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Question 1
Incorrect
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A 23 year old female presents for a routine contraception pill check. She has been taking co-cyprindiol for the past year. Her blood pressure and BMI are normal, she doesn't smoke, and has no personal or family history of stroke, venous thromboembolism, or migraine. She previously had acne but reports it has been clear for the past 4 months and wishes to continue on the same pill. She is in a committed relationship. What is the best course of action?
Your Answer: Continue co-cyprindiol and review again routinely in 12 months
Correct Answer: Discontinue co-cyprindiol and change to standard combined oral contraceptive pill
Explanation:The MHRA recommends discontinuing co-cyprindiol (Dianette) 3-4 cycles after acne has cleared due to the increased risk of venous thromboembolism. It should not be used solely for contraception. However, the patient still requires contraception, and a combined pill may offer better contraceptive coverage than a progesterone-only pill, while also providing some benefit for her skin. Other contraceptive options should also be considered.
Acne vulgaris is a common skin condition that usually affects teenagers and is characterized by the obstruction of hair follicles with keratin plugs, resulting in comedones, inflammation, and pustules. The severity of acne can be classified as mild, moderate, or severe, depending on the number and type of lesions present. Treatment for acne typically involves a step-up approach, starting with single topical therapy and progressing to combination therapy or oral antibiotics if necessary. Tetracyclines are commonly used but should be avoided in certain populations, and a topical retinoid or benzoyl peroxide should always be co-prescribed to reduce the risk of antibiotic resistance. Combined oral contraceptives can also be used in women, and oral isotretinoin is reserved for severe cases under specialist supervision. Dietary modification has no role in the management of acne.
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This question is part of the following fields:
- Dermatology
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Question 2
Correct
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A 25-year-old woman is distressed about her acne vulgaris with papules, pustules and comedones. Her weight and periods are both normal. Identify the probable cause from the options provided.
Your Answer: Bacteria
Explanation:Understanding Acne in Women: Causes and Treatments
Acne is not just a teenage problem, especially for women. There are several factors that contribute to its development, including genetics, seborrhoea, sensitivity to androgen, P. acnes bacteria, blocked hair follicles, and immune system response. Polycystic ovarian syndrome is a less common cause of acne. Treatment options target these underlying causes, with combined oral contraceptives being a popular choice. Contrary to popular belief, diet and hygiene do not play a significant role in acne. The black color of blackheads is due to pigment in the hair follicle material. Understanding the causes and treatments of acne can help women manage this common skin condition.
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This question is part of the following fields:
- Dermatology
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Question 3
Correct
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Acne vulgaris is a common presentation to GP. One treatment option is an oral antibiotic, and tetracyclines are the first line. From the options below which patient would be suitable to receive oral tetracycline if they are 16 years old or above?
Your Answer: A 16-year-old female
Explanation:When treating acne with oral antibiotics, tetracyclines are typically the first choice. All tetracyclines are effective for treating acne, so the decision on which one to use should be based on personal preference and cost. Tetracycline and oxytetracycline are taken twice a day on an empty stomach, while doxycycline and lymecycline are taken once a day and can be taken with food. However, pregnant or breastfeeding women and children under 12 should avoid oral tetracyclines due to the risk of them being deposited in the developing child’s teeth and bones. Women of childbearing age who are taking a topical retinoid should use effective contraception. If tetracyclines are not an option, erythromycin can be used instead at a dose of 500 mg twice a day. In this case, a 16-year-old female would be a suitable candidate for tetracyclines.
Acne vulgaris is a common skin condition that usually affects teenagers and is characterized by the obstruction of hair follicles with keratin plugs, resulting in comedones, inflammation, and pustules. The severity of acne can be classified as mild, moderate, or severe, depending on the number and type of lesions present. Treatment for acne typically involves a step-up approach, starting with single topical therapy and progressing to combination therapy or oral antibiotics if necessary. Tetracyclines are commonly used but should be avoided in certain populations, and a topical retinoid or benzoyl peroxide should always be co-prescribed to reduce the risk of antibiotic resistance. Combined oral contraceptives can also be used in women, and oral isotretinoin is reserved for severe cases under specialist supervision. Dietary modification has no role in the management of acne.
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This question is part of the following fields:
- Dermatology
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Question 4
Incorrect
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A 55-year-old woman comes in with a persistent erythematous rash on her cheeks and a 'red nose'. She reports experiencing occasional facial flushing. During examination, erythematous skin is observed on the nose and cheeks, along with occasional papules. What is the best course of action for management?
Your Answer: Topical hydrocortisone
Correct Answer: Topical metronidazole
Explanation:For the treatment of mild rosacea symptoms, the recommended first-line option is topical metronidazole. However, if the symptoms are severe or resistant, oral tetracycline may be necessary.
