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  • Question 1 - A 32-year-old traveler returns from a visit to West Africa with frequent headaches...

    Correct

    • A 32-year-old traveler returns from a visit to West Africa with frequent headaches and occasional fevers. Laboratory tests reveal the presence of malaria. The patient is promptly initiated on treatment, but his condition worsens, leading to the development of jaundice, renal failure, and haemoglobinuria.

      What is the MOST LIKELY organism responsible for this illness?

      Your Answer: Plasmodium falciparum

      Explanation:

      Malaria is a contagious illness that is spread by female mosquitoes of the Anopheles genus. It is a parasitic infection caused by the Plasmodium genus. There are five species of Plasmodium that are known to cause disease in humans: Plasmodium falciparum, Plasmodium ovale, Plasmodium vivax, Plasmodium malariae, and Plasmodium knowlesi.

      The main symptom of malaria is the malarial paroxysm, which is a recurring pattern of symptoms. It begins with a cold phase, during which the patient experiences intense chills. This is followed by a hot stage, where the patient feels extremely hot. Finally, there is a sweating stage, during which the fever subsides and the patient sweats profusely. Upon examination, the patient may exhibit signs of anemia, jaundice, and have an enlarged liver and spleen, but there is no evidence of swollen lymph nodes.

      If a patient develops haemoglobinuria (the presence of hemoglobin in the urine) and renal failure after treatment, it may indicate a condition called blackwater fever, which is caused by Plasmodium falciparum. In this condition, an autoimmune reaction occurs between the parasite and quinine, leading to the destruction of red blood cells, hemoglobinuria, jaundice, and renal failure. Blackwater fever can be life-threatening.

    • This question is part of the following fields:

      • Infectious Diseases
      7.9
      Seconds
  • Question 2 - A 70-year-old man has loss of motivation, difficulties with concentration and behavioral changes...

    Incorrect

    • A 70-year-old man has loss of motivation, difficulties with concentration and behavioral changes that have been ongoing for the past few years. Over the past couple of months, he has also exhibited signs of memory loss. His family is extremely worried and states that his behavior has been very different from his usual self for the past few months. His language has become vulgar, and he has been somewhat lacking in inhibition. Occasionally, he has also been excessively active and prone to pacing and wandering.

      What is the SINGLE most probable diagnosis?

      Your Answer: Dementia with Lewy bodies (DLB)

      Correct Answer: Pick’s disease

      Explanation:

      Pick’s disease is a rare neurodegenerative disorder that leads to a gradual decline in cognitive function known as frontotemporal dementia. One of the key features of this condition is the accumulation of tau proteins in neurons, forming silver-staining, spherical aggregations called ‘Pick bodies.’

      Typically, Pick’s disease manifests between the ages of 40 and 60. Initially, individuals may experience changes in their personality, such as disinhibition, tactlessness, and vulgarity. They may also exhibit alterations in their moral values and attempt to distance themselves from their family. Difficulties with concentration, increased activity levels, pacing, and wandering are also common during this stage.

      What sets Pick’s disease apart from Alzheimer’s disease is that the changes in personality occur before memory loss becomes apparent. As the disease progresses, patients will experience deficits in intellect, memory, and language.

    • This question is part of the following fields:

      • Elderly Care / Frailty
      11.6
      Seconds
  • Question 3 - A 45-year-old woman develops hypothyroidism secondary to the administration of a medication for...

    Correct

    • A 45-year-old woman develops hypothyroidism secondary to the administration of a medication for a thyroid condition.

      Which of the following medications is most likely to be responsible?

      Your Answer: Amiodarone

      Explanation:

      Amiodarone has a chemical structure that is similar to thyroxine and has the ability to bind to the nuclear thyroid receptor. This medication has the potential to cause both hypothyroidism and hyperthyroidism, although hypothyroidism is more commonly observed, affecting around 5-10% of patients.

      There are several side effects associated with the use of amiodarone. These include the formation of microdeposits in the cornea, increased sensitivity to sunlight resulting in photosensitivity, feelings of nausea, disturbances in sleep patterns, and the development of either hyperthyroidism or hypothyroidism. In addition, there have been reported cases of acute hepatitis and jaundice, peripheral neuropathy, lung fibrosis, and QT prolongation.

      It is important to be aware of these potential side effects when considering the use of amiodarone as a treatment option. Regular monitoring and close medical supervision are necessary to detect and manage any adverse reactions that may occur.

    • This question is part of the following fields:

      • Pharmacology & Poisoning
      7.2
      Seconds
  • Question 4 - A patient with a history of recurrent episodes of painless rectal bleeding is...

    Incorrect

    • A patient with a history of recurrent episodes of painless rectal bleeding is found to have a Meckel's diverticulum during a colonoscopy.

      What is the most common location for Meckel's diverticulum?

      Your Answer: Duodenum

      Correct Answer: Ileum

      Explanation:

      A Meckel’s diverticulum is a leftover part of the vitellointestinal duct, which is no longer needed in the body. It is the most common abnormality in the gastrointestinal tract, found in about 2% of people. Interestingly, it is twice as likely to occur in men compared to women.

      When a Meckel’s diverticulum is present, it is usually located in the lower part of the small intestine, specifically within 60-100 cm (2 feet) of the ileocaecal valve. These diverticula are typically 3-6 cm (approximately 2 inches) long and may have a larger opening than the ileum.

      Meckel’s diverticula are often discovered incidentally, especially during an appendectomy. Most of the time, they do not cause any symptoms. However, they can lead to complications such as bleeding (25-50% of cases), intestinal blockage (10-40% of cases), diverticulitis, or perforation.

      These diverticula run in the opposite direction of the intestine’s natural folds but receive their blood supply from the ileum mesentery. They can be identified by a specific blood vessel called the vitelline artery. Typically, they are lined with the same type of tissue as the ileum, but they often contain abnormal tissue, with gastric tissue being the most common (50%) and pancreatic tissue being the second most common (5%). In rare cases, colonic or jejunal tissue may be present.

      To remember some key facts about Meckel’s diverticulum, the rule of 2s can be helpful:
      – It is found in 2% of the population.
      – It is more common in men, with a ratio of 2:1 compared to women.
      – It is located 2 feet away from the ileocaecal valve.
      – It is approximately 2 inches long.
      – It often contains two types of abnormal tissue: gastric and pancreatic.
      – The most common age for clinical presentation is 2 years old.

    • This question is part of the following fields:

      • Surgical Emergencies
      5.4
      Seconds
  • Question 5 - A 6-year-old boy is brought to the Emergency Department by his parents following...

    Incorrect

    • A 6-year-old boy is brought to the Emergency Department by his parents following a brief self-limiting seizure at home. He was diagnosed with strep throat by his pediatrician yesterday and started on antibiotics. Despite this, he has been experiencing intermittent high fevers throughout the day. After a thorough evaluation, you determine that he has had a febrile seizure.
      What is his estimated risk of developing epilepsy in the long term?

      Your Answer: 1%

      Correct Answer: 6%

      Explanation:

      Febrile convulsions are harmless, generalized seizures that occur in otherwise healthy children who have a fever due to an infection outside the brain. To diagnose febrile convulsions, the child must be developing normally, the seizure should last less than 20 minutes, have no complex features, and not cause any lasting abnormalities.

      The prognosis for febrile convulsions is generally positive. There is a 30 to 50% chance of experiencing recurrent febrile convulsions, with a 10% risk of recurrence within the first 24 hours. The likelihood of developing long-term epilepsy is around 6%.

      Complex febrile convulsions are characterized by certain factors. These include focal seizures, seizures lasting longer than 15 minutes, experiencing more than one convulsion during a single fever episode, or the child being left with a focal neurological deficit.

      Overall, febrile convulsions are typically harmless and do not cause any lasting damage.

    • This question is part of the following fields:

      • Neurology
      10.1
      Seconds
  • Question 6 - You review a 30-year-old woman with a history of a mental health disorder...

    Incorrect

    • You review a 30-year-old woman with a history of a mental health disorder and self-harming behavior. She is accompanied by the Police and has cut her arm with a sharp object. They would like you to assess her arm injuries and are concerned about her risk of future self-harm.
      When assessing this patient, which of the following features should your examination room have?

      Your Answer: A secure locking mechanism

      Correct Answer: An internal inspection window

      Explanation:

      When evaluating a disturbed or violent patient, your own safety should be the top priority. It is essential that the room you use for the examination has certain features to ensure your well-being. Firstly, there should be an internal inspection window that allows the staff to regularly check on both you and the patient. Additionally, the room should have an unimpeded exit, preferably with an outward opening door that is easy to exit through. It is also crucial to choose a room that is close to well-staffed areas, as this can provide immediate assistance if needed.

      It is highly recommended to avoid examining patients in isolated areas, as it significantly increases the risk of harm to the assessor. While the room should be comfortable, it is unnecessary to have excessive furnishings. In fact, having too much furniture and unnecessary equipment can pose a threat, as they can be used as weapons by the patient. Therefore, it is ideal to remove any excess furniture and unnecessary equipment from the room. In this case, an examination couch is not required and should be avoided, as it could potentially be used as a weapon.

      A secure locking mechanism is not necessary for the room, and it should be easily accessible to other staff members during the assessment. It is important to note that the room should not be used as a detainment area for the patient, and they should never be locked inside. By following these guidelines and ensuring the room has the recommended features, you can prioritize your safety while examining disturbed or violent patients.

    • This question is part of the following fields:

      • Mental Health
      18.7
      Seconds
  • Question 7 - A 45 year old male attends the emergency department and complains about fatigue,...

    Correct

    • A 45 year old male attends the emergency department and complains about fatigue, muscle spasms and frequent urination. A capillary blood glucose is normal at 4.4 mmol/l. You review his medication list and suspect the patient may have acquired diabetes insipidus. Which medication is most likely to be responsible?

      Your Answer: Lithium

      Explanation:

      Nephrogenic diabetes insipidus may develop in a certain percentage of individuals who take lithium.

      Further Reading:

      Diabetes insipidus (DI) is a condition characterized by either a decrease in the secretion of antidiuretic hormone (cranial DI) or insensitivity to antidiuretic hormone (nephrogenic DI). Antidiuretic hormone, also known as arginine vasopressin, is produced in the hypothalamus and released from the posterior pituitary. The typical biochemical disturbances seen in DI include elevated plasma osmolality, low urine osmolality, polyuria, and hypernatraemia.

      Cranial DI can be caused by various factors such as head injury, CNS infections, pituitary tumors, and pituitary surgery. Nephrogenic DI, on the other hand, can be genetic or result from electrolyte disturbances or the use of certain drugs. Symptoms of DI include polyuria, polydipsia, nocturia, signs of dehydration, and in children, irritability, failure to thrive, and fatigue.

      To diagnose DI, a 24-hour urine collection is done to confirm polyuria, and U&Es will typically show hypernatraemia. High plasma osmolality with low urine osmolality is also observed. Imaging studies such as MRI of the pituitary, hypothalamus, and surrounding tissues may be done, as well as a fluid deprivation test to evaluate the response to desmopressin.

      Management of cranial DI involves supplementation with desmopressin, a synthetic form of arginine vasopressin. However, hyponatraemia is a common side effect that needs to be monitored. In nephrogenic DI, desmopressin supplementation is usually not effective, and management focuses on ensuring adequate fluid intake to offset water loss and monitoring electrolyte levels. Causative drugs need to be stopped, and there is a risk of developing complications such as hydroureteronephrosis and an overdistended bladder.

    • This question is part of the following fields:

      • Endocrinology
      9.7
      Seconds
  • Question 8 - A 65-year-old woman comes in with a history of frequent falls, difficulty with...

    Incorrect

    • A 65-year-old woman comes in with a history of frequent falls, difficulty with walking, and urinary incontinence. After a thorough evaluation and tests, she is diagnosed with normal-pressure hydrocephalus.
      Which of the following medical interventions is most likely to be beneficial?

      Your Answer: Mannitol

      Correct Answer: Acetazolamide

      Explanation:

      This patient is displaying symptoms that are characteristic of normal-pressure hydrocephalus (NPH). NPH is a type of communicating hydrocephalus where the pressure inside the skull, as measured through lumbar puncture, is either normal or occasionally elevated. It primarily affects elderly individuals, and the likelihood of developing NPH increases with age.

      Around 50% of NPH cases are idiopathic, meaning that no clear cause can be identified. The remaining cases are secondary to various conditions such as head injury, meningitis, subarachnoid hemorrhage, central nervous system tumors, and radiotherapy.

      The typical presentation of NPH includes a classic triad of symptoms: gait disturbance (often characterized by a broad-based and shuffling gait), sphincter disturbance leading to incontinence (usually urinary incontinence), and progressive dementia with memory loss, inattention, inertia, and bradyphrenia.

