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  • Question 1 - A 7-year-old is brought in by his father who is worried about his...

    Correct

    • A 7-year-old is brought in by his father who is worried about his son's right hip pain that has been ongoing for the past 7 weeks. The father reports that the pain has been getting worse and is now causing his son to wake up at night. Over the last week, he has noticed his son limping and having difficulty getting in and out of the car and bathtub.

      What is the probable diagnosis?

      Your Answer: Perthes' disease

      Explanation:

      Perthes disease is characterized by avascular necrosis of the femoral head, leading to progressive hip pain, stiffness, and limp. It typically affects children between the ages of 4-8 years and can take 2-3 years to heal. Slipped upper femoral epiphysis, which affects overweight or tall thin adolescents, and developmental dysplasia present differently. Transient synovitis of the hip, which resolves within 7-10 days, is not likely due to the absence of a preceding viral illness. Septic joint is also unlikely based on the given information.

      Understanding Perthes’ Disease

      Perthes’ disease is a degenerative condition that affects the hip joints of children, typically between the ages of 4-8 years. It is caused by a lack of blood supply to the femoral head, which leads to bone infarction and avascular necrosis. This condition is more common in boys, with around 10% of cases being bilateral. The symptoms of Perthes’ disease include hip pain, stiffness, reduced range of hip movement, and a limp. Early changes can be seen on an x-ray, such as widening of the joint space, while later changes include decreased femoral head size and flattening.

      To diagnose Perthes’ disease, a plain x-ray is usually sufficient. However, if symptoms persist and the x-ray is normal, a technetium bone scan or magnetic resonance imaging may be necessary. If left untreated, Perthes’ disease can lead to complications such as osteoarthritis and premature fusion of the growth plates.

      The severity of Perthes’ disease is classified using the Catterall staging system, which ranges from stage 1 (clinical and histological features only) to stage 4 (loss of acetabular integrity). Treatment options include keeping the femoral head within the acetabulum using a cast or braces, observation for children under 6 years old, and surgical management for older children with severe deformities. The prognosis for Perthes’ disease is generally good, with most cases resolving with conservative management. Early diagnosis is key to improving outcomes.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 2 - A newborn delivered at 36 weeks gestation through a normal vaginal delivery is...

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    • A newborn delivered at 36 weeks gestation through a normal vaginal delivery is exhibiting irritability and has experienced a convulsion 72 hours after birth. No visible head trauma or swelling is present. What type of cranial injury is most probable in this case?

      Your Answer: Intraventricular haemorrhage

      Explanation:

      Caput succedaneum is a condition that occurs when pressure is applied to the fetal scalp during birth, resulting in a swollen and bruised area. This condition typically resolves on its own within a few days and does not require treatment.

      Cephalohaematoma, on the other hand, can occur after a vaginal delivery or due to trauma from obstetric tools. This condition results in bleeding between the skull and the periosteum, causing a tense swelling that is limited to the outline of the bone. Cephalohaematoma typically resolves over a period of weeks to months.

      Subaponeurotic haemorrhage, also known as subgaleal haemorrhage, is a rare condition that can occur due to a traumatic birth. This condition can result in significant blood loss in the infant.

      Intracranial haemorrhage refers to bleeding within the brain, including subarachnoid, subdural, and intraventricular haemorrhages. Subarachnoid haemorrhages are common and can cause irritability and convulsions in the first few days of life. Subdural haemorrhages can occur due to the use of forceps during delivery. Intraventricular haemorrhages are most common in preterm infants and can be diagnosed using ultrasound examinations.

      Understanding Intraventricular Haemorrhage

      Intraventricular haemorrhage is a rare condition that involves bleeding into the ventricular system of the brain. While it is typically associated with severe head injuries in adults, it can occur spontaneously in premature neonates. In fact, the majority of cases occur within the first 72 hours after birth. The exact cause of this condition is not well understood, but it is believed to be a result of birth trauma and cellular hypoxia in the delicate neonatal central nervous system.

      Treatment for intraventricular haemorrhage is largely supportive, as therapies such as intraventricular thrombolysis and prophylactic cerebrospinal fluid drainage have not been shown to be effective. However, if hydrocephalus and rising intracranial pressure occur, shunting may be necessary. It is important for healthcare professionals to be aware of this condition and its potential complications in order to provide appropriate care for affected patients.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 3 - A 68-year-old man of African descent with a family history of cancer presented...

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    • A 68-year-old man of African descent with a family history of cancer presented with an elevated PSA level of 23 ng/ml and was diagnosed with adenocarcinoma with a Gleason score of 7. Magnetic resonance imaging revealed abnormal signals on both sides of the prostate, and a bone scan showed two bone metastatic lesions. The clinical stage was T2 N0 M1b, and he received surgical and hormonal treatment. Genetic testing was performed to determine the most likely mutation he has.

      What mutation is he most likely to have?

      Your Answer: BRCA mutation

      Explanation:

      Men who carry BRCA mutations are at a higher risk of developing prostate cancer, particularly those with the BRCA2 gene which is associated with a more aggressive form of the disease. BRCA1 and BRCA2 are tumor suppressor genes that are inherited in an autosomal dominant manner with incomplete penetrance. On the other hand, APC mutation is not a major contributor to the development of clinical prostate cancer, as it is primarily responsible for colorectal tumors, often accompanied by ras and p53 mutations. BRAF mutation is an incorrect answer, as it is rare in both early and late-stage prostate cancer, but is found in approximately 50% of melanomas.

      Understanding Tumour Suppressor Genes

      Tumour suppressor genes are responsible for controlling the cell cycle and preventing the development of cancer. When these genes lose their function, the risk of cancer increases. However, it is important to note that both alleles of the gene must be mutated before cancer can occur.

      There are several examples of tumour suppressor genes, including p53, APC, BRCA1 & BRCA2, NF1, Rb, WT1, and MTS-1 (p16). These genes are associated with various types of cancer, such as colorectal cancer, breast and ovarian cancer, neurofibromatosis, retinoblastoma, Wilm’s tumour, and melanoma.

      It is crucial to understand the role of tumour suppressor genes in preventing cancer and the consequences of their loss of function. In contrast to oncogenes, which result in an increased risk of cancer due to a gain of function, tumour suppressor genes must be both mutated before cancer can occur. By studying these genes and their functions, researchers can develop new strategies for cancer prevention and treatment.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 4 - A 3-year-old child is admitted with poor appetite. Over the last 24 hours,...

    Incorrect

    • A 3-year-old child is admitted with poor appetite. Over the last 24 hours, they have eaten only 25% of their usual amount and have had significantly fewer wet diapers than usual. The child has been particularly irritable over this time and is not settling. There is no past medical history, no known allergies, and there has been no travel outside of the UK.

      On examination, the child appears unsettled and grouchy. There are no rashes on exposure and the fontanelles appear normal. The physical observations reveal tachycardia and a fever of 39ºC. When you attempt to manually flex the child's neck you note that they also flex the hips and knees.

      What is the most appropriate empirical intravenous treatment for this child?

