-
Question 1
Correct
-
During a routine check-up, a 7 week-old baby boy is seen. His mother has a history of asthma and used inhaled steroids while pregnant. He was delivered via planned Caesarian at 39 weeks due to breech presentation and weighed 3.1kg at birth. What condition is he at a higher risk for?
Your Answer: Developmental dysplasia of the hip
Explanation:If a baby was in a breech presentation, it is important to ensure that they have been referred for screening for developmental dysplasia of the hip (DDH) as it is a risk factor for this condition. The Department of Health recommends that all babies who were breech at any point from 36 weeks (even if not breech at birth), babies born before 36 weeks who were in a breech presentation, and all babies with a first degree relative who had a hip problem in early life, should undergo ultrasound screening for hip dysplasia. If one twin was breech, both should be screened. Some hospitals also refer babies with other conditions such as oligohydramnios, high birth weight, torticollis, congenital talipes calcaneovalgus, and metatarsus adductus for screening. For more information on screening for DDH, please refer to the link provided.
Developmental dysplasia of the hip (DDH) is a condition that affects 1-3% of newborns and is more common in females, firstborn children, and those with a positive family history or breech presentation. It used to be called congenital dislocation of the hip (CDH). DDH is more often found in the left hip and can be bilateral in 20% of cases. Screening for DDH is recommended for infants with certain risk factors, and all infants are screened using the Barlow and Ortolani tests at the newborn and six-week baby check. Clinical examination includes testing for leg length symmetry, restricted hip abduction, and knee level when hips and knees are flexed. Ultrasound is used to confirm the diagnosis if clinically suspected, but x-ray is the first line investigation for infants over 4.5 months. Management includes the use of a Pavlik harness for children under 4-5 months and surgery for older children with unstable hips.
-
This question is part of the following fields:
- Paediatrics
-
-
Question 2
Correct
-
A 32-year-old teacher presents with bloody diarrhoea; he says that he has been passing up to 10 motions a day for the past 3–4 weeks. He now presents to the Emergency Department, complaining of abdominal pain and bloating. On examination, he is dehydrated with a clearly distended, tender abdomen. There is anaemia with raised plasma viscosity; potassium level is mildly decreased at 3.3 mmol/l (reference range 3.5–5.1 mmol/l), and urea level is raised, in keeping with dehydration. Liver function testing reveals a decreased albumin level. Autoantibody screen is positive for c-ANCA (cytoplasmic anti-neutrophil cytoplasmic antibody). Colonoscopy shows friable mucosa with a uniform pattern of inflammation and loss of normal mucosa. Stool culture is negative.
Which one of these diagnoses fits best with this clinical picture?Your Answer: Ulcerative colitis
Explanation:Ulcerative colitis is a type of inflammatory bowel disease that affects only the large bowel. Symptoms include rectal bleeding, frequent stools, and mucus discharge from the rectum. Diagnosis is confirmed through sigmoidoscopy, which reveals continuous inflammation with loss of normal mucosa and intense infiltration of the mucosa and submucosa with various immune cells. The presence of p-ANCA is highly associated with UC. Crohn’s disease, coeliac disease, ischaemic colitis, and diverticulitis have different clinical presentations and diagnostic criteria, which do not match the symptoms and test results of this patient.
-
This question is part of the following fields:
- Gastroenterology/Nutrition
-
-
Question 3
Incorrect
-
A 25-year-old man with a history of bipolar disorder is scheduled for a medication review. When inquiring about his current state, he starts discussing the vast array of emotions that exist and wonders if everyone has experienced all of them. Eventually, he spontaneously mentions that he is feeling quite good.
What is the patient exhibiting in this scenario?Your Answer: Derailment
Correct Answer: Circumstantiality
Explanation:The patient’s lengthy response to the question suggests circumstantiality, which can be a symptom of anxiety disorders or hypomania. However, the patient has remained on topic and has not derailed. Their response is coherent, and there is no evidence of pressured speech in this text-based interaction. Incoherence would be demonstrated by nonsensical statements, which is not the case here.
Anxiety is a common disorder that can manifest in various ways. According to NICE, the primary feature is excessive worry about multiple events associated with heightened tension. It is crucial to consider potential physical causes when diagnosing anxiety disorders, such as hyperthyroidism, cardiac disease, and medication-induced anxiety. Medications that may trigger anxiety include salbutamol, theophylline, corticosteroids, antidepressants, and caffeine.
NICE recommends a step-wise approach for managing generalised anxiety disorder (GAD). This includes education about GAD and active monitoring, low-intensity psychological interventions, high-intensity psychological interventions or drug treatment, and highly specialist input. Sertraline is the first-line SSRI for drug treatment, and if it is ineffective, an alternative SSRI or a serotonin-noradrenaline reuptake inhibitor (SNRI) such as duloxetine or venlafaxine may be offered. If the patient cannot tolerate SSRIs or SNRIs, pregabalin may be considered. For patients under 30 years old, NICE recommends warning them of the increased risk of suicidal thinking and self-harm and weekly follow-up for the first month.
