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  • Question 1 - A 17-year-old male student spontaneously disrobed while watching a film. He saw wavy...

    Correct

    • A 17-year-old male student spontaneously disrobed while watching a film. He saw wavy lines on the screen and then reported a brief episode of mental blankness, followed soon after by a headache and extreme fatigue.
      What is the most likely diagnosis?

      Your Answer: Partial complex seizure or Focal Impaired Awareness epilepsy

      Explanation:

      Neuropsychiatric Syndromes and Seizure Disorders: Understanding the Differences

      Seizure disorders can be complex and varied, with different symptoms and causes. One type of seizure disorder is the partial complex seizure (PCS), which is confined to the limbic structures of the brain. Symptoms of PCS can include visual distortions and disruptions of cognitive function. Patients may also experience intense dysphoria, anxiety, or rage during or after a seizure. However, organised, directed violent behaviour is not typical of a seizure.

      Another type of seizure disorder is the generalised tonic-clonic epilepsy, which can cause a loss of consciousness and convulsions. Inhibition-type behaviour is not typical of this disorder, and there is no history of tonic-clonic seizure activity.

      Schizophreniform disorder is a condition that involves schizophrenic symptoms of short duration. Patients with repeated focal seizures may exhibit personality changes that closely resemble chronic schizophrenia, such as passivity, unusual sexual behaviour, anhedonia, obsessiveness, religiosity, and psychosis.

      Migraine behavioural syndrome can involve visual auras, but it is unlikely to involve bizarre behaviour such as inappropriate disrobing. Finally, exhibitionism involves attracting attention to oneself, such as compulsive exposure of genitals in public.

      Understanding the differences between these neuropsychiatric syndromes and seizure disorders is important for accurate diagnosis and treatment.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 2 - A 42-year-old woman presents to her GP with concerns about symptoms that have...

    Correct

    • A 42-year-old woman presents to her GP with concerns about symptoms that have been affecting her for several years but are now becoming more disruptive to her daily life. She has been experiencing obsessive thoughts about her loved ones being harmed and feels compelled to perform certain rituals to prevent this from happening. She spends hours each day checking and rechecking that appliances are turned off and doors are locked. Her relationships are suffering, and she is struggling to maintain her job. She is hesitant to take medication but is open to exploring other treatment options.
      What is the most appropriate psychological approach for managing OCD in this case?

      Your Answer: Exposure response prevention (ERP) and cognitive behavioural therapy (CBT)

      Explanation:

      Different Therapies for OCD: A Comparison

      Obsessive-compulsive disorder (OCD) is a mental health condition that can be managed with various therapies. The most effective ones are exposure response prevention (ERP) and cognitive behavioural therapy (CBT), which are recommended by the National Institute for Health and Care Excellence (NICE). ERP involves exposing the patient to situations that trigger their compulsive behaviour while preventing them from acting on it. CBT, on the other hand, focuses on changing the patient’s thoughts, beliefs, and attitudes that contribute to their OCD.

      Transactional analysis and psychoanalysis are not recommended for treating OCD as there is no evidence to support their use. Transactional analysis involves analysing social transactions to determine the ego state of the patient, while psychoanalysis involves exploring the unconscious to resolve underlying conflicts.

      Counselling is also not appropriate for managing OCD as it is non-directive and does not provide specific coping skills.

      Eye movement desensitisation and reprocessing (EMDR) is not effective for treating OCD either, as it is primarily used for post-traumatic stress disorder. EMDR combines rapid eye movement with cognitive tasks to help patients process traumatic experiences.

      In conclusion, ERP and CBT are the most effective therapies for managing OCD, while other therapies such as transactional analysis, psychoanalysis, counselling, and EMDR are not recommended.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 3 - A 30-year-old man is exhibiting changes in mental status. He has been staying...

    Correct

    • A 30-year-old man is exhibiting changes in mental status. He has been staying up most nights for the past month, working on four different novels simultaneously. He has not left his home or eaten in the last week and refuses to do so. Additionally, he has started gambling. During the consultation, he appears easily distracted and responds to questions with nonsensical sentences made up of random words. A collateral history was necessary to gather information. There is no evidence of drug misuse, and he is currently being treated for depression. When his family attempts to understand his behavior, he accuses them of trying to hold him back from achieving fame. What is the most likely diagnosis?

      Your Answer: Bipolar disorder (type I)

      Explanation:

      The patient is most likely suffering from bipolar disorder (type I) due to their elevated mood and energy following treatment for depression, which can often be a sign of bipolar disorder unmasked by antidepressants. The presence of disorganized speech in the form of ‘word salad’ is evidence of psychosis, which is a characteristic of bipolar I. The patient has also not slept or eaten in the last week, indicating severe functional impairment and the need for hospitalization, which is another DSM-V criteria for bipolar I. Additionally, the patient exhibits decreased need for sleep, increased risky activities, increased goal-directed behavior, and distractibility, which are all symptoms of bipolar I.

      Bipolar disorder (type II) is unlikely as the patient’s disorganized speech suggests psychosis, which is more commonly associated with bipolar I. Schizoaffective disorder is also unlikely as the patient’s elevated mood and history of depression do not fit the diagnostic criteria. Schizophrenia is less likely as it typically presents with negative symptoms followed by delusions and hallucinations, whereas the patient’s symptoms are primarily manic in nature.

      Understanding Psychosis

      Psychosis is a term used to describe a person’s experience of perceiving things differently from those around them. This can manifest in various ways, including hallucinations, delusions, thought disorganization, alogia, tangentiality, clanging, and word salad. Associated features may include agitation/aggression, neurocognitive impairment, depression, and thoughts of self-harm. Psychotic symptoms can occur in a range of conditions, such as schizophrenia, depression, bipolar disorder, puerperal psychosis, brief psychotic disorder, neurological conditions, and drug use. The peak age of first-episode psychosis is around 15-30 years.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 4 - A 9-year-old patient is brought to the general practitioner by his parents because...

    Correct

    • A 9-year-old patient is brought to the general practitioner by his parents because he has been disruptive at school. His teachers report that he does not pay attention in class, bullies other classmates and takes their food during lunchtime without their permission. One teacher also reported that the patient was seen hurting the class hamster.
      What is the most probable diagnosis for this patient?

      Your Answer: Conduct disorder

      Explanation:

      Differentiating between Conduct Disorder, Major Depression, Oppositional Defiant Disorder, Antisocial Disorder, and Manic Episode

      Conduct Disorder, Major Depression, Oppositional Defiant Disorder, Antisocial Disorder, and Manic Episode are all mental health conditions that can present with similar symptoms. However, each disorder has its own unique characteristics that differentiate it from the others.

      Conduct Disorder is a disorder that affects individuals under the age of 18 and is associated with disruptive, bullying behavior and often torture of animals. It is characterized by repetitive behavior that violates the rights of others.

      Major Depression is associated with depressed mood, in addition to five of the following symptoms: sleep changes, loss of interest in previous hobbies or activities, guilt, decreased energy, difficulty concentrating, changes in appetite, sluggishness, and suicidal thoughts persisting for 2 weeks.

      Oppositional Defiant Disorder is characterized by behavior in opposition to authority, but there is no violation of the rights of others or extreme behavior such as bullying or animal cruelty.

      Antisocial Disorder is diagnosed in individuals who are 18 or older and exhibit signs of Conduct Disorder. It is characterized by a disregard for the rights of others and a lack of empathy.

      Manic Episode is associated with elevated mood lasting for 7 days. These patients feel as though they have increased energy, do not need sleep, engage in risky sexual activity and sometimes illicit behavior, feel above the law or invincible, are easily distractible, have flight of fancy, are agitated, and have pressured speech.

      It is important to differentiate between these disorders to ensure that individuals receive the appropriate treatment and support for their specific condition.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 5 - You are asked to see a 50-year-old woman who reports feeling down for...

    Correct

    • You are asked to see a 50-year-old woman who reports feeling down for several months. Upon further questioning, you discover that she has lost interest in activities she previously enjoyed, such as hiking and going to the theater. She has also been experiencing fatigue, causing her to miss work, and has had occasional thoughts of not wanting to be alive, although she denies any intention of harming herself. In the past month, her symptoms have worsened, with episodes of anxiety occurring at least once a week. These episodes last around five minutes and are characterized by hyperventilation, nausea, and a fear of having a heart attack. No physical abnormalities have been found. What is the most likely diagnosis?

      Your Answer: Depression with secondary panic attacks

      Explanation:

      Understanding Different Types of Anxiety and Related Disorders

      Anxiety and related disorders can manifest in various ways, making it important to understand the different types and their symptoms. Depression with secondary panic attacks is a common occurrence, where panic attacks and other anxiety symptoms are a secondary feature of depression. Agoraphobia is an excessive fear of being in situations where escape or help may not be available, leading to avoidance of such situations. Generalised anxiety disorder is characterised by uncontrollable and irrational worry or anxiety about a wide range of issues and situations. Panic disorder is diagnosed when a person has recurrent, severe panic attacks without an obvious precipitant. Chronic fatigue syndrome is characterised by persistent, unexplained fatigue over several months. Understanding these disorders and their symptoms can help in proper diagnosis and treatment.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 6 - A 35-year-old man is brought to the psychiatric unit due to his abnormal...

