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Question 1
Incorrect
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A diabetic woman attends for an ultrasound scan during her third trimester of pregnancy. The physician reporting the scan calculates an amniotic index >95th centile and diagnoses polyhydramnios.
What volume of amniotic fluid is considered to be consistent with polyhydramnios?Your Answer: >4–5 l of amniotic fluid
Correct Answer: >2–3 l of amniotic fluid
Explanation:Understanding Polyhydramnios: Excess Amniotic Fluid in Pregnancy
Polyhydramnios is a condition in which there is an excess of amniotic fluid in the second and third trimesters of pregnancy. This excess fluid is produced by the fetal kidneys and is normally swallowed by the fetus. Diagnosis of polyhydramnios is made by ultrasound assessment of the amount of fluid. If the deepest vertical pool is greater than 8 cm or if the amniotic fluid index (AFI) is greater than the 95th percentile for the corresponding gestational age, polyhydramnios is diagnosed.
Polyhydramnios occurs in approximately 2% of all pregnancies and is associated with maternal diabetes and fetal anomalies resulting in gastrointestinal obstruction, such as esophageal atresia and poor fetal swallowing.
It is important to note that normal amniotic fluid varies and increases with gestational age, peaking at around 1 liter. An excess of 2 liters or more is considered consistent with polyhydramnios. Understanding this condition can help healthcare providers monitor and manage pregnancies for the best possible outcomes.
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This question is part of the following fields:
- Obstetrics
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Question 2
Incorrect
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A 67-year-old man attends for his first abdominal aortic aneurysm screening. He is found to have an asymptomatic abdominal aortic aneurysm measuring 5.3 cm. He is seen routinely by a regional vascular centre that made the decision not to perform an elective repair. He has been advised to stop smoking, reduce his blood pressure through antihypertensive medications and to attend surveillance appointments.
How often should the patient receive surveillance abdominal ultrasounds?Your Answer:
Correct Answer: Every three months
Explanation:Surveillance Frequency for Abdominal Aneurysms
Abdominal aneurysms require regular surveillance to monitor their growth and determine if intervention is necessary. The frequency of surveillance depends on the size of the aneurysm.
For an aneurysm between 4.5 and 5.4 cm, surveillance should be offered every three months. If the aneurysm is 3.0–4.4 cm, aortic ultrasound should be performed every twelve months. Aneurysms greater than 5.5 cm in diameter are invariably repaired.
Aneurysms are repaired if they are symptomatic, asymptomatic and 5.5 cm or larger, or larger than 4.0 cm and growing by more than 1.0 cm in the preceding 12 months.
It is important to follow the recommended surveillance frequency to ensure timely intervention and prevent complications.
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This question is part of the following fields:
- Statistics
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Question 3
Incorrect
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A 50-year-old woman presents with fatigue, weight gain and constipation. On examination, she has cool and dry hands, bradycardia and slow-relaxing reflexes. When asked about medication, she reports taking a tablet for her mental health disorder for a prolonged period. Which medication is most likely responsible for her current symptoms?
Your Answer:
Correct Answer: Lithium
Explanation:Lithium and Hypothyroidism
Lithium is a commonly used medication for bipolar disorder, but it has a narrow therapeutic window and can easily cause toxicity. One of the long-term side effects of lithium is hypothyroidism, which can present with symptoms such as cool hands, bradycardia, and slow reflexes. Treatment for hypothyroidism caused by lithium typically involves thyroxine. Other psychiatric medications, such as olanzapine, amitriptyline, clonazepam, and clozapine, are less likely to cause hypothyroidism and would not present with the same clinical picture.
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This question is part of the following fields:
- Pharmacology
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Question 4
Incorrect
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A 78-year-old man experiences a sensation of something ‘giving way’ in his right arm while lifting a heavy bag of garden waste. The arm is visibly bruised, and upon flexing the elbow, a lump appears in the middle of the anterior aspect of the arm. The diagnosis is a rupture of the tendon of the long head of the biceps brachii. Where does this tendon typically attach to a bony point?
Your Answer:
Correct Answer: Supraglenoid tubercle of the scapula
Explanation:The supraglenoid tubercle of the scapula is where the tendon of the long head of the biceps brachii attaches within the shoulder joint capsule. The lesser tuberosity of the humerus is where the subscapularis muscle inserts, while the crest of the lesser tuberosity is where the latissimus dorsi and teres major muscles attach. The coracoid process of the scapula is where the short head of the biceps brachii, coracobrachialis, and pectoralis minor muscles attach. The greater tuberosity of the humerus is where the supraspinatus, infraspinatus, and teres minor muscles insert. Lastly, the long head of the triceps brachii attaches to the infraglenoid tubercle of the scapula. These attachments and insertions are important for understanding the anatomy and function of the shoulder and arm muscles.
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This question is part of the following fields:
- Orthopaedics
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Question 5
Incorrect
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You are called to see an 80-year-old man who was admitted for an anterior resection for sigmoid cancer. His operation was uncomplicated, and he is now three days post operation. He has hypercholesterolaemia and hypertension, but was otherwise fit before diagnosis. You find that the man is in atrial fibrillation. Nursing staff report that he is increasingly confused and appears to be in pain despite postoperative pain relief. They also report decreased urine output and tachycardia when they last took observations.