The management of panic disorder also follows a stepwise approach, including recognition and diagnosis, treatment in primary care, review and consideration of alternative treatments, review and referral to specialist mental health services, and care in specialist mental health services. NICE recommends either cognitive behavioural therapy or drug treatment in primary care. SSRIs are the first-line drug treatment, and if contraindicated or no response after 12 weeks, imipramine or clomipramine should be offered.
-
This question is part of the following fields:
- Psychiatry
-
-
Question 4
Incorrect
-
A 20-year-old male patient comes to the GP clinic with a history of lower back pain and stiffness that has been gradually worsening for the past 6 months. He reports that the stiffness is more pronounced in the morning but improves throughout the day and with physical activity. He mentions that his mother has a form of arthritis but cannot remember which type. He denies experiencing any night sweats or weight loss.
What is a red flag symptom of lower back pain?Your Answer: Morning stiffness
Correct Answer:
Explanation:One of the warning signs of lower back pain is when it starts before the age of 20 or after the age of 50. Morning stiffness may indicate an inflammatory cause for the pain, but it is not a definitive symptom. The presence of arthritis in the family may be significant, particularly if it is ankylosing spondylitis, which can be inherited through the HLA-B27 gene. However, the specific type of arthritis in the family was not specified. Being male is not considered a warning sign.
Lower back pain is a common issue that is often caused by muscular strain. However, it is important to be aware of potential underlying causes that may require specific treatment. Certain red flags should be considered, such as age under 20 or over 50, a history of cancer, night pain, trauma, or systemic illness. There are also specific causes of lower back pain that should be kept in mind. Facet joint pain may be acute or chronic, worse in the morning and on standing, and typically worsens with back extension. Spinal stenosis may cause leg pain, numbness, and weakness that is worse on walking and relieved by sitting or leaning forward. Ankylosing spondylitis is more common in young men and causes stiffness that is worse in the morning and improves with activity. Peripheral arterial disease may cause pain on walking and weak foot pulses. It is important to consider these potential causes and seek appropriate diagnosis and treatment.
-
This question is part of the following fields:
- Musculoskeletal
-
-
Question 5
Correct
-
A 56-year-old man visits his GP with complaints of bilateral gritty and sore eyes that have persisted for several weeks. He denies any history of trauma and has not experienced any discharge. He has not noticed any blurred vision. The patient's medical history is significant only for back pain, which he is managing with paracetamol and amitriptyline. During the examination, his visual acuity is 6/6 corrected bilaterally, and there are no apparent corneal or pupillary abnormalities. His eyes are not red, and eye movements are normal. What is the most probable diagnosis?
Your Answer: Dry eye syndrome
Explanation:Dry eye syndrome is a common cause of bilateral sore eyes with a gritty or burning sensation. This can be treated with topical lubrication, such as hypromellose. While an examination may appear normal, fluorescein staining can reveal superficial punctate staining and Schirmer’s test may indicate reduced tear production. It is important to consider allergic conjunctivitis as a possible differential diagnosis, especially if symptoms persist for a prolonged period of time and there are no signs of conjunctival involvement.
Understanding Dry Eye Syndrome
Dry eye syndrome is a condition that causes discomfort in both eyes, with symptoms such as dryness, grittiness, and soreness that worsen throughout the day. Exposure to wind can also cause watering of the eyes. People with Meibomian gland dysfunction may experience symptoms that are worse upon waking, with eyelids sticking together and redness of the eyelids. In some cases, dry eye syndrome can lead to complications such as conjunctivitis or corneal ulceration, which can cause severe pain, photophobia, redness, and loss of visual acuity.
Although there may be no abnormalities on examination, eyelid hygiene is the most appropriate management step for dry eye syndrome. This can help control blepharitis, which is a common condition associated with dry eye syndrome. By understanding the symptoms and appropriate management steps, individuals with dry eye syndrome can find relief and improve their overall eye health.
-
This question is part of the following fields:
- Ophthalmology
-
-
Question 6
Incorrect
-
A 67-year-old man presents for a review of his chronic obstructive pulmonary disease. He reports experiencing constant shortness of breath during physical activity, which has remained stable over the past year. He has a history of asbestos exposure and is currently under the care of a respiratory physician. During the examination, no abnormalities are detected, but a chest X-ray reveals the presence of pleural plaques. The patient expresses concern that these plaques may develop into cancer. What advice do you offer this patient regarding his test results?