    Correct

    • A 35-year-old man is brought to the psychiatric unit due to his abnormal behaviour in a police cell. He claimed that there was a conspiracy against him and started acting irrationally. After 36 hours of admission, the patient complains of visual hallucinations and experiences a grand-mal seizure. What is the probable reason behind the seizure?

      Your Answer: Withdrawal from alcohol

      Explanation:

      Possible Causes of Fits in a Patient with a History of Substance Abuse

      There are several possible causes of fits in a patient with a history of substance abuse. LSD withdrawal and amphetamine withdrawal are not known to cause seizures, but amphetamine withdrawal may lead to depression, intense hunger, and lethargy. Hypercalcaemia is not likely to be the cause of fits in this patient, but hyponatraemia due to water intoxication following ecstasy abuse is a possibility. Alcohol withdrawal is a well-known cause of fits in habitual abusers, along with altered behavior. Although idiopathic epilepsy is a differential diagnosis, it is unlikely given the patient’s history of substance abuse. Overall, there are several potential causes of fits in this patient, and further investigation is necessary to determine the underlying cause.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 7 - A 25-year-old woman comes to her doctor's office seeking assistance for her anxiety....

    Correct

    • A 25-year-old woman comes to her doctor's office seeking assistance for her anxiety. She feels overwhelmed by her job, particularly when it comes to communicating with coworkers and superiors, as she is afraid of being criticized. In her personal life, she frequently worries about how her friends perceive her and often avoids socializing with them as a result. She admits to having low self-esteem and a negative self-image. What is the most appropriate diagnosis for her?

      Your Answer: Avoidant personality disorder

      Explanation:

      Patients diagnosed with avoidant personality disorder exhibit a strong fear of criticism, rejection, ridicule, and being disliked. They tend to avoid social and occupational activities that involve significant interpersonal contact due to their fear of being criticized or rejected. These individuals have a negative self-image and are preoccupied with the idea that they are being criticized or rejected in social situations. Although they crave social contact, they tend to isolate themselves socially. This disorder is distinct from other personality disorders such as antisocial personality disorder, borderline personality disorder, and dependent personality disorder, which present with different symptoms and behaviors.

      Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.

      Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspiratorial beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.

      Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 8 - A 25-year-old man has just been diagnosed with schizophrenia. His family is concerned...

    Correct

    • A 25-year-old man has just been diagnosed with schizophrenia. His family is concerned about the long-term outlook of the illness. What factor is linked to the poorest prognosis for poorly managed schizophrenia?

      Your Answer: Gradual onset

      Explanation:

      Schizophrenia with a gradual onset is indicative of a poor prognosis, whereas the other options suggest a better outcome. Although some studies have linked high intelligence with a higher risk of suicide, generally, individuals with higher intelligence have a more favorable prognosis for schizophrenia.

      Schizophrenia is a mental disorder that can have varying prognosis depending on certain factors. Some indicators associated with a poor prognosis include a strong family history of the disorder, a gradual onset of symptoms, a low IQ, a prodromal phase of social withdrawal, and a lack of an obvious precipitant. These factors can contribute to a more severe and chronic course of the illness, making it more difficult to manage and treat. It is important for individuals with schizophrenia and their loved ones to be aware of these indicators and seek appropriate treatment and support.

    • This question is part of the following fields:

      • Psychiatry
      7.5
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  • Question 9 - A 58-year-old woman is brought to the psychiatric ward by her family due...

    Correct

    • A 58-year-old woman is brought to the psychiatric ward by her family due to concerns about her behavior. During your conversation with her, you observe that she speaks rapidly and does not allow you to interrupt her. She frequently changes the subject, but you can discern connections between them. What psychiatric disorder is most commonly associated with these symptoms?

      Your Answer: Bipolar disorder

      Explanation:

      Mania is often characterized by flight of ideas, which is when a person speaks rapidly and jumps between different topics. This is a common symptom of bipolar disorder. It is important to differentiate flight of ideas from Knight’s move thinking, which is associated with schizophrenia. In flight of ideas, there are identifiable connections between the topics that the person jumps between, while in Knight’s move thinking, there are no apparent connections between the topics. This is referred to as loosening of association.

      Thought disorders can manifest in various ways, including circumstantiality, tangentiality, neologisms, clang associations, word salad, Knight’s move thinking, flight of ideas, perseveration, and echolalia. Circumstantiality involves providing excessive and unnecessary detail when answering a question, but eventually returning to the original point. Tangentiality, on the other hand, refers to wandering from a topic without returning to it. Neologisms are newly formed words, often created by combining two existing words. Clang associations occur when ideas are related only by their similar sounds or rhymes. Word salad is a type of speech that is completely incoherent, with real words strung together into nonsensical sentences. Knight’s move thinking is a severe form of loosening of associations, characterized by unexpected and illogical leaps from one idea to another. Flight of ideas is a thought disorder that involves jumping from one topic to another, but with discernible links between them. Perseveration is the repetition of ideas or words despite attempts to change the topic. Finally, echolalia is the repetition of someone else’s speech, including the question that was asked.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 10 - A 28-year-old woman contacts her doctor seeking guidance on stopping all of her...

    Correct

    • A 28-year-old woman contacts her doctor seeking guidance on stopping all of her medications abruptly. She has a medical history of asthma, depression, and occasional tennis elbow pain, for which she takes a salbutamol inhaler, citalopram, and paracetamol, respectively. What is the most probable outcome if she discontinues her medications suddenly?

      Your Answer: Diarrhoea

      Explanation:

      When it comes to discontinuing medication, it’s important to note the specific drug being used. Abruptly stopping a salbutamol inhaler or paracetamol is unlikely to cause any adverse effects. However, stopping a selective serotonin reuptake inhibitor (SSRI) like citalopram can lead to discontinuation symptoms. Gastrointestinal side-effects, such as diarrhoea, are commonly seen in SSRI discontinuation syndrome. To avoid this, it’s recommended to gradually taper off SSRIs. Blunted affect is not likely to occur as a result of sudden discontinuation, but emotional lability and mood swings may be observed. Cyanopsia, or blue-tinted vision, is not a known symptom of SSRI discontinuation, but it can be a side effect of other drugs like sildenafil. While hypertension has been reported in some cases, it’s less common than gastrointestinal symptoms. Weight loss, rather than weight gain, is often reported upon sudden discontinuation of SSRIs.

      Selective serotonin reuptake inhibitors (SSRIs) are commonly used as the first-line treatment for depression. Citalopram and fluoxetine are the preferred SSRIs, while sertraline is recommended for patients who have had a myocardial infarction. However, caution should be exercised when prescribing SSRIs to children and adolescents. Gastrointestinal symptoms are the most common side-effect, and patients taking SSRIs are at an increased risk of gastrointestinal bleeding. Patients should also be aware of the possibility of increased anxiety and agitation after starting a SSRI. Fluoxetine and paroxetine have a higher propensity for drug interactions.

      The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a warning regarding the use of citalopram due to its association with dose-dependent QT interval prolongation. As a result, citalopram and escitalopram should not be used in patients with congenital long QT syndrome, known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval. The maximum daily dose of citalopram is now 40 mg for adults, 20 mg for patients older than 65 years, and 20 mg for those with hepatic impairment.

      When initiating antidepressant therapy, patients should be reviewed by a doctor after 2 weeks. Patients under the age of 25 years or at an increased risk of suicide should be reviewed after 1 week. If a patient responds well to antidepressant therapy, they should continue treatment for at least 6 months after remission to reduce the risk of relapse. When stopping a SSRI, the dose should be gradually reduced over a 4 week period, except for fluoxetine. Paroxetine has a higher incidence of discontinuation symptoms, including mood changes, restlessness, difficulty sleeping, unsteadiness, sweating, gastrointestinal symptoms, and paraesthesia.

      When considering the use of SSRIs during pregnancy, the benefits and risks should be weighed. Use during the first trimester may increase the risk of congenital heart defects, while use during the third trimester can result in persistent pulmonary hypertension of the newborn. Paroxetine has an increased risk of congenital malformations, particularly in the first trimester.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 11 - A 21-year-old woman is brought to her General Practitioner for follow-up 1 week...

    Correct

    • A 21-year-old woman is brought to her General Practitioner for follow-up 1 week after being attacked and raped by an acquaintance on her university campus. Immediately after the episode, she was seen in the Emergency Department for her injuries and evidence gathering, interviewed by the police and discharged home. Today she reports difficulty sleeping and flashbacks about the event. She has had difficulty concentrating at university and feels anxious that ‘something bad’ might happen to her again.
      Which one of the following is the most likely diagnosis?

