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  • Question 1 - A 32-year-old man with schizophrenia has been refusing to allow the mental health...

    Incorrect

    • A 32-year-old man with schizophrenia has been refusing to allow the mental health team to enter his residence, believing that they are secret agents. His mother is worried about his health and informs the team that he has not taken his medication for two weeks.
      What is the most suitable section of the mental health act to be utilized?

      Your Answer: 136

      Correct Answer: 135

      Explanation:

      Understanding Mental Health Detainment: A Guide to Sections 135, 4, 2, 3, and 136

      Mental health detainment can be a confusing and overwhelming process for both the individual in question and their loved ones. However, it is important to understand the different sections that can be used to detain a person for their own safety and the safety of others. Here is a breakdown of the most common sections used in mental health detainment:

      Section 135: This section allows the police to detain a person who is an immediate risk to themselves or others due to their mental health. The person can be moved to a safe area for assessment by a trained medical professional.

      Section 4: An emergency application for admission to hospital for up to 72 hours. This allows for an assessment by a doctor to determine if further detainment is necessary.

      Section 2: Used for assessment, this section allows for detainment for up to 28 days. If necessary, the responsible clinician can apply for a conversion to a section 3.

      Section 3: Detainment for up to six months, with the option for renewal if deemed necessary by the responsible clinician.

      Section 136: This section allows the police to detain a person in a public place who appears to have a mental health concern. The person can be moved to a safe location for assessment by a medical professional.

      Understanding these sections can help individuals and their loved ones navigate the mental health detainment process with more clarity and confidence.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 2 - A 50-year-old woman comes to you complaining of experiencing electric shock sensations and...

    Incorrect

    • A 50-year-old woman comes to you complaining of experiencing electric shock sensations and dizziness in her arms and legs for the past three days. She has a medical history of chronic pain, depression, and schizophrenia. When you inquire about her medications and drug use, she seems hesitant to provide a clear answer. What could be the probable reason behind her symptoms?

      Your Answer: Tricyclic overdose

      Correct Answer: SSRI discontinuation syndrome

      Explanation:

      If someone suddenly stops or reduces their use of SSRIs, they may experience symptoms of SSRI discontinuation syndrome, including dizziness, electric shock sensations, and anxiety. It is possible that this woman has decided to stop taking her antidepressants. Symptoms of alcohol withdrawal typically include anxiety, tremors, and sweating. Neuroleptic malignant syndrome is a rare reaction that can occur with antipsychotic use and may present with fever, confusion, and muscle rigidity. Opiate withdrawal may cause anxiety, sweating, and gastrointestinal symptoms such as diarrhea and vomiting.

      Selective serotonin reuptake inhibitors (SSRIs) are commonly used as the first-line treatment for depression. Citalopram and fluoxetine are the preferred SSRIs, while sertraline is recommended for patients who have had a myocardial infarction. However, caution should be exercised when prescribing SSRIs to children and adolescents. Gastrointestinal symptoms are the most common side-effect, and patients taking SSRIs are at an increased risk of gastrointestinal bleeding. Patients should also be aware of the possibility of increased anxiety and agitation after starting a SSRI. Fluoxetine and paroxetine have a higher propensity for drug interactions.

      The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a warning regarding the use of citalopram due to its association with dose-dependent QT interval prolongation. As a result, citalopram and escitalopram should not be used in patients with congenital long QT syndrome, known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval. The maximum daily dose of citalopram is now 40 mg for adults, 20 mg for patients older than 65 years, and 20 mg for those with hepatic impairment.

      When initiating antidepressant therapy, patients should be reviewed by a doctor after 2 weeks. Patients under the age of 25 years or at an increased risk of suicide should be reviewed after 1 week. If a patient responds well to antidepressant therapy, they should continue treatment for at least 6 months after remission to reduce the risk of relapse. When stopping a SSRI, the dose should be gradually reduced over a 4 week period, except for fluoxetine. Paroxetine has a higher incidence of discontinuation symptoms, including mood changes, restlessness, difficulty sleeping, unsteadiness, sweating, gastrointestinal symptoms, and paraesthesia.

      When considering the use of SSRIs during pregnancy, the benefits and risks should be weighed. Use during the first trimester may increase the risk of congenital heart defects, while use during the third trimester can result in persistent pulmonary hypertension of the newborn. Paroxetine has an increased risk of congenital malformations, particularly in the first trimester.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 3 - A 25-year-old woman who is a law student has severe anxiety about public...

    Correct

    • A 25-year-old woman who is a law student has severe anxiety about public speaking and in informal social settings. She avoids situations where she might have to enter into conversations with strangers. She reports that she thinks others are frustrated by her inability in casual social interactions and that she ‘feels stupid and awkward’. Her social problems are also affecting her academic performance. She is considering leaving university for a less stressful environment.
      Which is the most appropriate form of psychotherapy for this woman?

      Your Answer: Cognitive behavioural therapy

      Explanation:

      Choosing the Right Treatment for Social Phobia: Cognitive Behavioural Therapy

      Social phobia is a type of anxiety disorder that can cause panic and avoidance of social situations. For patients with this condition, cognitive behavioural therapy (CBT) is often the best treatment option. CBT can help patients identify and change negative thought patterns that contribute to their anxiety, and it often includes exposure therapy as a component.