What is the most likely cause of these symptoms?Your Answer:
Correct Answer: Anastomotic leak
Explanation:Differential Diagnosis for a Patient with Signs of Sepsis Post-Abdominal Surgery
When a patient presents with signs of sepsis post-abdominal surgery, it is important to consider the possible causes. While anastomotic leak is a common complication, hospital-acquired pneumonia, consequences of surgery, pulmonary embolus, and pre-existing cardiac conditions can also be potential factors. However, it is crucial to note that each condition presents with distinct symptoms and signs. Therefore, a thorough evaluation and investigation are necessary to determine the underlying cause and provide appropriate treatment.
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This question is part of the following fields:
- Colorectal
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Question 6
Incorrect
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A 50-year-old male presents with sudden onset of severe headache accompanied by vomiting and photophobia. Upon examination, the patient appears distressed with a temperature of 37.5°C and a Glasgow coma scale of 15/15. His blood pressure is 146/88 mmHg. The patient exhibits marked neck stiffness and photophobia, but neurological examination is otherwise normal. What is the suspected diagnosis?
Your Answer:
Correct Answer: Subarachnoid haemorrhage
Explanation:Subarachnoid Haemorrhage: Symptoms, Complications, and Diagnosis
Subarachnoid haemorrhage (SAH) is a medical emergency that presents with a sudden and severe headache accompanied by meningeal irritation. Patients may also experience a slightly elevated temperature and localising signs with larger bleeds. Other symptoms include neurogenic pulmonary oedema and ST segment elevation on the ECG. Complications of SAH include recurrent bleeding, vasospasm, and stroke. Delayed complications may also arise, such as hydrocephalus due to the presence of blood in the cerebrospinal fluid (CSF).
Imaging may not always detect the bleed, especially if it is small. Therefore, CSF analysis is crucial in suspected cases, with the presence of red blood cells confirming the diagnosis. It is important to seek immediate medical attention if SAH is suspected, as prompt diagnosis and treatment can improve outcomes.
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This question is part of the following fields:
- Emergency Medicine
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Question 7
Incorrect
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You are a junior doctor in paediatrica and have been asked to perform a newborn exam. Which statement is true regarding the Barlow and Ortolani manoeuvres?
Your Answer:
Correct Answer: It relocates a dislocation of the hip joint if this has been elicited during the Barlow manoeuvre
Explanation:Understanding the Barlow and Ortolani Manoeuvres for Hip Dislocation Screening
Hip dislocation is a common problem in infants, and early detection is crucial for successful treatment. Two screening tests commonly used are the Barlow and Ortolani manoeuvres. The Barlow manoeuvre involves adducting the hip while applying pressure on the knee, while the Ortolani manoeuvre flexes the hips and knees to 90 degrees, with pressure applied to the greater trochanters and thumbs to abduct the legs. A positive test confirms hip dislocation, and further investigation is necessary if risk factors are present, such as breech delivery or a family history of hip problems. However, a negative test does not exclude all hip problems, and parents should seek medical advice if they notice any asymmetry or walking difficulties in their child.
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This question is part of the following fields:
- Paediatrics
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Question 8
Incorrect
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A 52-year-old man with a history of chronic obstructive pulmonary disease (COPD) presents to the Emergency Department with an acute exacerbation. He is experiencing severe shortness of breath and his oxygen saturation levels are at 74% on room air. The medical team initiates treatment with 15 litres of high-flow oxygen and later transitions him to controlled oxygen supplementation via a 28% venturi mask. What is the optimal target range for his oxygen saturation levels?
Your Answer:
Correct Answer: 88–92%
Explanation:Understanding Oxygen Saturation Targets for Patients with COPD
Patients with COPD have specific oxygen saturation targets that differ from those without respiratory problems. The correct range for a COPD patient is 88-92%, as they rely on low oxygen concentrations to drive their respiratory effort. Giving them too much oxygen can potentially remove their drive to breathe and worsen their respiratory situation. In contrast, unwell individuals who are not at risk of type 2 respiratory failure have a target of 94-98%. A saturation target of 80% is too low and can cause hypoxia and damage to end organs. Saturations of 90-94% may indicate a need for oxygen therapy, but it may still be too high for a patient with COPD. It is vital to obtain an arterial blood gas (ABG) in hypoxia to check if the patient is a chronic CO2 retainer. Understanding these targets is crucial in managing patients with COPD and ensuring their respiratory effort is not compromised.
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This question is part of the following fields:
- Respiratory
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Question 9
Incorrect
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A 19-year-old male has recently been diagnosed with schizophrenia. He was prescribed haloperidol, but after two weeks, he was discovered to be confused and drowsy. Upon examination, he was found to have a fever of 40.7°C, rigid muscles, and a blood pressure of 200/100 mmHg. What treatment would you recommend in this situation?
Your Answer:
Correct Answer: Dantrolene
Explanation:Neuroleptic Malignant Syndrome
Neuroleptic malignant syndrome (NMS) is a serious medical condition that is commonly caused by potent neuroleptics. Its major features include rigidity, altered mental state, autonomic dysfunction, fever, and high creatinine kinase. The condition can lead to potential complications such as rhabdomyolysis and acute renal failure.
The treatment of choice for NMS is dantrolene and bromocriptine. However, withdrawal of neuroleptic treatment is mandatory to prevent further complications. It is important to note that NMS can be life-threatening and requires immediate medical attention. Therefore, it is crucial to recognize the symptoms and seek medical help as soon as possible.