      Your Answer: Acute stress disorder

      Explanation:

      Differentiating between Acute Stress Disorder, Adjustment Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, and Panic Disorder

      Acute Stress Disorder: This disorder is characterized by persistently heightened awareness, difficulty sleeping, flashbacks, and interference of thoughts with daily activities. It occurs within 1 month of a life-threatening or extremely traumatic event.

      Adjustment Disorder: To diagnose this disorder, there must be an identifiable stressor, a maladaptive response to the stressor that interferes with activities, symptom onset within 3 months of the stressor, and symptoms that do not meet criteria for any other psychiatric disorder. Symptoms typically last no longer than 6 months after removal of the stressor.

      Generalized Anxiety Disorder: This disorder is characterized by pervasive, excessive worry about many different aspects of a person’s life such as finances, work, and family. It often manifests first with somatic symptoms such as fatigue, difficulty sleeping, irritability, and muscle tension.

      Post-Traumatic Stress Disorder (PTSD): If symptoms persist longer than 1 month, patients meet criteria for PTSD. The diagnostic differentiation between acute stress and PTSD is the duration of symptoms only.

      Panic Disorder: This disorder is characterized by shortness of breath, chest pain, palpitations, diaphoresis, nausea, choking, abdominal distress, and feelings of impending doom. Symptoms mimic those of extreme autonomic arousal, are abrupt in onset, and resolve quickly.

    • This question is part of the following fields:

      • Psychiatry
      62
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  • Question 12 - A 30-year-old woman, with a history of hearing voices, was brought to the...

    Incorrect

    • A 30-year-old woman, with a history of hearing voices, was brought to the Emergency Department by her family. She described the voices as telling her to kill her father as ‘he has the devil in him’. She also reported noting her intelligence being tapped through the Internet by a higher power. This has been going on for the past 6 months. Her family denies either depression or manic episodes. The patient was admitted to an inpatient Psychiatry Unit and started on haloperidol for her symptoms, after an evaluation and diagnosis of schizophrenia. Twelve hours after initiation of therapy, the patient started to have stiffness in the neck muscles and spine. Physical examination revealed muscular spasms in the neck and spine, a temperature of 37.2 °C, blood pressure 125/70 mmHg and a pulse of 80 bpm.
      What is the most likely diagnosis?

      Your Answer: Neuroleptic malignant syndrome

      Correct Answer: Acute dystonia

      Explanation:

      Complications of Haloperidol: Acute Dystonia, Neuroleptic Malignant Syndrome, Serotonin Syndrome, and Meningitis

      Haloperidol is an anti-psychotic medication commonly used to treat schizophrenia. However, it can also cause various complications. Acute dystonia is a condition where the patient experiences muscle spasms in different muscle groups, which can occur shortly after taking haloperidol. Treatment for acute dystonia involves administering anticholinergics.

      Neuroleptic malignant syndrome is another complication that can occur as a result of taking anti-psychotic medication, particularly high-potency ones like haloperidol. Symptoms include abnormal vital signs, such as high fever, and treatment involves discontinuing the medication and managing symptoms with cooling measures and medications like dantrolene or bromocriptine.

      Serotonin syndrome is a condition that can occur when a patient takes multiple doses or an overdose of medications like selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or serotonin agonists like sumatriptans. Symptoms include muscular twitching, agitation, confusion, hyperthermia, sweating, hypertension, tachycardia, and diarrhea.

      Meningitis, on the other hand, is not a complication of haloperidol. It is an inflammation of the protective membranes surrounding the brain and spinal cord, usually caused by a bacterial or viral infection.

      Finally, malignant hyperthermia is a condition that can manifest with similar symptoms to neuroleptic malignant syndrome, but it usually occurs during anesthesia administration and is caused by an inherited autosomal dominant disorder of the ryanodine receptor gene in the skeletal muscle. Treatment involves using dantrolene and providing supportive care.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 13 - A 42-year-old woman visits the clinic with her husband, who is worried about...

    Correct

    • A 42-year-old woman visits the clinic with her husband, who is worried about her recent change in behavior. For the past two weeks, she has been acting out of character, spending large amounts of money on credit cards and wearing bold makeup and clothes that she wouldn't normally choose. She has also been experiencing insomnia, often staying up late at night to work on important projects that she can't disclose to her husband. The patient has a history of depression, and her mother was hospitalized for mental illness. What is the most probable diagnosis for this patient?

      Your Answer: Bipolar Disorder

      Explanation:

      Differentiating Mental Disorders: Understanding the Symptoms

      Bipolar Disorder:
      A patient showing signs of mania, such as inflated self-esteem, pressured speech, reduced need for sleep, and engaging in high-risk behaviors, may be diagnosed with bipolar disorder. A manic episode requires a disturbed mood plus three of the above symptoms. A history of depression and a family history of psychiatric conditions, such as bipolar disorder, further support this diagnosis.

      Personality Disorder:
      Personality disorders are maladaptive mental disorders that typically develop at an early age. A patient in their mid-forties who has recently started experiencing mood-related symptoms, such as depression and mania, is unlikely to have a personality disorder. Types of personality disorders include paranoid, schizoid, schizotypal, borderline, histrionic, narcissistic, and obsessive-compulsive.

      Anxiety Disorder:
      Symptoms of anxiety include social withdrawal, excessive worry, and avoidance of risk. A patient exhibiting symptoms of mania, such as high energy and engaging in risky behaviors, is not displaying signs of anxiety disorder. However, anxiety disorder may coexist with bipolar disorder.

      Depression:
      Depression is characterized by low mood, lack of enjoyment in activities, difficulty concentrating, and suicidal thoughts. A patient who has a history of depression but is currently experiencing symptoms of mania is not exhibiting signs of depression.

      Schizophrenia:
      Schizophrenia is a complex mental disorder that requires several criteria for diagnosis. Symptoms include hallucinations, disordered speech and thought, paranoia, and social withdrawal. A patient who does not exhibit these symptoms is not eligible for a differential diagnosis of schizophrenia.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 14 - A 36-year-old woman presents to her doctor with complaints of struggling to maintain...

    Correct

    • A 36-year-old woman presents to her doctor with complaints of struggling to maintain positive relationships with her coworkers. Upon further inquiry, it is revealed that the woman has a rigid value system and moral code, making it challenging for her to work with colleagues who have different beliefs and work practices. What personality disorder is most likely present in this patient?

      Your Answer: Obsessive-compulsive personality disorder

      Explanation:

      Patients with obsessive-compulsive personality disorder tend to be inflexible when it comes to morals, ethics, and values. They often have difficulty delegating tasks to others, as seen in this case. Other symptoms include an excessive focus on details, rules, lists, and order, as well as perfectionism that can interfere with completing tasks.

      Antisocial personality disorder is not applicable in this case. This disorder is characterized by aggressive and unlawful behavior, deception, and a lack of empathy.

      Borderline personality disorder is also not applicable. This disorder is characterized by unstable self-image, unstable relationships, fear of abandonment, and chronic feelings of emptiness.

      Paranoid personality disorder is not applicable. This disorder is characterized by a tendency to question the loyalty of friends, hypersensitivity to insult, and preoccupation with conspiracies and hidden meanings.

      Narcissistic personality disorder is not applicable. This disorder is characterized by a grandiose sense of self-importance, lack of empathy, sense of entitlement, and preoccupation with fantasies of success, power, or beauty.

      Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.

      Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspiratorial beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.

      Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 15 - An 81-year-old man is transferred from a nursing home with a change in...

    Correct

    • An 81-year-old man is transferred from a nursing home with a change in behaviour, insomnia and fever. Staff in the nursing home state that over the last five days, he has appeared confused and agitated and seems to be having visual hallucinations, as he has been talking and gesturing to people who are not present in the room. He has a past medical history of Lewy body dementia. On clinical examination, he is not orientated to time, place or person. He is mildly agitated. His blood pressure is 112/60 mmHg, pulse 96 bpm and temperature 38.2 °C. Urinalysis is positive for nitrites and leukocytes.
      Which of the following management plans should be considered as initial treatment for delirium?

      Your Answer: Treat the underlying cause, ensure effective communication and reorientation, provide reassurance for people diagnosed with delirium, provide a suitable care environment

      Explanation:

      Managing Delirium: Strategies for Treatment and Care Environment

      Delirium is a serious condition that requires prompt identification and management of underlying causes. Effective communication and reorientation, as well as reassurance for the patient, are crucial in managing delirium. Involving family, friends, and carers can also be helpful. Providing a suitable care environment, such as a well-lit and quiet room with minimal stimulation, is important. If verbal and non-verbal de-escalation techniques are ineffective, short-term use of antipsychotic drugs like haloperidol or olanzapine may be necessary, but caution should be exercised, especially for patients with conditions like Parkinson’s disease or dementia with Lewy bodies. Frequent reorientation and monitoring in a dimly lit room may also be necessary in some cases. Overall, a comprehensive approach that addresses both the underlying causes and the patient’s immediate needs is essential in managing delirium.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 16 - A mother brings her 8-year-old son to see the general practitioner (GP) as...