      Your Answer: Cefotaxime + amoxicillin

      Correct Answer: Ceftriaxone

      Explanation:

      Investigation and Management of Meningitis in Children

      Meningitis is a serious condition that can affect children. When investigating meningitis, it is important to note any contraindications to lumbar puncture, such as signs of raised intracranial pressure, focal neurological signs, papilloedema, significant bulging of the fontanelle, disseminated intravascular coagulation, or signs of cerebral herniation. For patients with meningococcal septicaemia, a lumbar puncture is contraindicated, and blood cultures and PCR for meningococcal should be obtained instead.

      The management of meningitis in children involves administering antibiotics, such as IV amoxicillin (or ampicillin) and IV cefotaxime for children under three months, and IV cefotaxime (or ceftriaxone) for children over three months. Steroids should be considered if the lumbar puncture reveals certain findings, such as purulent cerebrospinal fluid, a high white blood cell count, or bacteria on Gram stain. Fluids should be administered to treat shock, and cerebral monitoring should be conducted, including mechanical ventilation if necessary.

      It is also important to notify public health authorities and administer antibiotic prophylaxis to contacts. Ciprofloxacin is now preferred over rifampicin for this purpose. Overall, prompt and appropriate management of meningitis in children is crucial for ensuring the best possible outcomes.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 5 - A 16-year-old boy visits the GP with his father. His father is worried...

    Incorrect

    • A 16-year-old boy visits the GP with his father. His father is worried as he has noticed scars on his son's arms and after a lengthy conversation, his son has confessed to self-harming on multiple occasions. The GP has decided to refer the boy to CAMHS (Child and Adolescent Mental Health Services). What is the most appropriate approach to minimize the likelihood of future self-harm?

      Your Answer: Counselling

      Correct Answer: Cognitive behavioural therapy

      Explanation:

      Treatment Options for Self-Harm: Psychological Interventions and Care Plans

      Self-harm is a serious issue that requires appropriate treatment. While drug treatment is not recommended, psychological interventions such as cognitive behavioural therapy (CBT), psychodynamic therapy, and problem-solving therapy can be effective. It is important to offer sessions of a psychological intervention that are specifically structured for people who self-harm, while also tailoring the treatment plan to each individual. Family therapy is not recommended for this particular issue. Developing a care plan with agreed-upon aims for longer-term treatment is also crucial. Overall, a combination of psychological interventions and care plans can help reduce self-harm.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 6 - A 14-year-old girl presents to the emergency department with symptoms of a cold....

    Incorrect

    • A 14-year-old girl presents to the emergency department with symptoms of a cold. She has been experiencing a fever, runny nose, headache, and a dry cough for a few days. Despite taking paracetamol and ibuprofen, her temperature has not gone down, which worries her mother. The patient is alert, comfortable, and well-hydrated. During the examination, her temperature is 38.9ºC, heart rate is 110 bpm, blood pressure is 90/70 mmHg, and respiratory rate is 26 breaths per minute. Her chest is clear, throat is slightly red, and there are no signs of tonsillitis. Otoscopy shows no abnormalities, and her ears are non-tender. There are no rashes, photophobia, or neck stiffness. What is the appropriate management for this patient?

      Your Answer: Advise that this is likely viral, safety-net on importance of hydration and send home with antipyretics

      Correct Answer: Initiate sepsis six protocol

      Explanation:

      Children over the age of 12 have vital signs similar to adults. However, if a child presents with symptoms of sepsis, such as a high temperature, elevated heart rate, low blood pressure, and increased respiratory rate, it is important to initiate the sepsis six protocol and conduct further investigations to determine the source of infection. In such cases, it is not appropriate to send the child home or administer additional doses of antipyretics. Aspirin should not be given to children due to the risk of Reye’s syndrome. Broad-spectrum IV antibiotics should be administered if there is a suspected bacterial infection causing sepsis.

      Age-appropriate Vital Signs for Children

      Paediatric vital signs vary depending on the age of the child. The table below provides age-appropriate ranges for heart rate and respiratory rate. For children under one year old, a heart rate of 110-160 beats per minute and a respiratory rate of 30-40 breaths per minute is considered normal. For children between the ages of one and two, a heart rate of 100-150 beats per minute and a respiratory rate of 25-35 breaths per minute is normal. Children between the ages of two and five should have a heart rate of 90-140 beats per minute and a respiratory rate of 25-30 breaths per minute. For children between the ages of five and twelve, a heart rate of 80-120 beats per minute and a respiratory rate of 20-25 breaths per minute is normal. Finally, for children over the age of twelve, a heart rate of 60-100 beats per minute and a respiratory rate of 15-20 breaths per minute is considered normal. It is important for healthcare professionals to be aware of these age-appropriate vital sign ranges in order to properly assess the health of children.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 7 - A 14-year-old boy comes to the doctor's office with his mother. His father...

    Incorrect

    • A 14-year-old boy comes to the doctor's office with his mother. His father passed away two weeks ago. He is feeling very emotional and is hesitant to return to school. He has no known risk factors for depression.
      What is the most suitable course of action for managing his situation?

      Your Answer: Refer urgently to CAMHS

      Correct Answer: Supportive chat, provide resources and arrange follow-up

      Explanation:

      Managing Traumatic Life Events in Children: Appropriate Interventions and Referrals

      When a child experiences a traumatic life event, it is important to provide appropriate interventions and referrals to prevent the development of depression. For children with low risk of developing depression, a supportive chat, resource provision, and follow-up should be the first line of management. Urgent referral to Child and Adolescent Mental Health Services (CAMHS) is only necessary if the child has two or more risk factors for depression or is currently displaying signs of depression.

      Encouraging the child to return to school as soon as possible is also crucial. The school can offer support and help the child maintain contact with peers. Referral to CAMHS should only be considered if the child meets the criteria mentioned above.

      Initiating antidepressant medication such as fluoxetine should be done in secondary care and is not recommended for this child at present. By following appropriate interventions and referrals, we can help children cope with traumatic life events and prevent the development of depression.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 8 - A 9-year-old patient comes in with a history of increasing polyuria and polydipsia...

    Incorrect

    • A 9-year-old patient comes in with a history of increasing polyuria and polydipsia over the past eight months, along with diffuse bone pain. During the examination, the patient displays exophthalmos, seborrhoeic dermatitis, and indications of mastoiditis. What is the probable diagnosis?

      Your Answer: Graves' disease

      Correct Answer: Langerhans cell histiocytosis

      Explanation:

      Langerhans Cell Histiocytosis: A Rare Disorder with Unknown Cause

      Langerhans cell histiocytosis is a rare disorder that is characterized by the abnormal proliferation of histiocytes, resulting in the development of granulomatous lesions in various organs. The cause of this condition is unknown, and it can range in severity. One of the symptoms of Langerhans cell histiocytosis is bone pain, which can be accompanied by features of skull involvement. In some cases, patients with this disorder may also have diabetes insipidus.