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This question is part of the following fields:
- Neurology
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Question 10
Incorrect
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A 25-year-old woman visits her doctor seeking advice on contraception. After being informed about all available methods, she chooses a copper IUD. A pregnancy test conducted at the clinic comes back negative. She has a consistent 28-day menstrual cycle. During which phase of her cycle can the IUD be inserted?
Your Answer:
Correct Answer: Anytime during cycle
Explanation:The copper IUD is suitable for fitting at any stage of the menstrual cycle. It can also be fitted right after a first or second-trimester abortion, as well as 4 weeks after giving birth. It is crucial to advise the patient to avoid sexual intercourse or use effective contraception until the IUD is in place to prevent pregnancy.
Intrauterine contraceptive devices include copper IUDs and levonorgestrel-releasing IUS. Both are over 99% effective. The IUD prevents fertilization by decreasing sperm motility, while the IUS prevents endometrial proliferation and thickens cervical mucous. Potential problems include heavier periods with IUDs and initial bleeding with the IUS. There is a small risk of uterine perforation, ectopic pregnancy, and infection. New IUS systems, such as Jaydess® and Kyleena®, have smaller frames and less levonorgestrel, resulting in lower serum levels and different rates of amenorrhea.
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This question is part of the following fields:
- Gynaecology
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Question 11
Incorrect
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A 48-year-old man presents to the emergency department after a bicycle accident. He reports feeling fine and denies any symptoms such as vomiting, seizures, or loss of consciousness. The patient has a medical history of tricuspid valve replacement and takes warfarin. On examination, a small 1 cm laceration is found on his left temple, which has stopped bleeding. The patient has a GCS score of 15/15 and a normal neurological exam. What is the best course of action?
Your Answer:
Correct Answer: Perform a CT scan within 8 hours
Explanation:If a person is taking anticoagulants and has suffered a head injury, it is crucial to conduct a CT scan within 8 hours. This is because such patients are at a higher risk of developing intracranial bleeds, which may have a delayed onset of symptoms. While neurological observations are necessary, they cannot replace the need for a CT scan in this case. Discharging the patient with safety netting advice would also be inappropriate as they may have developed a serious intracranial bleed due to their anticoagulant therapy. However, performing a CT scan within 1 hour is not necessary if the patient does not exhibit key symptoms such as post-traumatic seizures or vomiting. It is also not appropriate to perform an MRI scan within 8 hours as CT scan is the preferred imaging modality for head injuries.
NICE Guidelines for Investigating Head Injuries in Adults
Head injuries can be serious and require prompt medical attention. The National Institute for Health and Care Excellence (NICE) has provided clear guidelines for healthcare professionals to determine which adult patients need further investigation with a CT head scan. Patients who require immediate CT head scans include those with a Glasgow Coma Scale (GCS) score of less than 13 on initial assessment, suspected open or depressed skull fractures, signs of basal skull fractures, post-traumatic seizures, focal neurological deficits, and more than one episode of vomiting.
For patients with any loss of consciousness or amnesia since the injury, a CT head scan within 8 hours is recommended for those who are 65 years or older, have a history of bleeding or clotting disorders, experienced a dangerous mechanism of injury, or have more than 30 minutes of retrograde amnesia of events immediately before the head injury. Additionally, patients on warfarin who have sustained a head injury without other indications for a CT head scan should also receive a scan within 8 hours of the injury.
It is important for healthcare professionals to follow these guidelines to ensure that patients receive appropriate and timely care for their head injuries. By identifying those who require further investigation, healthcare professionals can provide the necessary treatment and support to prevent further complications and improve patient outcomes.
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This question is part of the following fields:
- Surgery
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Question 12
Incorrect
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A 54-year-old male with a history of cirrhosis due to alcohol abuse presents with malaise and decreased urine output. Upon examination, he appears jaundiced and his catheterized urine output is only 5 ml per hour. Laboratory results show low urinary sodium and elevated urine osmolality compared to serum osmolality. Blood tests reveal elevated liver enzymes, bilirubin, and creatinine. What is the probable diagnosis?
Your Answer:
Correct Answer: Hepatorenal syndrome
Explanation:Hepatorenal Syndrome
Hepatorenal syndrome is a severe medical condition that can lead to the rapid deterioration of kidney function in individuals with cirrhosis or fulminant hepatic failure. This condition occurs due to changes in the circulation that supplies the intestines, which alters the blood flow and tone in vessels supplying the kidney. As a result, the liver’s deranged function causes Hepatorenal syndrome, which can be life-threatening. Unfortunately, the only treatment for this condition is liver transplantation.
While hepatitis B can present as membranous glomerulonephritis, it is unlikely in this case due to the known history of alcoholic liver disease. Acute tubular necrosis is also possible, which can result from toxic medication and reduced blood pressure to the kidney in individuals with cirrhosis. However, in acute tubular necrosis, urine and sodium osmolality are raised compared to Hepatorenal syndrome, where the urine and serum sodium osmolality are low. Additionally, one would expect to see muddy-brown casts or hyaline casts on urine microscopy in someone with acute tubular necrosis.
In conclusion, Hepatorenal syndrome is crucial for individuals with cirrhosis or fulminant hepatic failure. This condition can lead to the rapid deterioration of kidney function and can be life-threatening. While other conditions such as hepatitis B and acute tubular necrosis can present similarly, they have distinct differences that can help with diagnosis and treatment.