    Correct

    • A mother brings her 8-year-old son to see the general practitioner (GP) as she is very concerned about his school performance. His teacher has reported that he is being highly disruptive in the classroom.
      Which of the following sets of behaviours fit best with a diagnosis of attention deficit/hyperactivity disorder (ADHD)?

      Your Answer: Easily distracted, hyperactivity, interrupts classmates

      Explanation:

      Understanding ADHD: Symptoms and Risk Factors

      Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that affects both children and adults. The core features of ADHD include inattention, hyperactivity, and impulsiveness. Individuals with ADHD may be easily distracted, forgetful, fidgety, and have difficulty sustaining attention for prolonged periods. They may also interrupt others, talk excessively, and struggle to wait their turn.

      While the exact cause of ADHD is unknown, genetic factors, head injury, and low birthweight are thought to be risk factors. ADHD is more common in men than women. Management of ADHD typically involves counselling and/or medication.

      It is important to note that ADHD does not necessarily lead to difficulties in forming friendships or an inability to empathize with peers. Aggression and destruction are also not core features of ADHD. However, individuals with ADHD may struggle with inflexibility and have difficulty finishing tasks. It is important to understand the symptoms and risk factors associated with ADHD in order to provide appropriate support and management.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 17 - A 27-year-old man is brought to the emergency department by police after being...

    Correct

    • A 27-year-old man is brought to the emergency department by police after being found naked in the street and shouting about the government's plan to infect the population with a virus through the water supply. He is not known to secondary care services and a drug screen is negative. The psychiatry liaison team admits him under Section 2 of the Mental Health Act for assessment of a first psychosis. What is the most significant risk factor for this patient's condition?

      Your Answer: Uncle with schizophrenia

      Explanation:

      The most significant risk factor for psychotic disorders is a person’s family history.

      Understanding the Epidemiology of Schizophrenia

      Schizophrenia is a psychotic disorder that affects a significant portion of the population. The strongest risk factor for developing this condition is having a family history of the disorder. Individuals with a parent who has schizophrenia have a relative risk of 7.5. Additionally, monozygotic twins have a 50% chance of developing schizophrenia, while siblings have a 10% chance. In contrast, individuals without relatives with schizophrenia have a 1% chance of developing the disorder.

      Aside from family history, other factors can increase the risk of developing schizophrenia. Black Caribbean ethnicity has a relative risk of 5.4, while migration and living in an urban environment have relative risks of 2.9 and 2.4, respectively. Cannabis use also increases the risk of developing schizophrenia, with a relative risk of 1.4.

      Understanding the epidemiology of schizophrenia is crucial in identifying individuals who may be at risk of developing the disorder. By recognizing these risk factors, healthcare professionals can provide early interventions and support to prevent or manage the onset of schizophrenia.

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      • Psychiatry
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  • Question 18 - A 28-year-old woman is admitted to the psychiatric ward under section 2 of...

    Incorrect

    • A 28-year-old woman is admitted to the psychiatric ward under section 2 of the mental health act for suspected bipolar disorder. She has a 4-month history of manic episodes and has been experiencing delusions of grandeur. She started lithium 3 weeks ago. She has no other medical conditions and takes no other medications. Today, staff on the ward raised concerns due to her abnormal behaviour. She was found in the common room dancing and singing loudly, despite it being late at night. It is reported that she has been like this for the last hour. Her observations are normal. She has not responded to attempts to engage her in conversation or to calm her down. What is the most appropriate description of her current presentation?

      Your Answer: Tetany

      Correct Answer: Catatonia

      Explanation:

      The most likely cause of the woman’s presentation, who is suspected to have schizophrenia and has been sitting in an uncomfortable position for the last 2 hours, is catatonia. Catatonia is a condition where voluntary movement is stopped or the person stays in an unusual position. It is believed to occur due to abnormalities in the balance of neurotransmitter systems, particularly dopamine, and is commonly associated with certain types of schizophrenia. Treatment for catatonia includes benzodiazepines and electroconvulsive therapy.

      Extrapyramidal side effects, neuroleptic malignant syndrome, and serotonin syndrome are not the correct answers for this scenario. Extrapyramidal side effects can occur with antipsychotic medications but would not present with the withdrawn status described. Neuroleptic malignant syndrome is a life-threatening reaction to antipsychotic medications and presents with different symptoms than catatonia. Serotonin syndrome is caused by excess serotonin in the body and is not associated with the patient’s medication or presentation.

      Schizophrenia is a mental disorder that is characterized by various symptoms. Schneider’s first rank symptoms are divided into four categories: auditory hallucinations, thought disorders, passivity phenomena, and delusional perceptions. Auditory hallucinations can include hearing two or more voices discussing the patient in the third person, thought echo, or voices commenting on the patient’s behavior. Thought disorders can involve thought insertion, thought withdrawal, or thought broadcasting. Passivity phenomena can include bodily sensations being controlled by external influence or actions/impulses/feelings that are imposed on the individual or influenced by others. Delusional perceptions involve a two-stage process where a normal object is perceived, and then there is a sudden intense delusional insight into the object’s meaning for the patient.

      Other features of schizophrenia include impaired insight, incongruity/blunting of affect (inappropriate emotion for circumstances), decreased speech, neologisms (made-up words), catatonia, and negative symptoms such as incongruity/blunting of affect, anhedonia (inability to derive pleasure), alogia (poverty of speech), and avolition (poor motivation). It is important to note that schizophrenia can manifest differently in each individual, and not all symptoms may be present.

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      • Psychiatry
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  • Question 19 - A 16-year-old boy with Tourette's syndrome is brought to the GP by his...

    Correct

    • A 16-year-old boy with Tourette's syndrome is brought to the GP by his father as he is concerned about some unusual behaviors he has observed. During the appointment, you discover that he has been extremely anxious about his upcoming driving test. He feels compelled to check the locks on all the doors in the house repeatedly before leaving, as otherwise, he becomes more anxious about the test.

      What signs or symptoms would suggest a diagnosis of psychosis rather than obsessive-compulsive disorder?

      Your Answer: She truly believes that if she does not perform these acts that she will definitely fail her exams

      Explanation:

      The level of insight into their actions can differentiate obsessive-compulsive disorder from psychosis. OCD is characterized by obsessions and compulsions, where patients have intrusive thoughts and perform acts to reduce them. Patients with OCD typically have a good understanding of their condition and know that not performing the acts will not make their obsessive thoughts come true. However, they still feel the urge to perform them. If a patient lacks insight into their condition and believes that not performing the acts will lead to a negative outcome, it may indicate a delusional element and suggest a diagnosis other than OCD, such as psychosis. Gender is not linked to OCD, and Tourette’s is associated with OCD, not psychosis. Patients with untreated OCD may need to perform more acts over time, but this does not indicate psychosis. While there is a genetic link to OCD, the absence of a family history does not suggest another underlying diagnosis.

      Obsessive-compulsive disorder (OCD) is characterized by the presence of obsessions and/or compulsions that can cause significant functional impairment and distress. Risk factors include family history, age, pregnancy/postnatal period, and history of abuse, bullying, or neglect. Treatment options include low-intensity psychological treatments, SSRIs, and more intensive CBT (including ERP). Severe cases should be referred to the secondary care mental health team for assessment and may require combined treatment with an SSRI and CBT or clomipramine as an alternative. ERP involves exposing the patient to an anxiety-provoking situation and stopping them from engaging in their usual safety behavior. Treatment with SSRIs should continue for at least 12 months to prevent relapse and allow time for improvement.

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      • Psychiatry
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  • Question 20 - A 28-year-old man visits his General Practitioner on the advice of the Community...

    Incorrect

    • A 28-year-old man visits his General Practitioner on the advice of the Community Psychiatric Nurse. He has been experiencing a fever and sore throat lately. He is currently on clozapine for treatment-resistant schizophrenia.
      What would be the most crucial investigation to conduct, considering his recent symptoms?

      Your Answer: Electrocardiogram (ECG)

      Correct Answer: Full blood count

      Explanation:

      When treating patients with clozapine, it is important to monitor for agranulocytosis, a rare but potentially fatal side-effect. Patients should report flu-like symptoms and undergo regular blood tests. In this case, the patient’s sore throat and fever may indicate agranulocytosis, so a full blood count is necessary. While an ECG should be done before starting antipsychotic treatment, it is not the most important test in this scenario. Blood glucose should be monitored to exclude organic causes and hyperglycemia caused by antipsychotics. Liver function and urea/electrolytes should also be monitored regularly, but are not the most important tests to conduct immediately in this case.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 21 - A 29-year-old woman arrives at the Emergency Department in a state of distress....