      Other treatment options, such as vocational counselling or psychoanalytic psychotherapy, may not be as effective for social phobia. Suggesting these options could reinforce the patient’s belief that their symptoms cannot be treated therapeutically. Network therapy is designed for substance abusers, and self-help groups may be helpful for some patients, but only if they can manage their anxiety enough to participate effectively.

      In summary, for patients with social phobia, cognitive behavioural therapy is the most effective treatment option. It can help patients overcome their anxiety and improve their quality of life.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 4 - Sarah, a 15-year-old girl is brought to the GP by her father as...

    Correct

    • Sarah, a 15-year-old girl is brought to the GP by her father as Sarah has not had her first period. She is 1.50m tall and weighs 40 Kg. Her heart rate is 60 beats per minute. Blood pressure is 120/90 mmHg. She has not developed any secondary sexual characteristics. There is a strong family history of eating disorder. You suspect that the delayed puberty may be due to anorexia nervosa.
      What evidence supports the diagnosis of anorexia nervosa in Sarah?

      Your Answer: Lanugo hair

      Explanation:

      The presence of lanugo hair, which is fine and downy hair that grows in response to body fat loss, can be a characteristic physical finding that supports the diagnosis of anorexia nervosa. However, this should be considered alongside other features such as the failure of secondary sexual characteristics, bradycardia, cold intolerance, and a yellow tinge on the skin (hypercarotenaemia). Anosmia is not typically associated with anorexia nervosa, but it may be relevant in patients with Kallmann syndrome, which involves anosmia and delayed or absent puberty. Hirsutism, which is excessive hair growth, is indicative of elevated testosterone levels and is not compatible with anorexia nervosa. Hyperkalaemia is an incorrect feature, as hypokalaemia is the most common electrolyte abnormality in anorexia. Patients with anorexia nervosa often have high cholesterol levels in their blood.

      Characteristics of Anorexia Nervosa

      Anorexia nervosa is a disorder that is characterized by a number of clinical signs and physiological abnormalities. The most notable feature of this disorder is a reduced body mass index, which is often accompanied by bradycardia and hypotension. In addition, individuals with anorexia nervosa may experience enlarged salivary glands, which can cause discomfort and difficulty swallowing.

      Physiological abnormalities associated with anorexia nervosa include hypokalaemia, which is a deficiency of potassium in the blood, as well as low levels of FSH, LH, oestrogens, and testosterone. Individuals with anorexia nervosa may also have raised levels of cortisol and growth hormone, impaired glucose tolerance, hypercholesterolaemia, hypercarotinaemia, and low T3.

      Overall, anorexia nervosa is a complex disorder that can have a significant impact on an individual’s physical and emotional well-being. It is important for individuals who are struggling with this disorder to seek professional help in order to receive the support and treatment they need to recover.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 5 - A 25-year-old female complains of headache, weakness, and pains in her arms and...

    Incorrect

    • A 25-year-old female complains of headache, weakness, and pains in her arms and legs. She reports feeling like her symptoms are worsening. She has no significant medical history except for a miscarriage two years ago.

      Upon examination, her neurological and musculoskeletal functions appear normal, and there are no alarming signs in her headache history. Her GP conducts a comprehensive blood test, which yields normal results.

      What is the most probable diagnosis for this patient?

      Your Answer: Münchhausen syndrome

      Correct Answer: Somatoform disorder

      Explanation:

      The young woman has physical symptoms without any disease process, which may be a form of somatisation/somatoform disorder. This disorder is often caused by underlying psychological distress and may result in depression or anxiety. Hypochondriasis is a belief that one is suffering from a severe disorder, while Münchausen syndrome is a disorder where a patient mimics a particular disorder to gain attention. To diagnose malingering, there needs to be evidence that the patient is purposefully generating symptoms for some kind of gain. In a somatisation disorder, the patient may have no clinical evidence of illness or physical injury but believes they have one.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 6 - A 25-year-old man is worried about several recent incidents related to his sleep....

    Correct

    • A 25-year-old man is worried about several recent incidents related to his sleep. He reports experiencing paralysis upon waking up and occasionally when falling asleep, accompanied by what he describes as 'hallucinations' such as seeing another person in the room. These episodes are causing him increasing anxiety. What is the probable diagnosis?

      Your Answer: Sleep paralysis

      Explanation:

      Understanding Sleep Paralysis

      Sleep paralysis is a condition that affects many people and is characterized by a temporary inability to move the skeletal muscles when waking up or falling asleep. It is believed to be linked to the natural paralysis that occurs during REM sleep. This phenomenon is recognized in various cultures and is often accompanied by hallucinations or vivid images.

      The paralysis occurs either before falling asleep or after waking up, and it can be a frightening experience for those who are not familiar with it. However, it is a relatively harmless condition that does not require medical attention in most cases. If the symptoms are particularly bothersome, medication such as clonazepam may be prescribed to alleviate the symptoms.

      In summary, sleep paralysis is a common occurrence that affects many people. It is characterized by temporary paralysis of the skeletal muscles and is often accompanied by hallucinations. While it can be a frightening experience, it is generally harmless and does not require medical attention.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 7 - A 30-year-old bipolar woman has been readmitted to the hospital after attempting to...

    Correct

    • A 30-year-old bipolar woman has been readmitted to the hospital after attempting to harm herself. She is currently stable. What form of psychotherapy would be most appropriate in this case?