      Diagnosing NPH primarily relies on identifying the classic clinical triad mentioned above. Additional investigations can provide supportive evidence and may involve CT and MRI scans, which reveal enlarged ventricles and periventricular lucency. Lumbar puncture can also be performed to assess cerebrospinal fluid (CSF) levels, which are typically normal or intermittently elevated. Intraventricular monitoring may show beta waves present for more than 5% of a 24-hour period.

      NPH is one of the few reversible causes of dementia, making early recognition and treatment crucial. Medical treatment options include the use of carbonic anhydrase inhibitors (such as acetazolamide) and repeated lumbar punctures as temporary measures. However, the definitive treatment for NPH involves surgically inserting a cerebrospinal fluid (CSF) shunt. This procedure provides lasting clinical benefits for 70% to 90% of patients compared to their pre-operative state.

    • This question is part of the following fields:

      • Elderly Care / Frailty
      12
      Seconds
  • Question 9 - A 62 year old male is brought into the emergency department by concerned...

    Correct

    • A 62 year old male is brought into the emergency department by concerned family members. They inform you that the patient is a heavy drinker but appeared very confused and disoriented, which is unusual for him. The patient scores 4/10 on the abbreviated mental test score (AMTS). Upon examination, you observe that the patient has yellowing of the eyes, shifting dullness on abdominal palpation, dilated abdominal veins, and asterixis. The patient's vital signs and initial blood tests are as follows:

      Blood pressure: 122/80 mmHg
      Pulse: 92 bpm
      Respiration rate: 18 bpm
      Temperature: 37.7ºC

      Bilirubin: 68 µmol/l
      ALP: 198 u/l
      ALT: 274 u/l
      Albumin: 26 g/l
      INR: 1.7

      What is the most likely diagnosis?

      Your Answer: Hepatic encephalopathy

      Explanation:

      Hepatic encephalopathy occurs when a person with liver disease experiences an episode where their brain function is affected. This happens because the liver is unable to properly process waste products, leading to an accumulation of nitrogenous waste in the body. These waste products then cross into the brain, where they cause changes in the brain’s osmotic pressure and disrupt neurotransmitter function. As a result, individuals may experience altered consciousness, behavior, and personality. Symptoms can range from confusion and forgetfulness to coma, and signs such as slurred speech and increased muscle tone may also be present. Hepatic encephalopathy is often triggered by factors like gastrointestinal bleeding, infections, or certain medications.

      Further Reading:

      Cirrhosis is a condition where the liver undergoes structural changes, resulting in dysfunction of its normal functions. It can be classified as either compensated or decompensated. Compensated cirrhosis refers to a stage where the liver can still function effectively with minimal symptoms, while decompensated cirrhosis is when the liver damage is severe and clinical complications are present.

      Cirrhosis develops over a period of several years due to repeated insults to the liver. Risk factors for cirrhosis include alcohol misuse, hepatitis B and C infection, obesity, type 2 diabetes, autoimmune liver disease, genetic conditions, certain medications, and other rare conditions.

      The prognosis of cirrhosis can be assessed using the Child-Pugh score, which predicts mortality based on parameters such as bilirubin levels, albumin levels, INR, ascites, and encephalopathy. The score ranges from A to C, with higher scores indicating a poorer prognosis.

      Complications of cirrhosis include portal hypertension, ascites, hepatic encephalopathy, variceal hemorrhage, increased infection risk, hepatocellular carcinoma, and cardiovascular complications.

      Diagnosis of cirrhosis is typically done through liver function tests, blood tests, viral hepatitis screening, and imaging techniques such as transient elastography or acoustic radiation force impulse imaging. Liver biopsy may also be performed in some cases.

      Management of cirrhosis involves treating the underlying cause, controlling risk factors, and monitoring for complications. Complications such as ascites, spontaneous bacterial peritonitis, oesophageal varices, and hepatic encephalopathy require specific management strategies.

      Overall, cirrhosis is a progressive condition that requires ongoing monitoring and management to prevent further complications and improve outcomes for patients.

    • This question is part of the following fields:

      • Gastroenterology & Hepatology
      6.8
      Seconds
  • Question 10 - A 7-year-old girl is brought to the Emergency Department by her father after...

    Correct

    • A 7-year-old girl is brought to the Emergency Department by her father after falling at a park. Her ankle appears to be deformed, and it is suspected that she has a fracture in her distal fibula. Her pain is evaluated using a numerical rating scale, and the triage nurse informs you that she is experiencing moderate pain.
      According to the RCEM guidance, which of the following analgesics is recommended for managing moderate pain in a child of this age?

      Your Answer: Rectal diclofenac 1 mg/kg

      Explanation:

      A recent audit conducted by the Royal College of Emergency Medicine (RCEM) in 2018 revealed a concerning decline in the standards of pain management for children with fractured limbs in Emergency Departments (EDs). The audit found that the majority of patients experienced longer waiting times for pain relief compared to previous years. Shockingly, more than 1 in 10 children who presented with significant pain due to a limb fracture did not receive any pain relief at all.

      To address this issue, the Agency for Health Care Policy and Research (AHCPR) in the USA recommends following the ABCs of pain management for all patients, including children. This approach involves regularly asking about pain, systematically assessing it, believing the patient and their family in their reports of pain and what relieves it, choosing appropriate pain control options, delivering interventions in a timely and coordinated manner, and empowering patients and their families to have control over their pain management.

      The RCEM has established standards that require a child’s pain to be assessed within 15 minutes of their arrival at the ED. This is considered a fundamental standard. Various rating scales are available for assessing pain in children, with the choice depending on the child’s age and ability to use the scale. These scales include the Wong-Baker Faces Pain Rating Scale, Numeric rating scale, and Behavioural scale.

      To ensure timely administration of analgesia to children in acute pain, the RCEM has set specific standards. These standards state that 100% of patients in severe pain should receive appropriate analgesia within 60 minutes of their arrival or triage, whichever comes first. Additionally, 75% should receive analgesia within 30 minutes, and 50% within 20 minutes.

    • This question is part of the following fields:

      • Pain & Sedation
      10.8
      Seconds
  • Question 11 - You diagnose a pediatric trauma patient with a right sided tension pneumothorax and...

    Correct

    • You diagnose a pediatric trauma patient with a right sided tension pneumothorax and plan to perform needle thoracentesis. Which of the following is the most appropriate anatomical landmark to use for needle insertion?

      Your Answer: 5th intercostal space midaxillary line

      Explanation:

      A pneumothorax is an abnormal collection of air in the pleural cavity of the lung. It can be classified by cause as primary spontaneous, secondary spontaneous, or traumatic. Primary spontaneous pneumothorax occurs without any obvious cause in the absence of underlying lung disease, while secondary spontaneous pneumothorax occurs in patients with significant underlying lung diseases. Traumatic pneumothorax is caused by trauma to the lung, often from blunt or penetrating chest wall injuries.

      Tension pneumothorax is a life-threatening condition where the collection of air in the pleural cavity expands and compresses normal lung tissue and mediastinal structures. It can be caused by any of the aforementioned types of pneumothorax. Immediate management of tension pneumothorax involves the ABCDE approach, which includes ensuring a patent airway, controlling the C-spine, providing supplemental oxygen, establishing IV access for fluid resuscitation, and assessing and managing other injuries.

      Treatment of tension pneumothorax involves needle thoracocentesis as a temporary measure to provide immediate decompression, followed by tube thoracostomy as definitive management. Needle thoracocentesis involves inserting a 14g cannula into the pleural space, typically via the 4th or 5th intercostal space midaxillary line. If the patient is peri-arrest, immediate thoracostomy is advised.

      The pathophysiology of tension pneumothorax involves disruption to the visceral or parietal pleura, allowing air to flow into the pleural space. This can occur through an injury to the lung parenchyma and visceral pleura, or through an entry wound to the external chest wall in the case of a sucking pneumothorax. Injured tissue forms a one-way valve, allowing air to enter the pleural space with inhalation but prohibiting air outflow. This leads to a progressive increase in the volume of non-absorbable intrapleural air with each inspiration, causing pleural volume and pressure to rise within the affected hemithorax.

    • This question is part of the following fields:

      • Resus
      9.7
      Seconds
  • Question 12 - A 32-year-old man recently suffered a fracture in his right wrist. His cast...

    Incorrect

    • A 32-year-old man recently suffered a fracture in his right wrist. His cast has been taken off, and he visits you with worries about his right hand. Since the fracture, he has experienced tingling sensations in his thumb and has accidentally dropped items from his right hand a few times. These symptoms have not shown any improvement after the removal of the cast.
      What is the MOST probable diagnosis?

      Your Answer: Carpal tunnel syndrome

      Correct Answer: Ulnar neuritis

      Explanation:

      Ulnar neuritis is characterized by hand clumsiness and can progress to muscle weakness and wasting in the ulnar nerve-supplied muscles. It may also cause numbness or tingling in the little finger and medial half of the ring finger. This condition is caused by the narrowing of the ulnar groove at the elbow and is associated with risk factors such as osteoarthritis, trauma, and rheumatoid arthritis. Nerve conduction studies and surgical decompression may be necessary for diagnosis and treatment.

      De Quervain’s tenosynovitis occurs when there is inflammation of the thumb extensor and abductor tendon sheaths. This leads to pain over the radial styloid, which worsens with forced adduction and flexion of the thumb. Treatment options include anti-inflammatory medications, thumb splints, and steroid injections.

      Dupuytren’s contracture occurs when the palmar fascia contracts, preventing finger extension. It commonly affects the fifth finger on the right hand and is more prevalent in men over the age of 65. Risk factors for this condition include male sex, family history, alcohol use, diabetes, smoking, trauma, and manual labor. Surgical release is necessary if the contracture affects daily activities or work.

      Trigger finger occurs when a nodule becomes stuck in the tendon sheath, causing the affected finger to remain in a fixed flexed position. The ring and middle fingers are most commonly affected, and risk factors include rheumatoid arthritis and diabetes. Steroid injections or surgical removal can be used to treat this condition.

      Carpal tunnel syndrome occurs when the median nerve is compressed under the flexor retinaculum, resulting in numbness, pain, and wasting of the thenar eminence in the lateral three and a half digits. Symptoms are often worse at night. While most cases are idiopathic, risk factors include obesity, oral contraceptive use, hypothyroidism, rheumatoid arthritis, pregnancy, diabetes, amyloidosis, acromegaly, tumors compressing the carpal tunnel, and previous wrist fractures. Tinel’s test and Phalen’s test can help diagnose carpal tunnel syndrome, and nerve conduction studies may be requested for further evaluation. Treatment options include splints, steroid injections, and surgical release if symptoms persist.

    • This question is part of the following fields:

      • Musculoskeletal (non-traumatic)
      22.1
      Seconds
  • Question 13 - A 25-year-old woman comes in seeking the morning after pill. She explains that...

    Correct

    • A 25-year-old woman comes in seeking the morning after pill. She explains that she had unprotected sexual intercourse (UPSI) with her long-term partner within the past 48 hours. She is in good health and is eager to resume taking the oral contraceptive pill after addressing this situation.
      What is the BEST choice for her in this case?

      Your Answer: Levonelle 1.5 mg

      Explanation:

      Women have three options when requesting emergency contraception. The first option is Levonelle 1.5 mg, which contains levonorgestrel and can be used up to 72 hours after unprotected sexual intercourse (UPSI). If vomiting occurs within 2 hours of taking the tablet, another one should be given. Levonelle mainly works by preventing ovulation.

      The second option is ulipristal acetate, the newest treatment available. It can be used up to 120 hours after UPSI. If vomiting occurs within 3 hours of ingestion, another tablet should be given. Ulipristal acetate also works by inhibiting ovulation. However, it should be avoided in patients taking enzyme-inducing drugs, those with severe hepatic impairment, or those with severe asthma requiring oral steroids.

      The third option is the copper IUD, which can be fitted up to 5 days after UPSI or ovulation, whichever is longer. The failure rate of the copper IUD is less than 1 in 1000, making it 10-20 times more effective than oral emergency contraceptive options. It is important to note that Levonelle and ulipristal may be less effective in women with higher BMIs.

    • This question is part of the following fields:

      • Sexual Health
      19.6
      Seconds
  • Question 14 - A child under your supervision is diagnosed with a reportable illness.
    Select from the...

    Correct

    • A child under your supervision is diagnosed with a reportable illness.
      Select from the options below the one condition that is currently a reportable illness.

      Your Answer: Scarlet fever

      Explanation:

      The Health Protection (Notification) Regulations currently require the reporting of certain diseases. These diseases include acute encephalitis, acute infectious hepatitis, acute meningitis, acute poliomyelitis, anthrax, botulism, brucellosis, cholera, COVID-19, diphtheria, enteric fever (typhoid or paratyphoid fever), food poisoning, haemolytic uraemic syndrome (HUS), infectious bloody diarrhoea, invasive group A streptococcal disease, Legionnaires’ Disease, leprosy, malaria, measles, meningococcal septicaemia, mumps, plague, rabies, rubella, SARS, scarlet fever, smallpox, tetanus, tuberculosis, typhus, viral haemorrhagic fever (VHF), whooping cough, and yellow fever.