    Incorrect

    • A 29-year-old woman arrives at the Emergency Department in a state of distress. She admits to having lost a significant amount of money through gambling and then taking 4 packets of paracetamol. This is not the first time she has engaged in such behavior. She discloses that her partner of 3 years has been offered a job overseas and is considering accepting it. Despite her initial heartbreak, they had a major argument and she now claims to be indifferent about whether he stays or goes.

      What is the most appropriate course of action based on the probable diagnosis?

      Your Answer: Cognitive behaviour therapy

      Correct Answer: Dialectical behaviour therapy

      Explanation:

      Borderline personality disorder (BPD) is characterized by recurrent self-harm and intense interpersonal relationships that alternate between idealization and devaluation as a way to cope with strong emotions during strained relationships. The defense mechanism of devaluation is evident in the patient’s quick emotional switches, without middle ground. Dialectical behavior therapy is an effective treatment for BPD, while cognitive behavior therapy is more suitable for depression or anxiety disorders. The clinical picture is more consistent with BPD than depression, and antidepressants may not be effective for BPD. Lithium, the mood stabilizer of choice for bipolar disorder, is not appropriate for this acute event, which occurred over the past few hours rather than days.

      Personality disorders are a set of personality traits that are maladaptive and interfere with normal functioning in life. It is estimated that around 1 in 20 people have a personality disorder, which are typically categorized into three clusters: Cluster A, which includes Odd or Eccentric disorders such as Paranoid, Schizoid, and Schizotypal; Cluster B, which includes Dramatic, Emotional, or Erratic disorders such as Antisocial, Borderline (Emotionally Unstable), Histrionic, and Narcissistic; and Cluster C, which includes Anxious and Fearful disorders such as Obsessive-Compulsive, Avoidant, and Dependent.

      Paranoid individuals exhibit hypersensitivity and an unforgiving attitude when insulted, a reluctance to confide in others, and a preoccupation with conspiratorial beliefs and hidden meanings. Schizoid individuals show indifference to praise and criticism, a preference for solitary activities, and emotional coldness. Schizotypal individuals exhibit odd beliefs and magical thinking, unusual perceptual disturbances, and inappropriate affect. Antisocial individuals fail to conform to social norms, deceive others, and exhibit impulsiveness, irritability, and aggressiveness. Borderline individuals exhibit unstable interpersonal relationships, impulsivity, and affective instability. Histrionic individuals exhibit inappropriate sexual seductiveness, a need to be the center of attention, and self-dramatization. Narcissistic individuals exhibit a grandiose sense of self-importance, lack of empathy, and excessive need for admiration. Obsessive-compulsive individuals are occupied with details, rules, and organization to the point of hampering completion of tasks. Avoidant individuals avoid interpersonal contact due to fears of criticism or rejection, while dependent individuals have difficulty making decisions without excessive reassurance from others.

      Personality disorders are difficult to treat, but a number of approaches have been shown to help patients, including psychological therapies such as dialectical behavior therapy and treatment of any coexisting psychiatric conditions.

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      • Psychiatry
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  • Question 22 - A 30-year-old woman presents to you with complaints of feeling down and fatigued....

    Correct

    • A 30-year-old woman presents to you with complaints of feeling down and fatigued. She struggles to fall asleep at night and has difficulty getting up in the morning. Despite her love for exercise, she lacks motivation and finds it hard to engage in physical activity.

      What is the duration of her symptoms that would warrant a diagnosis of a depressive episode?

      Your Answer: Two weeks

      Explanation:

      DSM-IV Criteria for Diagnosing Depression

      Depression is a mental health condition that can significantly impact a person’s daily life. The National Institute for Health and Care Excellence (NICE) has adopted the DSM-IV criteria for diagnosing depression. The key symptoms include persistent sadness or low mood and marked loss of interests or pleasure. These symptoms must be present for at least two weeks, most days, most of the time.

      In addition to the core symptoms, other associated symptoms may include disturbed sleep, changes in appetite and weight, fatigue, agitation or slowing of movements, poor concentration or indecisiveness, feelings of worthlessness or excessive guilt, and suicidal thoughts or acts.

      It is important to note that these symptoms can vary in duration. Some individuals may experience symptoms for only two days, while others may experience them for up to two months. If you or someone you know is experiencing symptoms of depression, it is important to seek professional help.

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      • Psychiatry
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  • Question 23 - A 9-year-old girl is brought to see the General Practitioner (GP) by her...

    Correct

    • A 9-year-old girl is brought to see the General Practitioner (GP) by her father, who is concerned about her behaviour at home and school. Over the past 18 months, her father has noted problems with inattention, hyperactivity and impulsivity. Teachers have also been raising similar issues about her behaviour in school. Her symptoms are affecting her performance in school and her relationship at home with her parents and siblings.
      Which one of the following conditions is she most likely to be diagnosed with?

      Your Answer: Attention deficit/hyperactivity disorder (ADHD)

      Explanation:

      The patient is exhibiting signs of ADHD, which is characterized by persistent patterns of inattention, hyperactivity, and impulsivity that interfere with functioning or development. These symptoms must have been present before the age of 12 and evident in multiple settings for at least six months. However, there are no indications of autism spectrum disorder, learning difficulty, or learning disability. Additionally, the patient does not display any symptoms of oppositional defiance disorder, which is characterized by angry or irritable mood, argumentative behavior, or vindictiveness lasting at least six months and causing distress or impairment in social, educational, or occupational functioning.

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      • Psychiatry
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  • Question 24 - A 26-year-old female smoker comes to your clinic with a complaint of difficulty...

    Correct

    • A 26-year-old female smoker comes to your clinic with a complaint of difficulty sleeping for the past 6 months. She often stays awake for hours worrying before finally falling asleep, which is affecting her work concentration. You observe that she seems restless and fidgety during the consultation. Upon reviewing her medical records, you discover that she has recently experienced abdominal pain and palpitations. What is the crucial condition to exclude before diagnosing her with generalized anxiety disorder?

      Your Answer: Hyperthyroidism

      Explanation:

      When diagnosing anxiety, it is important to rule out thyroid disease as the symptoms of anxiety and hyperthyroidism can be similar. Hyperthyroidism can both cause and worsen anxiety. While phaeochromocytoma and Wilson’s disease are possible alternative diagnoses, they are not typically considered before diagnosing anxiety. It is worth noting that insomnia is a symptom of anxiety rather than a separate diagnosis.

      Anxiety is a common disorder that can manifest in various ways. According to NICE, the primary feature is excessive worry about multiple events associated with heightened tension. It is crucial to consider potential physical causes when diagnosing anxiety disorders, such as hyperthyroidism, cardiac disease, and medication-induced anxiety. Medications that may trigger anxiety include salbutamol, theophylline, corticosteroids, antidepressants, and caffeine.

      NICE recommends a step-wise approach for managing generalised anxiety disorder (GAD). This includes education about GAD and active monitoring, low-intensity psychological interventions, high-intensity psychological interventions or drug treatment, and highly specialist input. Sertraline is the first-line SSRI for drug treatment, and if it is ineffective, an alternative SSRI or a serotonin-noradrenaline reuptake inhibitor (SNRI) such as duloxetine or venlafaxine may be offered. If the patient cannot tolerate SSRIs or SNRIs, pregabalin may be considered. For patients under 30 years old, NICE recommends warning them of the increased risk of suicidal thinking and self-harm and weekly follow-up for the first month.

      The management of panic disorder also follows a stepwise approach, including recognition and diagnosis, treatment in primary care, review and consideration of alternative treatments, review and referral to specialist mental health services, and care in specialist mental health services. NICE recommends either cognitive behavioural therapy or drug treatment in primary care. SSRIs are the first-line drug treatment, and if contraindicated or no response after 12 weeks, imipramine or clomipramine should be offered.

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      • Psychiatry
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  • Question 25 - A 29-year-old man presented to the hospital, accompanied by the police after having...

    Correct

    • A 29-year-old man presented to the hospital, accompanied by the police after having had a fight in a casino. The casino manager called the police when the man refused to leave after he had spent almost 24 hours gambling. The patient ran out of money and was harassing other clients, trying to borrow money from them and telling them that he will return it after he had won and invested the prize money. The patient has no known next of kin and refuses to engage with the attending doctor. He threatens to assault the medical staff and is eventually put under urgent mental health Section 4. A review of his medical notes reveals that the only medication on which he has been is lithium for a known psychiatric illness, but he has not been in touch with his general practitioner for the past two months.
      What is the best course of action for managing this patient?

      Your Answer: Check the lithium levels and consider adding olanzapine

      Explanation:

      Management of Bipolar Depression with Mania or Hypomania

      According to the latest NICE guideline CG85, patients with bipolar depression presenting with mania or hypomania should have their lithium levels checked and consider adding an antipsychotic such as haloperidol, olanzapine, quetiapine or risperidone. Therefore, checking the lithium levels and considering adding olanzapine is the correct answer in this case.

