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Question 1
Incorrect
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A 28-year-old woman is admitted to the psychiatric ward under section 2 of the mental health act for suspected bipolar disorder. She has a 4-month history of manic episodes and has been experiencing delusions of grandeur. She started lithium 3 weeks ago. She has no other medical conditions and takes no other medications. Today, staff on the ward raised concerns due to her abnormal behaviour. She was found in the common room dancing and singing loudly, despite it being late at night. It is reported that she has been like this for the last hour. Her observations are normal. She has not responded to attempts to engage her in conversation or to calm her down. What is the most appropriate description of her current presentation?
Your Answer: Serotonin syndrome
Correct Answer: Catatonia
Explanation:The most likely cause of the woman’s presentation, who is suspected to have schizophrenia and has been sitting in an uncomfortable position for the last 2 hours, is catatonia. Catatonia is a condition where voluntary movement is stopped or the person stays in an unusual position. It is believed to occur due to abnormalities in the balance of neurotransmitter systems, particularly dopamine, and is commonly associated with certain types of schizophrenia. Treatment for catatonia includes benzodiazepines and electroconvulsive therapy.
Extrapyramidal side effects, neuroleptic malignant syndrome, and serotonin syndrome are not the correct answers for this scenario. Extrapyramidal side effects can occur with antipsychotic medications but would not present with the withdrawn status described. Neuroleptic malignant syndrome is a life-threatening reaction to antipsychotic medications and presents with different symptoms than catatonia. Serotonin syndrome is caused by excess serotonin in the body and is not associated with the patient’s medication or presentation.
Schizophrenia is a mental disorder that is characterized by various symptoms. Schneider’s first rank symptoms are divided into four categories: auditory hallucinations, thought disorders, passivity phenomena, and delusional perceptions. Auditory hallucinations can include hearing two or more voices discussing the patient in the third person, thought echo, or voices commenting on the patient’s behavior. Thought disorders can involve thought insertion, thought withdrawal, or thought broadcasting. Passivity phenomena can include bodily sensations being controlled by external influence or actions/impulses/feelings that are imposed on the individual or influenced by others. Delusional perceptions involve a two-stage process where a normal object is perceived, and then there is a sudden intense delusional insight into the object’s meaning for the patient.
Other features of schizophrenia include impaired insight, incongruity/blunting of affect (inappropriate emotion for circumstances), decreased speech, neologisms (made-up words), catatonia, and negative symptoms such as incongruity/blunting of affect, anhedonia (inability to derive pleasure), alogia (poverty of speech), and avolition (poor motivation). It is important to note that schizophrenia can manifest differently in each individual, and not all symptoms may be present.
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This question is part of the following fields:
- Psychiatry
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Question 2
Incorrect
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A 42-year-old male has arrived at the emergency department after experiencing a witnessed seizure. According to the witness, the seizure lasted around 10 minutes and the patient was drowsy for 15 minutes afterward. The patient is now alert and conversing with the medical staff. They have a history of schizophrenia and have reported several seizures since beginning a new medication five weeks ago. Which medication is the most probable cause of this incident?
Your Answer: Olanzapine
Correct Answer: Clozapine
Explanation:Clozapine is the only atypical antipsychotic drug that reduces seizure threshold, increasing the likelihood of seizures. While effective, it has serious side effects such as agranulocytosis, neutropenia, reduced seizure threshold, and myocarditis. Aripiprazole has a favorable side effect profile and is less likely to cause hyperprolactinemia or other side effects. Olanzapine is known for causing dyslipidemia, weight gain, diabetes, and sedation, but may be prescribed to underweight patients who have trouble sleeping. Quetiapine is associated with weight gain, dyslipidemia, and postural hypotension.