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This question is part of the following fields:
- Gastroenterology
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Question 13
Incorrect
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A 25-year-old man is brought to the Emergency department by his friends after being found on the floor following a night out. There are suspicions that he may have taken drugs, although the exact substance is unknown. Upon examination, he is found to be semi-conscious with a rapid respiratory rate. A catheterisation procedure yields 25 mls of dark brown coloured urine which tests positive for haemoglobin using urinalysis.
What potential blood and electrolyte imbalances should be anticipated in this patient?Your Answer:
Correct Answer: Hyperuricaemia with acidosis
Explanation:Rhabdomyolysis: Symptoms and Treatment
Rhabdomyolysis is a medical condition that occurs when there is a rapid breakdown of skeletal muscle. This condition is associated with several biochemical abnormalities, including elevated levels of creatine kinase (CK), potassium, urate, and myoglobinuria. Additionally, calcium levels may be elevated intracellularly in myocytes, but normal or low in the blood during the early stages of the disease. However, as the disease progresses, calcium levels in the blood may increase. Acidosis is also a common symptom of rhabdomyolysis.
Early and aggressive treatment is crucial in managing rhabdomyolysis. Rehydration and managing hyperkalemia can help reduce the likelihood of developing complications such as arrhythmias due to electrolyte disturbance, renal failure, disseminated intravascular coagulation, and compartment syndrome. By the symptoms and seeking prompt medical attention, individuals with rhabdomyolysis can receive the necessary treatment to manage the condition and prevent further complications.
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This question is part of the following fields:
- Nephrology
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Question 14
Incorrect
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A screening test for a disease is performed on 1000 people over the age of 50. A total of 888 people do not have the disease. Of those with the disease, 100 had a positive screening test result. A total of 890 patients had a negative screening test result.
What is the specificity of the screening test?Your Answer:
Correct Answer: 98.90%
Explanation:Understanding the Different Values in Screening Test Results
Screening tests are important in identifying potential health issues in individuals. However, it is important to understand the different values that come with screening test results. One of these values is specificity, which identifies the percentage of patients correctly identified as not having the condition. Sensitivity, positive predictive value, negative predictive value, and disease specificity are also important values to consider. By placing the numbers into a table and using specific equations, these values can be calculated and used to better understand screening test results.
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This question is part of the following fields:
- Statistics
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Question 15
Incorrect
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A 60-year-old bus driver is referred by his general practitioner with a change in bowel habit and bleeding per rectum. He reports no further symptoms, and an abdominal and digital rectal examination are unremarkable. However, colonoscopy shows a high rectal tumour, encompassing approximately two-thirds of the diameter of the colon. He is booked to have an operation.
Which of the following is he most likely to be listed for?Your Answer:
Correct Answer: Anterior resection
Explanation:Types of Colorectal Resection Surgeries
Colorectal resection surgeries are performed to remove cancerous or non-cancerous tumors in the colon or rectum. Here are the different types of colorectal resection surgeries:
1. Anterior Resection: This surgery is recommended for non-obstructed tumors in the distal sigmoid colon, middle or upper rectum.
2. abdominoperineal Resection: This surgery is used for operable low rectal and anorectal tumors. It involves the removal of the anus, rectum, and sigmoid colon, and the formation of an end-colostomy.
3. Sigmoid Colectomy: This surgery is used for operable tumors in the sigmoid colon.
4. Left Hemicolectomy: This surgery is used for operable tumors in the descending colon.
5. Pan-colectomy: This surgery involves the removal of the entire colon and is typically performed in cases of ulcerative colitis. It requires the formation of a permanent ileostomy or the construction of an ileal-anal pouch.
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This question is part of the following fields:
- Colorectal
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Question 16
Incorrect
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A 67-year-old woman is on the surgical ward after admission for neurological observations following a head injury. She had fallen on the pavement and banged her head with a moderate laceration. She suffered from no loss of consciousness but now complains of nausea and double vision. You notice that:
her eyes open to speech
she is able to obey commands
she can talk properly but appears disorientated in time and place.
What is her Glasgow Coma Scale (GCS) score?Your Answer:
Correct Answer: 13
Explanation:Understanding the Glasgow Coma Scale
The Glasgow Coma Scale (GCS) is a valuable tool for assessing a patient’s level of consciousness, particularly in cases of head injury. It provides a standardized language for clinicians to communicate about a patient’s condition. The GCS measures the best eye, verbal, and motor responses and calculates a total score. A fully conscious and alert patient will score 15/15, while the lowest possible score is 3/15.
The GCS score is calculated based on the patient’s eye, verbal, and motor responses. The eyes can open spontaneously, in response to speech or pain, or not at all. The verbal response can range from being oriented to being completely unresponsive. The motor response can range from obeying commands to abnormal flexion or no response at all.
It is important to note that if a patient’s GCS score is 8 or below, they will require airway protection as they will be unable to protect their own airway. This typically means intubation. It is crucial to accurately calculate the GCS score to ensure appropriate medical intervention.