    • This question is part of the following fields:

      • Infectious Diseases
      2.9
      Seconds
  • Question 15 - A 45-year-old man presents with brief episodes of vertigo that are worse in...

    Correct

    • A 45-year-old man presents with brief episodes of vertigo that are worse in the evening and is triggered by head movement and turning in bed. Each episode lasts only a couple of minutes. He experiences nausea during the attacks but has not vomited. He has no previous history of hearing loss or tinnitus.

      What is the SINGLE most probable diagnosis?

      Your Answer: Benign paroxysmal positional vertigo (BPPV)

      Explanation:

      Benign paroxysmal positional vertigo (BPPV) occurs when there is dysfunction in the inner ear. This dysfunction causes the otoliths, which are located in the utricle, to become dislodged from their normal position and migrate into one of the semicircular canals over time. As a result, these detached otoliths continue to move even after head movement has stopped, leading to vertigo due to the conflicting sensation of ongoing movement with other sensory inputs.

      While the majority of BPPV cases have no identifiable cause (idiopathic), approximately 40% of cases can be attributed to factors such as head injury, spontaneous labyrinthine degeneration, post-viral illness, middle ear surgery, or chronic middle ear disease.

      The main clinical features of BPPV include symptoms that are provoked by head movement, rolling over, and upward gaze. These episodes are typically brief, lasting less than 5 minutes, and are often worse in the mornings. Unlike other inner ear disorders, BPPV does not cause hearing loss or tinnitus. Nausea is a common symptom, while vomiting is rare. The Dix-Hallpike test can be used to confirm the diagnosis of BPPV.

      It is important to note that vestibular suppressant medications have not been proven to be beneficial in managing BPPV. These medications do not improve symptoms or reduce the duration of the disease.

      The treatment of choice for BPPV is the Epley manoeuvre. This maneuver aims to reposition the dislodged otoliths back into the utricles from the semicircular canals. A 2014 Cochrane review concluded that the Epley manoeuvre is a safe and effective treatment for BPPV, with a number needed to treat of 2-4.

      Referral to an ENT specialist is recommended for patients with BPPV in the following situations: if the treating clinician is unable to perform or access the Epley manoeuvre, if the Epley manoeuvre has not been beneficial after repeated attempts (minimum two), if the patient has been symptomatic for more than 4 weeks, or if the patient has experienced more than 3 episodes of BPPV.

    • This question is part of the following fields:

      • Ear, Nose & Throat
      7.4
      Seconds
  • Question 16 - You evaluate a 72-year-old woman with a painful swollen left big toe. The...

    Incorrect

    • You evaluate a 72-year-old woman with a painful swollen left big toe. The pain started this morning and is described as the most severe pain she has ever experienced. It has gradually worsened over the past 8 hours. She is unable to wear socks or shoes and had to come to the appointment in open-toe sandals. The overlying skin is red and shiny.

      She has a history of hypertension, which has been challenging to control. She is currently taking amlodipine 10 mg and ramipril 10 mg per day for this and is awaiting a review of her antihypertensive medication. Her blood pressure today is 165/94 mmHg.

      She has recently also been diagnosed with a myelodysplastic syndrome and requires regular blood transfusions. She is being monitored in a local hematology clinic for a low white cell count and thrombocytopenia.

      What is the most appropriate next step in management for this patient?

      Your Answer: Commence colchicine

      Correct Answer: Commence prednisolone

      Explanation:

      The diagnosis in this case is clearly gout. According to the European League Against Rheumatism (EULAR) guidelines, the development of sudden joint pain accompanied by swelling, tenderness, and redness, which worsens over a period of 6-12 hours, strongly suggests crystal arthropathy.

      Checking serum urate levels to confirm high levels of uric acid before starting treatment for acute gout attacks is not very beneficial and should not delay treatment. While these levels can be useful for monitoring treatment response, they often decrease during an acute attack and can even be normal. If levels are checked and found to be normal during an attack, they should be rechecked once the attack has resolved.

      The first-line treatment for acute gout attacks is non-steroidal anti-inflammatory drugs (NSAIDs) like naproxen. However, caution should be exercised when using NSAIDs in patients with a history of hypertension. Since this patient has had difficulty controlling their blood pressure and remains hypertensive, it would be wise to avoid NSAIDs in this case.

      Colchicine is an effective alternative for treating gout, although it may take longer to take effect. It is often used in patients who cannot take NSAIDs due to contraindications, such as hypertension or a history of peptic ulcer disease. It’s important to note that colchicine can also affect the bone marrow, leading to an increase in white blood cells and a decrease in platelets. Therefore, it should not be used in patients with blood disorders, as in this case.

      During an acute gout attack, allopurinol should not be used as it can prolong the attack and even trigger another acute attack. If a patient is already taking allopurinol, it should be continued, and the acute attack should be treated with NSAIDs, colchicine, or corticosteroids as appropriate.

      Corticosteroids are an effective alternative for managing acute gout in patients who cannot take NSAIDs or colchicine. They can be administered orally, intramuscularly, intravenously, or directly into the affected joint. In this patient’s case, using corticosteroids would be the safest and most reasonable treatment option.

    • This question is part of the following fields:

      • Musculoskeletal (non-traumatic)
      22.4
      Seconds
  • Question 17 - You are asked to assess an older patient who has fainted. They have...

    Correct

    • You are asked to assess an older patient who has fainted. They have a bradyarrhythmia evident on their ECG, and you determine to administer a dose of atropine.
      Which ONE statement about the use of atropine is accurate?

      Your Answer: It blocks the effects of the vagus nerve on both the SA and AV nodes

      Explanation:

      Atropine acts as an antagonist to the parasympathetic neurotransmitter acetylcholine at muscarinic receptors. This means that it blocks the effects of the vagus nerve on both the SA node and the AV node, resulting in increased sinus automaticity and improved AV node conduction.

      The side effects of atropine are dependent on the dosage and may include dry mouth, nausea and vomiting, blurred vision, urinary retention, and tachyarrhythmias. Elderly patients may also experience acute confusion and hallucinations.

      Atropine is recommended for use in cases of sinus, atrial, or nodal bradycardia or AV block when the patient’s hemodynamic condition is unstable due to the bradycardia. According to the ALS bradycardia algorithm, an initial dose of 500 mcg IV is suggested if any adverse features such as shock, syncope, myocardial ischemia, or heart failure are present. If this initial dose is unsuccessful, additional 500 mcg doses can be administered at 3-5 minute intervals, with a maximum dose of 3 mg. It is important to avoid doses exceeding 3 mg as they can paradoxically slow the heart rate.

      Asystole during cardiac arrest is typically caused by primary myocardial pathology rather than excessive vagal tone. Therefore, there is no evidence supporting the routine use of atropine in the treatment of asystole or PEA. Consequently, atropine is no longer included in the non-shockable part of the ALS algorithm.

      Aside from its use in cardiac conditions, atropine also has other applications. It can be used topically in the eyes as a cycloplegic and mydriatic, to reduce secretions during anesthesia, and in the treatment of organophosphate poisoning.

    • This question is part of the following fields:

      • Cardiology
      12.8
      Seconds
  • Question 18 - A 65-year-old woman with a history of chronic alcohol abuse is diagnosed with...

    Incorrect

    • A 65-year-old woman with a history of chronic alcohol abuse is diagnosed with Wernicke's encephalopathy. You have been requested to assess the patient.
      Which of the following symptoms is MOST LIKELY to be observed?

      Your Answer: Retrograde amnesia

      Correct Answer: Ataxia

      Explanation:

      Wernicke’s encephalopathy is a condition that is commonly associated with alcohol abuse and other causes of thiamine deficiency. It is characterized by a classic triad of symptoms, including acute confusion, ophthalmoplegia (paralysis or weakness of the eye muscles), and ataxia (loss of coordination). Additional possible features of this condition may include papilloedema (swelling of the optic disc), hearing loss, apathy, dysphagia (difficulty swallowing), memory impairment, and hypothermia. The majority of cases also experience peripheral neuropathy, which typically affects the legs.

      The condition is marked by acute capillary haemorrhages, astrocytosis (increase in the number of astrocytes, a type of brain cell), and neuronal death in the upper brainstem and diencephalon. These abnormalities can be visualized using MRI scanning, while CT scanning is not very useful for diagnosis.

      If left untreated, most patients with Wernicke’s encephalopathy will go on to develop a Korsakoff psychosis. This condition is characterized by retrograde amnesia (loss of memory for events that occurred before the onset of amnesia), an inability to form new memories, disordered time perception, and confabulation (fabrication of false memories).

      When Wernicke’s encephalopathy is suspected, it is crucial to administer parenteral thiamine (such as Pabrinex) for at least 5 days. Following the parenteral therapy, oral thiamine should be continued.

    • This question is part of the following fields:

      • Neurology
      9.6
      Seconds
  • Question 19 - You assess a client who has recently developed severe depression and contemplate the...

    Incorrect

    • You assess a client who has recently developed severe depression and contemplate the potential presence of an underlying physiological factor contributing to this condition.
      Which ONE of the following is NOT a potential physiological cause for depression?

      Your Answer: Chronic obstructive pulmonary disease

      Correct Answer: Thiamine deficiency

      Explanation:

      Thiamine deficiency is linked to episodes of acute confusion, but it is not typically associated with depression. On the other hand, depression is commonly seen in individuals with hypercalcemia. Chronic diseases like Parkinson’s disease and COPD are strongly correlated with depression. Additionally, both psychosis and depression can be associated with the use of steroids.

    • This question is part of the following fields:

      • Mental Health
      15.2
      Seconds
  • Question 20 - A middle-aged man who lives by himself is brought to the Emergency Department...

    Correct

    • A middle-aged man who lives by himself is brought to the Emergency Department by his brother; he feels excessively warm and is extremely thirsty. He feels nauseated but has not vomited yet. His core temperature is currently 40.2°C, and his heart rate is 106 bpm. He is fully conscious, and his GCS is 15. There is currently a heatwave during the summer, and he has been at home alone in a poorly ventilated apartment.
      What is the MOST probable diagnosis?

      Your Answer: Heat exhaustion

      Explanation:

      Heat exhaustion typically comes before heat stroke. If left untreated, heat exhaustion often progresses to heat stroke. The body’s ability to dissipate heat is still functioning, and the body temperature is usually below 41°C. Common symptoms include nausea, decreased urine output, weakness, headache, thirst, and a fast heart rate. The central nervous system is usually unaffected. Patients often complain of feeling hot and appear flushed and sweaty.

      Heat cramps are characterized by intense thirst and muscle cramps. Body temperature is often elevated but usually remains below 40°C. Sweating, heat dissipation mechanisms, and cognitive function are preserved, and there is no neurological impairment.

      Heat stroke is defined as a systemic inflammatory response with a core temperature above 40.6°C, accompanied by changes in mental state and varying levels of organ dysfunction. Typical symptoms of heat stroke include:

      – Core temperature above 40.6°C
      – Early symptoms include extreme fatigue, headache, fainting, flushed face, vomiting, and diarrhea
      – The skin is usually hot and dry
      – Sweating may occur in about 50% of cases of exertional heat stroke
      – The loss of the ability to sweat is a late and concerning sign
      – Hyperventilation is almost always present
      – Cardiovascular dysfunction, such as irregular heart rhythms, low blood pressure, and shock
      – Respiratory dysfunction, including acute respiratory distress syndrome (ARDS)
      – Central nervous system dysfunction, including seizures and coma
      – If the temperature rises above 41.5°C, multiple organ failure, coagulopathy, and rhabdomyolysis can occur

      Malignant hypothermia and neuroleptic malignant syndrome are highly unlikely in this case, as the patient has no recent history of general anesthesia or taking phenothiazines or other antipsychotics, respectively.

    • This question is part of the following fields:

      • Environmental Emergencies
      10.5
      Seconds
  • Question 21 - A 4-year-old child is brought in by ambulance. He has been experiencing seizures...

    Incorrect

    • A 4-year-old child is brought in by ambulance. He has been experiencing seizures for the past 35 minutes. So far, he has received two doses of IV lorazepam. His bowel movement is normal. He has a history of epilepsy and is on phenytoin as maintenance therapy.

      According to the current APLS guidelines, what would be the most suitable next step in managing his condition?

      Your Answer: Set up phenytoin infusion

      Correct Answer: Set up phenobarbitone infusion

      Explanation:

      The current algorithm for the treatment of a convulsing child, known as APLS, is as follows:

      Step 1 (5 minutes after the start of convulsion):
      If a child has been convulsing for 5 minutes or more, the initial dose of benzodiazepine should be administered. This can be done by giving Lorazepam at a dose of 0.1 mg/kg intravenously (IV) or intraosseously (IO) if vascular access is available. Alternatively, buccal midazolam at a dose of 0.5 mg/kg or rectal diazepam at a dose of 0.5 mg/kg can be given if vascular access is not available.