Atypical antipsychotics are now recommended as the first-line treatment for patients with schizophrenia, as per the 2005 NICE guidelines. These medications have the advantage of significantly reducing extrapyramidal side-effects. However, they can also cause adverse effects such as weight gain, hyperprolactinaemia, and in the case of clozapine, agranulocytosis. The Medicines and Healthcare products Regulatory Agency has issued warnings about the increased risk of stroke and venous thromboembolism when antipsychotics are used in elderly patients. Examples of atypical antipsychotics include clozapine, olanzapine, risperidone, quetiapine, amisulpride, and aripiprazole.
Clozapine, one of the first atypical antipsychotics, carries a significant risk of agranulocytosis and requires full blood count monitoring during treatment. Therefore, it should only be used in patients who are resistant to other antipsychotic medication. The BNF recommends introducing clozapine if schizophrenia is not controlled despite the sequential use of two or more antipsychotic drugs, one of which should be a second-generation antipsychotic drug, each for at least 6-8 weeks. Adverse effects of clozapine include agranulocytosis, neutropaenia, reduced seizure threshold, constipation, myocarditis, and hypersalivation. Dose adjustment of clozapine may be necessary if smoking is started or stopped during treatment.
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This question is part of the following fields:
- Psychiatry
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Question 3
Incorrect
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A 28-year-old woman presents to the emergency department with a decreased level of consciousness. Upon evaluation, her blood sugar is found to be 1.2 and is treated accordingly. The paramedics report finding her next to an insulin syringe, despite her not having diabetes. This is the third occurrence of such an event, and the patient denies any suicidal ideation. What is the diagnosis for this woman's condition?
Your Answer: Somatization disorder
Correct Answer: Munchausen's syndrome
Explanation:Deliberately inducing symptoms, such as a diabetic intentionally overdosing on insulin to experience hypoglycemia, is an instance of Munchausen’s syndrome.
Psychiatric Terms for Unexplained Symptoms
There are various psychiatric terms used to describe patients who exhibit symptoms for which no organic cause can be found. One such disorder is somatisation disorder, which involves the presence of multiple physical symptoms for at least two years, and the patient’s refusal to accept reassurance or negative test results. Another disorder is illness anxiety disorder, which is characterized by a persistent belief in the presence of an underlying serious disease, such as cancer, despite negative test results.
Conversion disorder is another condition that involves the loss of motor or sensory function, and the patient does not consciously feign the symptoms or seek material gain. Patients with this disorder may be indifferent to their apparent disorder, a phenomenon known as la belle indifference. Dissociative disorder, on the other hand, involves the process of ‘separating off’ certain memories from normal consciousness, and may manifest as amnesia, fugue, or stupor. Dissociative identity disorder (DID) is the most severe form of dissociative disorder and was previously known as multiple personality disorder.
Factitious disorder, also known as Munchausen’s syndrome, involves the intentional production of physical or psychological symptoms. Finally, malingering is the fraudulent simulation or exaggeration of symptoms with the intention of financial or other gain. Understanding these psychiatric terms can help healthcare professionals better diagnose and treat patients with unexplained symptoms.
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This question is part of the following fields:
- Psychiatry
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Question 4
Incorrect
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A 26-year-old man presents to your clinic six months after he was assaulted on his way home from work. He was mugged and punched in the stomach by his attacker before he fled. Six months later, the patient continues to have severe and incapacitating periumbilical pain where he was punched. He denies any gastrointestinal symptoms or any other issues. Previous investigations and imaging have been unremarkable for any underlying anatomical, neurological or vascular abnormality.
What is the most appropriate description of the patient's current complaints during the clinic visit?Your Answer: Post-traumatic stress disorder (PTSD)
Correct Answer: Pain disorder
Explanation:Differentiating between Psychiatric Disorders: Pain Disorder, Conversion Disorder, Somatization Disorder, PTSD, and Acute Stress Disorder
When evaluating a patient with unexplained physical symptoms, it is important to consider various psychiatric disorders that may be contributing to their presentation. In this case, the patient’s symptoms do not fit the criteria for somatization disorder, PTSD, or acute stress disorder. However, there are other disorders that should be considered.