      Your Answer: Cognitive behavioural therapy

      Explanation:

      Psychotherapy Options for Schizophrenia

      There are several psychotherapy options available for individuals with schizophrenia. Cognitive behavioural therapy (CBT) is a structured, goal-directed, problem-focused, and time-limited therapy that combines principles of both behavioural and cognitive therapy. It focuses on the environment, behaviour, and cognition simultaneously. Brief psychodynamic psychotherapy primarily relies on insight, bringing unconscious or unclear material into awareness, and linking past and present experiences to address the patient’s difficulties. Interpersonal therapy is derived partially from a psychodynamic perspective and focuses primarily on the patient’s interpersonal relationships. It is fairly non-directive and addresses issues such as grief, role transitions, interpersonal role disputes, and interpersonal deficits as they relate to the patient’s current symptoms.

      Family therapy is another option that helps family members learn about the disorder, solve problems, and cope more constructively with the patient’s illness. There is evidence that family interventions can reduce relapse rates in schizophrenia. Systemic desensitisation is an exposure-based behavioural treatment that utilises gradual, systematic, repeated exposure to the feared object or situation to allow patients with anxiety disorders to become desensitised to the feared stimulus.

      The decision between CBT and family therapy would be highly influenced by patient preference. However, if only CBT is presented as an option, it would be the appropriate choice. It is important to consider the different psychotherapy options available and choose the one that best suits the patient’s needs and preferences.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 8 - A young adult is concerned about her ability to take her upcoming final...

    Correct

    • A young adult is concerned about her ability to take her upcoming final exams at university in three months. She experiences feelings of fluster, faintness, and dizziness specifically during written exams, but has no symptoms at any other time, including during physical activity. Her resting ECG is normal and clinical examination shows no abnormalities. What is the best course of action to take?

      Your Answer: Arrange counselling, with relaxation training

      Explanation:

      a Student’s Symptoms of Stress and Anxiety

      The symptoms described by the student are typical of stress and anxiety, which are common experiences for many people. It is important to reassure the student that these symptoms do not necessarily indicate an underlying medical condition. However, if the student is concerned, a 24-hour ECG monitoring can be done to provide further reassurance.

      It is important to note that prescribing diazepam may not be the best course of action as it can impair the student’s exam performance. Similarly, fluoxetine may not be the best option as it can increase feelings of anxiety. It is important to consider alternative treatments that can help the student manage their stress and anxiety in a way that does not negatively impact their academic performance. By the student’s symptoms and providing appropriate support, we can help them navigate this challenging time and achieve their academic goals.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 9 - A client under your care has been prescribed imipramine for depression. What combination...

    Incorrect

    • A client under your care has been prescribed imipramine for depression. What combination of side-effects is most probable in an individual taking this type of antidepressant?

      Your Answer: Gastrointestinal bleeding + dyspepsia

      Correct Answer: Blurred vision + dry mouth

      Explanation:

      Tricyclic Antidepressants for Neuropathic Pain

      Tricyclic antidepressants (TCAs) were once commonly used for depression, but their side-effects and toxicity in overdose have led to a decrease in their use. However, they are still widely used in the treatment of neuropathic pain, where smaller doses are typically required. TCAs such as low-dose amitriptyline are commonly used for the management of neuropathic pain and the prophylaxis of headache, while lofepramine has a lower incidence of toxicity in overdose. It is important to note that some TCAs, such as amitriptyline and dosulepin, are considered more dangerous in overdose than others.

      Common side-effects of TCAs include drowsiness, dry mouth, blurred vision, constipation, urinary retention, and lengthening of the QT interval. When choosing a TCA for neuropathic pain, the level of sedation may also be a consideration. Amitriptyline, clomipramine, dosulepin, and trazodone are more sedative, while imipramine, lofepramine, and nortriptyline are less sedative. It is important to work with a healthcare provider to determine the appropriate TCA and dosage for the individual’s specific needs.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 10 - A 36-year-old man is brought to the Emergency Mental Health Ward. He is...

    Correct

    • A 36-year-old man is brought to the Emergency Mental Health Ward. He is speaking rapidly, claiming to be the ‘new Messiah’ and insisting that he has the ability to cure acquired immune deficiency syndrome (AIDS) with the assistance of his friends who are providing him with undisclosed 'classified' knowledge.
      What medication would be appropriate to administer to this individual?

      Your Answer: Olanzapine

      Explanation:

      Choosing the Right Medication for Psychosis: A Comparison of Olanzapine, Diazepam, Citalopram, Clozapine, and Zopiclone

      When a patient presents with psychosis, it is crucial to assess them urgently and rule out any organic medical causes. The primary treatment for psychosis is antipsychotics, such as olanzapine. While benzodiazepines like diazepam can be used to treat agitation associated with acute psychosis, they are not the first-line treatment. Citalopram, a selective serotonin reuptake inhibitor used for depression, would not be appropriate for treating psychosis. Clozapine, another antipsychotic, is only used on specialist advice due to the risk of agranulocytosis. Zopiclone, a hypnotic used for sleep, is not appropriate for treating psychosis. It is important to choose the right medication for psychosis to ensure the best possible outcome for the patient.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 11 - A 26-year-old man presents to your clinic six months after he was assaulted...

    Incorrect

    • A 26-year-old man presents to your clinic six months after he was assaulted on his way home from work. He was mugged and punched in the stomach by his attacker before he fled. Six months later, the patient continues to have severe and incapacitating periumbilical pain where he was punched. He denies any gastrointestinal symptoms or any other issues. Previous investigations and imaging have been unremarkable for any underlying anatomical, neurological or vascular abnormality.
      What is the most appropriate description of the patient's current complaints during the clinic visit?