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This question is part of the following fields:
- Neurosurgery
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Question 17
Incorrect
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A 65-year-old patient arrives at the emergency department with complaints of abdominal pain and distention. They have not had a bowel movement in 4 days and have not passed gas in 1 day. During the examination, hyperactive bowel sounds are heard, and a digital rectal exam reveals an empty rectum. An urgent CT scan of the abdomen and pelvis with contrast reveals a suspicious large localized lesion in the descending colon, causing bowel obstruction and severely dilated bowel loops.
What is the most appropriate initial surgical option for this patient?Your Answer:
Correct Answer: Loop colostomy
Explanation:The preferred surgical procedure for obstructing cancers in the distal colon is a loop colostomy. This involves creating a stoma with two openings, one connected to the functioning part of the bowel and the other leading into the distal colon to dysfunction and decompress it. The stoma can be reversed at a later time. However, other procedures such as AP resection, ileocolic anastomosis, and ileostomy are not appropriate for this patient’s descending colon mass.
Abdominal stomas are created during various abdominal procedures to bring the lumen or contents of organs onto the skin. Typically, this involves the bowel, but other organs may also be diverted if necessary. The type and method of construction of the stoma will depend on the contents of the bowel. Small bowel stomas should be spouted to prevent irritant contents from coming into contact with the skin, while colonic stomas do not require spouting. Proper siting of the stoma is crucial to reduce the risk of leakage and subsequent maceration of the surrounding skin. The type and location of the stoma will vary depending on the purpose, such as defunctioning the colon or providing feeding access. Overall, abdominal stomas are a necessary medical intervention that requires careful consideration and planning.
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This question is part of the following fields:
- Surgery
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Question 18
Incorrect
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A 25-year-old law student complains that she cannot fall asleep until 0330 h. She sleeps through morning classes, frequently waking up at about 1100 h.
What is the most likely diagnosis?Your Answer:
Correct Answer: Delayed sleep phase syndrome
Explanation:Common Sleep Disorders and Their Symptoms
Sleep disorders can have a significant impact on a person’s quality of life. Here are some of the most common sleep disorders and their symptoms:
1. Delayed Sleep Phase Syndrome: This syndrome causes a person’s circadian cycle to run longer than 24 hours, leading to a tendency to fall asleep later and later.
2. Advanced Sleep Phase Syndrome: Patients with this syndrome tend to fall asleep too early and wake up too early.
3. Myoclonus: Nocturnal myoclonus, or periodic limb movement disorder, causes twitching or kicking of the lower extremities during sleep, leading to momentary arousals.
4. Narcolepsy: This dyssomnia causes a person to suddenly fall asleep involuntarily at inappropriate times.
5. Sleep Apnoea: This disorder causes a person to stop breathing during sleep, putting stress on the circulatory system.
It’s important to seek medical attention if you suspect you have a sleep disorder.
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This question is part of the following fields:
- Neurology
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Question 19
Incorrect
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A 42-year-old man presents to his General Practitioner with a 6-month history of erectile dysfunction. He also reports that he has noticed galactorrhoea and is experiencing headaches, usually upon waking in the morning. He has no significant past medical history. His blood test results are as follows:
Investigation(s) Result Normal range
Haemoglobin (Hb) 142 g/l 130–180 g/l
White cell count (WCC) 5.0 × 109/l 3.5–11 × 109/l
Sodium (Na+) 138 mmol/l 135–145 mmol/l
Potassium (K+) 4.1 mmol/l 3.5–5.3 mmol/l
Thyroid-stimulating hormone (TSH) 3.8 mU/l 0.27-4.2 mU/l
Prolactin 5234 mU/l 86-324 mU/l
Which of the following further investigations should be requested?Your Answer:
Correct Answer: Magnetic resonance imaging (MRI) pituitary
Explanation:For a patient with symptoms and blood tests indicating prolactinaemia, further tests are needed to measure other pituitary hormones. An MRI scan of the pituitary gland is necessary to diagnose a macroprolactinoma, which is likely due to significantly elevated prolactin levels and early-morning headaches. A CT of the adrenal glands is useful in diagnosing phaeochromocytoma, which presents with symptoms such as headaches, sweating, tachycardia, hypertension, nausea and vomiting, anxiety, and tremors. A 24-hour urinary 5HIAA test is used to diagnose a serotonin-secreting carcinoid tumor, which presents with symptoms such as flushing, diarrhea, and tachycardia. A chest X-ray is not useful in diagnosing a prolactinoma, which is an adenoma of the pituitary gland. For imaging of prolactinomas, MRI is the preferred method as it is more sensitive in detecting small tumors (microprolactinomas).
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This question is part of the following fields:
- Urology
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Question 20
Incorrect
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A 35-year-old male is brought into the emergency department unconscious after a motorcycle accident. He was the rider of the motorcycle and there is suspicion that he was under the influence of drugs at the time of the accident. His girlfriend is present and unharmed. The police are requesting a blood sample for drug testing, but the patient is unable to provide consent and there is no forensic physician available. As a healthcare worker in the emergency department, what is the appropriate course of action in this situation?
Your Answer:
Correct Answer: Draw a blood sample for later analysis when the patient is competent to consent
Explanation:The BMA has provided guidance on taking blood specimens from incapacitated drivers. The law allows for a blood specimen to be taken without consent if a police constable believes the person is incapable of giving valid consent due to medical reasons. A forensic physician or another doctor must take the sample, and the doctor in charge of the patient’s care must be notified beforehand. The specimen cannot be tested until the person regains competence and gives valid consent. Refusal to allow testing may result in prosecution. The new law recognizes the duty to justice.