Your Answer: Malignant and require immediate specialist referral
Correct Answer: Benign and do not require follow-up
Explanation:Pleural plaques are benign and do not develop into cancerous growths, so there is no need for any follow-up. These plaques are the most common form of lung disease caused by asbestos exposure, but they do not increase the risk of lung cancer or mesothelioma. While ongoing monitoring of the patient’s lung disease is recommended, there is no need to specifically monitor the pleural plaques. It is important to note that pleural plaques are a sign of past asbestos exposure, which could increase the risk of mesothelioma, but the plaques themselves are not a cause for concern. Therefore, the patient does not require a specialist referral for the pleural plaques alone. However, if the patient experiences worsening shortness of breath or frequent exacerbations, a specialist referral may be necessary to assess for disease progression or malignancy.
Asbestos-Related Lung Diseases
Asbestos exposure can lead to various lung diseases, ranging from benign pleural plaques to malignant mesothelioma. Pleural plaques are non-cancerous and do not require any follow-up, but they are the most common form of asbestos-related lung disease and typically appear after a latent period of 20-40 years. Asbestos exposure may also cause diffuse pleural thickening, which is similar to the pattern seen after an empyema or haemothorax, but the underlying pathophysiology is not fully understood.
Asbestosis is a lung disease that is related to the length of exposure to asbestos. It causes lower lobe fibrosis and is typically characterized by dyspnea, reduced exercise tolerance, clubbing, bilateral end-inspiratory crackles, and a restrictive pattern with reduced gas transfer on lung function tests. Asbestosis is treated conservatively, as no interventions offer significant benefits. The latent period for asbestosis is typically 15-30 years.
Mesothelioma is a malignant disease of the pleura that is caused by asbestos exposure, with crocidolite (blue) asbestos being the most dangerous form. Possible features of mesothelioma include progressive shortness-of-breath, chest pain, and pleural effusion. Patients are usually offered palliative chemotherapy, and there is a limited role for surgery and radiotherapy. Unfortunately, the prognosis for mesothelioma is very poor, with a median survival from diagnosis of 8-14 months.
Although mesothelioma is often associated with asbestos exposure, lung cancer is actually the most common form of cancer related to asbestos exposure. It has a synergistic effect with cigarette smoke, which increases the risk of developing lung cancer.
-
This question is part of the following fields:
- Respiratory Medicine
-
-
Question 7
Correct
-
Among the drugs listed, which one is the most probable cause of diarrhoea as a side effect? Please select only one option.
Your Answer: Lansoprazole
Explanation:Gastrointestinal Side Effects of Common Medications
Lansoprazole, a proton pump inhibitor, is known to cause gastrointestinal disturbances such as abdominal pain, constipation, flatulence, nausea, vomiting, and diarrhea. This is because it reduces the acidity of the stomach, allowing bacterial flora to proliferate.
Amitriptyline, a tricyclic antidepressant, can cause abdominal pain, anorexia, constipation, increased appetite, nausea, and weight gain or loss. However, it is not associated with diarrhea.
Calcium carbonate, a calcium supplement, can commonly cause gastrointestinal disturbances but is not known to cause diarrhea.
Carbamazepine, an anticonvulsant, commonly causes nausea and vomiting, and rarely constipation and diarrhea. The rarity of diarrhea as a side effect suggests that an alternative option may be more appropriate.
Codeine phosphate, an opioid analgesic, can cause constipation, nausea, and vomiting, but is not known to cause diarrhea.
-
This question is part of the following fields:
- Pharmacology/Therapeutics
-
-
Question 8
Incorrect
-
A 22-month-old toddler presents to the GP with a barking cough and fever for 3 days. The fever has been responding to regular paracetamol. The child's parent reports that the toddler is eating and drinking normally and has been urinating regularly. During playtime, the parent has noticed some increased breathing sounds, but they disappear when the child is at rest. There have been no febrile convulsions, rash, or drowsiness reported.
Upon examination, the toddler has a clear chest with no signs of increased work of breathing. An occasional barking cough is heard.
What is the most appropriate management for this toddler?Your Answer: Delayed antibiotic prescription
Correct Answer: Oral dexamethasone
Explanation:For this infant with mild croup, the recommended treatment is a single dose of oral dexamethasone (0.15 mg/kg body weight) regardless of the severity of symptoms. This should be taken immediately to reduce upper airway inflammation and alleviate the occasional barking cough and stridor. Delayed antibiotic prescription, immediate oral antibiotics, humidified oxygen, and inhaled or nebulised salbutamol are not appropriate options for croup management. Antibiotics are ineffective against viruses, which are the most common cause of croup, while humidified oxygen and inhaled or nebulised salbutamol are used for other respiratory conditions.
Understanding Croup: A Respiratory Infection in Infants and Toddlers
Croup is a type of upper respiratory tract infection that commonly affects infants and toddlers. It is characterized by a barking cough, fever, and coryzal symptoms, and is caused by a combination of laryngeal oedema and secretions. Parainfluenza viruses are the most common cause of croup. The condition typically peaks between 6 months and 3 years of age, and is more prevalent during the autumn season.
