms or seek material gain. Dissociative disorder involves the process of separating off certain memories from normal consciousness, and may present with psychiatric symptoms such as amnesia, fugue, or stupor. Factitious disorder, also known as Munchausen’s syndrome, involves the intentional production of physical or psychological symptoms, while malingering refers to the fraudulent simulation or exaggeration of symptoms for financial or other gain. These terms help clinicians to better understand and diagnose patients with unexplained symptoms.
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This question is part of the following fields:
- Psychiatry
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Question 19
Correct
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You come across a young woman who has recently been diagnosed with schizophrenia. She is curious about what her future may look like with the condition.
Your Answer: Associated with a poor prognosis
Explanation:A prodromal phase characterized by social withdrawal is linked to a negative prognosis in individuals with schizophrenia.
Schizophrenia is a mental disorder that can have varying outcomes for individuals. There are certain factors that have been associated with a poor prognosis, meaning a less favorable outcome. These factors include a strong family history of the disorder, a gradual onset of symptoms, a low IQ, a prodromal phase of social withdrawal, and a lack of an obvious precipitant for the onset of symptoms. It is important to note that these factors do not guarantee a poor outcome, but they may increase the likelihood of it. It is also important to seek treatment and support regardless of these factors, as early intervention and ongoing care can greatly improve outcomes for individuals with schizophrenia.
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This question is part of the following fields:
- Psychiatry
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Question 20
Correct
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A male patient with paranoid schizophrenia is admitted following a relapse in his psychotic symptoms. Upon admission, it is observed that he echoes the nurse's words.
What is the term for this phenomenon of echoing others' words?Your Answer: Echolalia
Explanation:Speech Disorders: Echolalia, Logorrhea, Paragrammatism, Paraphasia, and Verbigeration
Echolalia, logorrhea, paragrammatism, paraphasia, and verbigeration are all speech disorders that can be seen in various psychiatric and neurological conditions. Echolalia is the repetition of words or parts of speech spoken by others, while logorrhea is excessive wordiness with limited content or incomprehensible speech. Paragrammatism is the loss of grammatical coherence in speech, and paraphasia is characterised by the mispronunciation of single words or the combination of words in inappropriate or meaningless ways. Finally, verbigeration is the monotonous repetition of parts of speech.
These speech disorders can be seen in conditions such as schizophrenia, mania, and other organic disorders. these disorders can help healthcare professionals diagnose and treat patients more effectively. By identifying the specific speech disorder, appropriate interventions can be implemented to improve communication and overall quality of life for the patient.
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This question is part of the following fields:
- Psychiatry
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Question 21
Correct
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A 26-year-old woman confides in you that she cannot leave her house without first performing a specific ritual of sanitizing her door handle and washing her hands before and after leaving. She admits that if she deviates from this routine, she becomes extremely anxious and tense. This behavior has been ongoing for two years and is causing her significant distress.
What is the recommended course of treatment for this probable diagnosis?Your Answer: Exposure-response prevention (ERP) therapy
Explanation:Understanding Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a mental health condition that affects 1 to 2% of the population. It is characterized by the presence of obsessions, which are unwanted intrusive thoughts, images, or urges, and compulsions, which are repetitive behaviors or mental acts that a person feels driven to perform. OCD can cause significant functional impairment and distress.
The causes of OCD are multifactorial, with possible factors including genetics, psychological trauma, and pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). OCD is also associated with other mental health conditions such as depression, schizophrenia, Sydenham’s chorea, Tourette’s syndrome, and anorexia nervosa.
Treatment for OCD depends on the level of functional impairment. For mild impairment, low-intensity psychological treatments such as cognitive behavioral therapy (CBT) including exposure and response prevention (ERP) may be sufficient. If this is not effective or the patient cannot engage in psychological therapy, a course of an SSRI or more intensive CBT (including ERP) may be offered. For moderate impairment, a choice of either an SSRI or more intensive CBT (including ERP) may be offered. For severe impairment, combined treatment with an SSRI and CBT (including ERP) may be necessary.
ERP is a psychological method that involves exposing a patient to an anxiety-provoking situation and then stopping them from engaging in their usual safety behavior. This helps them confront their anxiety, and the habituation leads to the eventual extinction of the response. If treatment with an SSRI is effective, it should be continued for at least 12 months to prevent relapse and allow time for improvement. If an SSRI is ineffective or not tolerated, another SSRI may be tried.
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This question is part of the following fields:
- Psychiatry
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Question 22
Correct
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A 42-year-old unemployed male who resides in a hostel is admitted to the medical ward after experiencing upper gastrointestinal bleeding. He has a history of alcohol detoxes and is known to the Alcohol and Drugs Services.
On the third day of his hospitalization, he becomes agitated and begins shouting about insects crawling on the walls in his room.
