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Question 1
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Among the patients listed below, which one would benefit the most from hospice care involvement?
Patients:
1. A 25-year-old with a broken leg
2. A 45-year-old with stage 2 breast cancer
3. An 80-year-old with end-stage Alzheimer's disease
4. A 60-year-old with a mild case of pneumoniaYour Answer: A 65-year-old woman with end-stage dementia
Explanation:Assessing Hospice Needs in Patients with Different Medical Conditions
End-of-life care is an important consideration for patients with certain medical conditions. Hospice care is recommended for patients with a life expectancy of less than six months and who are no longer seeking curative treatment. Patients with end-stage dementia, for example, have limited life expectancy and may require hospice care. On the other hand, patients with relapsing-remitting multiple sclerosis may have palliative care needs but do not require hospice admission. Similarly, patients with moderate chronic obstructive pulmonary disease may require palliative care but do not need hospice admission. In contrast, patients with locally advanced prostate cancer may require hospice care and have treatment options such as watchful waiting, external radiotherapy with hormone therapy, surgery, hormone therapy on its own, cryotherapy as part of a clinical trial, or high-frequency ultrasound therapy (HIFU) as part of a clinical trial. Understanding the hospice needs of patients with different medical conditions is crucial for providing appropriate end-of-life care.
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This question is part of the following fields:
- Palliative Care
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Question 2
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A 72-year-old retired teacher with advanced ovarian cancer is reviewed at home by her General Practitioner (GP). Her daughter requested a home visit due to significant deterioration in her health over the past few days, and she is concerned that she can no longer meet her healthcare needs at home without assistance.
During the consultation, the GP discusses considering hospice care for the patient.
To be appropriate for hospice care management, a patient must:Your Answer: No longer be seeking curative treatment
Explanation:Myths about Hospice Care: Debunked
Hospice care is often misunderstood, leading to misconceptions about who can receive it and what it entails. Here are some common myths about hospice care debunked:
Myth #1: Hospice care is only for patients with terminal cancer.
Fact: Patients with any terminal diagnosis can seek hospice care, not just those with cancer. Commonly, patients with chronic lung disease, dementia, and neurodegenerative disorders benefit from hospice care.Myth #2: Patients must be bed-bound to receive hospice care.
Fact: Mobility status does not affect admission to hospice. Patients in hospices often take part in activities and may be fully mobile.Myth #3: Patients must have a ‘do not resuscitate’ (DNACPR) decision to receive hospice care.
Fact: Although most patients will have a DNACPR decision in a hospice, this is not a requirement.Myth #4: Patients must have uncontrolled pain to receive hospice care.
Fact: While some patients may be admitted to a hospice for pain control, hospices are able to treat other symptoms, and pain control can be addressed in other settings, depending on the patient’s needs and wishes.Hospice care and palliative care both focus on quality of life care for the patient and address adjustment to illness and end-of-life issues. Both forms of care address pain and symptom control issues for patients. However, hospice care is for patients who are no longer actively seeking curative treatment and have a terminal diagnosis with a life expectancy of 6 months or less. In contrast, for palliative care treatment, patients may still be undergoing aggressive treatment and do not have to be terminally ill. It is important to understand the facts about hospice care to make informed decisions about end-of-life care.
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This question is part of the following fields:
- Palliative Care
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Question 3
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You are the out-of-hours General Practitioner (GP) on call. You receive a call from the relative of an 85-year-old woman with palliative breast cancer and a complete Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) order. The relative believes she has passed away and is not sure what to do. You offer your condolences and arrange a home visit to confirm death.
Which of the following should be confirmed in order to diagnose death?Your Answer: No response to verbal/painful stimuli, absence of carotid pulse, absence of breath sounds for more than three minutes, absence of heart sounds for more than two minutes, pupils fixed and dilated
Explanation:Assessing for Death: Signs and Symptoms
When diagnosing death, it is important to look for signs of life initially, including skin color, signs of respiratory effort, and response to verbal/painful stimuli. Painful stimuli can be assessed using various methods, such as fingernail bed pressure, supraorbital pressure, or trapezius squeeze. Pupils should be assessed using a pen torch, as they become fixed and dilated after death. A central pulse, such as the carotid pulse, should be palpated, and doctors should listen for heart sounds for at least two minutes and breath sounds for at least three minutes. Exact durations may vary, but a minimum of five minutes of auscultation should be conducted to confirm irreversible cardiorespiratory arrest.