      Your Answer: Post-traumatic stress disorder (PTSD)

      Correct Answer: Pain disorder

      Explanation:

      Differentiating between Psychiatric Disorders: Pain Disorder, Conversion Disorder, Somatization Disorder, PTSD, and Acute Stress Disorder

      When evaluating a patient with unexplained physical symptoms, it is important to consider various psychiatric disorders that may be contributing to their presentation. In this case, the patient’s symptoms do not fit the criteria for somatization disorder, PTSD, or acute stress disorder. However, there are other disorders that should be considered.

      Pain disorder is characterized by intense, long-standing pain without a somatic explanation. The patient’s pain is out of proportion to the injury and is not explained by any underlying somatic pathology. This disorder is restricted to physical pain and does not include other somatic complaints.

      Conversion disorder, on the other hand, presents as a neurological deficit in the absence of a somatic cause. Patients are usually unconcerned about the symptom, unlike this patient. It usually follows a psychosocial stressor.

      Somatization disorder refers to patients with a constellation of physical complaints that are not explained by a somatic process. This would include odd distributions of pain, numbness, GI upset, headache, nausea, vomiting, shortness of breath, palpitations, etc. However, this patient is fixated on a particular disease and does not fit the criteria for somatization.

      PTSD presents with persistent re-experiencing of the trauma, nightmares, flashbacks, intense fear, avoidant behaviour and/or increased arousal. Symptoms must persist for at least 1 month and impair his quality of life. There are no clear signs of PTSD in this patient.

      Acute stress disorder is an anxiety condition precipitated by an acute stress that resolves within a month. This is well beyond the window for acute stress, and it does not fit the symptomatology of acute stress.

      In conclusion, it is important to consider various psychiatric disorders when evaluating a patient with unexplained physical symptoms. By ruling out certain disorders, a proper diagnosis and treatment plan can be established.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 12 - A 35-year-old man who is an accountant presents with complaints of fainting spells,...

    Correct

    • A 35-year-old man who is an accountant presents with complaints of fainting spells, dizziness, palpitations and pressure in his chest. He experiences these symptoms for 5-10 minutes during which he becomes anxious about fainting and dying. He takes a longer route to work to avoid crossing busy streets as he fears getting hit by a car if he faints. He avoids public speaking and works late into the night from home, which exacerbates his symptoms. What is the probable diagnosis?

      Your Answer: Panic disorder with agoraphobia

      Explanation:

      Differentiating Panic Disorder from Other Conditions

      Panic disorder is a mental health condition characterized by intense anxiety episodes with somatic symptoms and an exaggerated sense of danger. However, it can be challenging to distinguish panic disorder from other conditions that share similar symptoms. Here are some examples:

      Panic Disorder vs. Somatisation Disorder

      Patients with somatisation disorder also experience physical symptoms, but they fall into four different clusters: pain, gastrointestinal, urogenital, and neurological dysfunction. In contrast, panic disorder symptoms are more generalized and not limited to specific bodily functions.

      Panic Disorder vs. Hypoglycemia

      Hypoglycemia rarely induces severe panic or anticipatory anxiety, except in cases of insulin reactions. Patients with hypoglycemia typically experience symptoms such as sweating and hunger, which are not necessarily associated with panic disorder.

      Panic Disorder vs. Paroxysmal Atrial Tachycardia

      Paroxysmal atrial tachycardia is a heart condition that causes a doubling of the pulse rate and requires electrocardiographic evidence for diagnosis. While it may cause some anxiety, it is not typically accompanied by the intense subjective anxiety seen in panic disorder.

      Panic Disorder vs. Specific Phobia

      Specific phobias involve reactions to limited cues or situations, such as spiders, blood, or needles. While they may trigger panic attacks and avoidance, they are not as generalized as panic disorder and are limited to specific feared situations.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 13 - A 20-year-old man with moderate learning difficulty visits your clinic with his father....

    Incorrect

    • A 20-year-old man with moderate learning difficulty visits your clinic with his father. His father complains that he has trouble sleeping at night and frequently wakes up, disrupting his own sleep and causing him to be excessively drowsy during the day. He frequently takes a nap in the late afternoon, which is impacting his ability to participate in local community services. They have already attempted conventional sleep hygiene recommendations. Given the history of learning difficulty, what would be the most appropriate medication to assist with his sleep problems?

      Your Answer: Zopiclone

      Correct Answer: Melatonin

      Explanation:

      Medication Options for Sleep Disturbance in Patients with Learning Disabilities

      Patients with learning disabilities often experience chronic sleep-wake cycle disruption, leading to insomnia. Melatonin has been found to be effective in regulating natural sleep-wake cycles and treating insomnia in these patients. However, it is not licensed for use in individuals under 55 years old and should only be prescribed by a psychiatrist with expertise in sleep disturbance in learning disability.

      Other medications, such as zopiclone, diazepam, promethazine, and trazodone, can also be used for insomnia. Zopiclone is helpful for patients with trouble falling asleep, while diazepam can be used for anxiety and sedation but may lead to dependence. Promethazine is useful for maintaining sleep, particularly in cases of agitation or insomnia. Trazodone, on the other hand, is an antidepressant medication with sedating properties and is typically used for patients with depression and sleep disturbance.

      However, given the history of learning disability in the stem, melatonin would be the most appropriate medication to trial in this patient. It is important to consult with a psychiatrist with expertise in sleep disturbance in learning disability to determine the best course of treatment.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 14 - You are part of the mental health team assessing a 65-year-old woman in...