The severity of croup can be graded based on the presence of symptoms such as stridor, cough, and respiratory distress. Mild cases may only have occasional barking cough and no audible stridor at rest, while severe cases may have frequent barking cough, prominent inspiratory stridor at rest, and marked sternal wall retractions. Children with moderate or severe croup, those under 6 months of age, or those with known upper airway abnormalities should be admitted to the hospital.
Diagnosis of croup is usually made based on clinical presentation, but a chest x-ray may show subglottic narrowing, commonly referred to as the steeple sign. Treatment for croup typically involves a single dose of oral dexamethasone or prednisolone, regardless of severity. In emergency situations, high-flow oxygen and nebulized adrenaline may be necessary.
Understanding croup is important for parents and healthcare providers alike, as prompt recognition and treatment can help prevent complications and improve outcomes for affected children.
-
This question is part of the following fields:
- Paediatrics
-
-
Question 9
Correct
-
A 70-year-old man is brought to the Emergency Department by his wife who reports that he has been feeling down lately. She also mentions that he ingested 30 atenolol 50mg tablets about four hours ago. Upon assessment, his pulse is recorded at 42 beats per minute and his blood pressure is 98/62 mmHg. What is the initial treatment option that should be considered?
Your Answer: Intravenous atropine
Explanation:If gastric lavage is to be attempted, it should only be done within 1-2 hours of the patient taking the overdose.
Managing Beta-Blocker Overdose
Beta-blocker overdose can lead to various symptoms such as bradycardia, hypotension, heart failure, and syncope. To manage these symptoms, it is important to first identify if the patient is bradycardic. If so, atropine can be administered. However, in cases where atropine is not effective, glucagon may be used as an alternative. It is important to note that haemodialysis is not an effective treatment for beta-blocker overdose. Proper management of beta-blocker overdose is crucial in preventing further complications and ensuring the patient’s safety.
-
This question is part of the following fields:
- Pharmacology/Therapeutics
-
-
Question 10
Correct
-
You are having a consultation with a 49-year-old man for his initial diabetes review. Following 3 months of metformin treatment, his HbA1c has shown improvement. Unfortunately, he hasn't been able to make any lifestyle modifications. You are content with the management of his type 2 diabetes mellitus. However, the patient reports experiencing significant gastrointestinal (GI) adverse effects due to metformin.
What would be your approach to managing this patient?Your Answer: Switch to a modified-release formulation of metformin
Explanation:If the patient experiences GI side-effects with metformin, it is recommended to try a modified-release formulation before considering switching to a second-line agent. Modified-release formulations are known to cause fewer GI side-effects compared to other formulations. It is advisable to continue with metformin as it is effective for the patient rather than trying another medication that may not work as well.
Continuing with the same formulation of metformin is not a suitable solution as the patient is experiencing significant GI side-effects. Modified-release formulations can help manage diabetes while reducing these side-effects.
Discontinuing all antidiabetic medications is not recommended as the patient has not made any lifestyle changes and requires medical support to manage their diabetes.
While second-line agents like sulfonylureas may be effective in managing diabetes and reducing GI side-effects, they may not be as effective as metformin and may cause their own set of side-effects. These medications should be considered only when combination therapy is required.
GLP-1 receptor antagonists are effective antidiabetic medications, but they are expensive and inconvenient as they require injection. Therefore, other medications should be tried before considering these.
Metformin is a medication commonly used to treat type 2 diabetes mellitus. It belongs to a class of drugs called biguanides and works by activating the AMP-activated protein kinase (AMPK), which increases insulin sensitivity and reduces hepatic gluconeogenesis. Additionally, it may decrease the absorption of carbohydrates in the gastrointestinal tract. Unlike other diabetes medications, such as sulphonylureas, metformin does not cause hypoglycemia or weight gain, making it a first-line treatment option, especially for overweight patients. It is also used to treat polycystic ovarian syndrome and non-alcoholic fatty liver disease.
While metformin is generally well-tolerated, gastrointestinal side effects such as nausea, anorexia, and diarrhea are common and can be intolerable for some patients. Reduced absorption of vitamin B12 is also a potential side effect, although it rarely causes clinical problems. In rare cases, metformin can cause lactic acidosis, particularly in patients with severe liver disease or renal failure. However, it is important to note that lactic acidosis is now recognized as a rare side effect of metformin.
There are several contraindications to using metformin, including chronic kidney disease, recent myocardial infarction, sepsis, acute kidney injury, severe dehydration, and alcohol abuse. Additionally, metformin should be discontinued before and after procedures involving iodine-containing x-ray contrast media to reduce the risk of contrast nephropathy.