However, assessing for a gag reflex is not a routine part of diagnosing death, and the absence of a gag reflex may not necessarily indicate death. Instead, the absence of a corneal reflex can be used to diagnose death.
It is important to note that one minute of auscultation for breath and heart sounds would be insufficient to diagnose death. Additionally, assessing for a peripheral pulse, such as the radial pulse, would not be accurate, as it can be lost in peripherally shut down or hypotensive patients. Confirmation of death requires the absence of a central pulse, such as the carotid pulse, and the absence of breath and heart sounds for an adequate amount of time, along with fixed and dilated pupils.
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This question is part of the following fields:
- Palliative Care
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Question 4
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A 57-year-old retired nurse is receiving palliative care for terminal metastatic lung cancer. Her pain has been well managed until recently, when she started experiencing discomfort about an hour before her next dose of pain medication. This is causing her to feel anxious and concerned about her ability to cope with the pain.
What are the advantages of treating pain during palliative care?Your Answer: All of the above
Explanation:The Importance of Pain Control in Palliative Care
Pain is a crucial aspect of palliative care management. It is a multifaceted symptom that can impact a patient’s mobility, appetite, sleep, and overall quality of life. Addressing pain may involve improving mobility, which can help patients get out of bed and move around more easily. Pain control is also associated with better appetite and sleep, as well as reducing anxiety and improving general quality of life. Therefore, pain control is an essential component of palliative care that can significantly enhance a patient’s well-being.
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This question is part of the following fields:
- Palliative Care
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Question 5
Incorrect
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A 38-year-old woman is visited by her GP at home. She is nearing the end of her life due to metastatic cervical cancer and is currently receiving diamorphine through a syringe driver. Her family is worried because she has been experiencing increasing confusion and severe pain over the past few days. Her recent blood tests, including FBC, LFT, calcium, and CRP, are all normal. However, her renal function has significantly declined since her last blood test two weeks ago. On examination, the GP notes that she has small pupils and normal respiratory rate and oxygen saturation. The patient wishes to remain at home for her care and end-of-life, and does not want to be hospitalized under any circumstances. What would be the most appropriate management plan?
Your Answer: Reduce the dose of diamorphine and add haloperidol to the syringe driver
Correct Answer: Stop the current syringe driver and prescribe alfentanil via syringe driver for her pain
Explanation:Different Approaches to Managing a Palliative Care Patient’s Symptoms
When managing a patient in palliative care, it is important to consider the best approach to managing their symptoms. Here are some different approaches and their potential outcomes:
1. Prescribe alfentanil via syringe driver for pain relief: This is a good option for patients with renal failure or opiate toxicity problems.
2. Advise the patient to take only paracetamol and NSAIDs for pain: This may not be effective for patients experiencing severe pain, and they may not be able to swallow safely.
3. Admit the patient to hospital: This may not be in line with the patient’s wishes to remain at home during the final stages of their life.
4. Continue the current regime and advise the family: This may not address the patient’s symptoms and could lead to unnecessary suffering.
5. Reduce the dose of diamorphine and add haloperidol to the syringe driver: This may not be effective if the patient’s symptoms are due to a reversible cause.
Overall, it is important to consider the patient’s individual needs and wishes when managing their symptoms in palliative care.