Pain disorder is characterized by intense, long-standing pain without a somatic explanation. The patient’s pain is out of proportion to the injury and is not explained by any underlying somatic pathology. This disorder is restricted to physical pain and does not include other somatic complaints.
Conversion disorder, on the other hand, presents as a neurological deficit in the absence of a somatic cause. Patients are usually unconcerned about the symptom, unlike this patient. It usually follows a psychosocial stressor.
Somatization disorder refers to patients with a constellation of physical complaints that are not explained by a somatic process. This would include odd distributions of pain, numbness, GI upset, headache, nausea, vomiting, shortness of breath, palpitations, etc. However, this patient is fixated on a particular disease and does not fit the criteria for somatization.
PTSD presents with persistent re-experiencing of the trauma, nightmares, flashbacks, intense fear, avoidant behaviour and/or increased arousal. Symptoms must persist for at least 1 month and impair his quality of life. There are no clear signs of PTSD in this patient.
Acute stress disorder is an anxiety condition precipitated by an acute stress that resolves within a month. This is well beyond the window for acute stress, and it does not fit the symptomatology of acute stress.
In conclusion, it is important to consider various psychiatric disorders when evaluating a patient with unexplained physical symptoms. By ruling out certain disorders, a proper diagnosis and treatment plan can be established.
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This question is part of the following fields:
- Psychiatry
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Question 5
Correct
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A 39-year-old man, with a history of severe depression, is admitted unconscious to the hospital, following a suicide attempt where he stabbed himself with a knife, with significant intent of causing death. His past psychiatric history suggests that this is his fifth suicide attempt, with the four previous attempts involving taking an overdose of his antidepressants and paracetamol. During this admission, he needed surgery for bowel repair. He is now three days post-operation on the Surgical Ward and is having one-to-one nursing due to recurrent suicidal thoughts after his surgery. The consulting surgeon thinks he is not fit enough to be discharged, and a referral is made to liaison psychiatry. After assessing the patient, the psychiatrist reports that the patient’s current severe depression is affecting his capacity and that the patient’s mental health puts himself at risk of harm. The psychiatrist decides to detain him on the ward for at least three days. The patient insists on leaving and maintains that he has no interest to be alive.
Which is the most appropriate section for the doctor to use to keep this patient in hospital?Your Answer: Section 5(2)
Explanation:The Mental Health Act has several sections that allow doctors and mental health professionals to keep patients in hospital for assessment or treatment. Section 5(2) can be used by doctors to keep a patient in hospital for at least 72 hours if they have a history of severe depression, previous suicide attempts, or recurrent suicidal thoughts. Section 2 is used by approved mental health professionals for assessment and allows for a maximum stay of 28 days. Section 4 is used in emergencies and allows for a 72-hour stay. Section 5(4) can be used by mental health or learning disability nurses for a maximum of six hours. Section 3 can be used for treatment for up to six months, with the possibility of extensions and treatment against the patient’s will in the first three months.
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This question is part of the following fields:
- Psychiatry
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Question 6
Correct
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A 30-year-old woman visits her General Practitioner (GP) with complaints of insomnia. She reports feeling persistently anxious and unable to cease worrying about everything. The GP suspects she may have an anxiety disorder.
What is the most effective tool to use in making a diagnosis?Your Answer: Generalised Anxiety Disorder Questionnaire (GAD-7)
Explanation:Common Screening Tools for Mental Health Conditions
There are several screening tools used in healthcare settings to identify and monitor mental health conditions. These tools help healthcare professionals assess the severity of symptoms and determine appropriate treatment plans. Here are some commonly used screening tools:
1. Generalised Anxiety Disorder Questionnaire (GAD-7): This questionnaire consists of seven questions and is used to screen for generalised anxiety disorder. It measures the severity of symptoms as mild, moderate, or severe.