      Step 2 (10 minutes after the start of Step 1):
      If the convulsion continues for a further 10 minutes, a second dose of benzodiazepine should be given. It is also important to summon senior help at this point.

      Step 3 (10 minutes after the start of Step 2):
      At this stage, it is necessary to involve senior help to reassess the child and provide guidance on further management. The recommended approach is as follows:
      – If the child is not already on phenytoin, a phenytoin infusion should be initiated. This involves administering 20 mg/kg of phenytoin intravenously over a period of 20 minutes.
      – If the child is already taking phenytoin, phenobarbitone can be used as an alternative. The recommended dose is 20 mg/kg administered intravenously over 20 minutes.
      – In the meantime, rectal paraldehyde can be considered at a dose of 0.8 ml/kg of the 50:50 mixture while preparing the infusion.

      Step 4 (20 minutes after the start of Step 3):
      If the child is still experiencing convulsions at this stage, it is crucial to have an anaesthetist present. A rapid sequence induction with thiopental is recommended for further management.

      Please note that this algorithm is subject to change based on individual patient circumstances and the guidance of medical professionals.

    • This question is part of the following fields:

      • Neurology
      16.3
      Seconds
  • Question 22 - A 40-year-old woman comes in with tremors, anxiety, sweating, and nausea. Her vital...

    Incorrect

    • A 40-year-old woman comes in with tremors, anxiety, sweating, and nausea. Her vital signs reveal an elevated heart rate of 119 bpm. She typically consumes 2-3 large bottles of strong cider daily but has recently run out of money and has not had an alcoholic beverage since the previous evening.
      Which ONE of the following medications, not belonging to the benzodiazepine class, is commonly prescribed in the UK for the treatment of alcohol withdrawal symptoms?

      Your Answer: Chlordiazepoxide

      Correct Answer: Carbamazepine

      Explanation:

      Benzodiazepines are commonly used in the UK to manage symptoms of alcohol withdrawal. Currently, only diazepam and chlordiazepoxide have been authorized for this purpose. Other benzodiazepines like alprazolam, clobazam, and lorazepam do not currently have authorization for treating alcohol withdrawal symptoms in the UK.

      Carbamazepine is also used in the UK to manage alcohol-related withdrawal symptoms, but it does not have official authorization for this use.

      Clomethiazole, on the other hand, does have UK marketing authorization for treating alcohol withdrawal symptoms, but it is only recommended for use in a hospital setting with close supervision. The product information for clomethiazole advises caution when prescribing it to individuals with a history of addiction or outpatient alcoholics. It is also not recommended for patients who continue to drink or abuse alcohol. Combining alcohol with clomethiazole, especially in alcoholics with cirrhosis, can lead to fatal respiratory depression even with short-term use. Therefore, clomethiazole should only be used in a hospital under close supervision or, in rare cases, by specialist units on an outpatient basis with careful monitoring of the daily dosage.

    • This question is part of the following fields:

      • Mental Health
      12.2
      Seconds
  • Question 23 - A 22-year-old individual comes in with a painful, itchy, red left eye. During...

    Correct

    • A 22-year-old individual comes in with a painful, itchy, red left eye. During the examination, there is noticeable redness in the conjunctiva, and follicles are observed on the inner eyelid when it is turned inside out. They recently had a mild and short-lived upper respiratory tract infection, but there are no other significant medical history.

      What is the MOST LIKELY diagnosis for this patient?

      Your Answer: Viral conjunctivitis

      Explanation:

      Conjunctivitis is the most common reason for red eyes, accounting for about 35% of all eye problems seen in general practice. It occurs when the conjunctiva, the thin layer covering the white part of the eye, becomes inflamed. Conjunctivitis can be caused by an infection or an allergic reaction.

      Infective conjunctivitis is inflammation of the conjunctiva caused by a viral, bacterial, or parasitic infection. The most common type of infective conjunctivitis is viral, with adenoviruses being the main culprits. Bacterial conjunctivitis is also common and is usually caused by Streptococcus pneumoniae, Staphylococcus aureus, or Haemophilus influenzae.

      The symptoms of infective conjunctivitis include sudden redness of the conjunctiva, discomfort described as a gritty or burning sensation, watering of the eyes, and discharge that may temporarily blurry vision. It can be challenging to differentiate between viral and bacterial conjunctivitis based on symptoms alone.

      Here are some key features that can help distinguish between viral and bacterial conjunctivitis:

      Features suggestive of viral conjunctivitis:
      – Mild to moderate redness of the conjunctiva
      – Presence of follicles on the inner surface of the eyelids
      – Swelling of the eyelids
      – Small, pinpoint bleeding under the conjunctiva
      – Pseudomembranes (thin layers of tissue) may form on the inner surface of the eyelids in severe cases, often caused by adenovirus
      – Less discharge (usually watery) compared to bacterial conjunctivitis
      – Mild to moderate itching
      – Symptoms of upper respiratory tract infection and swollen lymph nodes in front of the ears

      Features suggestive of bacterial conjunctivitis:
      – Purulent or mucopurulent discharge with crusting of the eyelids, which may cause them to stick together upon waking
      – Mild or no itching
      – Swollen lymph nodes in front of the ears, which are often present in severe bacterial conjunctivitis
      – If the discharge is copious and mucopurulent, infection with Neisseria gonorrhoeae should be considered.

      By considering these distinguishing features, healthcare professionals can better diagnose and manage cases of conjunctivitis.

    • This question is part of the following fields:

      • Ophthalmology
      12.9
      Seconds
  • Question 24 - A 68 year old male presents to the emergency department with a 4...

    Incorrect

    • A 68 year old male presents to the emergency department with a 4 day history of colicky abdominal pain and diarrhea. The patient reports feeling worse in the past 24 hours, although the diarrhea has stopped as he last had a bowel movement more than 12 hours ago. The patient visited his primary care physician 2 days ago, who requested a stool sample. The patient's vital signs are as follows:

      Temperature: 38.8ºC
      Blood pressure: 98/78 mmHg
      Pulse: 106 bpm
      Respiration rate: 18

      Upon reviewing the pathology results, it is noted that the stool sample has tested positive for clostridium difficile. Additionally, the patient's complete blood count, which was sent by the triage nurse, is available and shown below:

      Hemoglobin: 12.4 g/l
      Platelets: 388 * 109/l
      White blood cells: 23.7 * 109/l

      How would you classify the severity of this patient's clostridium difficile infection?

      Your Answer: Severe

      Correct Answer: Life threatening

      Explanation:

      Clostridium difficile (C.diff) is a gram positive rod commonly found in hospitals. Some strains of C.diff produce exotoxins that can cause intestinal damage, leading to pseudomembranous colitis. This infection can range from mild diarrhea to severe illness. Antibiotic-associated diarrhea is often caused by C.diff, with 20-30% of cases being attributed to this bacteria. Antibiotics such as clindamycin, cephalosporins, fluoroquinolones, and broad-spectrum penicillins are frequently associated with C.diff infection.

      Clinical features of C.diff infection include diarrhea, distinctive smell, abdominal pain, raised white blood cell count, and in severe cases, toxic megacolon. In some severe cases, diarrhea may be absent due to the infection causing paralytic ileus. Diagnosis is made by detecting Clostridium difficile toxin (CDT) in the stool. There are two types of exotoxins produced by C.diff, toxin A and toxin B, which cause mucosal damage and the formation of a pseudomembrane in the colon.

      Risk factors for developing C.diff infection include age over 65, antibiotic treatment, previous C.diff infection, exposure to infected individuals, proton pump inhibitor or H2 receptor antagonist use, prolonged hospitalization or residence in a nursing home, and chronic disease or immunosuppression. Complications of C.diff infection can include toxic megacolon, colon perforation, sepsis, and even death, especially in frail elderly individuals.

      Management of C.diff infection involves stopping the causative antibiotic if possible, optimizing hydration with IV fluids if necessary, and assessing the severity of the infection. Treatment options vary based on severity, ranging from no antibiotics for mild cases to vancomycin or fidaxomicin for moderate cases, and hospital protocol antibiotics (such as oral vancomycin with IV metronidazole) for severe or life-threatening cases. Severe cases may require admission under gastroenterology or GI surgeons.

    • This question is part of the following fields:

      • Gastroenterology & Hepatology
      15.2
      Seconds
  • Question 25 - A 35-year-old patient with a history of schizophrenia comes in with side effects...

    Incorrect

    • A 35-year-old patient with a history of schizophrenia comes in with side effects from a medication that he recently began taking for this condition. Upon examination, you observe that he is experiencing severe muscular rigidity, a decreased level of consciousness, and a body temperature of 40ºC.
      Which of the following medications is most likely causing these symptoms?

      Your Answer: Amitriptyline

      Correct Answer: Chlorpromazine

      Explanation:

      First-generation antipsychotics, also known as conventional or typical antipsychotics, are potent blockers of dopamine D2 receptors. However, these drugs also have varying effects on other receptors such as serotonin type 2 (5-HT2), alpha1, histaminic, and muscarinic receptors.

      One of the major drawbacks of first-generation antipsychotics is their high incidence of extrapyramidal side effects. These include rigidity, bradykinesia, dystonias, tremor, akathisia, and tardive dyskinesia. Additionally, there is a rare but life-threatening reaction called neuroleptic malignant syndrome (NMS) that can occur with these medications. NMS is characterized by fever, muscle rigidity, altered mental status, and autonomic dysfunction. It typically occurs shortly after starting or increasing the dose of a neuroleptic medication.

      In contrast, second-generation antipsychotics, also known as novel or atypical antipsychotics, have a lower risk of extrapyramidal side effects and NMS compared to their first-generation counterparts. However, they are associated with higher rates of metabolic effects and weight gain.

      It is important to differentiate serotonin syndrome from NMS as they share similar features. Serotonin syndrome is most commonly caused by serotonin-specific reuptake inhibitors.

      Here are some commonly encountered examples of first- and second-generation antipsychotics:

      First-generation:
      – Chlopromazine
      – Haloperidol
      – Fluphenazine
      – Trifluoperazine

      Second-generation:
      – Clozapine
      – Olanzapine
      – Quetiapine
      – Risperidone
      – Aripiprazole

    • This question is part of the following fields:

      • Pharmacology & Poisoning
      4.8
      Seconds
  • Question 26 - A 25 year old female has been brought into the emergency department (ED)...

    Incorrect

    • A 25 year old female has been brought into the emergency department (ED) in the early hours of the morning after being discovered unresponsive in a parking lot behind a nightclub by the authorities. The paramedics initiated cardiopulmonary resuscitation (CPR) which has been ongoing since the patient's arrival in the ED. The patient's core temperature is recorded at 28ºC. You contemplate the most effective Rewarming strategy to employ. Which method of Rewarming is known for producing a rapid increase in core body temperature?

      Your Answer:

      Correct Answer: Cardiopulmonary bypass

      Explanation:

      Cardiopulmonary bypass (CPB) is the most efficient technique for warming up a patient who is experiencing hypothermia. While other methods may also be suitable and may have already been initiated by the paramedic team, CPB stands out as the most effective approach.

      Further Reading:

      Hypothermic cardiac arrest is a rare situation that requires a tailored approach. Resuscitation is typically prolonged, but the prognosis for young, previously healthy individuals can be good. Hypothermic cardiac arrest may be associated with drowning. Hypothermia is defined as a core temperature below 35ºC and can be graded as mild, moderate, severe, or profound based on the core temperature. When the core temperature drops, basal metabolic rate falls and cell signaling between neurons decreases, leading to reduced tissue perfusion. Signs and symptoms of hypothermia progress as the core temperature drops, initially presenting as compensatory increases in heart rate and shivering, but eventually ceasing as the temperature drops into moderate hypothermia territory.

      ECG changes associated with hypothermia include bradyarrhythmias, Osborn waves, prolonged PR, QRS, and QT intervals, shivering artifact, ventricular ectopics, and cardiac arrest. When managing hypothermic cardiac arrest, ALS should be initiated as per the standard ALS algorithm, but with modifications. It is important to check for signs of life, re-warm the patient, consider mechanical ventilation due to chest wall stiffness, adjust dosing or withhold drugs due to slowed drug metabolism, and correct electrolyte disturbances. The resuscitation of hypothermic patients is often prolonged and may continue for a number of hours.

      Pulse checks during CPR may be difficult due to low blood pressure, and the pulse check is prolonged to 1 minute for this reason. Drug metabolism is slowed in hypothermic patients, leading to a build-up of potentially toxic plasma concentrations of administered drugs. Current guidance advises withholding drugs if the core temperature is below 30ºC and doubling the drug interval at core temperatures between 30 and 35ºC. Electrolyte disturbances are common in hypothermic patients, and it is important to interpret results keeping the setting in mind. Hypoglycemia should be treated, hypokalemia will often correct as the patient re-warms, ABG analyzers may not reflect the reality of the hypothermic patient, and severe hyperkalemia is a poor prognostic indicator.