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This question is part of the following fields:
- Palliative Care
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Question 6
Incorrect
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A 67-year-old man on palliative chemotherapy for advanced lung cancer is brought to the Emergency Department by his wife as he has been feeling increasingly weak and lethargic over the past few days. His arterial blood gas results are below:
Investigation Result Normal range
pH 7.51 7.35–7.45
Partial pressure of oxygen (PaO2) 11.7 kPa > 11 kPa
Partial pressure of carbon dioxide (PaCO2) 5.5 kPa 4.7–6.0 kPa
Bicarbonate (HCO3−) 29 mEq/l 22–26 mEq/l
Base excess +3 -2 to +2
Which of the following is most likely to cause this result?Your Answer: Respiratory depression
Correct Answer: Vomiting
Explanation:Causes of Acid-Base Imbalances: Explanation and Examples
Vomiting: When a patient’s arterial blood gas shows an uncompensated metabolic alkalosis, it suggests an acute cause such as vomiting. Vomiting causes a loss of stomach acid, resulting in fewer H+ ions to bind to HCO3-, leading to more free HCO3- and resulting in a metabolic alkalosis.
Aspirin Overdose: An aspirin overdose typically causes an initial respiratory alkalosis followed by a metabolic acidosis with a raised anion gap. The respiratory alkalosis is the result of direct stimulation of the medulla, while the metabolic acidosis is caused by an accumulation of lactic acid due to an uncoupling of oxidative phosphorylation.
Anxiety: Hyperventilation associated with anxiety would cause a respiratory alkalosis. This is due to ‘blowing off’ carbon dioxide through hyperventilation, resulting in a decreased PaCO2 in the blood and an increased ratio of HCO3− to PaCO2, raising the pH and resulting in alkalosis.
Pulmonary Embolism: A pulmonary embolism would cause a respiratory alkalosis, usually accompanied by hypoxia or type I respiratory failure.
Respiratory Depression: Respiratory depression would cause a respiratory acidosis. Hypoventilation means that less carbon dioxide is blown off, resulting in an increase in PaCO2 in the blood, which decreases the pH.
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This question is part of the following fields:
- Palliative Care
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Question 7
Incorrect
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An 80-year-old nursing home resident with end-stage dementia has an acute bowel obstruction; she is not a suitable candidate for surgical intervention.
Which of the following medications may be most effective in reducing her discomfort?Your Answer: Lorazepam
Correct Answer: Loperamide hydrochloride
Explanation:Medications for Managing Bowel Obstruction in End-of-Life Care
Bowel obstruction during end-of-life care can be managed without surgery or nasogastric tube placement. Loperamide hydrochloride, an antidiarrhoeal medication, can provide relief by reducing bowel motility when used with an opiate analgesic. Ondansetron, an antiemetic, can treat nausea but may cause constipation by slowing gastric stasis. Dexamethasone can alleviate bowel discomfort by reducing inflammation and oedema caused by a tumour obstructing the bowel. Lorazepam can help alleviate distress or anxiety caused by symptoms, but it does not improve them. Paracetamol is a weak analgesic and is unlikely to relieve discomfort in this case.
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This question is part of the following fields:
- Palliative Care
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Question 8
Incorrect
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A 60-year-old man visits his GP with metastatic lung cancer. He reports taking 1 g of paracetamol four times daily and codeine 60 mg four times daily, but is still experiencing pain. What is the best course of action for managing his pain?
Your Answer: Stop codeine and start morphine sulphate modified release 60 mg twice daily with view to titrate dose
Correct Answer: Stop codeine and start morphine sulphate modified release 15 mg twice daily with view to titrate dose
Explanation:Choosing the Right Opioid for Inadequate Pain Control
Explanation:
When a patient has inadequate pain control on a weak opiate and non-opiate combination, it’s important to consider switching to a strong opiate. However, choosing the right opioid requires careful consideration of the patient’s needs and potential risks.
One option is to stop codeine and start morphine sulphate modified release at a low dose, with the intention of titrating the dose slowly to reduce the risk of overdose. Short-acting morphine can be used for breakthrough pain, and the dose of the modified release morphine can be adjusted as needed.
On the other hand, switching to co-codamol or dihydrocodeine may not provide sufficient pain relief for this patient. Co-codamol at the same dose as the current codeine regimen would not improve pain control, while dihydrocodeine may require higher doses than morphine.