When starting metformin, it is important to titrate the dose slowly to reduce the incidence of gastrointestinal side effects. If patients experience intolerable side effects, modified-release metformin may be considered as an alternative.
-
This question is part of the following fields:
- Pharmacology/Therapeutics
-
-
Question 11
Correct
-
A 32-year-old man visits the general surgery practice with a 2-year history of occasional abdominal discomfort, bloating and change in bowel habit, which alternates between loose stools and constipation. He reports that these episodes are most intense during his work-related stress and after consuming spicy food. There is no history of weight loss or presence of blood or mucus in the stool. Physical examination, including digital rectal examination, is unremarkable. Bloods, including full blood count, liver function test, thyroid function test and coeliac screen are all normal.
Which of the following is the most likely diagnosis?Your Answer: Irritable bowel syndrome (IBS)
Explanation:Differential Diagnosis for Abdominal Symptoms: Irritable Bowel Syndrome, Ulcerative Colitis, Colorectal Cancer, Polycystic Ovarian Syndrome, and Ovarian Cancer
Abdominal symptoms can be caused by a variety of conditions, making differential diagnosis crucial. Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. It is more prevalent in women and can be associated with stress. Diagnosis is made by excluding other differential diagnoses, and management includes psychological support and dietary measures, with pharmacological treatment as adjunctive therapy.
Ulcerative colitis (UC) presents with rectal bleeding, frequent stools, and mucus discharge from the rectum. Physical examination may reveal proctitis and left-sided abdominal tenderness. UC is associated with extracolonic manifestations, but this patient’s symptoms are not consistent with a diagnosis of UC.
Colorectal cancer typically presents with rectal bleeding, change in bowel habits, abdominal pain, weight loss, and malaise. However, this patient’s age, clinical history, and normal examination findings make this diagnosis unlikely.
Polycystic ovarian syndrome (PCOS) presents with hyperandrogenism symptoms such as oligomenorrhea, hirsutism, and acne. Abdominal pain, bloating, and change in bowel habits are not features of PCOS.
Ovarian cancer may present with minimal or non-specific symptoms, but persistent abdominal distension and/or pain, early satiety, or lethargy may be present. However, this patient’s young age makes this diagnosis less likely.
The National Institute for Health and Care Excellence recommends that any woman aged over 50 years who presents with new IBS-like symptoms within the past year should have ovarian cancer excluded with a serum CA125 measurement.
-
This question is part of the following fields:
- Gastroenterology/Nutrition
-
-
Question 12
Incorrect
-
A 45-year-old man visits his doctor complaining of difficulty lifting heavy objects and describes a feeling of weakness when climbing stairs. He has noticed occasional muscle twitches and spasms that seem to be increasing in frequency.
Which of the following is the most likely diagnosis?
Your Answer: Multiple sclerosis
Correct Answer: Polymyositis
Explanation:Based on the patient’s symptoms, the most likely diagnosis is polymyositis. This is a connective tissue disease that affects the striated muscles, causing symmetrical weakness in the proximal muscles. Patients may have difficulty rising from chairs and experience muscle tenderness. Creatine kinase levels are elevated, and a muscle biopsy can confirm the diagnosis. This presentation is not suggestive of Guillain-Barré syndrome, which typically presents with distal weakness that progresses proximally. Mononeuritis multiplex, which involves neuropathy of multiple peripheral and/or cranial nerves, is unlikely given the symmetrical distribution of symptoms affecting proximal muscles. Multiple sclerosis is also unlikely, as it tends to present with distal rather than proximal limb weakness or paraesthesia. Myasthenia gravis, which is associated with antibodies to acetylcholine receptors and causes fatigability, is not suggested by the patient’s symptoms.
-
This question is part of the following fields:
- Neurology
-
-
Question 13
Incorrect
-
A 35-year-old woman, who has been struggling with drug addiction and living on the streets, presents to the Emergency Department complaining of epigastric pain. The patient reports that she developed acute abdominal pain two hours prior to the presentation after eating a hot dog. The patient otherwise has no significant past medical history, takes no medications and admits to smoking and occasional alcohol consumption.
On examination, the patient has normal vital signs. Her abdominal examination demonstrates normoactive bowel sounds, no tenderness to palpation in the epigastrium and no guarding or rebound tenderness. Rectal exam for stool occult blood is negative and a chest X-ray does not reveal free air under the diaphragm. A right upper quadrant ultrasound does not demonstrate stones. The doctor recommends antacids. When the doctor tells the patient that she is safe for discharge, the patient insists that she must be admitted to the hospital for further tests.