      Different warming measures can be used to increase the core body temperature, including external passive measures such as removal of wet clothes and insulation with blankets, external active measures such as forced heated air or hot-water immersion, and internal active measures such as inhalation of warm air, warmed intravenous fluids, gastric, bladder, peritoneal and/or pleural lavage and high volume renal haemofilter.

    • This question is part of the following fields:

      • Environmental Emergencies
      0
      Seconds
  • Question 27 - Following a postnatal home visit, the community midwife refers a newborn baby with...

    Incorrect

    • Following a postnatal home visit, the community midwife refers a newborn baby with jaundice. The pediatric team conducts an assessment and investigations, revealing unconjugated hyperbilirubinemia. The suspected underlying cause is extrinsic hemolysis. Which of the following is the most likely diagnosis?

      Your Answer:

      Correct Answer: Haemolytic disease of the newborn

      Explanation:

      Neonatal jaundice is a complex subject, and it is crucial for candidates to have knowledge about the different causes, presentations, and management of conditions that lead to jaundice in newborns. Neonatal jaundice can be divided into two groups: unconjugated hyperbilirubinemia, which can be either physiological or pathological, and conjugated hyperbilirubinemia, which is always pathological.

      The causes of neonatal jaundice can be categorized as follows:

      Haemolytic unconjugated hyperbilirubinemia:
      – Intrinsic causes of haemolysis include hereditary spherocytosis, G6PD deficiency, sickle-cell disease, and pyruvate kinase deficiency.
      – Extrinsic causes of haemolysis include haemolytic disease of the newborn and Rhesus disease.

      Non-haemolytic unconjugated hyperbilirubinemia:
      – Breastmilk jaundice, cephalhaematoma, polycythemia, infection (particularly urinary tract infections), Gilbert syndrome.

      Hepatic conjugated hyperbilirubinemia:
      – Hepatitis A and B, TORCH infections, galactosaemia, alpha 1-antitrypsin deficiency, drugs.

      Post-hepatic conjugated hyperbilirubinemia:
      – Biliary atresia, bile duct obstruction, choledochal cysts.

      By understanding these different categories and their respective examples, candidates will be better equipped to handle neonatal jaundice cases.

    • This question is part of the following fields:

      • Neonatal Emergencies
      0
      Seconds
  • Question 28 - A 35-year-old woman came in ten days ago with a fever, tenderness in...

    Incorrect

    • A 35-year-old woman came in ten days ago with a fever, tenderness in the suprapubic area, and discharge from the vagina. The doctors diagnosed her with pelvic inflammatory disease and started her on antibiotics. She initially got better, but now she is back with intense pain in her lower abdomen and a temperature of 39.5°C.

      What is the SINGLE most probable diagnosis?

      Your Answer:

      Correct Answer: Tubo-ovarian abscess

      Explanation:

      This patient is highly likely to have developed a tubo-ovarian abscess (TOA), which is a complication of pelvic inflammatory disease. TOA occurs when a pocket of pus forms in the fallopian tube and/or ovary. If the abscess ruptures, it can lead to sepsis and become life-threatening.

      The initial imaging modality of choice is transabdominal and endovaginal ultrasound. This imaging technique often reveals multilocular complex retro-uterine/adnexal masses with debris, septations, and irregular thick walls. These masses can be present on both sides.

      Urgent hospital admission is necessary, and the usual management involves draining the abscess and administering intravenous antibiotics. The abscess drainage can be guided by ultrasound or CT scanning.

      In some cases, laparotomy or laparoscopy may be required to drain the abscess.

    • This question is part of the following fields:

      • Obstetrics & Gynaecology
      0
      Seconds
  • Question 29 - You are part of the team managing a conscious patient in the emergency...

    Incorrect

    • You are part of the team managing a conscious patient in the emergency room. You decide to insert a nasopharyngeal airway adjunct. How should you determine the appropriate size of the nasopharyngeal airway?

      Your Answer:

      Correct Answer: Sized according to the distance between the nostril and the tragus of the ear

      Explanation:

      Nasopharyngeal airway adjuncts (NPAs) are selected based on their length, which should match the distance between the nostril and the tragus of the ear.

      Further Reading:

      Techniques to keep the airway open:

      1. Suction: Used to remove obstructing material such as blood, vomit, secretions, and food debris from the oral cavity.

      2. Chin lift manoeuvres: Involves lifting the head off the floor and lifting the chin to extend the head in relation to the neck. Improves alignment of the pharyngeal, laryngeal, and oral axes.

      3. Jaw thrust: Used in trauma patients with cervical spine injury concerns. Fingers are placed under the mandible and gently pushed upward.

      Airway adjuncts:

      1. Oropharyngeal airway (OPA): Prevents the tongue from occluding the airway. Sized according to the patient by measuring from the incisor teeth to the angle of the mandible. Inserted with the tip facing backwards and rotated 180 degrees once it touches the back of the palate or oropharynx.

      2. Nasopharyngeal airway (NPA): Useful when it is difficult to open the mouth or in semi-conscious patients. Sized by length (distance between nostril and tragus of the ear) and diameter (roughly that of the patient’s little finger). Contraindicated in basal skull and midface fractures.

      Laryngeal mask airway (LMA):

      – Supraglottic airway device used as a first line or rescue airway.
      – Easy to insert, sized according to patient’s bodyweight.
      – Advantages: Easy insertion, effective ventilation, some protection from aspiration.
      – Disadvantages: Risk of hypoventilation, greater gastric inflation than endotracheal tube (ETT), risk of aspiration and laryngospasm.

      Note: Proper training and assessment of the patient’s condition are essential for airway management.

    • This question is part of the following fields:

      • Basic Anaesthetics
      0
      Seconds
  • Question 30 - A 60-year-old woman is found to have immunoglobulin light chains in her urine.
    Which...

    Incorrect

    • A 60-year-old woman is found to have immunoglobulin light chains in her urine.
      Which of the following is the MOST LIKELY diagnosis?

      Your Answer:

      Correct Answer: Multiple myeloma

      Explanation:

      Immunoglobulin light chains that are present in the urine are commonly known as Bence-Jones proteins (BJP). These proteins are primarily observed in individuals with multiple myeloma, although they can occasionally be detected in Waldenström macroglobulinemia, although this is a rare occurrence. It is important to note that BJP in the urine is not observed in the other conditions mentioned in this question.

    • This question is part of the following fields:

      • Haematology
      0
      Seconds
  • Question 31 - You are with a hiking group at an elevation of 3100 meters. One...

    Incorrect

    • You are with a hiking group at an elevation of 3100 meters. One of your members, who is experiencing a headache, nausea, and fatigue, is diagnosed with acute mountain sickness (AMS). Which medication would be the most suitable for treating AMS?

      Your Answer:

      Correct Answer: Dexamethasone

      Explanation:

      Dexamethasone is the preferred medication for treating Acute Mountain Sickness (AMS) and High Altitude Cerebral Edema (HACE). In cases of mild AMS, simply halting the ascent and giving the body time to acclimatize may be sufficient. However, if mild AMS persists or worsens, or if the patient experiences moderate to severe AMS, descending to a lower altitude is the most effective treatment, preferably with the addition of supplemental oxygen. Dexamethasone is the recommended medication for managing both AMS and HACE.

      Further Reading:

      High Altitude Illnesses

      Altitude & Hypoxia:
      – As altitude increases, atmospheric pressure decreases and inspired oxygen pressure falls.
      – Hypoxia occurs at altitude due to decreased inspired oxygen.
      – At 5500m, inspired oxygen is approximately half that at sea level, and at 8900m, it is less than a third.

      Acute Mountain Sickness (AMS):
      – AMS is a clinical syndrome caused by hypoxia at altitude.
      – Symptoms include headache, anorexia, sleep disturbance, nausea, dizziness, fatigue, malaise, and shortness of breath.
      – Symptoms usually occur after 6-12 hours above 2500m.
      – Risk factors for AMS include previous AMS, fast ascent, sleeping at altitude, and age <50 years old.
      – The Lake Louise AMS score is used to assess the severity of AMS.
      – Treatment involves stopping ascent, maintaining hydration, and using medication for symptom relief.
      – Medications for moderate to severe symptoms include dexamethasone and acetazolamide.
      – Gradual ascent, hydration, and avoiding alcohol can help prevent AMS.

      High Altitude Pulmonary Edema (HAPE):
      – HAPE is a progression of AMS but can occur without AMS symptoms.
      – It is the leading cause of death related to altitude illness.
      – Risk factors for HAPE include rate of ascent, intensity of exercise, absolute altitude, and individual susceptibility.
      – Symptoms include dyspnea, cough, chest tightness, poor exercise tolerance, cyanosis, low oxygen saturations, tachycardia, tachypnea, crepitations, and orthopnea.
      – Management involves immediate descent, supplemental oxygen, keeping warm, and medication such as nifedipine.

      High Altitude Cerebral Edema (HACE):
      – HACE is thought to result from vasogenic edema and increased vascular pressure.
      – It occurs 2-4 days after ascent and is associated with moderate to severe AMS symptoms.
      – Symptoms include headache, hallucinations, disorientation, confusion, ataxia, drowsiness, seizures, and manifestations of raised intracranial pressure.
      – Immediate descent is crucial for management, and portable hyperbaric therapy may be used if descent is not possible.
      – Medication for treatment includes dexamethasone and supplemental oxygen. Acetazolamide is typically used for prophylaxis.

    • This question is part of the following fields:

      • Environmental Emergencies
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  • Question 32 - A 9-month-old girl comes in with a significant haemarthrosis in her left knee...

    Incorrect

    • A 9-month-old girl comes in with a significant haemarthrosis in her left knee after falling while trying to stand up using a side table. Her mother mentions that her older sister has a bleeding disorder and has also had haemarthrosis before.
      What is the MOST probable diagnosis?

      Your Answer:

      Correct Answer: Haemophilia A

      Explanation:

      Haemophilia is a collection of genetic disorders that are inherited and lead to impaired blood clotting. Haemophilia A specifically occurs when there is a deficiency of factor VIII and is typically passed down as a recessive trait on the X chromosome.

      The initial signs of haemophilia A usually appear around 6 months of age when infants start crawling, although it can manifest later. Bleeding can occur either spontaneously or as a result of trauma. One key indicator of haemophilia is bleeding into muscles and joints, known as haemarthrosis. While gastrointestinal and cerebral bleeding can also happen, they are less common occurrences.

      Based on the symptoms described, the most likely diagnosis from the given options would be Haemophilia A, especially when there is a combination of haemarthrosis and an older brother with the same disorder.

      Idiopathic thrombocytopenic purpura (ITP) is a condition where the immune system causes a decrease in platelet count. Antibodies target the glycoprotein IIb-IIIa or Ib complex. Acute ITP is more prevalent in children and affects both sexes equally. Chronic ITP, on the other hand, is more common in young to middle-aged women. Unlike haemophilia, ITP typically presents with symptoms such as nosebleeds, oral bleeding, purpura, or petechiae, rather than haemarthrosis. Additionally, ITP is not an inherited disorder.

      Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited disorder that follows an X-linked recessive pattern. It is characterized by a defect in the G6PD enzyme, which plays a crucial role in red blood cell metabolism. Most individuals with G6PD deficiency do not experience symptoms. However, haemolytic crisis can occur in response to factors like illness (especially infection and diabetic ketoacidosis), certain medications (such as specific antibiotics, antimalarials, sulphonamides, and aspirin), or certain foods (notably fava beans).

      Von Willebrand disease (vWD) is the most common hereditary coagulation disorder, affecting approximately 1 in 100 individuals. It arises from a deficiency in Von Willebrand factor (vWF), which leads to reduced levels of factor VIII. vWF is responsible for protecting factor VIII from rapid breakdown in the blood and is also necessary for platelet adhesion.

    • This question is part of the following fields:

      • Haematology
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  • Question 33 - A 32 year old female presents to the emergency department after an explosion...

    Incorrect

    • A 32 year old female presents to the emergency department after an explosion occurred in her garage. The patient reports inhaling fumes and experiencing symptoms of nausea and dizziness since then. While triaging the patient, law enforcement officers arrive to interview her and inform you that the patient seemed to be operating a methamphetamine lab in her garage, which contained various dangerous chemicals. Your plan is to initiate decontamination procedures. Which of the following methods has been proven to eliminate up to 90% of the contamination?

      Your Answer:

      Correct Answer: Removal of patient clothing to underwear

      Explanation:

      To remove contaminated material, it is recommended to remove and dispose of clothing. It is important to seal the clothing and treat it as hazardous waste. If wet decontamination is being utilized, patients should shower using warm water and detergent.

      Further Reading:

      Chemical incidents can occur as a result of leaks, spills, explosions, fires, terrorism, or the use of chemicals during wars. Industrial sites that use chemicals are required to conduct risk assessments and have accident plans in place for such incidents. Health services are responsible for decontamination, unless mass casualties are involved, and all acute health trusts must have major incident plans in place.