2. Alcohol Use Disorders Identification Test (AUDIT): The AUDIT is a screening tool used to identify signs of harmful drinking and dependence on alcohol.
3. Mini-Mental State Examination (MMSE): The MMSE is a questionnaire consisting of 30 questions used to identify cognitive impairment. It is commonly used to screen for dementia.
4. Modified Single-Answer Screening Question (M SASQ): The M SASQ is a single-question alcohol-harm assessment tool designed for use in Emergency Departments. It identifies high-risk drinkers based on their frequency of consuming six or more units (if female, or eight or more if male) on a single occasion in the last year.
5. Patient Health Questionnaire (PHQ-9): The PHQ-9 is used in primary care to monitor the severity of depression and the response to treatment. It uses each of the nine Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria for a diagnosis of depression and scores each domain depending on how often the patient experiences these symptoms.
These screening tools are valuable resources for healthcare professionals to identify and monitor mental health conditions. By using these tools, healthcare professionals can provide appropriate treatment and support to their patients.
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This question is part of the following fields:
- Psychiatry
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Question 7
Incorrect
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A 25-year-old man arrives at the emergency department following his fifth suicide attempt in the past two years. He was discovered by his ex-girlfriend, who ended their relationship the day before due to his intense mood swings and overwhelmingly negative emotions. He has no communication with his family and appears unkempt. When questioned, he expresses feelings of worthlessness and a belief that everyone will eventually leave him. What is the probable diagnosis?
Your Answer: Major depressive disorder
Correct Answer: Emotionally unstable personality disorder (EUPD)
Explanation:The correct diagnosis for this patient is emotionally unstable personality disorder. This disorder is characterized by impulsive behavior, disturbances in self-image, and a fear of abandonment. Patients with this disorder often experience severe mood swings and intense negative emotions, including explosive anger outbursts and a chronic sense of emptiness. They tend to have intense relationships with others and may have a history of self-harm or suicide attempts.
Bipolar disorder is an incorrect diagnosis as there is no evidence of past manic episodes. Histrionic personality disorder is also incorrect as the patient does not exhibit the typical attention-seeking behavior and preoccupation with physical appearance. Major depressive disorder is also not the correct diagnosis as it does not account for the patient’s intense interpersonal relationships and fear of abandonment.
Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.
Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspiratorial beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.
Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.
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This question is part of the following fields:
- Psychiatry
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Question 8
Incorrect
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A 23-year-old woman is brought to the Emergency Department by her friend. The friend reports that she has been acting strangely and unable to focus on one task at a time. He has observed over the past few days that she has been walking around in the early hours of the morning and not sleeping. He is particularly concerned that she has been returning home with multiple bags of expensive shopping every day for the past three days.
The patient denies experiencing any hallucinations but reports feeling fantastic and having an increased appetite. She has no prior medical history and is not taking any medications.
What is the most probable cause of this patient's presentation?Your Answer: Mania
Correct Answer: Hypomania
Explanation:The patient is displaying signs of hypomania, which is characterized by an elevated mood, pressured speech, and flight of ideas, but without any psychotic symptoms. She is experiencing agitation, insomnia, and an increased appetite. Patients with hypomania may also exhibit disinhibition, such as increased sexuality, spending, or risk-taking behaviors. Hypomania differs from mania in terms of duration (less than 7 days) and the absence of hallucinations. The patient’s history does not suggest any prior episodes of depression, so hypomania is the most appropriate diagnosis at this time. Frontal lobe injury can cause motor symptoms, speech difficulties, and disinhibition, but there is no indication of this in the patient’s history. Mania is more severe than hypomania and lasts longer than 7 days, often involving psychotic symptoms such as hallucinations or delusions, which are not present in this case. The patient is not exhibiting any signs of psychosis, which can also involve thought disorganization, such as tangentiality, word salad, and poverty of speech.