Finally, tramadol is a weak opioid and may not be effective for this patient’s level of pain. Instead, starting with a low dose of morphine and titrating slowly may be the best option for achieving adequate pain control while minimizing the risk of adverse effects.
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This question is part of the following fields:
- Palliative Care
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Question 9
Incorrect
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A 75-year-old man comes to his GP for a medication review. He has metastatic bowel cancer and is in relatively good health, still able to move around and take care of himself. He has been eating and drinking well. Currently, he is taking modified release morphine sulphate tablets (MST) 20 mg twice daily and using oramorph 10 mg/5 ml for breakthrough pain 4-6 times a day. He has not reported any adverse effects.
What would be the best course of action for managing his medication?Your Answer: Continue current regime
Correct Answer: Increase the dose of modified release MST and advise him to reduce the frequency of oramorph if possible
Explanation:Options for Managing Inadequate Pain Relief in a Patient on Opiates
When a patient on opiates experiences inadequate pain relief, there are several options for managing their medication. One option is to increase the dose of modified release morphine sulphate tablets (MST) while advising the patient to reduce the frequency of breakthrough medication, such as oramorph. However, caution must be taken to avoid overdose, and the patient should be aware of the risks of continuing their current regime.
Another option is to switch to a different opiate, such as oxycodone, but this may not be necessary if the patient is tolerating the current medication well. In this case, the dose of MST can be titrated cautiously and reviewed regularly.
A fentanyl patch may also be an option, but only if the patient is unable to take tablets due to eating or drinking difficulties.
If the patient requires multiple doses of breakthrough medication, the BNF recommends reviewing the dose of longer-acting analgesia.
Ultimately, the best course of action will depend on the individual patient’s needs and condition, and a full review of their medication and pain management plan should be performed if necessary.
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This question is part of the following fields:
- Palliative Care
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Question 10
Incorrect
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During a Monday lunchtime home visit, you encounter a 72-year-old patient with metastatic colon cancer who has been experiencing a decline in health over the past 2 months. The patient has extensive disease with liver and peritoneal metastatic deposits and also suffers from type II diabetes mellitus and moderately severe chronic obstructive pulmonary disease (COPD). To manage her pain, she takes ibuprofen 400 mg three times daily (tid), paracetamol 1 g four times daily (qds), morphine sulfate modified-release tablets (MST) 30 mg twice daily (bd), and Oramorph® 10 mg as required (prn). However, her abdominal pain has worsened over the weekend, and she has required three doses of Oramorph® per day in addition to her other analgesia. Although the dose is effective, the pain returns after about 2-3 hours. The patient is able to consume small amounts of food and fluid but appears to be in poor health with jaundice and quick, shallow breathing. What is the most appropriate treatment for her pain?
Your Answer: Increase her MST dose to 45 mg bd, but leave her Oramorph® dose at 10 mg prn in view of co-morbidities
Correct Answer: Increase her MST dose to 45 mg bd and Oramorph® dose to 15 mg prn
Explanation:Managing Pain in a Palliative Care Patient: Dosage Adjustments and Adjuncts
When managing pain in a palliative care patient, it is important to consider the appropriate dosage adjustments and adjuncts to provide effective pain relief. In the given scenario, the patient was taking 60 mg of morphine (as MST) and required another 30 mg of Oramorph® per day for breakthrough pain, resulting in a total daily dose of 90 mg. To address uncontrolled pain, the MST dose was increased to 45 mg bd and the Oramorph® dose was adjusted to 15 mg prn, with the breakthrough dose being one-sixth of the total daily dose.
While dexamethasone may be considered as an adjunct for liver capsule pain, amitriptyline is not indicated for neuropathic pain in this case. Increasing the dose of ibuprofen is also unlikely to provide significant pain relief. Instead, it is advisable to stick to oral morphine and adjust the dosage accordingly.
In some cases, a continuous subcutaneous infusion of morphine sulfate may be necessary, but it is preferable to use the oral route when possible to reduce the risk of infection and improve patient comfort. Overall, careful consideration of dosage adjustments and adjuncts can help provide effective pain relief for palliative care patients.
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This question is part of the following fields:
- Palliative Care
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