      When responding to a chemical incident, hospitals prioritize containment of the incident and prevention of secondary contamination, triage with basic first aid, decontamination if not done at the scene, recognition and management of toxidromes (symptoms caused by exposure to specific toxins), appropriate supportive or antidotal treatment, transfer to definitive treatment, a safe end to the hospital response, and continuation of business after the event.

      To obtain advice when dealing with chemical incidents, the two main bodies are Toxbase and the National Poisons Information Service. Signage on containers carrying chemicals and material safety data sheets (MSDS) accompanying chemicals also provide information on the chemical contents and their hazards.

      Contamination in chemical incidents can occur in three phases: primary contamination from the initial incident, secondary contamination spread via contaminated people leaving the initial scene, and tertiary contamination spread to the environment, including becoming airborne and waterborne. The ideal personal protective equipment (PPE) for chemical incidents is an all-in-one chemical-resistant overall with integral head/visor and hands/feet worn with a mask, gloves, and boots.

      Decontamination of contaminated individuals involves the removal and disposal of contaminated clothing, followed by either dry or wet decontamination. Dry decontamination is suitable for patients contaminated with non-caustic chemicals and involves blotting and rubbing exposed skin gently with dry absorbent material. Wet decontamination is suitable for patients contaminated with caustic chemicals and involves a warm water shower while cleaning the body with simple detergent.

      After decontamination, the focus shifts to assessing the extent of any possible poisoning and managing it. The patient’s history should establish the chemical the patient was exposed to, the volume and concentration of the chemical, the route of exposure, any protective measures in place, and any treatment given. Most chemical poisonings require supportive care using standard resuscitation principles, while some chemicals have specific antidotes. Identifying toxidromes can be useful in guiding treatment, and specific antidotes may be administered accordingly.

    • This question is part of the following fields:

      • Environmental Emergencies
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  • Question 34 - A 4 year old female is brought into the emergency department by concerned...

    Incorrect

    • A 4 year old female is brought into the emergency department by concerned parents. They inform you that the patient started vomiting yesterday and has had multiple episodes of diarrhea since then. The patient has been drinking less than usual and has vomited after being given a drink. The parents mention that there has been no recent travel and that the patient's immunizations are up to date. On examination, the patient has dry lips and buccal mucosa. The abdomen is soft, but the child becomes irritable when the abdomen is palpated. The peripheries are warm with a capillary refill time of 2.5 seconds. The patient's vital signs are as follows:

      Pulse: 146 bpm
      Respiration rate: 32 bpm
      Temperature: 37.9ºC

      What is the most likely diagnosis?

      Your Answer:

      Correct Answer: Viral gastroenteritis

      Explanation:

      Based on the given information, the most likely diagnosis for the 4-year-old female patient is viral gastroenteritis. This is supported by the symptoms of vomiting and diarrhea, as well as the fact that the patient has been drinking less than usual and has vomited after being given a drink. The absence of recent travel and up-to-date immunizations also suggest that this is a viral rather than a bacterial infection.

      Further Reading:

      Gastroenteritis is a common condition in children, particularly those under the age of 5. It is characterized by the sudden onset of diarrhea, with or without vomiting. The most common cause of gastroenteritis in infants and young children is rotavirus, although other viruses, bacteria, and parasites can also be responsible. Prior to the introduction of the rotavirus vaccine in 2013, rotavirus was the leading cause of gastroenteritis in children under 5 in the UK. However, the vaccine has led to a significant decrease in cases, with a drop of over 70% in subsequent years.

      Norovirus is the most common cause of gastroenteritis in adults, but it also accounts for a significant number of cases in children. In England & Wales, there are approximately 8,000 cases of norovirus each year, with 15-20% of these cases occurring in children under 9.

      When assessing a child with gastroenteritis, it is important to consider whether there may be another more serious underlying cause for their symptoms. Dehydration assessment is also crucial, as some children may require intravenous fluids. The NICE traffic light system can be used to identify the risk of serious illness in children under 5.

      In terms of investigations, stool microbiological testing may be indicated in certain cases, such as when the patient has been abroad, if diarrhea lasts for more than 7 days, or if there is uncertainty over the diagnosis. U&Es may be necessary if intravenous fluid therapy is required or if there are symptoms and/or signs suggestive of hypernatremia. Blood cultures may be indicated if sepsis is suspected or if antibiotic therapy is planned.

      Fluid management is a key aspect of treating children with gastroenteritis. In children without clinical dehydration, normal oral fluid intake should be encouraged, and oral rehydration solution (ORS) supplements may be considered. For children with dehydration, ORS solution is the preferred method of rehydration, unless intravenous fluid therapy is necessary. Intravenous fluids may be required for children with shock or those who are unable to tolerate ORS solution.

      Antibiotics are generally not required for gastroenteritis in children, as most cases are viral or self-limiting. However, there are some exceptions, such as suspected or confirmed sepsis, Extraintestinal spread of bacterial infection, or specific infections like Clostridium difficile-associated pseudomembranous enterocolitis or giardiasis.

    • This question is part of the following fields:

      • Paediatric Emergencies
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  • Question 35 - A 35 year old male presents to the emergency department with a laceration...

    Incorrect

    • A 35 year old male presents to the emergency department with a laceration on his forearm caused by a broken glass. You intend to clean and examine the wound using local anesthesia. The patient's weight is recorded as 70kg. What is the maximum amount of 1% lidocaine you should administer to this patient?

      Your Answer:

      Correct Answer: 16.5 ml

      Explanation:

      The concentration of the solution is 10 mg/mL, meaning there are 10 milligrams of the active ingredient in every milliliter of the solution. The maximum recommended dose for an adult is 16.5 mL. However, when performing a digital ring block, it is typically only necessary to use 2-3 mL of the local anesthetic solution, which is a much smaller amount compared to the maximum dose.

      Further Reading:

      Digital nerve blocks are commonly used to numb the finger for various procedures such as foreign body removal, dislocation reduction, and suturing. Sensation to the finger is primarily provided by the proper digital nerves, which arise from the common digital nerve. Each common digital nerve divides into two proper digital nerves, which run along the palmar aspect of the finger. These proper digital nerves give off a dorsal branch that supplies the dorsal aspect of the finger.

      The most common technique for digital nerve blocks is the digital (ring) block. The hand is cleaned and the injection sites are cleansed with an alcohol swab. A syringe containing 1% lidocaine is prepared, and the needle is inserted at the base of the finger from a dorsal approach. Lidocaine is infiltrated under the skin, and the needle is then advanced towards the palmar aspect of the finger to inject more lidocaine. This process is repeated on the opposite side of the finger.

      It is important not to use lidocaine with adrenaline for this procedure, as it may cause constriction and ischemia of the digital artery. Lidocaine 1% is the preferred local anesthetic, and the maximum dose is 3 ml/kg up to 200 mg. Contraindications for digital nerve blocks include compromised circulation to the finger, infection at the planned injection site, contraindication to local anesthetic (e.g. allergy), and suspected compartment syndrome (which is rare in the finger).

      Complications of digital nerve blocks can include vascular injury to the digital artery or vein, injury to the digital nerve, infection, pain, allergic reaction, intravascular injection (which can be avoided by aspirating prior to injection), and systemic local anesthetic toxicity (which is uncommon with typical doses of lidocaine).

    • This question is part of the following fields:

      • Pain & Sedation
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  • Question 36 - A 28-year-old woman who is 8-weeks pregnant is brought to the hospital due...

    Incorrect

    • A 28-year-old woman who is 8-weeks pregnant is brought to the hospital due to hyperemesis gravidarum.
      Which of the following is the LEAST probable complication associated with this condition?

      Your Answer:

      Correct Answer: Hyperkalaemia

      Explanation:

      Vomiting is a common occurrence during the early stages of pregnancy, typically happening between 7 and 12 weeks. However, there is a more severe form called hyperemesis gravidarum, which affects less than 1% of pregnancies. This condition is characterized by uncontrollable and intense nausea and vomiting, leading to imbalances in fluids and electrolytes, significant ketonuria, nutritional deficiencies, and weight loss.

      Hyperemesis gravidarum can result in electrolyte imbalances, particularly hyponatremia and hypokalemia. However, it does not cause hyperkalemia. This persistent vomiting can also lead to other complications such as dehydration, acidosis, deficiencies in vitamins B1, B12, and B6, Mallory-Weiss tears, retinal hemorrhages, pneumothorax, prematurity, and small-for-gestational age babies.

    • This question is part of the following fields:

      • Obstetrics & Gynaecology
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  • Question 37 - You are evaluating a 70-year-old individual in the emergency department. Laboratory results indicate...

    Incorrect

    • You are evaluating a 70-year-old individual in the emergency department. Laboratory results indicate a serum potassium level of 6.9 mmol/L. An electrocardiogram (ECG) is conducted. Which of the subsequent ECG alterations is linked to hyperkalemia?

      Your Answer:

      Correct Answer: P-wave flattening

      Explanation:

      Hyperkalaemia, a condition characterized by high levels of potassium in the blood, can be identified through specific changes seen on an electrocardiogram (ECG). One of these changes is the tenting of T-waves, where the T-waves become tall and pointed. Additionally, the P-wave, which represents atrial depolarization, may widen and flatten. Other ECG changes associated with hyperkalaemia include a prolonged PR interval, flat P-waves, wide P-waves, widened QRS complex, the appearance of a sine wave pattern, and the possibility of heart block.

      Further Reading:

      Vasoactive drugs can be classified into three categories: inotropes, vasopressors, and unclassified. Inotropes are drugs that alter the force of muscular contraction, particularly in the heart. They primarily stimulate adrenergic receptors and increase myocardial contractility. Commonly used inotropes include adrenaline, dobutamine, dopamine, isoprenaline, and ephedrine.

      Vasopressors, on the other hand, increase systemic vascular resistance (SVR) by stimulating alpha-1 receptors, causing vasoconstriction. This leads to an increase in blood pressure. Commonly used vasopressors include norepinephrine, metaraminol, phenylephrine, and vasopressin.

      Electrolytes, such as potassium, are essential for proper bodily function. Solutions containing potassium are often given to patients to prevent or treat hypokalemia (low potassium levels). However, administering too much potassium can lead to hyperkalemia (high potassium levels), which can cause dangerous arrhythmias. It is important to monitor potassium levels and administer it at a controlled rate to avoid complications.

      Hyperkalemia can be caused by various factors, including excessive potassium intake, decreased renal excretion, endocrine disorders, certain medications, metabolic acidosis, tissue destruction, and massive blood transfusion. It can present with cardiovascular, respiratory, gastrointestinal, and neuromuscular symptoms. ECG changes, such as tall tented T-waves, prolonged PR interval, flat P-waves, widened QRS complex, and sine wave, are also characteristic of hyperkalemia.

      In summary, vasoactive drugs can be categorized as inotropes, vasopressors, or unclassified. Inotropes increase myocardial contractility, while vasopressors increase systemic vascular resistance. Electrolytes, particularly potassium, are important for bodily function, but administering too much can lead to hyperkalemia. Monitoring potassium levels and ECG changes is crucial in managing hyperkalemia.

    • This question is part of the following fields:

      • Elderly Care / Frailty
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  • Question 38 - A 72 year old female arrives at the emergency department after speaking with...

    Incorrect

    • A 72 year old female arrives at the emergency department after speaking with her primary care physician over the phone. She explains that while she was shopping, her right arm and right leg suddenly felt weak and became a bit difficult to move. The patient is otherwise alert, oriented, feels well, and has normal speech. A brain CT scan reveals a focal area of ischemia consistent with an acute stroke. You arrange for her transfer to the stroke unit. The patient inquires if she can drive her car before going to the ward. What advice would you give her regarding driving?

      Your Answer:

      Correct Answer: Advise them, they must not drive a car for at least 1 month following a confirmed stroke

      Explanation:

      Patients who have experienced a stroke should be aware that they are not allowed to drive for at least one month if they have a type 1 license. If there are no neurological issues after this time period, they may not need to inform the DVLA (Driver and Vehicle Licensing Agency). However, they must inform the DVLA if any of the following conditions apply: they have had more than one stroke or transient ischemic attack (TIA), they have a Group 2 license, a medical practitioner has expressed concerns about their ability to drive, they still have residual deficits one month after the stroke (such as weakness in the limbs, visual problems, coordination difficulties, memory or understanding issues), the stroke required neurosurgical treatment, or if they experienced a seizure (unless it was an isolated seizure within 24 hours of the stroke and there is no history of prior seizures).

      Further Reading:

      Blackouts are a common occurrence in the emergency department and can have serious consequences if they happen while a person is driving. It is crucial for doctors in the ED to be familiar with the guidelines set by the DVLA (Driver and Vehicle Licensing Agency) regarding driving restrictions for patients who have experienced a blackout.