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This question is part of the following fields:
- Miscellaneous
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Question 21
Incorrect
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A 20-year-old man presents to his doctor with a yellowish tinge to his skin and eyes and a tremor in his right hand. He mentions that his family has noticed a change in his speech and have been teasing him about sounding drunk. Upon examination, the doctor notes the presence of hepatomegaly, Kayser-Fleischer rings, and the tremor. What is the probable reason for the man's jaundice?
Your Answer:
Correct Answer: Wilson’s disease
Explanation:Common Liver Disorders and Their Characteristics
Wilson’s Disease: A rare genetic disorder that results in copper deposition in various organs, including the liver, cornea, and basal ganglia of the brain. It typically presents in children with hepatic problems and young adults with neurological symptoms such as dysarthria, tremor, involuntary movements, and eventual dementia. Kayser-Fleischer rings may be present.
Alpha-1-Antitrypsin Deficiency: A genetic disorder that results in severe deficiency of A1AT, a protein that inhibits enzymes from inflammatory cells. This can lead to cirrhosis, but is typically associated with respiratory pathology and does not present with Kayser-Fleischer rings.
Haemochromatosis: A genetic disorder that results in iron overload and is typically described as bronze diabetes due to the bronzing of the skin and the common occurrence of diabetes mellitus in up to 80% of patients.
Primary Biliary Cholangitis: An autoimmune condition that typically presents in middle-aged females with itching, jaundice, and Sjögren’s syndrome.
Autoimmune Hepatitis: An autoimmune disorder that often affects young and middle-aged women and is associated with other autoimmune disorders. Around 80% of patients respond well to steroids.
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This question is part of the following fields:
- Gastroenterology
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Question 22
Incorrect
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A cohort study of 5,000 elderly patients aimed to determine whether the consumption of green tea has an effect on cognitive decline. Roughly half of the patients drank green tea regularly and half did not.
What is a drawback of conducting a cohort study?Your Answer:
Correct Answer: When the outcome of interest is rare a very large sample size is needed
Explanation:Cohort Studies: Advantages and Disadvantages
A cohort study is a research method that involves following a group of individuals over a period of time to determine whether exposure to a particular factor has an effect on the incidence of disease. Although they are time-consuming and expensive, cohort studies have several advantages. For instance, they can be used to study rare exposure factors and are less prone to recall bias than case-control studies. Additionally, they can measure the incidence or risk of a disease, which is useful in determining the effectiveness of interventions.
One of the main advantages of cohort studies is that they allow researchers to study exposure factors that are rare. This is because they involve following a group of individuals over a period of time, which means that even if the exposure factor is rare, it may still be possible to observe its effects. Another advantage is that cohort studies are less susceptible to recall bias than case-control studies. This is because the exposure factor is measured before the disease occurs, which reduces the likelihood of participants misremembering their exposure.
However, cohort studies also have some disadvantages. One of the main disadvantages is that they are time-consuming and expensive to perform. This is because they involve following a group of individuals over a period of time, which requires a significant amount of resources. Additionally, cohort studies may not be suitable for studying diseases that have a long latency period, as it may take many years for the disease to develop. Finally, cohort studies may be affected by loss to follow-up, which can reduce the validity of the results.
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This question is part of the following fields:
- Clinical Sciences
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Question 23
Incorrect
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As a GP, you come across a 42-year-old man who had an incidental discovery of hyperlipidaemia during a recent insurance medical examination at work. His test results showed cholesterol levels of 22 mmol/L (ideal <5 mmol/L) with triglycerides of 18 mmol/L (<1.5 mmol/L). He is generally healthy but has low albumin and peripheral oedema. Upon conducting a urinalysis, the results are as follows:
Haemoglobin: Negative
Urobilinogen: Negative
Bilirubin: Negative
Protein: +++
Glucose: Negative
Nitrites: Negative
Leucocytes: Negative
Ketones: +
What could be the possible explanation for these findings?Your Answer:
Correct Answer: Nephrotic syndrome
Explanation:Nephrotic Syndrome
Nephrotic syndrome is a condition characterized by excessive protein loss in the urine, low levels of serum albumin, and peripheral edema. Patients with this condition often have severe hyperlipidemia, with total cholesterol levels exceeding 10 mmol/L. Additionally, the loss of natural anticoagulants in the urine can lead to altered clotting, which requires treatment with antiplatelet agents and/or low molecular weight heparin.
It is important to note that in the early stages of nephrotic syndrome, the levels of urea and creatinine may appear normal despite underlying renal pathology. Therefore, it is crucial to monitor patients with marked hyperlipidemia and proteinuria on urinalysis for signs of nephrotic syndrome. If diagnosed, patients should be referred to a local renal team for management.
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This question is part of the following fields:
- Nephrology
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Question 24
Incorrect
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A 3-month-old previously healthy boy is brought into the pediatrician's office by his father who is concerned about a change in his behavior. The father suspects his child has a fever. During the examination, the baby is found to have a temperature of 38.5 ºC but no other notable findings.