What is the probable reason for his current presentation?Your Answer: Delirium tremens
Explanation:Visual Hallucinations in Organic Psychosis
Visual hallucinations are a common occurrence in organic psychosis, particularly in cases of delirium. These hallucinations often take the form of animals and people. In cases of alcoholic delirium, the visual hallucinations tend to be small objects such as spider webs or hairs, which appear against a clear background like a white wall.
It is important to note that the psychotic experiences associated with delirium tremens can be mistaken for other psychotic illnesses like schizophrenia or mania. However, delirium is a medical emergency that requires immediate medical attention. Admission to a psychiatric hospital may not be the best course of action due to a lack of trained staff in emergency medicine.
In summary, visual hallucinations are a common symptom of organic psychosis, particularly in cases of delirium. These hallucinations can take many forms, including animals, people, and small objects. It is important to seek medical attention immediately if experiencing these symptoms, as delirium is a medical emergency that requires prompt treatment.
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This question is part of the following fields:
- Psychiatry
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Question 23
Incorrect
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What kind of hallucination is it when Lilly hears the phone ringing and John Lennon's voice at the same time?
Your Answer: Auditory illusion
Correct Answer: Functional hallucination
Explanation:Types of Hallucinations and Illusions
Functional hallucinations are auditory hallucinations that occur in response to an external stimulus. The individual can distinguish between the stimulus and the hallucination, and the hallucination only occurs when the stimulus is present. Reflex hallucinations, on the other hand, occur when a sensory stimulus in one modality causes a hallucination in another modality.
Autoscopy, also known as phantom mirror-image, is the experience of seeing oneself and recognizing that it is oneself. This can be a disorienting experience, as the individual may feel as though they are outside of their own body. Extracampine hallucinations occur when an individual experiences a hallucination outside of their own sensory field, such as seeing something behind them when they are looking straight ahead.
Auditory illusions occur when an auditory stimulus is misinterpreted by the listener. This can happen when the listener is in a noisy environment or when the sound is distorted in some way. It is important to note that hallucinations and illusions can be symptoms of various mental health conditions and should be evaluated by a medical professional.
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This question is part of the following fields:
- Psychiatry
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Question 24
Correct
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A young adult visits the doctor with a complaint of a minor burn on their hand. During the consultation, they go into great detail about the events leading up to the burn, including what they were cooking and their favorite recipes. It takes a while before they finally mention the burn. Given their history of anxiety, what would be the classification of this behavior?
Your Answer: Circumstantiality
Explanation:Anxiety is a common disorder that can manifest in various ways. According to NICE, the primary feature is excessive worry about multiple events associated with heightened tension. It is crucial to consider potential physical causes when diagnosing psychiatric disorders such as anxiety. Hyperthyroidism, cardiac disease, and medication-induced anxiety are important alternative causes. Medications that may trigger anxiety include salbutamol, theophylline, corticosteroids, antidepressants, and caffeine.
NICE recommends a step-wise approach for managing generalised anxiety disorder (GAD). The first step is education about GAD and active monitoring. The second step involves low-intensity psychological interventions such as individual non-facilitated self-help, individual guided self-help, or psychoeducational groups. The third step includes high-intensity psychological interventions such as cognitive behavioural therapy or applied relaxation, or drug treatment. Sertraline is the first-line SSRI recommended by NICE. If sertraline is ineffective, an alternative SSRI or a serotonin–noradrenaline reuptake inhibitor (SNRI) such as duloxetine or venlafaxine may be offered. If the person cannot tolerate SSRIs or SNRIs, pregabalin may be considered. For patients under the age of 30 years, NICE recommends warning them of the increased risk of suicidal thinking and self-harm and weekly follow-up for the first month.
The management of panic disorder also follows a stepwise approach. The first step is recognition and diagnosis, followed by treatment in primary care. NICE recommends either cognitive behavioural therapy or drug treatment. SSRIs are the first-line treatment. If contraindicated or no response after 12 weeks, imipramine or clomipramine should be offered. The third step involves reviewing and considering alternative treatments, followed by review and referral to specialist mental health services in the fourth and fifth steps, respectively.
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This question is part of the following fields:
- Psychiatry
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Question 25
Correct
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A 28-year-old man with schizophrenia who began taking clozapine 2 weeks ago visits for his routine blood test. What is a known severe side effect of clozapine?
Your Answer: Agranulocytosis
Explanation:Clozapine, an antipsychotic medication used to treat refractory schizophrenia, requires continuous monitoring for patients taking it. This involves weekly blood tests for the first 18 weeks, followed by bi-weekly tests until the first year, and then monthly tests thereafter.