      The DVLA has specific rules for different types of conditions that may cause syncope (loss of consciousness). For group 1 license holders (car/motorcycle use), if a person has had a first unprovoked isolated seizure, they must refrain from driving for 6 months or 12 months if there is an underlying causative factor that may increase the risk. They must also notify the DVLA. For group 2 license holders (bus and heavy goods vehicles), the restrictions are more stringent, with a requirement of 12 months off driving for a first unprovoked isolated seizure and 5 years off driving if there is an underlying causative factor.

      For epilepsy or multiple seizures, both group 1 and group 2 license holders must remain seizure-free for 12 months before their license can be considered. They must also notify the DVLA. In the case of a stroke or isolated transient ischemic attack (TIA), group 1 license holders need to refrain from driving for 1 month, while group 2 license holders must wait for 12 months before being re-licensed subject to medical evaluation. Multiple TIAs require 3 months off driving for both groups.

      Isolated vasovagal syncope requires no driving restriction for group 1 license holders, but group 2 license holders must refrain from driving for 3 months. Both groups must notify the DVLA. If syncope is caused by a reversible and treated condition, group 1 license holders need 4 weeks off driving, while group 2 license holders require 3 months. In the case of an isolated syncopal episode with an unknown cause, group 1 license holders must refrain from driving for 6 months, while group 2 license holders will have their license refused or revoked for 12 months.

      For patients who continue to drive against medical advice, the GMC (General Medical Council) has provided guidance on how doctors should manage the situation. Doctors should explain to the patient why they are not allowed to drive and inform them of their legal duty to notify the DVLA or DVA (Driver and Vehicle Agency in Northern Ireland). Doctors should also record the advice given to the patient in their medical record

    • This question is part of the following fields:

      • Neurology
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  • Question 39 - Which of the following organizations is classified as a Category 2 entity according...

    Incorrect

    • Which of the following organizations is classified as a Category 2 entity according to the Civil Contingencies Act 2004 in the UK?

      Your Answer:

      Correct Answer: The Health and Safety Executive

      Explanation:

      The Civil Contingencies Act 2004 establishes a framework for civil protection in the United Kingdom. This legislation categorizes local responders to major incidents into two groups, each with their own set of responsibilities.

      Category 1 responders consist of organizations that play a central role in responding to most emergencies, such as the emergency services, local authorities, and NHS bodies. These Category 1 responders are obligated to fulfill a comprehensive range of civil protection duties. These duties include assessing the likelihood of emergencies occurring and using this information to inform contingency planning. They must also develop emergency plans, establish business continuity management arrangements, and ensure that information regarding civil protection matters is readily available to the public. Additionally, Category 1 responders are responsible for maintaining systems to warn, inform, and advise the public in the event of an emergency. They are expected to share information with other local responders to enhance coordination and efficiency. Furthermore, local authorities within this category are required to provide guidance and support to businesses and voluntary organizations regarding business continuity management.

      On the other hand, Category 2 organizations, such as the Health and Safety Executive, transport companies, and utility companies, are considered co-operating bodies. While they may not be directly involved in the core planning work, they play a crucial role in incidents that impact their respective sectors. Category 2 responders have a more limited set of duties, primarily focused on cooperating and sharing relevant information with both Category 1 and Category 2 responders.

      For more information on this topic, please refer to the Civil Contingencies Act 2004.

    • This question is part of the following fields:

      • Major Incident Management & PHEM
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  • Question 40 - A 60-year-old woman comes in with a red, hot, swollen great toe. The...

    Incorrect

    • A 60-year-old woman comes in with a red, hot, swollen great toe. The diagnosis is acute gout. You decide to start her on a non-steroidal anti-inflammatory drug (NSAID). Her husband was recently diagnosed with a peptic ulcer after an endoscopy, and she is worried about the potential side effects of NSAIDs.
      Which of the following NSAIDs has the lowest occurrence of side effects?

      Your Answer:

      Correct Answer: Ibuprofen

      Explanation:

      The differences in anti-inflammatory activity among NSAIDs are minimal, but there is significant variation in how individuals respond to and tolerate these drugs. Approximately 60% of patients will experience a positive response to any NSAID, and those who do not respond to one may find relief with another. Pain relief typically begins shortly after taking the first dose, and a full analgesic effect is usually achieved within a week. However, it may take up to 3 weeks to see an anti-inflammatory effect, which may not be easily assessed. If desired results are not achieved within these timeframes, it is recommended to try a different NSAID.

      NSAIDs work by reducing the production of prostaglandins through the inhibition of the enzyme cyclo-oxygenase. Different NSAIDs vary in their selectivity for inhibiting different types of cyclo-oxygenase. Selective inhibition of cyclo-oxygenase-2 is associated with a lower risk of gastrointestinal intolerance. Other factors also play a role in susceptibility to gastrointestinal effects, so the choice of NSAID should consider the incidence of gastrointestinal and other side effects.

      Ibuprofen, a propionic acid derivative, possesses anti-inflammatory, analgesic, and antipyretic properties. It generally has fewer side effects compared to other non-selective NSAIDs, but its anti-inflammatory properties are weaker. For rheumatoid arthritis, doses of 1.6 to 2.4 g daily are required, and it may not be suitable for conditions where inflammation is prominent, such as acute gout.

      Naproxen is often a preferred choice due to its combination of good efficacy and low incidence of side effects. However, it does have a higher occurrence of side effects compared to ibuprofen.

      Ketoprofen and diclofenac have similar anti-inflammatory properties to ibuprofen but are associated with more side effects.

      Indometacin has an action that is equal to or superior to naproxen, but it also has a high incidence of side effects, including headache, dizziness, and gastrointestinal disturbances.

    • This question is part of the following fields:

      • Pharmacology & Poisoning
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  • Question 41 - A 2 year old is brought to the emergency department by his father...

    Incorrect

    • A 2 year old is brought to the emergency department by his father due to a 24 hour history of worsening left sided otalgia and high temperature. During examination, a bulging red tympanic membrane is observed and acute otitis media is diagnosed.

      What is the most probable causative organism in this case?

      Your Answer:

      Correct Answer: Streptococcus pneumoniae

      Explanation:

      The most probable causative organism in this case is Streptococcus pneumoniae. This bacterium is a common cause of acute otitis media, especially in young children. It is known to cause infection in the middle ear, leading to symptoms such as ear pain (otalgia), fever, and a red, bulging tympanic membrane. Other organisms such as Escherichia coli, Candida albicans, Pseudomonas aeruginosa, and Staphylococcus aureus can also cause ear infections, but Streptococcus pneumoniae is the most likely culprit in this particular case.

      Further Reading:

      Acute otitis media (AOM) is an inflammation in the middle ear accompanied by symptoms and signs of an ear infection. It is commonly seen in young children below 4 years of age, with the highest incidence occurring between 9 to 15 months of age. AOM can be caused by viral or bacterial pathogens, and co-infection with both is common. The most common viral pathogens include respiratory syncytial virus (RSV), rhinovirus, adenovirus, influenza virus, and parainfluenza virus. The most common bacterial pathogens include Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pyogenes.

      Clinical features of AOM include ear pain (otalgia), fever, a red or cloudy tympanic membrane, and a bulging tympanic membrane with loss of anatomical landmarks. In young children, symptoms may also include crying, grabbing or rubbing the affected ear, restlessness, and poor feeding.

      Most children with AOM will recover within 3 days without treatment. Serious complications are rare but can include persistent otitis media with effusion, recurrence of infection, temporary hearing loss, tympanic membrane perforation, labyrinthitis, mastoiditis, meningitis, intracranial abscess, sinus thrombosis, and facial nerve paralysis.

      Management of AOM involves determining whether admission to the hospital is necessary based on the severity of systemic infection or suspected acute complications. For patients who do not require admission, regular pain relief with paracetamol or ibuprofen is advised. Decongestants or antihistamines are not recommended. Antibiotics may be offered immediately for patients who are systemically unwell, have symptoms and signs of a more serious illness or condition, or have a high risk of complications. For other patients, a decision needs to be made on the antibiotic strategy, considering the rarity of acute complications and the possible adverse effects of antibiotics. Options include no antibiotic prescription with advice to seek medical help if symptoms worsen rapidly or significantly, a back-up antibiotic prescription to be used if symptoms do not improve within 3 days, or an immediate antibiotic prescription with advice to seek medical advice if symptoms worsen rapidly or significantly.

      The first-line antibiotic choice for AOM is a 5-7 day course of amoxicillin. For individuals allergic to or intolerant of penicillin, clarithromycin or erythromycin a 5–7 day course of clarithromycin or erythromycin (erythromycin is preferred in pregnant women).

    • This question is part of the following fields:

      • Ear, Nose & Throat
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  • Question 42 - A patient presents with fatigue, loss of appetite, yellowing of the skin, and...

    Incorrect

    • A patient presents with fatigue, loss of appetite, yellowing of the skin, and pain in the upper right side of the abdomen. The doctor suspects a diagnosis of acute hepatitis B.
      Which of the following blood test results is most indicative of an acute hepatitis B infection?

      Your Answer:

      Correct Answer: HBsAg positive, IgM anti-HBc positive

      Explanation:

      Hepatitis B surface antigen (HBsAg) is a protein found on the surface of the hepatitis B virus. It can be detected in high levels in the blood during both acute and chronic hepatitis B virus infections. The presence of HBsAg indicates that the person is capable of spreading the infection to others. Normally, the body produces antibodies to HBsAg as part of the immune response to the infection. HBsAg is also used to create the hepatitis B vaccine.

      Hepatitis B surface antibody (anti-HBs) indicates that a person has recovered from the hepatitis B virus infection and is now immune to it. This antibody can also develop in individuals who have been successfully vaccinated against hepatitis B.

      Total hepatitis B core antibody (anti-HBc) appears when symptoms of acute hepatitis B begin and remains present for life. The presence of anti-HBc indicates that a person has either had a previous or ongoing infection with the hepatitis B virus, although the exact time frame cannot be determined. This antibody is not present in individuals who have received the hepatitis B vaccine.

      IgM antibody to hepatitis B core antigen (IgM anti-HBc) indicates a recent infection or acute hepatitis B. If this antibody is present, it suggests that the infection occurred within the past six months.

    • This question is part of the following fields:

      • Gastroenterology & Hepatology
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  • Question 43 - A 16 year old girl arrives at the emergency department with her friend...

    Incorrect

    • A 16 year old girl arrives at the emergency department with her friend following a fall from her skateboard. An X-ray reveals a dislocated shoulder. You inform the patient that the shoulder will require sedation for reduction. At what age is it generally assumed that a patient has the capacity to provide consent for treatment?

      Your Answer:

      Correct Answer: 16

      Explanation:

      Patients who are 16 years old and above are presumed to have the ability to make decisions about their treatment.

      Further Reading:

      Patients have the right to determine what happens to their own bodies, and for consent to be valid, certain criteria must be met. These criteria include the person being informed about the intervention, having the capacity to consent, and giving consent voluntarily and freely without any pressure or undue influence.

      In order for a person to be deemed to have capacity to make a decision on a medical intervention, they must be able to understand the decision and the information provided, retain that information, weigh up the pros and cons, and communicate their decision.

      Valid consent can only be provided by adults, either by the patient themselves, a person authorized under a Lasting Power of Attorney, or someone with the authority to make treatment decisions, such as a court-appointed deputy or a guardian with welfare powers.

      In the UK, patients aged 16 and over are assumed to have the capacity to consent. If a patient is under 18 and appears to lack capacity, parental consent may be accepted. However, a young person of any age may consent to treatment if they are considered competent to make the decision, known as Gillick competence. Parental consent may also be given by those with parental responsibility.

      The Fraser guidelines apply to the prescription of contraception to under 16’s without parental involvement. These guidelines allow doctors to provide contraceptive advice and treatment without parental consent if certain criteria are met, including the young person understanding the advice, being unable to be persuaded to inform their parents, and their best interests requiring them to receive contraceptive advice or treatment.

      Competent adults have the right to refuse consent, even if it is deemed unwise or likely to result in harm. However, there are exceptions to this, such as compulsory treatment authorized by the mental health act or if the patient is under 18 and refusing treatment would put their health at serious risk.

      In emergency situations where a patient is unable to give consent, treatment may be provided without consent if it is immediately necessary to save their life or prevent a serious deterioration of their condition. Any treatment decision made without consent must be in the patient’s best interests, and if a decision is time-critical and the patient is unlikely to regain capacity in time, a best interest decision should be made. The treatment provided should be the least restrictive on the patient’s future choices.

    • This question is part of the following fields:

      • Safeguarding & Psychosocial Emergencies
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  • Question 44 - A 42-year-old woman from Southeast Asia comes in with left-sided nasal blockage and...

    Incorrect

    • A 42-year-old woman from Southeast Asia comes in with left-sided nasal blockage and hearing difficulties in her left ear that have persisted for six weeks. She also reports experiencing postnasal drip. During the examination, a prominent palpable lymph node is found in the upper jugular chain on the left side.