      Stopping lithium without checking the levels first is not recommended as it is a mood stabiliser and may be required for the patient. Starting haloperidol or risperidone without checking the lithium levels is also not recommended as the doctor must consider the patient’s lithium levels before adding an antipsychotic.

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      • Psychiatry
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  • Question 26 - A 28-year-old female patient complains of experiencing difficulty sleeping for the past six...

    Incorrect

    • A 28-year-old female patient complains of experiencing difficulty sleeping for the past six months. She frequently stays awake at night due to worrying about work and family-related stressors. These episodes of anxiety are often accompanied by chest tightness and palpitations. Despite trying mindfulness, sleep hygiene, and reducing caffeine intake, she has not experienced significant improvement and is now considering medication. What would be the most suitable medication to prescribe?

      Your Answer: Mirtazapine

      Correct Answer: Sertraline

      Explanation:

      Sertraline is the recommended first-line medication for generalised anxiety disorder (GAD). This is because the patient has already tried non-pharmacological measures with little benefit. Diazepam, a benzodiazepine, is not recommended due to the risk of tolerance and addiction. Duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI), is not first-line but may be considered if the patient does not respond to sertraline. Mirtazapine, a noradrenergic and specific serotonergic antidepressant (NaSSA), is not generally recommended for GAD.

      Anxiety is a common disorder that can manifest in various ways. According to NICE, the primary feature is excessive worry about multiple events associated with heightened tension. It is crucial to consider potential physical causes when diagnosing anxiety disorders, such as hyperthyroidism, cardiac disease, and medication-induced anxiety. Medications that may trigger anxiety include salbutamol, theophylline, corticosteroids, antidepressants, and caffeine.

      NICE recommends a step-wise approach for managing generalised anxiety disorder (GAD). This includes education about GAD and active monitoring, low-intensity psychological interventions, high-intensity psychological interventions or drug treatment, and highly specialist input. Sertraline is the first-line SSRI for drug treatment, and if it is ineffective, an alternative SSRI or a serotonin-noradrenaline reuptake inhibitor (SNRI) such as duloxetine or venlafaxine may be offered. If the patient cannot tolerate SSRIs or SNRIs, pregabalin may be considered. For patients under 30 years old, NICE recommends warning them of the increased risk of suicidal thinking and self-harm and weekly follow-up for the first month.

      The management of panic disorder also follows a stepwise approach, including recognition and diagnosis, treatment in primary care, review and consideration of alternative treatments, review and referral to specialist mental health services, and care in specialist mental health services. NICE recommends either cognitive behavioural therapy or drug treatment in primary care. SSRIs are the first-line drug treatment, and if contraindicated or no response after 12 weeks, imipramine or clomipramine should be offered.

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      • Psychiatry
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  • Question 27 - A 47-year-old man visits his General Practitioner with worsening anxiety. He describes one...

    Correct

    • A 47-year-old man visits his General Practitioner with worsening anxiety. He describes one of his symptoms as feeling severely nauseous and even vomiting every time he smells a particular perfume. What theory of learning explains this?

      Your Answer: Classical conditioning

      Explanation:

      Types of Learning and Conditioning in Psychology

      Classical conditioning, latent inhibition, habituation, operant conditioning, and tolerance are all types of learning and conditioning in psychology.

      Classical conditioning involves learning through association, where an unfamiliar stimulus becomes associated with a conditioned response through repetitive exposure.

      Latent inhibition refers to the slower acquisition of meaning or response to a familiar stimulus compared to a new stimulus.

      Habituation is the decrease in responsiveness to a stimulus with repeated exposure.

      Operant conditioning involves learning through positive or negative reinforcement, where a voluntary response is followed by a reinforcing stimulus.

      Tolerance is the reduced response to a drug over time, requiring a higher concentration to achieve the desired effect.

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  • Question 28 - A 33-year-old woman who has never given birth before comes for her first...

    Correct

    • A 33-year-old woman who has never given birth before comes for her first prenatal visit at 29 weeks gestation. She is currently taking fluoxetine and lactulose and is concerned about the potential risks to her baby. What is a possible danger of using fluoxetine during the third trimester of pregnancy?

      Your Answer: Persistent pulmonary hypertension

      Explanation:

      When considering the use of SSRIs during pregnancy, it is important to assess the potential benefits and risks. While using SSRIs during the first trimester may slightly increase the risk of congenital heart defects, using them during the third trimester can lead to persistent pulmonary hypertension of the newborn. Additionally, paroxetine has a higher risk of congenital malformations, especially during the first trimester.

      Selective serotonin reuptake inhibitors (SSRIs) are commonly used as the first-line treatment for depression. Citalopram and fluoxetine are the preferred SSRIs, while sertraline is recommended for patients who have had a myocardial infarction. However, caution should be exercised when prescribing SSRIs to children and adolescents. Gastrointestinal symptoms are the most common side-effect, and patients taking SSRIs are at an increased risk of gastrointestinal bleeding. Patients should also be aware of the possibility of increased anxiety and agitation after starting a SSRI. Fluoxetine and paroxetine have a higher propensity for drug interactions.

      The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a warning regarding the use of citalopram due to its association with dose-dependent QT interval prolongation. As a result, citalopram and escitalopram should not be used in patients with congenital long QT syndrome, known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval. The maximum daily dose of citalopram is now 40 mg for adults, 20 mg for patients older than 65 years, and 20 mg for those with hepatic impairment.

      When initiating antidepressant therapy, patients should be reviewed by a doctor after 2 weeks. Patients under the age of 25 years or at an increased risk of suicide should be reviewed after 1 week. If a patient responds well to antidepressant therapy, they should continue treatment for at least 6 months after remission to reduce the risk of relapse. When stopping a SSRI, the dose should be gradually reduced over a 4 week period, except for fluoxetine. Paroxetine has a higher incidence of discontinuation symptoms, including mood changes, restlessness, difficulty sleeping, unsteadiness, sweating, gastrointestinal symptoms, and paraesthesia.

      When considering the use of SSRIs during pregnancy, the benefits and risks should be weighed. Use during the first trimester may increase the risk of congenital heart defects, while use during the third trimester can result in persistent pulmonary hypertension of the newborn. Paroxetine has an increased risk of congenital malformations, particularly in the first trimester.

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      • Psychiatry
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  • Question 29 - Electroconvulsive Therapy (ECT) is recommended by NICE for which clinical conditions? ...

    Correct

    • Electroconvulsive Therapy (ECT) is recommended by NICE for which clinical conditions?

      Your Answer: In a catatonic patient

      Explanation:

      Electroconvulsive therapy (ECT) should only be considered as a treatment option for individuals with severe major depressive disorder that is potentially life-threatening, and where other treatments have been ineffective. It is also recommended for those experiencing catatonia or a prolonged/severe manic episode.

      Electroconvulsive therapy (ECT) is a viable treatment option for patients who suffer from severe depression that does not respond to medication, such as catatonia, or those who experience psychotic symptoms. The only absolute contraindication for ECT is when a patient has raised intracranial pressure.

      Short-term side effects of ECT include headaches, nausea, short-term memory impairment, memory loss of events prior to the therapy, and cardiac arrhythmia. However, these side effects are typically temporary and resolve quickly.

      Long-term side effects of ECT are less common, but some patients have reported impaired memory. It is important to note that the benefits of ECT often outweigh the potential risks, and it can be a life-changing treatment for those who have not found relief from other forms of therapy.

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  • Question 30 - A 42-year-old man presents to his GP with a sense of sadness and...

    Correct

    • A 42-year-old man presents to his GP with a sense of sadness and emptiness. He lost his job 8 months ago and has been struggling to focus on his daily activities ever since. 'I'm just not the same person I used to be,' he tells the doctor. He has no interest in finding a new job and spends most of his time at home. He denies any thoughts of suicide. His sleep is disturbed and he wakes up feeling tired. He also reports a decreased interest in sex with his partner. His medical history is significant only for a bilateral hand tremor that worsens with movement. He is a non-smoker and only drinks socially. What is the most likely diagnosis?

      Your Answer: Major depressive disorder

      Explanation:

      Distinguishing Major Depressive Disorder from Other Conditions

      Major depressive disorder is a psychiatric condition characterized by symptoms such as anhedonia, sadness, lack of concentration, sleep impairment, social withdrawal, and hopelessness. It is often triggered by a significant stressor, such as job loss. While severe depression can also be a component of adjustment disorder, the duration of symptoms beyond 6 months following a stressor suggests a diagnosis of major depressive disorder. Anhedonia, a significant lack of interest in once pleasurable activities, is a symptom rather than a diagnosis by itself and is often present in major depressive disorder. Drug abuse can be a cause or effect of depression, but in this case, the patient’s recent stressor makes drug-related depression less likely. The patient’s hand tremor, worsened by movement, is more likely related to essential tremor than Parkinson’s disease, which typically presents with a resting hand tremor, rigidity, and bradykinesia. Accurately distinguishing major depressive disorder from other conditions is crucial for effective treatment.