      Langerhans cell histiocytosis is a complex condition that can be difficult to diagnose. However, if left untreated, it can lead to serious complications. Therefore, it is important for patients with symptoms of this disorder to seek medical attention as soon as possible. Treatment options may include chemotherapy, radiation therapy, and surgery, depending on the severity of the condition and the organs affected. With proper treatment, many patients with Langerhans cell histiocytosis are able to manage their symptoms and lead normal, healthy lives.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 9 - A 2-year-old child is brought to the emergency department by his parents. The...

    Correct

    • A 2-year-old child is brought to the emergency department by his parents. The parents have noticed that he is clutching his stomach. He has not eaten or drank any fluids for the entire day and he has vomited twice. His mother states the vomit was green in colour.

      The doctor suspects a diagnosis of intestinal malrotation due to the child's symptoms and orders an abdominal ultrasound. The ultrasound shows a whirlpool sign, confirming the diagnosis. On examination, the child appears distressed and has a distended abdomen with absent bowel sounds. He looks unwell.

      What is the appropriate management for this patient?

      Your Answer: Ladd's procedure

      Explanation:

      The appropriate treatment for a pediatric patient with intestinal malrotation and volvulus is Ladd’s procedure, which involves the division of Ladd bands and widening of the base of the mesentery. Malrotation occurs when the midgut does not complete its rotation during development, resulting in the cecum being fixed in the right upper quadrant by peritoneal bands known as Ladd bands. This can lead to the formation of a volvulus, which requires untwisting and removal of the Ladd bands, as well as resection of any necrotic bowel and removal of the appendix. The Kasai procedure is used for biliary atresia, Ramstedt pyloromyotomy for pyloric stenosis, and rectal washouts for Hirschsprung’s disease.

      Paediatric Gastrointestinal Disorders

      Pyloric stenosis is more common in males and has a 5-10% chance of being inherited from parents. Symptoms include projectile vomiting at 4-6 weeks of life, and diagnosis is made through a test feed or ultrasound. Treatment involves a Ramstedt pyloromyotomy, either open or laparoscopic.

      Acute appendicitis is uncommon in children under 3 years old, but when it does occur, it may present atypically. Mesenteric adenitis causes central abdominal pain and URTI, and is treated conservatively.

      Intussusception occurs in infants aged 6-9 months and causes colicky pain, diarrhea, vomiting, a sausage-shaped mass, and red jelly stool. Treatment involves reduction with air insufflation.

      Intestinal malrotation is characterized by a high caecum at the midline and may be complicated by the development of volvulus. Diagnosis is made through an upper GI contrast study and ultrasound, and treatment involves laparotomy or a Ladd’s procedure.

      Hirschsprung’s disease occurs in 1/5000 births and is characterized by delayed passage of meconium and abdominal distension. Treatment involves rectal washouts and an anorectal pull through procedure.

      Oesophageal atresia is associated with tracheo-oesophageal fistula and polyhydramnios, and may present with choking and cyanotic spells following aspiration. Meconium ileus is usually associated with cystic fibrosis and requires surgery to remove plugs. Biliary atresia causes jaundice and increased conjugated bilirubin, and requires an urgent Kasai procedure. Necrotising enterocolitis is more common in premature infants and is treated with total gut rest and TPN, with laparotomy required for perforations.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 10 - A 14-year-old girl is brought to the Emergency Department by her parents due...

    Correct

    • A 14-year-old girl is brought to the Emergency Department by her parents due to experiencing left-sided hip pain over the past few days. Upon examination, X-rays reveal a slipped upper femoral epiphysis (SUFE). What is the definitive treatment for this condition?

      Your Answer: Internal fixation across the growth plate

      Explanation:

      When a slipped upper femoral epiphysis (SCFE) occurs, it is crucial to seek immediate medical attention as there is a risk of avascular necrosis of the femoral head. Referral to paediatric orthopaedics is necessary, and the child should not bear weight and should be given pain relief to ensure comfort. The most effective treatment for SCFE is internal fixation surgery, which prevents the slip from worsening. The Ponseti method, which involves a series of manipulations and casts over several weeks, is typically used to treat clubfoot.

      Slipped Capital Femoral Epiphysis: A Rare Hip Condition in Children

      Slipped capital femoral epiphysis, also known as slipped upper femoral epiphysis, is a rare hip condition that primarily affects children between the ages of 10 and 15. It is more commonly seen in obese boys. This condition is characterized by the displacement of the femoral head epiphysis postero-inferiorly, which may present acutely following trauma or with chronic, persistent symptoms.

      The most common symptoms of slipped capital femoral epiphysis include hip, groin, medial thigh, or knee pain and loss of internal rotation of the leg in flexion. In some cases, a bilateral slip may occur. Diagnostic imaging, such as AP and lateral (typically frog-leg) views, can confirm the diagnosis.

      The management of slipped capital femoral epiphysis typically involves internal fixation, which involves placing a single cannulated screw in the center of the epiphysis. However, if left untreated, this condition can lead to complications such as osteoarthritis, avascular necrosis of the femoral head, chondrolysis, and leg length discrepancy.

      In summary, slipped capital femoral epiphysis is a rare hip condition that primarily affects children, especially obese boys. It is characterized by the displacement of the femoral head epiphysis postero-inferiorly and can present with various symptoms. Early diagnosis and management are crucial to prevent complications.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 11 - A 12-year-old boy is presented by his father with a widespread skin rash....

    Correct

    • A 12-year-old boy is presented by his father with a widespread skin rash. The boy has been experiencing itching for the past 3 days and has developed a fever along with the rash. During the examination, it is observed that the rash consists of macules, papules, crusted lesions, and vesicles that have spread across most of his body. The father has been administering ibuprofen to the boy for relief from fever and discomfort.
      What is the probable diagnosis, and why is ibuprofen not recommended in this case?

      Your Answer: The increased risk of necrotising fasciitis

      Explanation:

      The symptoms exhibited by this patient are consistent with chickenpox, including lesions at various stages of healing, fever, and itching. However, it is important to note that the use of NSAIDs can increase the risk of necrotising fasciitis in chickenpox patients. While ibuprofen is a suitable NSAID for patients of all ages, it is important to avoid aspirin due to the risk of Reye’s syndrome in children with chickenpox. Short-term use of ibuprofen during acute febrile illnesses is unlikely to cause significant gastrointestinal side effects.

      Chickenpox: Causes, Symptoms, and Management

      Chickenpox is a viral infection caused by the varicella zoster virus. It is highly contagious and can be spread through respiratory droplets. The virus can also reactivate later in life, causing shingles. Chickenpox is most infectious four days before the rash appears and until five days after the rash first appears. The incubation period is typically 10-21 days. Symptoms include fever, an itchy rash that starts on the head and trunk before spreading, and mild systemic upset.

      Management of chickenpox is supportive and includes keeping cool, trimming nails, and using calamine lotion. School exclusion is recommended during the infectious period. Immunocompromised patients and newborns with peripartum exposure should receive varicella zoster immunoglobulin (VZIG). If chickenpox develops, IV acyclovir may be considered. Secondary bacterial infection of the lesions is a common complication, which may be increased by the use of NSAIDs. In rare cases, invasive group A streptococcal soft tissue infections may occur, resulting in necrotizing fasciitis. Other rare complications include pneumonia, encephalitis, disseminated haemorrhagic chickenpox, arthritis, nephritis, and pancreatitis.