What should be the next course of action?Your Answer:
Correct Answer: Urgent referral for paediatric assessment at the hospital
Explanation:If a child under 3 months old has a fever above 38ºC, it is considered a high-risk situation and requires urgent assessment. This is a crucial factor to consider when evaluating a child with a fever. The NICE guidelines use a traffic light system to categorize the risk level of children under 5 with a fever, taking into account various factors such as the child’s appearance, activity level, respiratory function, circulation, hydration, and temperature. If the child falls under the green category, they can be managed at home with appropriate care advice. If they fall under the amber category, parents should be given advice and provided with a safety net, or the child should be referred for pediatric assessment. Children in the red category must be referred urgently to a pediatric specialist. In children under 3 months with fever, NICE recommends performing various investigations such as blood culture, full blood count, c-reactive protein, urine testing for urinary tract infections, stool culture if diarrhea is present, and chest x-ray if there are respiratory signs. Lumbar puncture should be performed in infants under 1 month old, all infants aged 1-3 months who appear unwell, and infants aged 1-3 months with a white blood cell count (WBC) less than 5 × 109/liter or greater than 15 × 109/liter. NICE also recommends administering parenteral antibiotics to this group of patients.
The NICE Feverish illness in children guidelines were introduced in 2007 and updated in 2013. These guidelines use a ‘traffic light’ system to assess the risk of children under 5 years old presenting with a fever. It is important to note that these guidelines only apply until a clinical diagnosis of the underlying condition has been made. When assessing a febrile child, their temperature, heart rate, respiratory rate, and capillary refill time should be recorded. Signs of dehydration should also be looked for. Measuring temperature should be done with an electronic thermometer in the axilla if the child is under 4 weeks old or with an electronic/chemical dot thermometer in the axilla or an infrared tympanic thermometer.
The risk stratification table includes green for low risk, amber for intermediate risk, and red for high risk. The table includes categories such as color, activity, respiratory, circulation and hydration, and other symptoms. If a child is categorized as green, they can be managed at home with appropriate care advice. If they are categorized as amber, parents should be provided with a safety net or referred to a pediatric specialist for further assessment. If a child is categorized as red, they should be urgently referred to a pediatric specialist. It is important to note that oral antibiotics should not be prescribed to children with fever without an apparent source, and a chest x-ray does not need to be routinely performed if a pneumonia is suspected but the child is not going to be referred to the hospital.
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This question is part of the following fields:
- Paediatrics
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Question 25
Incorrect
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A 24-hour-old neonate requires a detailed examination on the Postnatal Ward. It was a forceps delivery at 41+3 weeks’ gestation. The detailed examination is normal, except you notice slight reduced tone in the right leg and reduced Moro reflex on the right. The leg is resting in a slightly extended position. The examination is otherwise normal.
What is the most appropriate management?Your Answer:
Correct Answer: Refer to physiotherapy
Explanation:Assessing Erb’s Palsy in a Neonate: Appropriate Management and Investigations
Erb’s palsy is a neurological condition that commonly presents as reduced tone and movement in one arm, often due to shoulder dystocia during birth. In neonates, this can be identified by reduced Moro reflex and the arm resting in a waiter’s tip position. While Erb’s palsy is self-resolving, physiotherapy is recommended to strengthen the affected arm.
If there are no other neurological deficits, referral to a Paediatric Neurologist is not necessary. Cranial ultrasound and head MRI are also not appropriate investigations as they do not provide relevant information for this condition. Similarly, a shoulder X-ray is not necessary as the issue is neurological in nature. Overall, appropriate management and investigations for Erb’s palsy in a neonate involve physiotherapy and observation for resolution.
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This question is part of the following fields:
- Paediatrics
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Question 26
Incorrect
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A man in his late thirties has presented to the clinic with a complaint of numbness in the skin over his scrotum. Can you identify the nerve responsible for supplying sensation to this area?
Your Answer:
Correct Answer: Genital branch of the genitofemoral nerve
Explanation:Nerve Supply to Male Genitalia
The male genitalia are innervated by various nerves responsible for different functions. The genital branch of the genitofemoral nerve provides sensory nerve supply to the surface of the scrotum. On the other hand, the pudendal nerve, which gives rise to the dorsal nerve of the penis, is responsible for innervations of the bulbospongiosus and ischiocavernosus muscles, which are essential for erectile and ejaculatory functions.
However, the long course of the genitofemoral nerve, which includes travel through the superficial inguinal ring along with the spermatic cord, makes it susceptible to injury. Any damage to this nerve can result in sensory loss in the scrotum, leading to discomfort and pain.
The inferior anal and rectal nerve, which is also a branch of the pudendal nerve, provides sensory and motor innervation to the anal canal and rectum. These nerves play a crucial role in bowel and bladder control, and any damage to them can result in fecal and urinary incontinence.
In summary, the male genitalia are innervated by various nerves responsible for different functions, and any damage to these nerves can result in discomfort, pain, and loss of function. It is essential to understand the anatomy and function of these nerves to prevent injury and provide appropriate treatment in case of damage.
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This question is part of the following fields:
- Clinical Sciences
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Question 27
Incorrect
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A 50-year-old man with a history of hypertension, asthma and porphyria requires emergency surgery. His blood pressure and asthma are under control. What is the most suitable anaesthetic induction agent for the rapid sequence induction (RSI) procedure?