Understanding the Difference between Hypomania and Mania
Hypomania and mania are two terms that are often used interchangeably, but they actually refer to two different conditions. While both conditions share some common symptoms, there are some key differences that set them apart.
Mania is a more severe form of hypomania that lasts for at least seven days and can cause significant impairment in social and work settings. It may require hospitalization due to the risk of harm to oneself or others and may present with psychotic symptoms such as delusions of grandeur or auditory hallucinations.
On the other hand, hypomania is a lesser version of mania that lasts for less than seven days, typically 3-4 days. It does not impair functional capacity in social or work settings and is unlikely to require hospitalization. It also does not exhibit any psychotic symptoms.
Both hypomania and mania share common symptoms such as elevated or irritable mood, pressured speech, flight of ideas, poor attention, insomnia, loss of inhibitions, increased appetite, and risk-taking behavior. However, the length of symptoms, severity, and presence of psychotic symptoms help differentiate mania from hypomania.
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This question is part of the following fields:
- Psychiatry
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Question 9
Correct
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A 26-year-old female patient visits her general practitioner with concerns about her interpersonal relationships both at work and in her personal life. She reveals that this has been a persistent issue since her teenage years. She finds it challenging to collaborate with others and identifies herself as a perfectionist. Additionally, she has been described by others as rigid. What personality disorder is indicated by these symptoms?
Your Answer: Obsessive-compulsive personality disorder
Explanation:Patients diagnosed with obsessive-compulsive personality disorder tend to have inflexible attitudes towards morals, ethics, and values, and are often hesitant to delegate tasks to others. They exhibit perfectionistic tendencies and adhere to strict protocols in their work. This disorder makes it challenging for them to collaborate with others and adapt to different ways of doing things.
Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.
Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspiratorial beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.
Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.
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This question is part of the following fields:
- Psychiatry
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Question 10
Incorrect
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A 35-year-old male comes to your clinic at the suggestion of his partner. He has been experiencing hyperarousal to loud noises and difficulty concentrating at work since his stay in the ICU 4 weeks ago. His partner believes he may have acute stress disorder, but you diagnose him with PTSD and discuss treatment options. He asks you to explain the difference between the two to his partner. You explain that while the presentation is similar, the main difference is temporal.
At what point after the event can you confirm a diagnosis of PTSD?Your Answer: 12 weeks
Correct Answer: 4 weeks
Explanation:Acute stress disorder is characterized by an acute stress reaction that occurs within four weeks of a traumatic event, while PTSD is diagnosed after four weeks have passed. Symptoms presented within two weeks would suggest acute stress disorder. Both acute stress disorder and PTSD share similar features, including re-experiencing, avoidance, hyperarousal, and emotional numbing. Re-experiencing symptoms may include flashbacks, nightmares, and repetitive and distressing intrusive images. Avoidance symptoms may involve avoiding people, situations, or circumstances associated with the traumatic event. Hyperarousal symptoms may include hypervigilance for threat, exaggerated startle response, sleep problems, irritability, and difficulty concentrating. Emotional numbing may result in a lack of ability to experience feelings and feeling detached.
Acute stress disorder is a condition that occurs within the first four weeks after a person has experienced a traumatic event, such as a life-threatening situation or sexual assault. It is characterized by symptoms such as intrusive thoughts, dissociation, negative mood, avoidance, and arousal. These symptoms can include flashbacks, nightmares, feeling disconnected from reality, and being hypervigilant.
To manage acute stress disorder, trauma-focused cognitive-behavioral therapy (CBT) is typically the first-line treatment. This type of therapy helps individuals process their traumatic experiences and develop coping strategies. In some cases, benzodiazepines may be used to alleviate acute symptoms such as agitation and sleep disturbance. However, caution must be taken when using these medications due to their addictive potential and potential negative impact on adaptation. Overall, early intervention and appropriate treatment can help individuals recover from acute stress disorder and prevent the development of more chronic conditions such as PTSD.
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This question is part of the following fields:
- Psychiatry
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