      Radiographic Findings in Varicella Pneumonia

      Varicella pneumonia is a rare complication of chickenpox that can occur in immunocompromised patients or adults. Radiographic findings of healed varicella pneumonia may include miliary opacities throughout both lungs, which are of uniform size and dense, suggesting calcification. There is typically no focal lung parenchymal mass or cavitating lesion seen. These findings are characteristic of healed varicella pneumonia.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 12 - Which one of the following is not included in the Apgar score for...

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    • Which one of the following is not included in the Apgar score for evaluating a neonate?

      Your Answer: Capillary refill time

      Explanation:

      The Apgar score is a tool used to evaluate the health of a newborn baby. It is recommended by NICE to be assessed at 1 and 5 minutes after birth, and again at 10 minutes if the initial score is low. The score is based on five factors: pulse, respiratory effort, color, muscle tone, and reflex irritability. A score of 0-3 is considered very low, 4-6 is moderate low, and 7-10 indicates that the baby is in good health. The score helps healthcare professionals quickly identify any potential issues and provide appropriate care.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 13 - Which feature is not typical of physiological jaundice? ...

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    • Which feature is not typical of physiological jaundice?

      Your Answer: Associated anaemia

      Explanation:

      Physiological Jaundice in Infants

      Physiological jaundice is a common occurrence in newborns, affecting around 90% of infants. It typically appears after the first two to three days of life and is caused by an increase in the breakdown of red blood cells and the relative immaturity of the liver. This type of jaundice is not usually a cause for concern and will often resolve on its own within a few weeks. However, if anemia is present, it may indicate a more serious underlying condition, such as hemolytic anemia. It is important for healthcare providers to monitor newborns for signs of jaundice and to investigate any potential underlying causes.

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      • Paediatrics
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  • Question 14 - A 6-week-old baby girl is brought to her pediatrician's office by her mother...

    Correct

    • A 6-week-old baby girl is brought to her pediatrician's office by her mother who is worried about her poor feeding over the past 24 hours. The mother has noticed that the baby feels warm but has not observed any signs of cough or cold. The baby is scheduled to receive her vaccinations next week. She has had a wet and dirty diaper today and her urine has a strong odor.

      During the examination, the baby has a fever of 38.9ºC and is fussy, but her chest and abdomen appear normal.

      What is the most appropriate course of action for this infant?

      Your Answer: Admit same day to the paediatrics ward for assessment

      Explanation:

      If a child under 3 months old is suspected to have a UTI, it is important to refer them to specialist paediatrics services. In the case of a baby with a persistent fever and no clear source of infection, a urine sample should be collected to check for a UTI. It is important to note that a raised temperature alone is considered a red sign according to NICE guidance for assessing fever in children, and the child should be referred for urgent paediatric assessment. It would be inappropriate to reassure the mother that this is just a virus and can be managed at home, and using paracetamol to manage the fever would not be acceptable in this case. While antibiotics may treat the infection, waiting a week for a review could be dangerous for an unwell child who may deteriorate rapidly. Referring the child for a routine review with paediatrics would also not be appropriate, as urgent attention is required. While a health visitor may be helpful for feeding issues, the short history of poor feeding and fever suggests that the baby is struggling to feed due to illness, and this would not address the current presentation.

      Urinary tract infections (UTI) are more common in boys until 3 months of age, after which the incidence is substantially higher in girls. Presentation in childhood depends on age, with infants showing poor feeding, vomiting, and irritability, younger children showing abdominal pain, fever, and dysuria, and older children showing dysuria, frequency, and haematuria. NICE guidelines recommend checking urine samples in children with symptoms or signs suggestive of a UTI, unexplained fever of 38°C or higher, or an alternative site of infection but who remain unwell. Urine collection should be done through clean catch or urine collection pads, and invasive methods should only be used if non-invasive methods are not possible. Management includes referral to a paediatrician for infants less than 3 months old, admission to hospital for children aged more than 3 months old with an upper UTI, and oral antibiotics for 3-10 days for children aged more than 3 months old with a lower UTI. Antibiotic prophylaxis is not given after the first UTI but should be considered with recurrent UTIs.

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      • Paediatrics
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  • Question 15 - A 6-week-old baby girl starts to experience forceful vomiting after every feeding. She...

    Correct

    • A 6-week-old baby girl starts to experience forceful vomiting after every feeding. She had been gaining weight normally prior to this. What is the probable diagnosis?

      Your Answer: Pyloric stenosis

      Explanation:

      There are several medical conditions that can affect newborns and infants, including pyloric stenosis, congenital duodenal atresia, Hirschsprung’s disease, tracheoesophageal fistula (TOF), and necrotising enterocolitis (NEC). Pyloric stenosis is a condition where the circular pyloric muscle becomes hypertrophied, leading to non-bilious, projectile vomiting and constipation. Congenital duodenal atresia is the absence or closure of a portion of the lumen of the duodenum, causing bile-stained vomiting, abdominal distension, and inability to pass meconium. Hirschsprung’s disease is a congenital defect where ganglion cells fail to migrate into the hindgut, leading to functional intestinal obstruction and failure to pass meconium. TOF is a communication between the trachea and oesophagus, usually associated with oesophageal atresia, causing choking, coughing, and cyanosis during feeding. NEC is a condition primarily seen in premature infants, where portions of the bowel undergo necrosis, causing bilious vomiting, distended abdomen, and bloody stools. It is important to recognize the symptoms of these conditions early on to ensure prompt treatment and prevent complications.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 16 - A 4-year-old girl, Lily, is taken to the pediatrician by her father. He...

    Correct

    • A 4-year-old girl, Lily, is taken to the pediatrician by her father. He is concerned about an umbilical hernia that Lily has had since birth. He was told that it would likely go away on its own, but it has not yet resolved. The pediatrician conducts an examination and finds a 1.5 cm umbilical hernia that is easily reducible. What is the most suitable course of action for managing this, according to the guidelines?

      Your Answer: Delaying referral for elective outpatient surgical repair until 5 years of age, if still unresolved

      Explanation:

      According to medical guidelines, umbilical hernias in children usually close on their own by the age of 4-5. However, if the hernia persists beyond this age or is large and causing symptoms, surgical repair is recommended. In the case of a small hernia in a 3-year-old child, observation is appropriate until the age of 5. If the hernia becomes incarcerated, it should be manually reduced and surgically repaired within 24 hours. The use of compression therapy after surgery is not recommended. Waiting for the hernia to self-resolve after the age of 5 is not advised as it is unlikely to happen and could lead to incarceration. These recommendations are based on BMJ Best Practice guidelines.

      Umbilical Hernia in Children: Causes and Treatment

      Umbilical hernias are a common occurrence in children and are often detected during the newborn examination. This condition is characterized by a bulge or protrusion near the belly button, caused by a weakness in the abdominal muscles. While umbilical hernias can occur in any child, they are more common in Afro-Caribbean infants and those with Down’s syndrome or mucopolysaccharide storage diseases.