    Correct

    • You are part of the mental health team assessing a 65-year-old woman in the emergency department who has presented with an intentional paracetamol overdose. She is a retired teacher and a devout Christian. She lives alone in a house and her two adult daughters live in a different state. When you ask her, she says that she regrets taking the paracetamol, but is not sure if she would try to do it again.

      What factor decreases her likelihood of carrying out another attempt in the future?

      Your Answer: His religious beliefs

      Explanation:

      Protective factors against completed suicide include religious beliefs, social support, regretting a previous attempt, and having children living at home. However, older age, male gender, and lack of social support are risk factors for suicide. While women are more likely to attempt suicide, men are more likely to die by suicide, possibly due to stigma and different suicide methods. In the case of the individual mentioned, his children living far away may increase his risk of suicide due to a lack of social support.

      Suicide Risk Factors and Protective Factors

      Suicide risk assessment is a common practice in psychiatric care, with patients being stratified into high, medium, or low risk categories. However, there is a lack of evidence on the positive predictive value of individual risk factors. A review in the BMJ concluded that such assessments may not be useful in guiding decision-making, as 50% of suicides occur in patients deemed low risk. Nevertheless, certain factors have been associated with an increased risk of suicide, including male sex, history of deliberate self-harm, alcohol or drug misuse, mental illness, depression, schizophrenia, chronic disease, advancing age, unemployment or social isolation, and being unmarried, divorced, or widowed.

      If a patient has attempted suicide, there are additional risk factors to consider, such as efforts to avoid discovery, planning, leaving a written note, final acts such as sorting out finances, and using a violent method. On the other hand, there are protective factors that can reduce the risk of suicide, such as family support, having children at home, and religious belief. It is important to consider both risk and protective factors when assessing suicide risk and developing a treatment plan.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 15 - A 49-year-old man is brought to the emergency department after being found wandering...

    Incorrect

    • A 49-year-old man is brought to the emergency department after being found wandering the streets in an agitated state. His medical history includes hepatic steatosis, hypertension, and asthma, and he regularly takes amlodipine and Symbicort. He drinks up to 1 liter of vodka daily and has smoked for 30 years. He has not been seen by his family for 2-3 days before these events. His vital signs are heart rate 111 beats per minute, blood pressure 170/94 mmHg, respiratory rate 23 /min, oxygen saturations 97% on air, and temperature 37.2ºC. He is tremulous, diaphoretic, and agitated. Shortly after examination, he has a self-terminating seizure lasting 30 seconds. Blood tests and a CT head are performed, with the latter being reported as normal. What is the best medication choice to prevent further seizures?

      Your Answer: Intravenous pabrinex

      Correct Answer: Oral chlordiazepoxide

      Explanation:

      Chlordiazepoxide is the preferred medication for treating delirium tremens and alcohol withdrawal, not diazepam. Symptoms of minor alcohol withdrawal, such as tremors, anxiety, and headaches, typically appear 6-12 hours after alcohol cessation and can progress to alcoholic hallucinosis, withdrawal seizures, and delirium tremens. Delirium tremens and alcohol withdrawal seizures are treated with chlordiazepoxide as the first-line medication. The Clinical Institute Withdrawal Assessment for Alcohol (CIWA) score is used to manage alcohol withdrawal in hospital, with benzodiazepines being administered based on the score. Intravenous glucose, intravenous hypertonic saline, and intravenous levetiracetam are not appropriate treatments for delirium tremens and alcohol withdrawal.

      Alcohol withdrawal occurs when an individual who has been consuming alcohol chronically suddenly stops or reduces their intake. Chronic alcohol consumption enhances the inhibitory effects of GABA in the central nervous system, similar to benzodiazepines, and inhibits NMDA-type glutamate receptors. However, alcohol withdrawal leads to the opposite effect, resulting in decreased inhibitory GABA and increased NMDA glutamate transmission. Symptoms of alcohol withdrawal typically start at 6-12 hours and include tremors, sweating, tachycardia, and anxiety. Seizures are most likely to occur at 36 hours, while delirium tremens, which includes coarse tremors, confusion, delusions, auditory and visual hallucinations, fever, and tachycardia, peak at 48-72 hours.

      Patients with a history of complex withdrawals from alcohol, such as delirium tremens, seizures, or blackouts, should be admitted to the hospital for monitoring until their withdrawals stabilize. The first-line treatment for alcohol withdrawal is long-acting benzodiazepines, such as chlordiazepoxide or diazepam, which are typically given as part of a reducing dose protocol. Lorazepam may be preferable in patients with hepatic failure. Carbamazepine is also effective in treating alcohol withdrawal, while phenytoin is said to be less effective in treating alcohol withdrawal seizures.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 16 - A 68-year-old woman visits her GP and complains of constant worrying, difficulty sleeping,...

    Correct

    • A 68-year-old woman visits her GP and complains of constant worrying, difficulty sleeping, and lack of focus on activities she used to enjoy. She is prescribed a new medication and referred for CBT. After a month, she returns to her GP feeling weak, lethargic, and experiencing muscle cramps. Her blood tests reveal the following results:
      Sodium: 126 mmol/l (normal range: 135-145 mmol/l)
      Potassium: 3.7 mmol/l (normal range: 3.5-5.0 mmol/l)
      Creatinine: 95 µmol/l (normal range: 68-98 µmol/l)
      Calcium: 2.40 mmol/l (normal range: 2.05-2.60 mmol/l)
      Phosphate: 1.41 mmol/l (normal range: 0.8-1.50 mmol/l)
      Which medication is most likely responsible for her symptoms?