      What is the SINGLE most probable diagnosis?

      Your Answer:

      Correct Answer: Nasopharyngeal carcinoma

      Explanation:

      This patient is experiencing a blockage in one nostril, hearing loss in one ear, and a newly developed hearing impairment. Additionally, there is a noticeable swollen lymph node in the upper jugular chain on the affected side. These symptoms strongly suggest the possibility of nasopharyngeal carcinoma.
      Nasopharyngeal carcinoma is not very common in the U.K., but it has a higher occurrence in individuals from Southeast Asia. In this region, the disease is often linked to the Epstein-Barr virus (EBV). It typically affects individuals between the ages of 40 and 70.
      The most common signs of nasopharyngeal carcinoma include a lump in the neck (present in approximately 80% of cases), one-sided nasal blockage (present in approximately 60% of cases), one-sided deafness (present in approximately 50% of cases), and post-nasal discharge (present in approximately 50% of cases). Lymph nodes in the upper jugular chain are often detectable.
      It is crucial to refer this patient urgently using a suspected cancer referral pathway to ensure an appointment within two weeks.
      For more information, please refer to the NICE guidelines on the recognition and referral of suspected cancer.

    • This question is part of the following fields:

      • Ear, Nose & Throat
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  • Question 45 - A 5-year-old child is brought into the emergency room by an ambulance with...

    Incorrect

    • A 5-year-old child is brought into the emergency room by an ambulance with sirens blaring. The child has been in a house fire and has sustained severe burns. The anesthesiologist examines the child's airway and is worried about the potential for airway blockage. Intubation is scheduled for the patient, and the necessary equipment is being prepared.
      As per the ATLS recommendations, what is the smallest internal diameter endotracheal tube that should be utilized?

      Your Answer:

      Correct Answer: 4.5 mm

      Explanation:

      Patients who have suffered burns should receive high-flow oxygen (15 L) through a reservoir bag while their breathing is being evaluated. If intubation is necessary, it is crucial to use an appropriately sized endotracheal tube (ETT). Using a tube that is too small can make it difficult or even impossible to ventilate the patient, clear secretions, or perform bronchoscopy.

      According to the ATLS guidelines, adults should be intubated using an ETT with an internal diameter (ID) of at least 7.5 mm or larger. Children, on the other hand, should have an ETT with an ID of at least 4.5 mm. Once a patient has been intubated, it is important to continue administering 100% oxygen until their carboxyhemoglobin levels drop to less than 5%.

      To protect the lungs, it is recommended to use lung protective ventilation techniques. This involves using low tidal volumes (4-8 mL/kg) and ensuring that peak inspiratory pressures do not exceed 30 cmH2O.

    • This question is part of the following fields:

      • Trauma
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  • Question 46 - You assess a patient who is currently undergoing systemic anticancer treatment. She has...

    Incorrect

    • You assess a patient who is currently undergoing systemic anticancer treatment. She has been experiencing chills and feeling unwell and is worried about the potential of having an infection. She informs you that she is currently prescribed a medication to prevent neutropenic sepsis.
      Which of the following medications is she most likely taking for this purpose?

      Your Answer:

      Correct Answer: Ciprofloxacin

      Explanation:

      According to the latest guidelines from NICE, it is recommended that adult patients who are undergoing treatment for acute leukaemia, stem cell transplants, or solid tumours and are expected to experience significant neutropenia as a result of chemotherapy, should be offered prophylaxis with a fluoroquinolone such as ciprofloxacin (500 mg taken orally twice daily) during the period when neutropenia is expected. This is to help prevent the occurrence of neutropenic sepsis, a serious infection that can occur in cancer patients with low levels of neutrophils.

      Reference:
      NICE guidance: ‘Neutropenic sepsis: prevention and management of neutropenic sepsis in cancer patients’

    • This question is part of the following fields:

      • Oncological Emergencies
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  • Question 47 - A 65 year old female is brought into the emergency department by her...

    Incorrect

    • A 65 year old female is brought into the emergency department by her husband following a fall. The patient seems unsure about how the fall occurred. The patient's husband takes you aside to express his growing concern about the patient's memory and overall functioning in the past year. He has previously suggested visiting the doctor about it, but the patient has consistently refused, claiming to be perfectly fine. The patient's husband is worried that the patient might be suffering from dementia. What is the leading cause of dementia?

      Your Answer:

      Correct Answer: Alzheimer's disease

      Explanation:

      Dementia is a condition characterized by a decline in cognitive abilities, such as memory, thinking, and reasoning, that is severe enough to interfere with daily functioning. There are several different causes of dementia, but the leading cause is Alzheimer’s disease. Alzheimer’s disease is a progressive brain disorder that affects memory, thinking, and behavior. It is the most common cause of dementia, accounting for approximately 60-80% of cases.

      Further Reading:

      Dementia is a progressive and irreversible clinical syndrome characterized by cognitive and behavioral symptoms. These symptoms include memory loss, impaired reasoning and communication, personality changes, and reduced ability to carry out daily activities. The decline in cognition affects multiple domains of intellectual functioning and is not solely due to normal aging.

      To diagnose dementia, a person must have impairment in at least two cognitive domains that significantly impact their daily activities. This impairment cannot be explained by delirium or other major psychiatric disorders. Early-onset dementia refers to dementia that develops before the age of 65.

      The most common cause of dementia is Alzheimer’s disease, accounting for 50-75% of cases. Other causes include vascular dementia, dementia with Lewy bodies, and frontotemporal dementia. Less common causes include Parkinson’s disease dementia, Huntington’s disease, prion disease, and metabolic and endocrine disorders.

      There are several risk factors for dementia, including age, mild cognitive impairment, genetic predisposition, excess alcohol intake, head injury, depression, learning difficulties, diabetes, obesity, hypertension, smoking, Parkinson’s disease, low social engagement, low physical activity, low educational attainment, hearing impairment, and air pollution.

      Assessment of dementia involves taking a history from the patient and ideally a family member or close friend. The person’s current level of cognition and functional capabilities should be compared to their baseline level. Physical examination, blood tests, and cognitive assessment tools can also aid in the diagnosis.

      Differential diagnosis for dementia includes normal age-related memory changes, mild cognitive impairment, depression, delirium, vitamin deficiencies, hypothyroidism, adverse drug effects, normal pressure hydrocephalus, and sensory deficits.

      Management of dementia involves a multi-disciplinary approach that includes non-pharmacological and pharmacological measures. Non-pharmacological interventions may include driving assessment, modifiable risk factor management, and non-pharmacological therapies to promote cognition and independence. Drug treatments for dementia should be initiated by specialists and may include acetylcholinesterase inhibitors, memantine, and antipsychotics in certain cases.

      In summary, dementia is a progressive and irreversible syndrome characterized by cognitive and behavioral symptoms. It has various causes and risk factors, and its management involves a multi-disciplinary approach.

    • This question is part of the following fields:

      • Neurology
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  • Question 48 - A 35-year-old woman comes in with amenorrhoea for the past six months following...

    Incorrect

    • A 35-year-old woman comes in with amenorrhoea for the past six months following childbirth. The delivery was complicated by a post-partum haemorrhage that necessitated a blood transfusion. She has been unable to produce breast milk or breastfeed. She has also mentioned a loss of hair in her underarm and pubic regions and a decreased sex drive.
      What is the SINGLE most probable diagnosis?

      Your Answer:

      Correct Answer: Sheehan’s syndrome

      Explanation:

      Sheehan’s syndrome is a condition where the pituitary gland becomes damaged due to insufficient blood flow and shock during and after childbirth, leading to hypopituitarism. The risk of developing this syndrome is higher in pregnancies with conditions that increase the chances of bleeding, such as placenta praevia and multiple pregnancies. Sheehan’s syndrome is quite rare, affecting only 1 in 10,000 pregnancies.

      During pregnancy, the anterior pituitary gland undergoes hypertrophy, making it more vulnerable to ischaemia in the later stages. While the posterior pituitary gland is usually unaffected due to its direct arterial supply, there have been rare cases where it is also involved.

      The clinical features of Sheehan’s syndrome include the absence or infrequency of menstrual periods, the inability to produce milk and breastfeed (galactorrhoea), decreased libido, fatigue and tiredness, and loss of pubic and axillary hair. Additionally, secondary hypothyroidism and adrenal insufficiency may also occur.

      Serum prolactin levels are typically low, measuring less than 5ng/ml. An MRI can be helpful in ruling out other pituitary issues, such as a pituitary tumor.

      The management of Sheehan’s syndrome involves hormone replacement therapy. With appropriate treatment, the prognosis for this condition is excellent.

    • This question is part of the following fields:

      • Obstetrics & Gynaecology
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  • Question 49 - A 10-year-old girl comes in with excessive thirst, frequent urination, and increased thirst....

    Incorrect

    • A 10-year-old girl comes in with excessive thirst, frequent urination, and increased thirst. She has been feeling very fatigued lately and has experienced significant weight loss. Blood tests show normal levels of urea and electrolytes, but her bicarbonate level is 18 mmol/l (reference range 22-26 mmol/l). A urine dipstick test reveals 2+ protein and 3+ ketones.

      What is the SINGLE most probable diagnosis?

      Your Answer:

      Correct Answer: Type 1 diabetes mellitus

      Explanation:

      This child is displaying a typical pattern of symptoms for type I diabetes mellitus. He has recently experienced increased urination, excessive thirst, weight loss, and fatigue. Blood tests have revealed metabolic acidosis, and the presence of ketones in his urine indicates the development of diabetic ketoacidosis.

    • This question is part of the following fields:

      • Endocrinology
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  • Question 50 - A 15 kg toddler presents with clinical signs of shock and 10% dehydration...

    Incorrect

    • A 15 kg toddler presents with clinical signs of shock and 10% dehydration as a result of gastroenteritis. A 20 ml/kg fluid bolus is given initially.
      How much fluid should be given over the next 24 hours following this?

      Your Answer:

      Correct Answer: 4100 ml

      Explanation:

      The intravascular volume of an infant is approximately 80 ml/kg, while in older children it is around 70 ml/kg. Dehydration itself does not lead to death, but shock can. Shock can occur when there is a loss of 20 ml/kg from the intravascular space, whereas clinical dehydration is only noticeable after total losses greater than 25 ml/kg.

      The table below summarizes the maintenance fluid requirements for well, normal children based on their body weight:

      Bodyweight:
      – First 10 kg: Daily fluid requirement of 100 ml/kg, hourly fluid requirement of 4 ml/kg
      – Second 10 kg: Daily fluid requirement of 50 ml/kg, hourly fluid requirement of 2 ml/kg
      – Subsequent kg: Daily fluid requirement of 20 ml/kg, hourly fluid requirement of 1 ml/kg

      In general, a child showing clinical signs of dehydration without shock is assumed to be 5% dehydrated. If shock is also present, it is assumed that the child is 10% dehydrated or more. 5% dehydration means the body has lost 5 g per 100 g body weight, which is equivalent to 50 ml/kg of fluid. Therefore, 10% dehydration implies a loss of 100 ml/kg of fluid.

      In this case, the child is in shock and should receive a 20 ml/kg fluid bolus. The initial volume of fluid to administer should be 20 x 25% ml = 500 ml.

      Following this, the child requires:
      – 100 ml/kg replacement for the 10% dehydration = 100 x 25 = 2500 ml
      – 1st 10 kg = 100 ml/kg for daily maintenance fluid = 100 x 10 = 1000 ml
      – 2nd 10kg = 50 ml/kg for daily maintenance fluid = 50 x 10 = 500 ml
      – Subsequent kg = 20 ml/kg for daily maintenance fluid = 20 x 5 = 100 ml

      The total fluid needed for rehydration and maintenance is 2500 + 1600 = 4100 ml over a 24-hour period.

      The clinical features of dehydration are summarized below:

      Dehydration (5%):
      – Appears ‘unwell’
      – Normal heart rate or tachycardia
      – Normal respiratory rate or tachypnea
      – Normal peripheral pulses
      – Normal or mildly prolonged

    • This question is part of the following fields:

      • Nephrology
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SESSION STATS - PERFORMANCE PER SPECIALTY

Infectious Diseases (2/2) 100%
Elderly Care / Frailty (0/2) 0%
Pharmacology & Poisoning (1/2) 50%
Surgical Emergencies (0/1) 0%
Neurology (0/3) 0%
Mental Health (0/3) 0%
Endocrinology (1/1) 100%
Gastroenterology & Hepatology (1/2) 50%
Pain & Sedation (1/1) 100%
Resus (1/1) 100%
Musculoskeletal (non-traumatic) (0/2) 0%
Sexual Health (1/1) 100%
Ear, Nose & Throat (1/1) 100%
Cardiology (1/1) 100%
Environmental Emergencies (1/1) 100%
Ophthalmology (1/1) 100%
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