Which of the following is the most likely diagnosis?Your Answer: Factitious disorder
Correct Answer: Malingering
Explanation:Differentiating between Malingering, Hypochondriasis, Conversion Disorder, Factitious Disorder, and Munchausen Syndrome by Proxy
When evaluating patients, it is important to differentiate between various conditions that may present with similar symptoms. Malingering is a condition where a patient feigns or exaggerates symptoms for secondary gain, such as meals or a place to sleep. Hypochondriasis, on the other hand, is a condition where a patient fears having a medical illness despite negative tests and reassurance. Conversion disorder refers to the manifestation of psychological illness as neurologic pathology, while factitious disorder involves a patient who assumes the sick role for personal satisfaction. Finally, Munchausen syndrome by proxy is similar to factitious disorder but involves a patient seeking the sick role vicariously through a second patient, often a child. By understanding the differences between these conditions, healthcare providers can provide appropriate care and treatment for their patients.
-
This question is part of the following fields:
- Psychiatry
-
-
Question 14
Correct
-
Which one of the following is not a notifiable disease in the United Kingdom?
Your Answer: HIV
Explanation:Notifying authorities about HIV is not required.
Notifiable Diseases in the UK
In the UK, certain diseases are considered notifiable, meaning that the Local Health Protection Team must be notified if a case is suspected or confirmed. The Proper Officer at the team will then inform the Health Protection Agency on a weekly basis. Notifiable diseases include acute encephalitis, acute infectious hepatitis, acute meningitis, acute poliomyelitis, anthrax, botulism, brucellosis, cholera, COVID-19, diphtheria, enteric fever, food poisoning, haemolytic uraemic syndrome, infectious bloody diarrhoea, invasive group A streptococcal disease, legionnaires disease, leprosy, malaria, measles, meningococcal septicaemia, mumps, plague, rabies, rubella, severe acute respiratory syndrome, scarlet fever, smallpox, tetanus, tuberculosis, typhus, viral haemorrhagic fever, whooping cough, and yellow fever.
It is important to note that HIV is not a notifiable disease in the UK, and in April 2010, dysentery, ophthalmia neonatorum, leptospirosis, and relapsing fever were removed from the list of notifiable diseases. The purpose of notifiable diseases is to monitor and control the spread of infectious diseases in the population. By requiring healthcare professionals to report cases, public health officials can track outbreaks and take appropriate measures to prevent further transmission.
-
This question is part of the following fields:
- Infectious Diseases
-
-
Question 15
Incorrect
-
A 14-year-old girl presents to her General Practitioner complaining of pain to the left knee which is worse after running. The knee is stiff in the morning and sometimes locks. There is a knee effusion present on examination and an X-ray shows a loose body in the knee joint.
Which of the following is the most likely diagnosis?
Your Answer: Osgood-Schlatter disease
Correct Answer: Osteochondritis dissecans
Explanation:Common Causes of Knee Pain in Adolescents and Young Adults
Knee pain is a common complaint among adolescents and young adults. There are several possible causes of knee pain, including osteochondritis dissecans, chondromalacia patellae, Osgood-Schlatter disease, osteoarthritis, and patellar dislocation.
Osteochondritis dissecans occurs when the articular cartilage separates from the joint surface, typically in the knee joint. This condition is common in teenagers and young adults and can cause vague, achy joint pain that worsens with activity. Other symptoms may include swelling, locking, catching, and giving way. Diagnosis is confirmed with an X-ray and magnetic resonance imaging can help with management and prognosis.
Chondromalacia patellae is characterized by abnormal softening of the cartilage on the underside of the patella. This condition is a common cause of chronic knee pain in teenagers and young adults. Symptoms include anterior knee pain that worsens after sitting for a prolonged period or walking down stairs. Diagnosis is made through examination and a positive shrug test.
Osgood-Schlatter disease is a cause of knee pain in young adolescents, particularly sporty boys. It is caused by overuse of the quadriceps, which strains the patellar ligament attachment to the tibia. Symptoms include pain inferior to the patella that worsens with activity and improves with rest. Diagnosis is usually clinical and treatment involves simple analgesics and ice packs.
Osteoarthritis is a disease of older age caused by degeneration of the articular cartilage. It is often seen in weight-bearing areas such as the knee and hip, but is unlikely in young adults.
Patellar dislocation is most common in teenage girls and often occurs during sports. Symptoms include sudden pain and an inability to weight bear on the affected side. Examination reveals a dislocated patella, often laterally, and an associated osteochondral fracture may be seen on an X-ray.
-
This question is part of the following fields:
- Musculoskeletal
-
-
Question 16
Correct
-
A 48-year-old man suffers an Achilles tendon rupture while playing basketball. He has never had any medical issues related to his muscles or bones. He recently began taking antibiotics for an infection and has been on them for the past week. What type of antibiotic is he likely taking?
Your Answer: Ciprofloxacin
Explanation:New-onset Achilles tendon disorders, including tendinitis and tendon rupture, are likely caused by ciprofloxacin, a medication with important side effects to consider.