      Your Answer: Sertraline

      Explanation:

      Common Anxiety Medications and their Side Effects

      Anxiety disorders are commonly treated with medication, and there are several options available. The first-line pharmacological treatment for anxiety is selective serotonin reuptake inhibitors (SSRIs) such as sertraline, paroxetine, or escitalopram. Alternatively, serotonin and norepinephrine reuptake inhibitors (SNRIs) like venlafaxine or duloxetine may be used. However, it is important to note that SSRIs can cause hyponatraemia, particularly in the elderly.

      Diazepam is another medication used to treat anxiety, but it is not known to cause hyponatraemia. Its main side-effects are drowsiness and decreased concentration.

      Pregabalin may be used if SSRIs or SNRIs are contraindicated or cannot be tolerated. It is not known to cause hyponatraemia.

      Propranolol is a medication commonly used to treat high blood pressure, but it can also be used to treat anxiety. Its main side-effects are dizziness, fatigue, cold peripheries, insomnia, and nightmares. However, hyponatraemia is not a known side-effect of propranolol.

      Finally, zopiclone may be prescribed for insomnia, but it is usually a short-term prescription and not given for more than four weeks due to the risk of withdrawal symptoms and tolerance. It is not known to cause hyponatraemia.

      In summary, while there are several medications available to treat anxiety, it is important to be aware of their potential side-effects and to discuss any concerns with a healthcare provider.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 17 - An 87-year-old man who lives in a care home is reported missing after...

    Correct

    • An 87-year-old man who lives in a care home is reported missing after breakfast. The care home actively tries to find him but is not able to for the next few hours. A police report is made, and later that day, the man is found wandering two streets away from the care home. He is brought back to the care home, and the care home is concerned that he might try to get out again. The nurse caring for the patient reports that the man has been trying to get out of the care home for the past few weeks but did not manage to do so, as they were able to prevent him on time. The care home wants to fit a lock to the patient’s room door to restrict his mobility during busy times of the day when limited staff are available to make sure he does not get out. The patient is medically stable, has a diagnosis of dementia, and is known to lack capacity to make a decision about his treatment and freedom.
      Which of the following is the best course of action for this patient?

      Your Answer: The patient can be restricted for seven days under urgent DoLS authorisation

      Explanation:

      Understanding Urgent DoLS Authorisation

      In situations where a person’s best interest requires the authorisation of Deprivation of Liberty Safeguards (DoLS) but there is not enough time for a standard authorisation, an urgent authorisation can be applied for by the care home manager or hospital. This allows the individual to be deprived of their liberty for up to seven days. It is important to note that this can only be done if it is in the person’s best interest.

      In the case of a patient who lacks capacity, they cannot make decisions regarding their freedom and treatment. Therefore, the option of allowing the patient to be free is not applicable. However, if the patient is medically stable and does not require hospital admission, they should not be admitted.

      It is crucial to understand that an urgent DoLS authorisation can only be applied for seven days, not 21 days. Additionally, the Mental Health Act 1983 is not appropriate for detaining patients who are not in the hospital for assessment or treatment.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 18 - A 21-year-old man is brought to the psychiatrist by his father. He expresses...

    Incorrect

    • A 21-year-old man is brought to the psychiatrist by his father. He expresses concern for his son's mental health, as he has noticed him talking to himself frequently over the past 6 months. The patient is hesitant to speak with the psychiatrist and insists that his father stay in the room with him. During the psychiatric evaluation, it is revealed that the patient has been hearing a voice in his head for the past year, but denies any thoughts of self-harm or harm to others. The psychiatrist recommends a referral for further treatment, which causes the father to become emotional and question if he did something wrong as a parent. Which factor from the patient's history is a poor prognostic indicator for his condition?

      Your Answer: Sudden onset

      Correct Answer: Pre-morbid social withdrawal

      Explanation:

      Schizophrenia is more likely to be diagnosed if the patient presents with Schneider’s first-rank symptoms, such as auditory hallucinations, which are characteristic of the condition. However, the presence of auditory hallucinations alone does not indicate a poor prognosis. A poor prognosis is associated with pre-morbid social withdrawal, low IQ, family history of schizophrenia, gradual onset of symptoms, and lack of an obvious precipitant. There is no known link between a family history of an eating disorder and a poor prognosis in schizophrenia.

      Schizophrenia is a mental disorder that can have varying prognosis depending on certain factors. Some indicators associated with a poor prognosis include a strong family history of the disorder, a gradual onset of symptoms, a low IQ, a prodromal phase of social withdrawal, and a lack of an obvious precipitant. These factors can contribute to a more severe and chronic course of the illness, making it more difficult to manage and treat. It is important for individuals with schizophrenia and their loved ones to be aware of these indicators and seek appropriate treatment and support.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 19 - A 32-year-old man visits his General Practitioner (GP) for an annual mental health...

    Correct

    • A 32-year-old man visits his General Practitioner (GP) for an annual mental health review. He was diagnosed with schizophrenia eight years ago. He has been on medication since diagnosis and takes this daily without any side-effects. He has regular contact with the community mental health team. He is working part-time as a shop assistant, which he enjoys. He has a good appetite, sleeps well and exercises regularly.