Atypical antipsychotics are now recommended as the first-line treatment for patients with schizophrenia, as per the 2005 NICE guidelines. These agents have a significant advantage over traditional antipsychotics in that they cause fewer extrapyramidal side-effects. However, atypical antipsychotics can still cause adverse effects such as weight gain, hyperprolactinaemia, and clozapine-associated agranulocytosis. Elderly patients who take antipsychotics are at an increased risk of stroke and venous thromboembolism, according to the Medicines and Healthcare products Regulatory Agency.
Clozapine is one of the first atypical antipsychotics to be developed, but it carries a significant risk of agranulocytosis. Therefore, full blood count monitoring is essential during treatment. Clozapine should only be used in patients who are resistant to other antipsychotic medication. The BNF recommends introducing clozapine if schizophrenia is not controlled despite the sequential use of two or more antipsychotic drugs, one of which should be a second-generation antipsychotic drug, each for at least 6-8 weeks. Clozapine can cause adverse effects such as reduced seizure threshold, constipation, myocarditis, and hypersalivation. Dose adjustment of clozapine may be necessary if smoking is started or stopped during treatment.
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This question is part of the following fields:
- Psychiatry
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Question 26
Correct
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After the passing of a dear friend, a 22-year-old male comes in with symptoms of confusion and auditory hallucinations. He appears to be in great distress and has developed a belief that he is a malevolent sorcerer. It is suspected that he may be experiencing brief psychotic disorder.
What are some characteristics of this disorder?Your Answer: It often results in a return to baseline functioning
Explanation:Brief psychotic disorder is a condition characterized by a sudden onset of psychotic symptoms, such as hallucinations or delusions, that typically occurs in response to a stressful event. Individuals with a pre-existing personality disorder may be more susceptible to this condition. However, the good news is that brief psychotic disorder often resolves within a month, and patients typically return to their normal level of functioning. This disorder is most commonly seen in individuals in their 20s, 30s, and 40s, and patients may not always be aware of the changes in their behavior.
Understanding Psychosis: Symptoms and Associated Features
Psychosis is a term used to describe a person’s experience of perceiving things differently from those around them. This can manifest in a variety of ways, including hallucinations, delusions, thought disorganization, alogia, tangentiality, clanging, and word salad. These symptoms can be associated with agitation, aggression, neurocognitive impairment, depression, and thoughts of self-harm.
Psychotic symptoms can occur in a number of conditions, including schizophrenia, depression, bipolar disorder, puerperal psychosis, brief psychotic disorder, neurological conditions like Parkinson’s disease and Huntington’s disease, and as a result of prescribed drugs or certain illicit drugs like cannabis and phencyclidine.
The peak age of first-episode psychosis is around 15-30 years. It is important to understand the symptoms and associated features of psychosis in order to recognize and seek appropriate treatment for those experiencing these symptoms.
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This question is part of the following fields:
- Psychiatry
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Question 27
Correct
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A 42-year-old patient with schizophrenia has been repeatedly calling the police, claiming that her neighbors are attempting to kill her by filling her apartment with gas. She insists that she can smell gas in her apartment at all times, despite having an electric stove. What kind of abnormal perception is this likely to be?
Your Answer: Olfactory hallucination
Explanation:Types of Hallucinations
Hallucinations are sensory experiences that are not based on reality. They can occur in various forms, including olfactory, gustatory, kinaesthetic, hypnagogic, and tactile. Olfactory hallucinations involve smelling something that is not present, and can be associated with organic disorders such as temporal lobe epilepsy or psychotic disorders like schizophrenia. It is important to rule out other organic disorders before diagnosing a psychotic disorder.
Gustatory hallucinations involve experiencing a taste that is not present, while kinaesthetic hallucinations involve feeling a sensation of movement. Hypnagogic hallucinations occur when a person hears a voice upon awakening, which can be a normal experience. Tactile hallucinations involve feeling a sensation of touch that is not present.
the different types of hallucinations is important for proper diagnosis and treatment. It is essential to rule out any underlying organic disorders before attributing the hallucinations to a psychotic disorder.
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This question is part of the following fields:
- Psychiatry
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Question 28
Incorrect
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A 50-year-old alcoholic has been brought to the emergency department by his sister. His sister reports that he has been disoriented for the past few days and has had a few falls. Upon examination, he displays an unstable gait. He is unable to recall the name of the first female prime minister of the UK or the trip to the emergency department. He insists that he went to the beach yesterday - which his sister denies. Based on the presented symptoms, what is the probable diagnosis?
Your Answer: Wernicke's encephalopathy
Correct Answer: Korsakoff's syndrome
Explanation:The symptoms of Korsakoff’s syndrome, which is a complication of Wernicke’s encephalopathy, include anterograde amnesia, retrograde amnesia, and confabulation. This patient initially presented with confusion and an unsteady gait, which are signs of ataxia associated with Wernicke’s encephalopathy. However, the presence of anterograde amnesia, retrograde amnesia, and confabulation suggests that the patient’s condition has progressed to Korsakoff’s syndrome.