Achilles tendon disorders are a common cause of pain in the back of the heel. These disorders can include tendinopathy, partial tears, and complete ruptures of the Achilles tendon. Certain factors, such as the use of quinolone antibiotics and high cholesterol levels, can increase the risk of developing these disorders. Symptoms of Achilles tendinopathy typically include gradual onset of pain that worsens with activity, as well as morning stiffness. Treatment for this condition usually involves pain relief, reducing activities that exacerbate the pain, and performing calf muscle eccentric exercises.
In contrast, an Achilles tendon rupture is a more serious condition that requires immediate medical attention. This type of injury is often caused by sudden, forceful movements during sports or running. Symptoms of an Achilles tendon rupture include an audible popping sound, sudden and severe pain in the calf or ankle, and an inability to walk or continue the activity. To help diagnose an Achilles tendon rupture, doctors may use Simmond’s triad, which involves examining the foot for abnormal angles and feeling for a gap in the tendon. Ultrasound is typically the first imaging test used to confirm a diagnosis of Achilles tendon rupture. If a rupture is suspected, it is important to seek medical attention from an orthopaedic specialist as soon as possible.
-
This question is part of the following fields:
- Musculoskeletal
-
-
Question 17
Correct
-
A 35-year-old gardener complains of a gradually worsening left elbow pain for the past two weeks. The pain intensifies when the elbow is straight and there is resistance during wrist extension and supination. What is the probable diagnosis?
Your Answer: Lateral epicondylitis
Explanation:The correct diagnosis is lateral epicondylitis, which is caused by repetitive arm movements. The pain is typically more severe when the wrist is extended against resistance and the elbow is straightened. This description does not match the symptoms of anterior interosseous syndrome, carpal tunnel syndrome, or medial epicondylitis.
Understanding Lateral Epicondylitis
Lateral epicondylitis, commonly known as tennis elbow, is a condition that often occurs after engaging in activities that the body is not accustomed to, such as painting or playing tennis. It is most prevalent in individuals aged 45-55 years and typically affects the dominant arm. The primary symptom of this condition is pain and tenderness localized to the lateral epicondyle. The pain is often exacerbated by wrist extension against resistance with the elbow extended or supination of the forearm with the elbow extended. Episodes of lateral epicondylitis can last between 6 months and 2 years, with patients experiencing acute pain for 6-12 weeks.
To manage lateral epicondylitis, it is essential to avoid muscle overload and engage in simple analgesia. Steroid injections and physiotherapy are also viable options for managing the condition. By understanding the symptoms and management options for lateral epicondylitis, individuals can take the necessary steps to alleviate pain and discomfort associated with this condition.
-
This question is part of the following fields:
- Musculoskeletal
-
-
Question 18
Incorrect
-
A 29-year-old woman arrives at the delivery ward for childbirth. She is 38 weeks pregnant and had an uncomplicated pregnancy. Her first child, who is now 2 years old, had neonatal sepsis due to Group B Streptococcus (GBS). She has no significant medical history. What is the best course of action for managing the risk of GBS?
Your Answer: Prescribe intrapartum intravenous benzylpenicillin and administer intravenous benzylpenicillin to the child at birth
Correct Answer: Prescribe intrapartum intravenous benzylpenicillin
Explanation:Women who have had a previous baby affected by early- or late-onset GBS disease should be offered maternal intravenous antibiotic prophylaxis. The recommended option is to prescribe intrapartum intravenous benzylpenicillin or ampicillin to the mother. This is according to the Royal College of Obstetricians and Gynaecologists guidelines published in 2017. Administering intravenous benzylpenicillin to the child at birth is not appropriate unless they show signs of neonatal sepsis. Prescribing intrapartum intravenous ceftazidime is also not recommended. Monitoring the newborn for signs of sepsis for the next 72 hours is not sufficient in this case. The best approach is to administer antibiotics to the mother to prevent the development of neonatal sepsis.
Group B Streptococcus (GBS) is a common cause of severe infection in newborns. It is estimated that 20-40% of mothers carry GBS in their bowel flora, which can be passed on to their infants during labor and lead to serious infections. Prematurity, prolonged rupture of membranes, previous sibling GBS infection, and maternal pyrexia are all risk factors for GBS infection. The Royal College of Obstetricians and Gynaecologists (RCOG) has published guidelines on GBS management, which include not offering universal screening for GBS to all women and not offering screening based on maternal request. Women who have had GBS detected in a previous pregnancy should be offered intrapartum antibiotic prophylaxis (IAP) or testing in late pregnancy and antibiotics if still positive. IAP should also be offered to women with a previous baby with GBS disease, women in preterm labor, and women with a fever during labor. Benzylpenicillin is the preferred antibiotic for GBS prophylaxis.