      Fortunately, in most cases, umbilical hernias in children do not require treatment and will resolve on their own by the age of three. However, if the hernia persists beyond this age or becomes painful, surgery may be necessary to repair the abdominal wall. It is important to monitor the hernia and seek medical attention if there are any changes in size or symptoms.

      In summary, umbilical hernias are a common condition in children that typically resolve on their own without treatment. However, certain factors such as ethnicity and underlying medical conditions may increase the likelihood of developing an umbilical hernia. Parents should be aware of the signs and symptoms of umbilical hernias and seek medical attention if necessary.

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      • Paediatrics
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  • Question 17 - A 5-year-old boy comes to the clinic with a history of diarrhoea lasting...

    Correct

    • A 5-year-old boy comes to the clinic with a history of diarrhoea lasting for 2 weeks. Upon examination, he is found to be dehydrated. Further investigations reveal hypernatraemia. What signs are most likely to be observed during the physical examination?

      Your Answer: Jittery movements

      Explanation:

      Signs indicating hypernatraemic dehydration include tremulous movements, heightened muscle tension, exaggerated reflexes, seizures, and lethargy or unconsciousness.

      Managing Diarrhoea and Vomiting in Children

      Diarrhoea and vomiting are common in young children, with rotavirus being the most common cause of gastroenteritis in the UK. According to the 2009 NICE guidelines, diarrhoea usually lasts for 5-7 days and stops within 2 weeks, while vomiting usually lasts for 1-2 days and stops within 3 days. When assessing hydration status, NICE recommends using normal, dehydrated, or shocked categories instead of the traditional mild, moderate, or severe categories.

      Children younger than 1 year, especially those younger than 6 months, infants who were of low birth weight, and those who have passed six or more diarrhoeal stools in the past 24 hours or vomited three times or more in the past 24 hours are at an increased risk of dehydration. Additionally, children who have not been offered or have not been able to tolerate supplementary fluids before presentation, infants who have stopped breastfeeding during the illness, and those with signs of malnutrition are also at risk.

      If clinical shock is suspected, children should be admitted for intravenous rehydration. For children without evidence of dehydration, it is recommended to continue breastfeeding and other milk feeds, encourage fluid intake, and discourage fruit juices and carbonated drinks. If dehydration is suspected, give 50 ml/kg low osmolarity oral rehydration solution (ORS) solution over 4 hours, plus ORS solution for maintenance, often and in small amounts. It is also important to continue breastfeeding and consider supplementing with usual fluids, including milk feeds or water, but not fruit juices or carbonated drinks.

      In terms of diagnosis, NICE suggests doing a stool culture in certain situations, such as when septicaemia is suspected, there is blood and/or mucous in the stool, or the child is immunocompromised. A stool culture should also be considered if the child has recently been abroad, the diarrhoea has not improved by day 7, or there is uncertainty about the diagnosis of gastroenteritis. Features suggestive of hypernatraemic dehydration include jittery movements, increased muscle tone, hyperreflexia, convulsions, and drowsiness or coma.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 18 - A 7-week old infant has been admitted to the hospital due to concerns...

    Correct

    • A 7-week old infant has been admitted to the hospital due to concerns from her father about her inability to keep down feeds. The father reports that shortly after being fed, the baby forcefully vomits up uncurdled milk. He is anxious because the baby does not seem to be gaining weight. Based on the probable diagnosis, what metabolic irregularity is the patient expected to exhibit?

      Your Answer: Hypochloremic hypokalemic metabolic alkalosis

      Explanation:

      Pyloric stenosis is the probable diagnosis when a newborn experiences non-bilious vomiting during the first few weeks of life. This condition results in the loss of hydrochloric acid (HCl) from the stomach contents, leading to hypochloremia and potassium loss. The metabolic alkalosis is caused by the depletion of hydrogen ions due to the vomiting of stomach acid.

      Understanding Pyloric Stenosis

      Pyloric stenosis is a condition that usually occurs in infants between the second and fourth weeks of life. However, in rare cases, it may present later, up to four months. This condition is caused by the thickening of the circular muscles of the pylorus. Pyloric stenosis is more common in males, with an incidence of 4 per 1,000 live births. It is also more likely to affect first-borns and infants with a positive family history.

      The most common symptom of pyloric stenosis is projectile vomiting, which usually occurs about 30 minutes after a feed. Other symptoms may include constipation, dehydration, and a palpable mass in the upper abdomen. Prolonged vomiting can lead to hypochloraemic, hypokalaemic alkalosis, which can be life-threatening.

      Diagnosis of pyloric stenosis is typically made using ultrasound. Management of this condition involves a surgical procedure called Ramstedt pyloromyotomy. This procedure involves making a small incision in the pylorus to relieve the obstruction and allow for normal passage of food. With prompt diagnosis and treatment, infants with pyloric stenosis can make a full recovery.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 19 - A 7-year-old child is brought to the GP practice for an urgent appointment...

    Incorrect

    • A 7-year-old child is brought to the GP practice for an urgent appointment by their parent. They have a 7 day history of fever and dry cough but in the last 24hrs their parent has become increasingly concerned about their breathing. They also report the child is refusing food and has had very few wet nappies.
      The child's observations are oxygen saturation 93% on air, respiratory rate 58 breaths/min, heart rate 160 bpm, blood pressure 85/45 mmHg and temperature 38.1ºC.
      On examination, the child's breathing appears rapid with marked intercostal recession and use of accessory muscles. They are also making a grunting noise.
      Which of these findings would indicate immediate referral to hospital by ambulance?

      Your Answer: Heart rate 160 bpm

      Correct Answer: Grunting

      Explanation:

      Immediate admission would be necessary for a heart rate of 200bpm. A heart rate of 160 bpm would be worrisome and hospital evaluation should be contemplated, but the urgency would vary based on the patient’s clinical state.

      Bronchiolitis is a condition where the bronchioles become inflamed, and it is most commonly caused by respiratory syncytial virus (RSV). This virus is responsible for 75-80% of cases, with other causes including mycoplasma and adenoviruses. Bronchiolitis is most prevalent in infants under one year old, with 90% of cases occurring in those aged 1-9 months. The condition is more serious in premature babies, those with congenital heart disease or cystic fibrosis. Symptoms include coryzal symptoms, dry cough, increasing breathlessness, and wheezing. Hospital admission is often necessary due to feeding difficulties associated with increasing dyspnoea.

      Immediate referral is recommended if the child has apnoea, looks seriously unwell, has severe respiratory distress, central cyanosis, or persistent oxygen saturation of less than 92% when breathing air. Clinicians should consider referral if the child has a respiratory rate of over 60 breaths/minute, difficulty with breastfeeding or inadequate oral fluid intake, or clinical dehydration. Immunofluorescence of nasopharyngeal secretions may show RSV, and management is largely supportive. Humidified oxygen is given via a head box if oxygen saturations are persistently low, and nasogastric feeding may be necessary if children cannot take enough fluid/feed by mouth. Suction may also be used for excessive upper airway secretions. NICE released guidelines on bronchiolitis in 2015 for more information.