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  • Question 31 - A 48-year-old woman with a history of manic-depressive psychosis, diagnosed at the age...

    Correct

    • A 48-year-old woman with a history of manic-depressive psychosis, diagnosed at the age of 23, presents to her General Practitioner with polydipsia and polyuria. Current medication includes lithium and a steroid inhaler for bronchial asthma. Examination reveals a blood pressure (BP) of 110/75 mmHg, with a pulse of 80 bpm and regular. There are normal fasting sugar levels and there is no postural drop on standing.
      What are the investigation findings most likely to help diagnose this condition?

      Your Answer: Low urine osmolality and high serum osmolality

      Explanation:

      There are various medical conditions that can cause changes in urine and serum osmolality levels. Lithium is a common cause of acquired nephrogenic diabetes insipidus, which is characterized by low urine osmolality and high serum osmolality due to a deficiency in antidiuretic hormone secretion or poor kidney response to ADH. On the other hand, high blood sugar levels are associated with polyuria and polydipsia, which can be indicative of diabetes mellitus. Elevated serum calcium levels may be caused by hyperparathyroidism or vitamin D excess, which can also lead to polyuria and polydipsia. However, if the patient has a history of psychosis, psychogenic polydipsia may be the more likely cause. This condition is characterized by low urine and serum osmolality due to excessive water intake, often seen in middle-aged women with psychiatric comorbidities or after lesions in the hypothalamus affecting thirst centers. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is another disorder that can cause changes in urine and serum osmolality levels, characterized by high urine osmolality and low serum osmolality due to excessive ADH production.

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  • Question 32 - A 20-year old man with suspected schizophrenia is reviewed in clinic. During the...

    Correct

    • A 20-year old man with suspected schizophrenia is reviewed in clinic. During the consultation the patient informs you that there is a plot to destroy the world and that he has been chosen as a saviour.
      Which of the following terms most appropriately describes this patient's belief?

      Your Answer: Delusion

      Explanation:

      Understanding Psychotic Symptoms: Delusions, Illusions, Perseveration, and Hallucinations

      Psychotic symptoms are not simply exaggerations of normal experiences like anxiety or depression. They include hallucinations, delusions, and thought disorder. Delusions are false beliefs that are not shared by others in a cultural group and can be characteristic of different psychiatric disorders. Persecutory delusions are the most common form in schizophrenia and delusional disorder. Schizophrenia is characterized by episodes of delusions, hallucinations, bizarre behavior, incoherent thought processes, and flat or inappropriate affect. Illusions, on the other hand, are misinterpretations of existing sensory stimuli and suggest delirium or intoxication. Perseveration is the persistent repetition of words, phrases, or simple motor behavior and can occur in delirium, dementia, or psychosis. Hallucinations are perceptions of stimuli that are not there and are less common than delusions in schizophrenia. Mood-congruent delusions are consistent with the reported or observed mood and may be markers of the severity of mood disturbance, while mood-incongruent delusions are less easily explained but are commonly associated with a worse prognosis.

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  • Question 33 - A 35-year-old woman is experiencing a low mood after being laid off from...

    Incorrect

    • A 35-year-old woman is experiencing a low mood after being laid off from her job. She struggles to fall asleep at night and has difficulty getting out of bed in the morning. She has little desire to socialize with her friends or spend time with her family. She is consumed with anxiety about her future and has lost weight due to a decreased appetite.

      What are the primary symptoms of a depressive episode that she is experiencing?

      Your Answer: Depressed mood, disturbed sleep and diminished appetite

      Correct Answer: Depressed mood, anergia and anhedonia

      Explanation:

      Understanding the Symptoms of Depression

      Depression is a mental health condition that affects millions of people worldwide. It is characterized by a persistent feeling of sadness, hopelessness, and despair. The three core symptoms of depression are depressed mood, anhedonia, and anergia. To receive a diagnosis of depression, a person must have at least two of these core symptoms, as well as other non-core symptoms such as reduced concentration, disturbed sleep, and diminished appetite.

      While disturbed sleep and diminished appetite are common symptoms of depression, they are not considered core symptoms. On the other hand, overactivity and grandiose ideation are not typical symptoms of depression, as patients with depression usually have reduced activity and negative thoughts.

      Reduced self-esteem and self-confidence are also common in depression, but they are not considered core symptoms. In severe cases of depression, patients may experience catatonia and paranoid ideation, as well as other psychotic symptoms such as hallucinations and delusions.

      It is important to recognize the symptoms of depression and seek help if you or someone you know is struggling with this condition. With proper treatment, including therapy and medication, many people with depression can recover and lead fulfilling lives.

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      • Psychiatry
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  • Question 34 - A 27-year-old woman visits her General Practitioner for a follow-up appointment after being...

    Correct

    • A 27-year-old woman visits her General Practitioner for a follow-up appointment after being diagnosed with depression. She is currently undergoing treatment with citalopram and has started a course of cognitive behavioural therapy (CBT).
      What is used to assess the effectiveness of treatment in patients with depression?

      Your Answer: Patient Health Questionnaire (PHQ-9)

      Explanation:

      Common Screening Tools Used in Primary Care

      Primary care physicians often use various screening tools to assess their patients’ mental and physical health. Here are some of the most commonly used screening tools:

      1. Patient Health Questionnaire-9 (PHQ-9): This tool is used to monitor the severity of depression and the response to treatment.

      2. Mini-Mental State Examination (MMSE): This questionnaire is used to identify cognitive impairment and screen for dementia.

      3. Alcohol Use Disorders Identification Test (AUDIT): This screening tool is used to identify signs of harmful drinking and dependence on alcohol.

      4. Generalised Anxiety Disorder Questionnaire (GAD-7): This tool consists of seven questions and is used to screen for generalised anxiety disorder and measure the severity of symptoms.

      5. Modified Single-Answer Screening Question (M-SASQ): This is a single question alcohol harm assessment tool designed for use in Emergency Departments. It identifies high-risk drinkers based on the frequency of consuming six or more units (if female) or eight or more units (if male) on a single occasion in the last year.

      By using these screening tools, primary care physicians can identify potential health issues early on and provide appropriate treatment and care.

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      • Psychiatry
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  • Question 35 - A 42-year-old man is brought to the Emergency Department by his friends. He...

    Correct

    • A 42-year-old man is brought to the Emergency Department by his friends. He holds a senior trading job in an investment bank and has a history of recurrent admissions following cocaine intoxication. They are worried because he recently sent a memo to everyone on the trading floor suggesting that he is now the lead, he has the mental capacity to beat anyone to a higher profit and he should be chairman of the group. In fact, he has been performing poorly and has missed recent performance targets.
      Which of the following is the most likely diagnosis?

      Your Answer: Cocaine-induced delusional disorder

      Explanation:

      Understanding the Psychological Effects of Cocaine Use

      Cocaine use can lead to a range of psychological and psychiatric problems, including delusional disorder. This disorder is characterized by grandiose ideas concerning one’s social standing or intellectual ability, which are far in excess of reality. Cocaine-induced hallucinations are also common, particularly of the auditory or tactile variety.

      While some may mistake these symptoms for schizophrenia or a manic episode of bipolar disorder, it is important to consider the individual’s history of cocaine use. Cocaine intoxication can cause anxiety, agitation, euphoria, enlarged pupils, and palpitations, while severe intoxication can lead to delirium, hyperactivity, hyperthermia, and psychosis. Cocaine withdrawal, on the other hand, can cause fatigue, agitation, vivid and unpleasant dreams, increased appetite, and psychomotor retardation.

      Overall, it is crucial to understand the potential psychological effects of cocaine use and seek appropriate treatment if necessary.

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      • Psychiatry
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  • Question 36 - A 27-year-old man presents with a 6-month history of depressed mood. He reports...

    Correct

    • A 27-year-old man presents with a 6-month history of depressed mood. He reports feeling fatigued and having suicidal thoughts on a daily basis. His appearance is disheveled and he has made multiple suicide attempts in the past few months. The psychiatrist decides to initiate electroconvulsive therapy (ECT) for his depression, scheduled to begin in a week. The patient is currently taking 100 mg of sertraline daily. What is the appropriate course of action regarding his medication prior to ECT treatment?

      Your Answer: Reduce the sertraline daily dose

      Explanation:

      Before commencing ECT treatment, it is important to reduce the dosage of antidepressant medication, but not to stop it completely. The recommended approach is to gradually decrease the dosage to the minimum level. In some cases, an increased dosage of antidepressants may be added towards the end of the ECT course. It is not advisable to increase the dosage or discontinue the medication altogether. Switching to an alternative psychiatric drug, such as another SSRI or lithium, is also not recommended as it can be risky before ECT treatment.