-
This question is part of the following fields:
- Reproductive Medicine
-
-
Question 19
Correct
-
A 75-year-old man presents to his GP with a decline in his vision. He describes a gradual onset of dark floaters in his vision over the past few months and has recently experienced some episodes of flashing lights when outside in bright sunlight. The patient has a history of hypertension, which is managed with 5mg ramipril daily. He has a smoking history of 45 pack-years, does not consume alcohol, and is able to perform his daily activities independently. What is the most probable diagnosis for this patient's vision changes?
Your Answer: Vitreous detachment
Explanation:The patient has flashers and floaters associated with vitreous detachment, which can lead to retinal detachment. This is not central retinal artery occlusion, ischaemic optic neuropathy, macular degeneration, or temporal arteritis.
Sudden loss of vision can be a scary symptom for patients, as it may indicate a serious issue or only be temporary. Transient monocular visual loss (TMVL) is a term used to describe a sudden, brief loss of vision that lasts less than 24 hours. The most common causes of sudden, painless loss of vision include ischaemic/vascular issues (such as thrombosis, embolism, and temporal arteritis), vitreous haemorrhage, retinal detachment, and retinal migraine.
Ischaemic/vascular issues, also known as ‘amaurosis fugax’, have a wide range of potential causes, including large artery disease, small artery occlusive disease, venous disease, and hypoperfusion. Altitudinal field defects are often seen, and ischaemic optic neuropathy can occur due to occlusion of the short posterior ciliary arteries. Central retinal vein occlusion is more common than arterial occlusion and can be caused by glaucoma, polycythaemia, or hypertension. Central retinal artery occlusion is typically caused by thromboembolism or arteritis and may present with an afferent pupillary defect and a ‘cherry red’ spot on a pale retina.
Vitreous haemorrhage can be caused by diabetes, bleeding disorders, or anticoagulants and may present with sudden visual loss and dark spots. Retinal detachment may be preceded by flashes of light or floaters, which are also common in posterior vitreous detachment. Differentiating between posterior vitreous detachment, retinal detachment, and vitreous haemorrhage can be challenging, but each has distinct features such as photopsia and floaters for posterior vitreous detachment, a dense shadow that progresses towards central vision for retinal detachment, and large bleeds causing sudden visual loss for vitreous haemorrhage.
-
This question is part of the following fields:
- Ophthalmology
-
-
Question 20
Correct
-
At the 4-month check, you observe bilateral hydroceles in a male infant. The swelling is limited to the scrotum and the testis can be felt in the scrotal sac. The infant is otherwise healthy and thriving. The mother expresses concern about the potential impact of the swelling on her son's fertility.
What is the best course of action for managing this situation?Your Answer: Reassure mum that hydroceles are common in infants and often self resolve
Explanation:It is common for newborn males to have communicating hydroceles, which usually resolve on their own. This is due to the processus vaginalis remaining open. Parents should be reassured that the hydroceles typically disappear within a few months. However, if the hydrocele persists beyond one year, it is recommended to refer the child to a urologist for possible repair. Ultrasound is not necessary to confirm the diagnosis. It is important to note that hydroceles do not impact fertility, but undescended testes can affect fertility if not treated.
Common Scrotal Problems and Their Features
Epididymal cysts, hydroceles, and varicoceles are the most common scrotal problems seen in primary care. Epididymal cysts are usually found posterior to the testicle and are separate from the body of the testicle. They may be associated with conditions such as polycystic kidney disease, cystic fibrosis, and von Hippel-Lindau syndrome. Diagnosis is confirmed by ultrasound, and management is usually supportive, although surgical removal or sclerotherapy may be attempted for larger or symptomatic cysts.
Hydroceles, on the other hand, describe the accumulation of fluid within the tunica vaginalis. They may be communicating or non-communicating, and may develop secondary to conditions such as epididymo-orchitis, testicular torsion, or testicular tumors. Hydroceles are usually soft, non-tender swellings of the hemi-scrotum that transilluminate with a pen torch. Diagnosis may be clinical, but ultrasound is required if there is any doubt about the diagnosis or if the underlying testis cannot be palpated. Management depends on the severity of the presentation, with infantile hydroceles generally repaired if they do not resolve spontaneously by the age of 1-2 years.
Varicoceles, on the other hand, are abnormal enlargements of the testicular veins that are usually asymptomatic but may be associated with subfertility. They are much more common on the left side and are classically described as a bag of worms. Diagnosis is confirmed by ultrasound with Doppler studies, and management is usually conservative, although surgery may be required if the patient is troubled by pain. There is ongoing debate regarding the effectiveness of surgery to treat infertility.
-
This question is part of the following fields:
- Renal Medicine/Urology
-
00
Correct
00
Incorrect
00
:
00
:
00
Session Time
00
:
00
Average Question Time (
Mins)