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      • Paediatrics
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  • Question 20 - A mother brings her 12-year-old boy into the Emergency Department. She is concerned...

    Correct

    • A mother brings her 12-year-old boy into the Emergency Department. She is concerned as he has started to limp over the last few days and is in pain. There is no history of trauma; he has no temperature and is otherwise well. You notice he is overweight for his age.
      Which is the most likely diagnosis?

      Your Answer: Slipped femoral epiphysis

      Explanation:

      Pediatric Hip Conditions: Slipped Femoral Epiphysis, Perthes’ Disease, Septic Arthritis, and Juvenile Idiopathic Arthritis

      Hip conditions in children can present with a variety of symptoms and causes. One common condition is slipped femoral epiphysis, which typically affects boys aged 10-16 who are overweight. Symptoms include a painful limp, limited internal rotation, and displacement of the femoral head on X-ray. Treatment involves surgical fixation.

      Another condition is Perthes’ disease, which is avascular necrosis of the femoral head and typically affects younger children aged 4-10, more commonly in boys. Symptoms include an intermittent limp and limited joint movement. Treatment can be medical or surgical, but surgery may result in limb shortening and a permanent limp.

      Septic arthritis presents with an acutely painful, inflamed, and swollen joint, often with fever. It is more common in patients with underlying joint disease or a history of trauma. Musculoskeletal back pain is unlikely in this scenario.

      Juvenile idiopathic arthritis is an autoimmune inflammatory joint disease seen in children under 16. It presents with joint swelling, morning pain, limping, lethargy, reduced activity, and poor appetite, and is associated with anterior uveitis and spiking fevers. However, it is unlikely in this scenario due to the chronicity of symptoms and the child’s overall health.

      In conclusion, pediatric hip conditions can have various causes and symptoms, and proper diagnosis and treatment are crucial for optimal outcomes.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 21 - A 2-month-old baby is brought to the GP clinic by their parent for...

    Correct

    • A 2-month-old baby is brought to the GP clinic by their parent for their first round of vaccinations. What vaccinations are recommended for this visit?

      Your Answer: 6-1 vaccine' (diphtheria, tetanus, whooping cough, polio, Hib and hepatitis B), one dose Men B (vaccine for group B meningococcal disease) and one dose of Rotavirus vaccine

      Explanation:

      The recommended vaccination schedule includes the 6-in-1 vaccine for diphtheria, tetanus, whooping cough, polio, Hib, and hepatitis B, as well as one dose each of the MMR vaccine for measles, mumps, and rubella, and the Rotavirus vaccine.

      The UK immunisation schedule recommends certain vaccines at different ages. At birth, the BCG vaccine is given if the baby is at risk of tuberculosis. At 2, 3, and 4 months, the ‘6-1 vaccine’ (diphtheria, tetanus, whooping cough, polio, Hib and hepatitis B) and oral rotavirus vaccine are given, along with Men B and PCV at certain intervals. At 12-13 months, the Hib/Men C, MMR, and PCV vaccines are given, along with Men B. At 3-4 years, the ‘4-in-1 preschool booster’ (diphtheria, tetanus, whooping cough and polio) and MMR vaccines are given. At 12-13 years, the HPV vaccination is given, and at 13-18 years, the ‘3-in-1 teenage booster’ (tetanus, diphtheria and polio) and Men ACWY vaccines are given. Additionally, the flu vaccine is recommended annually for children aged 2-8 years.

      It is important to note that the meningitis ACWY vaccine has replaced meningitis C for 13-18 year-olds due to an increased incidence of meningitis W disease in recent years. The ACWY vaccine will also be offered to new students (up to the age of 25 years) at university. GP practices will automatically send letters inviting 17-and 18-year-olds in school year 13 to have the Men ACWY vaccine. Students going to university or college for the first time as freshers, including overseas and mature students up to the age of 25, should contact their GP to have the Men ACWY vaccine, ideally before the start of the academic year.

      It is worth noting that the Men C vaccine used to be given at 3 months but has now been discontinued. This is because the success of the Men C vaccination programme means there are almost no cases of Men C disease in babies or young children in the UK any longer. All children will continue to be offered the Hib/Men C vaccine at one year of age, and the Men ACWY vaccine at 14 years of age to provide protection across all age groups.

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      • Paediatrics
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  • Question 22 - A 5 month old baby boy is brought to the Emergency Department by...

    Correct

    • A 5 month old baby boy is brought to the Emergency Department by his parents after they found him unresponsive. The baby was healthy prior to this incident. Despite advanced life support efforts, the baby could not be revived. His temperature upon arrival was 37.2ºC. The child had received all of his vaccinations and was up-to-date. During the post-mortem examination, bilateral retinal hemorrhages were discovered. What is the most probable cause of the baby's death?

      Your Answer: Aggressive shaking of the baby

      Explanation:

      Understanding Shaken Baby Syndrome

      Shaken baby syndrome is a condition that involves a combination of retinal haemorrhages, subdural haematoma, and encephalopathy. It occurs when a child between the ages of 0-5 years old is intentionally shaken. However, there is controversy among physicians regarding the mechanism of injury, making it difficult for courts to convict suspects of causing shaken baby syndrome to a child. This condition has made headlines due to the ongoing debate among medical professionals.

      Shaken baby syndrome is a serious condition that can cause long-term damage to a child’s health. It is important to understand the signs and symptoms of this condition to ensure that children are protected from harm. While the controversy surrounding the diagnosis of shaken baby syndrome continues, it is crucial to prioritize the safety and well-being of children. By raising awareness and educating the public about this condition, we can work towards preventing it from occurring in the future.

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      • Paediatrics
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  • Question 23 - A 6-month-old girl is brought to the emergency department by her worried father....

    Correct

    • A 6-month-old girl is brought to the emergency department by her worried father. He reports that she has had a low-grade fever and a runny nose for the past week, and in the last few days, she has been struggling to breathe and making grunting noises. He is concerned because she is not eating well and her diapers are not as wet as usual. Upon examination, you observe chest retractions, wheezing, and bilateral inspiratory crackles.
      What is the most suitable treatment for the probable diagnosis?

      Your Answer: Admit for supportive treatment

      Explanation:

      The appropriate action for a child with bronchiolitis is to admit them for supportive treatment, as antibiotics are not necessary. This condition is typically caused by RSV and can be managed with supportive care. However, if the child is experiencing severe respiratory distress and a significant reduction in feeding, they should be admitted to the hospital for treatment. Admitting for IV antibiotics would not be appropriate unless pneumonia or another bacterial infection was suspected. Salbutamol nebulisers are not typically effective for bronchiolitis. Discharging the child home with advice or oral antibiotics would not be appropriate if they are showing signs of potentially serious illness.

      Bronchiolitis is a condition where the bronchioles become inflamed, and it is most commonly caused by respiratory syncytial virus (RSV). This virus is responsible for 75-80% of cases, with other causes including mycoplasma and adenoviruses. Bronchiolitis is most prevalent in infants under one year old, with 90% of cases occurring in those aged 1-9 months. The condition is more serious in premature babies, those with congenital heart disease or cystic fibrosis. Symptoms include coryzal symptoms, dry cough, increasing breathlessness, and wheezing. Hospital admission is often necessary due to feeding difficulties associated with increasing dyspnoea.