      What is true regarding the treatment of schizophrenia in a 32-year-old man who has been diagnosed with the condition for eight years and is currently on medication without any side-effects, has regular contact with the community mental health team, works part-time, and has good appetite, sleep, and exercise habits?

      Your Answer: People with a first episode of psychosis should be offered oral antipsychotic treatment, along with psychological interventions

      Explanation:

      Mythbusting: Common Misconceptions About Schizophrenia Treatment

      1. Oral antipsychotic treatment and psychological interventions should be offered to those with a first episode of psychosis.
      2. Patients with schizophrenia should remain under the care of a psychiatrist lifelong, but can be eligible for shared care with a GP after 12 months of stability.
      3. An ECG is only necessary before starting antipsychotic medication in certain circumstances.
      4. Before starting any oral antipsychotic medication, various health factors need to be checked in all patients.
      5. The choice of antipsychotic medication should be made on an individual basis, taking into account potential side-effects.
      6. Early intervention in psychosis services should be accessed urgently for anyone presenting with a first episode of psychosis. Antipsychotic medication should not be initiated in primary care without the advice of a psychiatrist.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 20 - A 29-year-old man presented to the hospital, accompanied by the police after having...

    Correct

    • A 29-year-old man presented to the hospital, accompanied by the police after having had a fight in a casino. The casino manager called the police when the man refused to leave after he had spent almost 24 hours gambling. The patient ran out of money and was harassing other clients, trying to borrow money from them and telling them that he will return it after he had won and invested the prize money. The patient has no known next of kin and refuses to engage with the attending doctor. He threatens to assault the medical staff and is eventually put under urgent mental health Section 4. A review of his medical notes reveals that the only medication on which he has been is lithium for a known psychiatric illness, but he has not been in touch with his general practitioner for the past two months.
      What is the best course of action for managing this patient?

      Your Answer: Check the lithium levels and consider adding olanzapine

      Explanation:

      Management of Bipolar Depression with Mania or Hypomania

      According to the latest NICE guideline CG85, patients with bipolar depression presenting with mania or hypomania should have their lithium levels checked and consider adding an antipsychotic such as haloperidol, olanzapine, quetiapine or risperidone. Therefore, checking the lithium levels and considering adding olanzapine is the correct answer in this case.

      Stopping lithium without checking the levels first is not recommended as it is a mood stabiliser and may be required for the patient. Starting haloperidol or risperidone without checking the lithium levels is also not recommended as the doctor must consider the patient’s lithium levels before adding an antipsychotic.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 21 - A 42-year-old man is brought to the Emergency Department by his friends. He...

    Correct

    • A 42-year-old man is brought to the Emergency Department by his friends. He holds a senior trading job in an investment bank and has a history of recurrent admissions following cocaine intoxication. They are worried because he recently sent a memo to everyone on the trading floor suggesting that he is now the lead, he has the mental capacity to beat anyone to a higher profit and he should be chairman of the group. In fact, he has been performing poorly and has missed recent performance targets.
      Which of the following is the most likely diagnosis?

      Your Answer: Cocaine-induced delusional disorder

      Explanation:

      Understanding the Psychological Effects of Cocaine Use

      Cocaine use can lead to a range of psychological and psychiatric problems, including delusional disorder. This disorder is characterized by grandiose ideas concerning one’s social standing or intellectual ability, which are far in excess of reality. Cocaine-induced hallucinations are also common, particularly of the auditory or tactile variety.

      While some may mistake these symptoms for schizophrenia or a manic episode of bipolar disorder, it is important to consider the individual’s history of cocaine use. Cocaine intoxication can cause anxiety, agitation, euphoria, enlarged pupils, and palpitations, while severe intoxication can lead to delirium, hyperactivity, hyperthermia, and psychosis. Cocaine withdrawal, on the other hand, can cause fatigue, agitation, vivid and unpleasant dreams, increased appetite, and psychomotor retardation.

      Overall, it is crucial to understand the potential psychological effects of cocaine use and seek appropriate treatment if necessary.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 22 - A 26-year-old male comes to his doctor's office at the request of his...

    Correct

    • A 26-year-old male comes to his doctor's office at the request of his friends. Upon examination, he discloses that he thinks everyone can hear his thoughts, as if he were a radio station, and that he hears voices commenting on his actions. The doctor observes that he has a blunted affect, alogia, and avolition. Additionally, the doctor notes that the patient repeats the final word of any inquiry posed to him.

      What term describes this phenomenon?

      Your Answer: Echolalia

      Explanation:

      Echolalia is when someone repeats the speech of another person, including any questions asked. This is often seen in individuals with schizophrenia, particularly catatonic schizophrenia, which is characterized by negative symptoms such as a lack of emotional expression, poverty of speech, and poor motivation. The patient in question exhibits two of Schneider’s first-rank symptoms: thought broadcasting and third-person auditory hallucinations, and is therefore diagnosable with schizophrenia. Copropraxia refers to the involuntary performance of obscene or forbidden gestures or inappropriate touching, while echopraxia involves the meaningless repetition or imitation of others’ movements. Finally, a neologism is a word that has been made up.