      Electroconvulsive therapy (ECT) is a viable treatment option for patients who suffer from severe depression that does not respond to medication, such as catatonia, or those who experience psychotic symptoms. The only absolute contraindication for ECT is when a patient has raised intracranial pressure.

      Short-term side effects of ECT include headaches, nausea, short-term memory impairment, memory loss of events prior to the therapy, and cardiac arrhythmia. However, these side effects are typically temporary and resolve quickly.

      Long-term side effects of ECT are less common, but some patients have reported impaired memory. It is important to note that the benefits of ECT often outweigh the potential risks, and it can be a life-changing treatment for those who have not found relief from other forms of therapy.

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  • Question 37 - A 21-year-old woman is admitted to the psychiatric ward. She has been awake...

    Incorrect

    • A 21-year-old woman is admitted to the psychiatric ward. She has been awake for 4 days and is convinced that she will become the next big pop star by recording 3 albums simultaneously. When asked about her emotions, she immediately talks about her music projects, providing intricate details about each album, her plans for distribution, and her future as a famous musician. She then mentions that her mood has been fantastic because of these topics. When the conversation shifts, she continues to respond in a similar fashion. What term best describes this patient's presentation?

      Your Answer: Flight of ideas

      Correct Answer: Circumstantiality

      Explanation:

      Circumstantiality is the appropriate term to describe this patient’s response. They provide excessive and unnecessary detail before eventually answering the question about their mood. Flight of ideas, Knight’s move, and perseveration are not applicable in this case as the patient eventually returns to the original topic and follows along with subsequent topic changes.

      Thought disorders can manifest in various ways, including circumstantiality, tangentiality, neologisms, clang associations, word salad, Knight’s move thinking, flight of ideas, perseveration, and echolalia. Circumstantiality involves providing excessive and unnecessary detail when answering a question, but eventually returning to the original point. Tangentiality, on the other hand, refers to wandering from a topic without returning to it. Neologisms are newly formed words, often created by combining two existing words. Clang associations occur when ideas are related only by their similar sounds or rhymes. Word salad is a type of speech that is completely incoherent, with real words strung together into nonsensical sentences. Knight’s move thinking is a severe form of loosening of associations, characterized by unexpected and illogical leaps from one idea to another. Flight of ideas is a thought disorder that involves jumping from one topic to another, but with discernible links between them. Perseveration is the repetition of ideas or words despite attempts to change the topic. Finally, echolalia is the repetition of someone else’s speech, including the question that was asked.

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  • Question 38 - A 35-year-old man is brought to his GP by his partner who is...

    Correct

    • A 35-year-old man is brought to his GP by his partner who is concerned he may have developed bipolar disorder over the last few months.
      The man experiences periods of elevated mood, where he spends a lot of money and sleeps very little. He denies having any delusions of grandeur. These episodes usually last for a few days, and he has never put himself or others in danger.
      The man also has episodes of severe depression, where he feels suicidal, loses interest in his hobbies, and sleeps excessively. He is referred to a psychiatrist for further evaluation.
      What is the most probable diagnosis?

      Your Answer: Type 2 bipolar disorder

      Explanation:

      The woman’s alternating episodes of hypomania and severe depression suggest that she has type 2 bipolar disorder. There are no indications of an anxiety disorder, and the severity of her symptoms is not consistent with cyclothymia. Major depressive disorder is also not a likely diagnosis, as she experiences ‘highs’ consistent with hypomania. Type 1 bipolar disorder is also unlikely, as her ‘high’ periods are more in line with hypomania rather than full-blown mania.

      Understanding Bipolar Disorder

      Bipolar disorder is a mental health condition that is characterized by alternating periods of mania/hypomania and depression. It typically develops in the late teen years and has a lifetime prevalence of 2%. There are two recognized types of bipolar disorder: type I, which involves mania and depression, and type II, which involves hypomania and depression.

      Mania and hypomania both refer to abnormally elevated mood or irritability, but mania is more severe and can include psychotic symptoms for 7 days or more. Hypomania, on the other hand, involves decreased or increased function for 4 days or more. The presence of psychotic symptoms suggests mania.

      Management of bipolar disorder may involve psychological interventions specifically designed for the condition, as well as medication. Lithium is the mood stabilizer of choice, but valproate can also be used. Antipsychotic therapy, such as olanzapine or haloperidol, may be used to manage mania/hypomania, while fluoxetine is the antidepressant of choice for depression. It is important to address any co-morbidities, as there is an increased risk of diabetes, cardiovascular disease, and COPD in individuals with bipolar disorder.

      If symptoms suggest hypomania, routine referral to the community mental health team (CMHT) is recommended. However, if there are features of mania or severe depression, an urgent referral to the CMHT should be made. Understanding bipolar disorder and its management is crucial for healthcare professionals to provide appropriate care and support for individuals with this condition.

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      • Psychiatry
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  • Question 39 - A 45-year-old woman is brought in by her daughter because ‘she is acting...

    Correct

    • A 45-year-old woman is brought in by her daughter because ‘she is acting wild again’. She drinks moderately about once a week. She is not sleeping much, talks incessantly about plans to travel the world and has made many impulsive and irrational purchases. She reports hearing voices but refuses to discuss this issue when questioned by the admitting psychiatrist. She begins a task but does not complete it, all the while making lists of things to be done. She has been starting tasks and not finishing them. She had a similar episode 3 years ago. She also has depressive episodes several times over the last few years and recovered in between them.
      What is the most likely underlying diagnosis?

      Your Answer: Bipolar, manic, with mood-congruent psychotic features

      Explanation:

      Understanding Psychotic Disorders: Differential Diagnosis

      Psychotic disorders are a group of mental illnesses characterized by the presence of psychotic symptoms such as hallucinations, delusions, and disorganized thinking. However, differentiating between these disorders can be challenging. Here are some possible diagnoses for a patient presenting with manic and psychotic symptoms:

      Bipolar, manic, with mood-congruent psychotic features: This diagnosis is appropriate for a patient with both manic symptoms and mood-congruent psychotic features. The patient’s lack of insight is characteristic of either mania or psychosis. The need to get a history from a third party is typical. What distinguishes this from schizophrenia is that the patient appears to have a normal mood state.

      Substance-induced psychosis: The use of substances in this scenario is far too little to account for the patient’s symptoms, ruling out psychosis secondary to substance abuse.

      Schizophreniform disorder: This diagnosis is appropriate for a patient with symptoms of schizophrenia of <6 months' duration. Schizophrenia, paranoid type: This diagnosis is appropriate for a patient with symptoms for >6 months and multiple psychotic symptoms such as hallucinations, bizarre delusions, and social impairment.

      Schizoaffective disorder: This diagnosis is appropriate for a patient with both mood disorder and schizophrenic symptoms. However, the patient in this scenario is not expressing enough schizophrenic symptoms to establish a diagnosis of schizoaffective disorder.

      In conclusion, accurate diagnosis of psychotic disorders requires careful evaluation of the patient’s symptoms, history, and social functioning. A thorough understanding of the differential diagnosis is essential for effective treatment and management of these complex conditions.

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  • Question 40 - A 25-year-old man with type I diabetes mellitus visits his General Practitioner (GP)...

    Correct

    • A 25-year-old man with type I diabetes mellitus visits his General Practitioner (GP) with concerns about his deteriorating glycaemic control. The GP suspects poor compliance with diet and medication. What is the most effective approach to enhance his compliance during a brief consultation?

      Your Answer: Motivational interview

      Explanation:

      Effective Psychological Interventions in Primary Care

      Primary care settings are often the first point of contact for patients seeking help for mental health or physical conditions. To provide effective care, healthcare professionals can employ various psychological interventions. Here are some of the most effective ones:

      Motivational Interviewing: This patient-centred approach involves resisting a didactic course of action, understanding the reasons for the change in behaviour, listening to the patient’s ideas, concerns or expectations, and empowering the patient to understand they are able to change their behaviour. It has been proven to increase compliance with medication.

      Cognitive Behavioural Therapy (CBT): This talking therapy explores the patient’s understanding, concepts and reactions towards a certain problem, gradually building behavioural changes to challenge the concepts and manage the problem. It is used predominantly in the treatment of anxiety and depression, but can also be employed in many other mental health or physical conditions.

      Self-Help Materials: Self-help materials in the form of leaflets and aids are a useful tool in the primary care setting, but the patient needs to be motivated for change in order for these to work.

      Psychotherapy: This form of counselling employs various techniques to induce behavioural changes and habits that will stay with the patient in the long term. This requires a set amount of sessions over a period of time and therefore, cannot be performed in a short consultation.

      Supportive Counselling: This psychological intervention has been shown to be best suited for treating mild to moderate depression and can be used in combination with other methods such as CBT.

      By employing these psychological interventions, healthcare professionals can provide effective care for patients seeking help for mental health or physical conditions in primary care settings.

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      • Psychiatry
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Psychiatry (33/40) 83%
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