Rosacea, also known as acne rosacea, is a skin condition that is chronic in nature and its cause is unknown. It typically affects the nose, cheeks, and forehead, and the first symptom is often flushing. Telangiectasia, which are small blood vessels that are visible on the skin, are common, and the condition can progress to persistent erythema with papules and pustules. Rhinophyma, a condition where the nose becomes enlarged and bulbous, can also occur. Ocular involvement, such as blepharitis, can also be present, and sunlight can exacerbate symptoms.
Management of rosacea depends on the severity of the symptoms. For mild symptoms, topical metronidazole may be used, while topical brimonidine gel may be considered for patients with predominant flushing but limited telangiectasia. More severe cases may require systemic antibiotics such as oxytetracycline. It is recommended that patients apply a high-factor sunscreen daily and use camouflage creams to conceal redness. Laser therapy may be appropriate for patients with prominent telangiectasia, and those with rhinophyma should be referred to a dermatologist for further management.
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This question is part of the following fields:
- Dermatology
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Question 5
Correct
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A 16-year-old male visits the nearby sexual health clinic with a concern. He has a sizable, keratinised genital wart on the shaft of his penis that has been there for approximately three months. Due to embarrassment, he has delayed seeking medical attention. What is the best initial course of action?
Your Answer: Cryotherapy
Explanation:For the treatment of genital warts, cryotherapy is recommended for solitary, keratinised warts, while topical podophyllum is suggested for multiple, non-keratinised warts. As the wart is keratinised, cryotherapy should be the first choice of treatment.
Understanding Genital Warts
Genital warts, also known as condylomata accuminata, are a common reason for visits to genitourinary clinics. These warts are caused by various types of the human papillomavirus (HPV), with types 6 and 11 being the most common. It is important to note that HPV, particularly types 16, 18, and 33, can increase the risk of cervical cancer.
The warts themselves are small, fleshy growths that are typically 2-5 mm in size and may be slightly pigmented. They can also cause itching or bleeding. Treatment options for genital warts include topical podophyllum or cryotherapy, depending on the location and type of lesion. Topical agents are generally used for multiple, non-keratinised warts, while solitary, keratinised warts respond better to cryotherapy. Imiquimod, a topical cream, is typically used as a second-line treatment. It is important to note that genital warts can be resistant to treatment, and recurrence is common. However, most anogenital HPV infections clear up on their own within 1-2 years without intervention.
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This question is part of the following fields:
- Dermatology
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Question 6
Correct
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A 40-year-old man presents to the General Practitioner (GP) with a scaly erythematous rash on his right foot. There is no rash on his left foot. The GP suspects a dermatophyte fungal infection (Tinea pedis) and wants to confirm the diagnosis.
What is the correct statement about the skin scraping specimen?Your Answer: The presence of branching hyphae on microscopy confirms the diagnosis
Explanation:Diagnosing Fungal Skin Infections: Microscopy and Culture
To confirm a dermatophyte fungal infection, skin samples are collected for microscopy and culture. A scalpel blade is used to scrape off superficial scales from the leading edge of the rash. Lack of scale may indicate a misdiagnosis. Microscopy involves staining the sample with potassium hydroxide and examining it for fungal hyphae. Culture identifies the specific organism responsible for the infection, but may take several weeks and can produce false negatives. Yeast infections can be identified by seeing budding yeast cells under the microscope, but yeasts and moulds may also be harmless colonizers. It is important to confirm the diagnosis before treatment, but if a dermatophyte infection is suspected, treatment should begin promptly. Samples should be transported in a sterile container or black paper envelope.
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This question is part of the following fields:
- Dermatology
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Question 7
Incorrect
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A seven-year-old boy comes to the GP with his mother, who reports a persistent eczema patch on his right cheek that has worsened despite his regular use of emollient and topical hydrocortisone treatment. The patch has become excruciatingly painful overnight and has spread to his chin. The boy has had eczema since he was a baby but is otherwise healthy.
During the examination, the GP observes a dry, reddish skin patch on the right cheek and a larger, more inflamed patch on the left that extends to the chin. The area is warm and tender to the touch. The patient's vital signs are normal.
What is the most appropriate course of action?Your Answer:
Correct Answer: Same-day referral to paediatrics
Explanation:When a child presents with rapidly worsening and painful eczema that is not responding to usual treatment, it may be an early sign of eczema herpeticum. This is a medical emergency that requires urgent assessment and treatment with antivirals to prevent systemic complications. Therefore, the most appropriate action is same-day referral to paediatrics. Oral aciclovir, oral flucloxacillin, and topical clobetasol are not the most appropriate actions in this case. Mild cases may respond to oral antivirals, but a thorough assessment is necessary, and IV antiviral treatment may be required for facial involvement. Definitive treatment for eczema herpeticum is antivirals, not antibiotics or topical steroids.