In contrast, Alzheimer’s disease typically affects memory in a gradual and progressive manner.
Understanding Korsakoff’s Syndrome
Korsakoff’s syndrome is a memory disorder that is commonly observed in individuals who have a history of alcoholism. This condition is caused by a deficiency in thiamine, which leads to damage and haemorrhage in the mammillary bodies of the hypothalamus and the medial thalamus. Korsakoff’s syndrome often follows untreated Wernicke’s encephalopathy, which is another condition caused by thiamine deficiency.
The primary features of Korsakoff’s syndrome include anterograde amnesia, which is the inability to acquire new memories, and retrograde amnesia. Individuals with this condition may also experience confabulation, which is the production of fabricated or distorted memories to fill gaps in their recollection.
Understanding Korsakoff’s syndrome is crucial for individuals who have a history of alcoholism or thiamine deficiency. Early diagnosis and treatment can help prevent further damage and improve the individual’s quality of life. Proper nutrition and abstinence from alcohol are essential for managing this condition.
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This question is part of the following fields:
- Psychiatry
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Question 29
Incorrect
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A 32-year-old man is in a serious car crash that results in the death of his wife and son. Upon arrival at the Emergency Department, he appears composed and shows no signs of physical or emotional distress. However, he cannot recall the details of the accident and believes his family is unharmed. If there is no evidence of organic brain damage, which ego defense mechanism is he exhibiting?
Your Answer: Repression
Correct Answer: Dissociation
Explanation:Dissociation is a coping mechanism that involves a temporary and drastic change in personality, memory, consciousness, or motor behavior in response to emotional stress. It often results in incomplete or no memory of the traumatic event. In severe cases, it can lead to dissociative identity disorder, also known as multiple personality disorder. Other examples of coping mechanisms include denial, which involves avoiding awareness of a painful reality, repression, which involves involuntarily withholding an idea or feeling from conscious awareness, and sublimation, which involves redirecting an unacceptable wish towards a course of action that aligns with one’s values, such as channeling aggression into sports performance.
Understanding Ego Defenses
Ego defenses are psychological mechanisms that individuals use to protect themselves from unpleasant emotions or thoughts. These defenses are classified into four levels, each with its own set of defense mechanisms. The first level, psychotic defenses, is considered pathological as it distorts reality to avoid dealing with it. The second level, immature defenses, includes projection, acting out, and projective identification. The third level, neurotic defenses, has short-term benefits but can lead to problems in the long run. These defenses include repression, rationalization, and regression. The fourth and most advanced level, mature defenses, includes altruism, sublimation, and humor.
Despite the usefulness of understanding ego defenses, their classification and definitions can be inconsistent and frustrating to learn for exams. It is important to note that these defenses are not necessarily good or bad, but rather a natural part of human behavior. By recognizing and understanding our own ego defenses, we can better manage our emotions and thoughts in a healthy way.
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This question is part of the following fields:
- Psychiatry
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Question 30
Correct
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Tina, who is in her mid-30s, is currently facing a challenging situation at work that is causing her to feel increasingly frustrated and angry. To cope with these emotions, she has decided to take up kickboxing as a form of release. By channeling her energy into physical activity, Tinais able to manage her anger in a healthy way. This is an example of which defense mechanism?
Your Answer: Sublimation
Explanation:Defense Mechanisms: Coping Strategies for Unacceptable Emotions
Defense mechanisms are psychological strategies that individuals use to cope with unacceptable emotions and thoughts. These mechanisms are often unconscious and can be helpful in managing difficult situations. One such mechanism is sublimation, which involves channeling negative emotions into more acceptable outlets. For example, a person who is angry may choose to engage in physical exercise as a way to release their emotions.
Another defense mechanism is displacement, which involves transferring emotions from one person or situation to another. This can be seen when a person who is angry with their boss comes home and takes out their frustration on their family members. Intellectualization is another mechanism that allows individuals to focus on the facts of a situation rather than the emotions they are feeling. This can be helpful in situations where emotions may be overwhelming, such as when dealing with a serious illness.
Rationalization is a defense mechanism that allows individuals to justify their behavior in a logical manner when their ego is threatened. For example, a student who fails an exam may blame the teacher rather than accepting responsibility for their own actions. Finally, denial is a mechanism that involves consciously avoiding painful topics. This can be seen when a patient denies being told that they have a serious illness.
Overall, defense mechanisms can be helpful in managing difficult emotions and situations. However, it is important to recognize when these mechanisms are being used and to seek help if they are interfering with daily life.
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This question is part of the following fields:
- Psychiatry
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