      Immediate referral is recommended if the child has apnoea, looks seriously unwell, has severe respiratory distress, central cyanosis, or persistent oxygen saturation of less than 92% when breathing air. Clinicians should consider referral if the child has a respiratory rate of over 60 breaths/minute, difficulty with breastfeeding or inadequate oral fluid intake, or clinical dehydration. Immunofluorescence of nasopharyngeal secretions may show RSV, and management is largely supportive. Humidified oxygen is given via a head box if oxygen saturations are persistently low, and nasogastric feeding may be necessary if children cannot take enough fluid/feed by mouth. Suction may also be used for excessive upper airway secretions. NICE released guidelines on bronchiolitis in 2015 for more information.

    • This question is part of the following fields:

      • Paediatrics
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  • Question 24 - A 4-year-old girl is brought to the GP by her father. He has...

    Correct

    • A 4-year-old girl is brought to the GP by her father. He has noticed a red rash on the flexor aspects of her knees and on the neck and reports she is constantly trying to scratch. On examination the child appears well. There is evidence of excoriation over red patches of dry skin but there is no crusting or evidence of infection. A diagnosis of eczema is made. What is the first line treatment in a child of this age?

      Your Answer: Topical emollients

      Explanation:

      When managing eczema in children who have just been diagnosed and have not received any treatment, the initial step is to prescribe topical emollients as the first-line treatment. If the symptoms persist, topical steroids can be used in conjunction with emollients, but it is important to ensure that emollients are used before adding steroids.

      Eczema in Children: Symptoms and Management

      Eczema is a common skin condition that affects around 15-20% of children and is becoming more prevalent. It usually appears before the age of 2 and clears up in around 50% of children by the age of 5 and in 75% of children by the age of 10. The symptoms of eczema include an itchy, red rash that can worsen with repeated scratching. In infants, the face and trunk are often affected, while in younger children, it typically occurs on the extensor surfaces. In older children, the rash is more commonly seen on the flexor surfaces and in the creases of the face and neck.

      To manage eczema in children, it is important to avoid irritants and use simple emollients. Large quantities of emollients should be prescribed, roughly in a ratio of 10:1 with topical steroids. If a topical steroid is also being used, the emollient should be applied first, followed by waiting at least 30 minutes before applying the topical steroid. Creams are absorbed into the skin faster than ointments, and emollients can become contaminated with bacteria, so fingers should not be inserted into pots. Many brands have pump dispensers to prevent contamination.

      In severe cases, wet wrapping may be used, which involves applying large amounts of emollient (and sometimes topical steroids) under wet bandages. Oral ciclosporin may also be used in severe cases. Overall, managing eczema in children involves a combination of avoiding irritants, using emollients, and potentially using topical steroids or other medications in severe cases.

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      • Paediatrics
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  • Question 25 - You are working on the neonatal ward and are called to see a...

    Incorrect

    • You are working on the neonatal ward and are called to see a newborn who the nurses have noticed is persistently 'floppy'. You assess the newborn and find no acute cause for concern and wonder whether there might be an underlying issue.
      Which of the following is most likely to be the underlying cause of neonatal hypotonia in this case?

      Your Answer: Becker Muscular Dystrophy

      Correct Answer: Prader-Willi syndrome

      Explanation:

      Prader-Willi is one of the conditions that can cause neonatal hypotonia, along with neonatal sepsis, spinal muscular atrophy, and hypothyroidism.

      Understanding Neonatal Hypotonia and Its Causes

      Neonatal hypotonia is a condition characterized by low muscle tone in newborns. This can be caused by various factors, including neonatal sepsis, Werdnig-Hoffman disease (spinal muscular atrophy type 1), hypothyroidism, and Prader-Willi syndrome. Maternal factors such as drug use, particularly benzodiazepines, and myasthenia gravis can also contribute to neonatal hypotonia.

      Neonatal hypotonia can have serious consequences, including difficulty with feeding and breathing, delayed motor development, and even death in severe cases. It is important for healthcare providers to identify the underlying cause of hypotonia in newborns and provide appropriate treatment to prevent complications and improve outcomes.

      Understanding the potential causes of neonatal hypotonia can help healthcare providers make an accurate diagnosis and develop an effective treatment plan. With proper care and management, many newborns with hypotonia can go on to lead healthy and fulfilling lives.

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      • Paediatrics
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  • Question 26 - A 5-year-old girl was released from the hospital eight weeks ago following an...

    Incorrect

    • A 5-year-old girl was released from the hospital eight weeks ago following an episode of viral gastroenteritis. She has been experiencing 4-5 loose stools per day for the past six weeks. What is the probable diagnosis?

      Your Answer: Clostridium difficile infection

      Correct Answer: Lactose intolerance

      Explanation:

      Viral gastroenteritis often leads to transient lactose intolerance, which can be resolved by eliminating lactose from the diet for a few months and then gradually reintroducing it.

      Understanding Diarrhoea in Children

      Diarrhoea is a common condition in children that can be caused by various factors. One of the most common causes is gastroenteritis, which is often accompanied by fever and vomiting for the first two days. The main risk associated with this condition is severe dehydration, which can be life-threatening if left untreated. The most common cause of gastroenteritis is rotavirus, and the diarrhoea may last up to a week. The treatment for this condition is rehydration.

      Chronic diarrhoea is another type of diarrhoea that can affect infants and toddlers. In the developed world, the most common cause of chronic diarrhoea in infants is cow’s’ milk intolerance. Toddler diarrhoea, on the other hand, is characterized by stools that vary in consistency and often contain undigested food. Other causes of chronic diarrhoea in children include coeliac disease and post-gastroenteritis lactose intolerance.

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      • Paediatrics
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  • Question 27 - A 7-year-old boy is brought into the Emergency Department by his worried parents,...

    Correct

    • A 7-year-old boy is brought into the Emergency Department by his worried parents, who have noticed he is covered in a rash and has developed numerous bruises on his legs. This has come on suddenly and he has been well, apart from a ‘cold’ that he got over around 2 weeks previously. He has no past medical history of note, apart from undergoing an uncomplicated tonsillectomy aged 5 years following recurrent tonsillitis. There is no family history of any bleeding disorders. There is no history of fever within the last 24 hours.
      On examination, vital signs are normal. There is a purpuric rash to all four limbs and his trunk. A few red spots are noted on the oral mucosa. Physical examination is otherwise unremarkable, without lymphadenopathy and no hepatosplenomegaly. Fundi are normal.
      A full blood count and urine dipstick are performed and yield the following results:
      Investigation Result Normal value
      Haemoglobin 132 g/l 115–140 g/l
      White cell count 4.8 × 109/l 4–11 × 109/l
      Platelets 25 × 109/l 150–400 × 109/l
      Blood film thrombocytopenia
      Urine dipstick no abnormality detected
      What is the most likely diagnosis?