Eczema herpeticum is a serious skin infection caused by herpes simplex virus 1 or 2. It is commonly observed in children who have atopic eczema and is characterized by a rapidly progressing painful rash. The affected area usually shows monomorphic punched-out erosions, which are circular, depressed, and ulcerated lesions with a diameter of 1-3 mm.
Due to its life-threatening potential, children with eczema herpeticum should be admitted for intravenous aciclovir treatment.
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This question is part of the following fields:
- Dermatology
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Question 8
Incorrect
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A 35-year-old female patient comes to you with circular patches of non-scarring hair loss on her scalp that have developed in the last 3 months. You diagnose her with alopecia areata. Although you suggest a watch-and-wait approach, she is distressed by the condition and wishes to try treatment. What management options could you initiate in Primary Care?
Your Answer:
Correct Answer: Topical steroid
Explanation:Patients with hair loss may experience natural recovery within a year, but those who do not see regrowth or have more than 50% hair loss may require further treatment.
Understanding Alopecia Areata
Alopecia areata is a condition that is believed to be caused by an autoimmune response, resulting in localized hair loss that is well-defined and demarcated. This condition is characterized by the presence of small, broken hairs that resemble exclamation marks at the edge of the hair loss. While hair regrowth occurs in about 50% of patients within a year, it eventually occurs in 80-90% of patients. In many cases, a careful explanation of the condition is sufficient for patients. However, there are several treatment options available, including topical or intralesional corticosteroids, topical minoxidil, phototherapy, dithranol, contact immunotherapy, and wigs. It is important to understand the causes and treatment options for alopecia areata to effectively manage this condition.
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This question is part of the following fields:
- Dermatology
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Question 9
Incorrect
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A 32-year-old man with a history of atopic eczema and contact dermatitis experiences worsening of his dermatitis due to irritants at work. What is the most frequent irritant that leads to contact dermatitis?
Your Answer:
Correct Answer: Soap and cleaning agents
Explanation:Common Causes of Contact Dermatitis
Contact dermatitis is a skin condition that occurs when the skin comes into contact with an irritant or allergen. The most common causes of contact dermatitis include soap and cleaning agents, which can affect people in various fields, especially cleaners and healthcare workers. Wet work is also a significant cause of dermatitis. Latex, particularly in the form of latex-powdered gloves, used to be a common irritant, but the use of latex-free gloves has reduced its occurrence. Nickel found in jewelry can cause a localized reaction, but it is less common than dermatitis caused by soap and cleaning products. Acrylics can also cause contact dermatitis, but they are less common than other irritants. Natural fibers like cotton are less likely to cause a dermatitis reaction compared to synthetic fibers.
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This question is part of the following fields:
- Dermatology
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Question 10
Incorrect
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A 27-year-old male presents with irregular skin discoloration on his upper back after returning from a 2-week vacation in Ibiza. Although he applied sunscreen intermittently, he did experience mild sunburn in the area, which has since healed. He doesn't experience any pain or itching, but he is self-conscious about the appearance of his skin. During the examination, there are scattered pale pink macules covered with fine scales visible over his upper back, despite having a suntan. What is the most probable diagnosis?
Your Answer:
Correct Answer: Pityriasis versicolor
Explanation:The patient has pityriasis Versicolor, a fungal infection that affects sebum-rich areas of skin. It presents as multiple round or oval macules that may coalesce, with light pink, red or brown colour and fine scale. Itching is mild. It is not vitiligo, sunburn or pityriasis rosea, nor tinea corporis.
Understanding Pityriasis Versicolor
Pityriasis versicolor, also known as tinea versicolor, is a fungal infection that affects the skin’s surface. It is caused by Malassezia furfur, which was previously known as Pityrosporum ovale. This condition is characterized by patches that are commonly found on the trunk area. These patches may appear hypopigmented, pink, or brown, and may become more noticeable after sun exposure. Scaling is also a common feature, and mild itching may occur.
Pityriasis versicolor can affect healthy individuals, but it may also occur in people with weakened immune systems, malnutrition, or Cushing’s syndrome. Treatment for this condition typically involves the use of topical antifungal agents. According to NICE Clinical Knowledge Summaries, ketoconazole shampoo is a cost-effective option for treating large areas. If topical treatment fails, alternative diagnoses should be considered, and oral itraconazole may be prescribed.
In summary, pityriasis versicolor is a fungal infection that affects the skin’s surface. It is characterized by patches that may appear hypopigmented, pink, or brown, and scaling is a common feature. Treatment typically involves the use of topical antifungal agents, and oral itraconazole may be prescribed if topical treatment fails.
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This question is part of the following fields:
- Dermatology
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