Your Answer:
Correct Answer: Propofol
Explanation:An Overview of Common Anaesthetic Induction Agents and Their Advantages and Adverse Effects
Propofol, ketamine, fentanyl, methohexital, and thiopental are commonly used anaesthetic induction agents. Propofol is the preferred choice for most people due to its rapid onset and offset of action, antiemetic and anticonvulsive effects, bronchodilation, and decreased cerebral metabolic oxygen demand and cerebral blood pressure. Ketamine is ideal for hypotensive patients due to its rapid onset, analgesic effects, bronchodilation, and maintenance of airway reflexes and respiratory drive. Fentanyl is an opiate analgesic used for pain relief, while methohexital is used for electroconvulsive therapy. Thiopental is a barbiturate used in general and regional anaesthesia. However, each agent has its own set of advantages and adverse effects that must be considered before use. For example, ketamine can increase intracranial pressure, cardiac output, and blood pressure, while thiopental can cause bronchoconstriction and is contraindicated in asthmatics and patients with a history of porphyria. It is important to carefully evaluate each patient’s medical history and condition before selecting an appropriate anaesthetic induction agent.
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This question is part of the following fields:
- Anaesthetics & ITU
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Question 28
Incorrect
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An 80-year-old woman has been suffering from Paget's disease of bone for over a decade. Lately, she has been experiencing increased pain in her lower back and hip region even when at rest. Upon conducting an X-ray, a destructive mass is observed in her bony pelvis. What is the probable diagnosis?
Your Answer:
Correct Answer: Osteosarcoma
Explanation:Paget’s Disease of Bone
Paget’s disease of bone is a condition that typically affects individuals in their later years. It is characterized by a disruption in the normal process of bone repair, resulting in the formation of weak bones that are prone to fractures. Specifically, the repair process ends at the stage of vascular osteoid bone, which is not as strong as fully mineralized bone.
Unfortunately, Paget’s disease of bone can also lead to complications such as osteogenic sarcoma, which occurs in approximately 5% of cases. As such, it is important for individuals with this condition to receive appropriate medical care and monitoring to prevent further complications.
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This question is part of the following fields:
- Oncology
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Question 29
Incorrect
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What is the primary nerve supply for the small muscles in the hand?
Your Answer:
Correct Answer: T1
Explanation:Innervation of Muscles in the Hand and Forearm
The muscles in the hand and forearm are controlled by different nerves depending on their location and function. The small muscles in the hand and forearm, such as the Flexor digitorum superficialis, Flexor pollicis longus, Flexor digitorum profundus, Lumbricals, and Interossei, are mainly innervated by the T1 nerve. This nerve controls the fine movements of the fingers and hand.
On the other hand, the larger muscles in the upper arm, such as the deltoids and biceps, are innervated by the C5 nerve. This nerve controls the movements of the shoulder and elbow joints. The extensors of the wrist are controlled by the C6 nerve, while the wrist extensors and triceps are controlled by the C7 nerve. Finally, the finger flexors of the hands are controlled by the C8 nerve.
the innervation of these muscles is important in diagnosing and treating injuries or conditions that affect the nerves in the upper extremities. By identifying which nerve is affected, healthcare professionals can develop a targeted treatment plan to help patients regain function and mobility in their hands and arms.
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This question is part of the following fields:
- Clinical Sciences
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Question 30
Incorrect
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A 42-year-old female smoker visits her GP seeking advice on contraception. She believes she has reached menopause as her last menstrual period was 15 months ago. What is the most suitable form of contraception for her?
The menopause is typically diagnosed retrospectively, 12 months after the last menstrual period. Women who experience menopause before the age of 50 require contraception for at least 2 years after their last menstrual period, while those over 50 require only 1 year of contraception. Given her age and smoking status, prescribing the combined oral contraceptive pill (COCP) for only 12 months would not be appropriate. Hormone replacement therapy (HRT) should not be used solely as a form of contraception, and barrier methods are less effective than other options. Therefore, the most suitable form of contraception for this patient would be the intrauterine system (IUS), which can be used for up to 7 years (off-licence) or 2 years after her last menstrual period.Your Answer:
Correct Answer: The intrauterine system (IUS)
Explanation:The menopause is diagnosed retrospectively and occurs 12 months after the last menstrual period. Women who experience menopause before the age of 50 need contraception for at least 2 years after their last menstrual period, while those over 50 require only 1 year of contraception. Therefore, it would be incorrect to assume that this woman does not need contraception because she is protected. Prescribing the COCP for only 12 months would also be inappropriate, especially since she is a smoker over the age of 35. Hormone replacement therapy should not be used as a sole form of contraception, and barrier methods are less effective than other types of contraception. The most appropriate option is the IUS, which can be used for 7 years (off-licence) or 2 years after her last menstrual period and will take her through menopause. This information is based on the FSRH’s guidelines on contraception for women aged over 40 (July 2010).
Understanding Menopause and Contraception
Menopause is a natural biological process that marks the end of a woman’s reproductive years. On average, women in the UK experience menopause at the age of 51. However, prior to menopause, women may experience a period known as the climacteric. During this time, ovarian function starts to decline, and women may experience symptoms such as hot flashes, mood swings, and vaginal dryness.
It is important for women to understand that they can still become pregnant during the climacteric period. Therefore, it is recommended to use effective contraception until a certain period of time has passed. Women over the age of 50 should use contraception for 12 months after their last period, while women under the age of 50 should use contraception for 24 months after their last period. By understanding menopause and the importance of contraception during the climacteric period, women can make informed decisions about their reproductive health.
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This question is part of the following fields:
- Gynaecology
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