      Your Answer: Idiopathic thrombocytopenic purpura (ITP)

      Explanation:

      Pediatric Hematologic Conditions: ITP, AML, NAI, HSP, and SLE

      Idiopathic thrombocytopenic purpura (ITP) is an autoimmune condition that causes thrombocytopenia and presents with a red-purple purpuric rash. Acute myeloid leukemia (AML) presents with bone marrow failure, resulting in anemia and thrombocytopenia. Non-accidental injury (NAI) is unlikely in cases of thrombocytopenia, as blood tests are typically normal. Henoch-Schönlein purpura (HSP) is an IgA-mediated vasculitis that primarily affects children and presents with a petechial purpuric rash, arthralgia, and haematuria. Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that affects multiple organs and presents with a malar rash, proteinuria, thrombocytopenia, haemolytic anaemia, fever, seizures, and lymphadenopathy.

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      • Paediatrics
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  • Question 28 - A 4-year-old girl is brought into resus in cardiac arrest. The patient was...

    Correct

    • A 4-year-old girl is brought into resus in cardiac arrest. The patient was brought in by ambulance with her father. He is too distraught to give any history other than the child had been okay when he had left the room. She was found unconscious on his return so an ambulance was called.
      Which of the reversible causes of cardiac arrest are most likely in this situation?

      Your Answer: Hypoxia

      Explanation:

      Respiratory arrest is the most frequent reason for children’s arrest, with hypoxia being the probable cause in this case. Choking incidents are a common cause of collapse and arrest in young children who are able to walk, particularly toddlers, due to their age and the absence of a clear history for another cause. Hypovolaemia and tension pneumothorax are less likely since there is no indication of trauma in the history, and hypothermia is not a factor.

      Paediatric Basic Life Support Guidelines

      Paediatric basic life support guidelines were updated in 2015 by the Resuscitation Council. Lay rescuers should use a compression:ventilation ratio of 30:2 for children under 1 year and between 1 year and puberty, a child is defined. If there are two or more rescuers, a ratio of 15:2 should be used.

      The algorithm for paediatric basic life support starts with checking if the child is unresponsive and shouting for help. The airway should be opened, and breathing should be checked by looking, listening, and feeling for breaths. If the child is not breathing, five rescue breaths should be given, and signs of circulation should be checked.

      For infants, the brachial or femoral pulse should be used, while children should use the femoral pulse. Chest compressions should be performed at a ratio of 15:2, with a rate of 100-120 compressions per minute for both infants and children. The depth of compressions should be at least one-third of the anterior-posterior dimension of the chest, which is approximately 4 cm for an infant and 5 cm for a child.

      In children, the lower half of the sternum should be compressed, while in infants, a two-thumb encircling technique should be used for chest compressions. These guidelines are crucial for anyone who may need to perform basic life support on a child, and it is essential to follow them carefully to ensure the best possible outcome.

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      • Paediatrics
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  • Question 29 - Liam, a 13-year-old with learning difficulties, visits his GP clinic. Following a practice...

    Correct

    • Liam, a 13-year-old with learning difficulties, visits his GP clinic. Following a practice meeting, it is concluded that Liam does not possess the capacity to make decisions regarding his medical treatment. What principles should be prioritized when making decisions for Liam?

      Your Answer: Consent may be given by one parent for the treatment that is in her best interests

      Explanation:

      The GMC provides comprehensive guidance on obtaining consent from children. In cases where a child is incapable of giving consent, the agreement of one parent is adequate for treatment to be administered, provided it is in the child’s best interests. It is also crucial to involve Dawn in the decision-making process, despite her incapacity.

      Guidelines for Obtaining Consent in Children

      The General Medical Council has provided guidelines for obtaining consent in children. According to these guidelines, young people who are 16 years or older can be treated as adults and are presumed to have the capacity to make decisions. However, for children under the age of 16, their ability to understand what is involved determines whether they have the capacity to decide. If a competent child refuses treatment, a person with parental responsibility or the court may authorize investigation or treatment that is in the child’s best interests.

      When it comes to providing contraceptives to patients under 16 years of age, the Fraser Guidelines must be followed. These guidelines state that the young person must understand the professional’s advice, cannot be persuaded to inform their parents, is likely to begin or continue having sexual intercourse with or without contraceptive treatment, and will suffer physical or mental health consequences without contraceptive treatment. Additionally, the young person’s best interests require them to receive contraceptive advice or treatment with or without parental consent.

      Some doctors use the term Fraser competency when referring to contraception and Gillick competency when referring to general issues of consent in children. However, rumors that Victoria Gillick removed her permission to use her name or applied copyright have been debunked. It is important to note that in Scotland, those with parental responsibility cannot authorize procedures that a competent child has refused.

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      • Paediatrics
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  • Question 30 - A 3-year-old girl with several small bruise-like lesions is brought to the emergency...

    Incorrect

    • A 3-year-old girl with several small bruise-like lesions is brought to the emergency department by her father. He reports first noticing these lesions on his daughter's arm when dressing her three days ago, despite no obvious preceding trauma. The bruising does not appear to be spreading.
      Notably, the child had mild cough and fever symptoms two weeks ago, though has now recovered.
      On examination, the child appears well in herself and is playing with toys. There are 3 small petechiae on the patient's arm. The examination is otherwise unremarkable.
      What would be an indication for bone marrow biopsy, given the likely diagnosis?

      Your Answer: Thrombocytopenia

      Correct Answer: Splenomegaly

      Explanation:

      Bone marrow examination is not necessary for children with immune thrombocytopenia (ITP) unless there are atypical features such as splenomegaly, bone pain, or diffuse lymphadenopathy. ITP is an autoimmune disorder that causes the destruction of platelets, often triggered by a viral illness. Folate deficiency, photophobia, and epistaxis are not indications for bone marrow biopsy in children with ITP. While photophobia may suggest meningitis in a patient with a petechial rash, it does not warrant a bone marrow biopsy. Nosebleeds are common in young children with ITP and do not require a bone marrow biopsy.

      Understanding Immune Thrombocytopenia (ITP) in Children

      Immune thrombocytopenic purpura (ITP) is a condition where the immune system attacks the platelets, leading to a decrease in their count. This condition is more common in children and is usually acute, often following an infection or vaccination. The antibodies produced by the immune system target the glycoprotein IIb/IIIa or Ib-V-IX complex, causing a type II hypersensitivity reaction.

      The symptoms of ITP in children include bruising, a petechial or purpuric rash, and less commonly, bleeding from the nose or gums. A full blood count is usually sufficient to diagnose ITP, and a bone marrow examination is only necessary if there are atypical features.

      In most cases, ITP resolves on its own within six months, without any treatment. However, if the platelet count is very low or there is significant bleeding, treatment options such as oral or IV corticosteroids, IV immunoglobulins, or platelet transfusions may be necessary. It is also advisable to avoid activities that may result in trauma, such as team sports. Understanding ITP in children is crucial for prompt diagnosis and management of this condition.

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      • Paediatrics
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SESSION STATS - PERFORMANCE PER SPECIALTY

Paediatrics (21/30) 70%
Passmed