      Thought disorders can manifest in various ways, including circumstantiality, tangentiality, neologisms, clang associations, word salad, Knight’s move thinking, flight of ideas, perseveration, and echolalia. Circumstantiality involves providing excessive and unnecessary detail when answering a question, but eventually returning to the original point. Tangentiality, on the other hand, refers to wandering from a topic without returning to it. Neologisms are newly formed words, often created by combining two existing words. Clang associations occur when ideas are related only by their similar sounds or rhymes. Word salad is a type of speech that is completely incoherent, with real words strung together into nonsensical sentences. Knight’s move thinking is a severe form of loosening of associations, characterized by unexpected and illogical leaps from one idea to another. Flight of ideas is a thought disorder that involves jumping from one topic to another, but with discernible links between them. Perseveration is the repetition of ideas or words despite attempts to change the topic. Finally, echolalia is the repetition of someone else’s speech, including the question that was asked.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 23 - An 81-year-old man is transferred from a nursing home with a change in...

    Correct

    • An 81-year-old man is transferred from a nursing home with a change in behaviour, insomnia and fever. Staff in the nursing home state that over the last five days, he has appeared confused and agitated and seems to be having visual hallucinations, as he has been talking and gesturing to people who are not present in the room. He has a past medical history of Lewy body dementia. On clinical examination, he is not orientated to time, place or person. He is mildly agitated. His blood pressure is 112/60 mmHg, pulse 96 bpm and temperature 38.2 °C. Urinalysis is positive for nitrites and leukocytes.
      Which of the following management plans should be considered as initial treatment for delirium?

      Your Answer: Treat the underlying cause, ensure effective communication and reorientation, provide reassurance for people diagnosed with delirium, provide a suitable care environment

      Explanation:

      Managing Delirium: Strategies for Treatment and Care Environment

      Delirium is a serious condition that requires prompt identification and management of underlying causes. Effective communication and reorientation, as well as reassurance for the patient, are crucial in managing delirium. Involving family, friends, and carers can also be helpful. Providing a suitable care environment, such as a well-lit and quiet room with minimal stimulation, is important. If verbal and non-verbal de-escalation techniques are ineffective, short-term use of antipsychotic drugs like haloperidol or olanzapine may be necessary, but caution should be exercised, especially for patients with conditions like Parkinson’s disease or dementia with Lewy bodies. Frequent reorientation and monitoring in a dimly lit room may also be necessary in some cases. Overall, a comprehensive approach that addresses both the underlying causes and the patient’s immediate needs is essential in managing delirium.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 24 - What is the mechanism of action of venlafaxine for elderly patients? ...

    Correct

    • What is the mechanism of action of venlafaxine for elderly patients?

      Your Answer: Serotonin and noradrenaline reuptake inhibitor

      Explanation:

      The mechanism of action of venlafaxine involves inhibiting the reuptake of both serotonin and noradrenaline, making it a type of antidepressant known as a serotonin and noradrenaline reuptake inhibitor. When choosing an antidepressant, factors such as patient preference, previous sensitization, overdose risk, and cost should be considered, although SSRIs are typically the first-line treatment due to their favorable risk-to-benefit ratio.

      Understanding Serotonin and Noradrenaline Reuptake Inhibitors

      Serotonin and noradrenaline reuptake inhibitors (SNRIs) are a type of antidepressant medication that work by increasing the levels of serotonin and noradrenaline in the brain. These neurotransmitters are responsible for regulating mood, emotions, and anxiety levels. By inhibiting the reuptake of these chemicals, SNRIs help to maintain higher levels of serotonin and noradrenaline in the synaptic cleft, which can lead to improved mood and reduced anxiety.

      Examples of SNRIs include venlafaxine and duloxetine, which are commonly used to treat major depressive disorders, generalised anxiety disorder, social anxiety disorder, panic disorder, and menopausal symptoms. These medications are relatively new and have been found to be effective in treating a range of mental health conditions. SNRIs are often preferred over other types of antidepressants because they have fewer side effects and are less likely to cause weight gain or sexual dysfunction.

      Overall, SNRIs are an important class of medication that can help to improve the lives of people struggling with mental health conditions. By increasing the levels of serotonin and noradrenaline in the brain, these medications can help to regulate mood and reduce anxiety, leading to a better quality of life for those who take them.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 25 - A 32-year-old woman presents to her GP for her 6-week postnatal check-up. She...

    Incorrect

    • A 32-year-old woman presents to her GP for her 6-week postnatal check-up. She mentions feeling mildly depressed at times but denies any issues with her eating or sleeping habits. She is managing well with taking care of her baby and has a strong support system from her loved ones. She is currently breastfeeding.
      What would be the most suitable course of action for her management?

      Your Answer: Refer her routinely to Psychiatry

      Correct Answer: Advise her about local social support: local children’s centres, mother and baby groups and the health visitor

      Explanation:

      For a patient experiencing mild postnatal depression symptoms, it is recommended to offer social support, non-directive counseling, or self-help strategies. Close follow-up is necessary, and if the condition worsens, other treatments may be necessary. Severe depression symptoms may include feelings of hopelessness or guilt, self-neglect, self-harm, or suicidal thoughts. The use of St John’s wort is not recommended for breastfeeding women due to safety concerns and potential interactions with other medications. Admission to a Mother and Baby Psychiatric Unit is reserved for patients with severe depression or psychosis who pose a high risk to themselves or others. Referral to psychiatry may be necessary if the patient’s condition changes. In mild cases, psychological and social interventions are preferred over pharmacological treatments such as SSRIs, which should only be considered in more severe cases and under the guidance of a specialist.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 26 - A 72-year-old man is admitted to the hospital by his wife who reports...

    Correct

    • A 72-year-old man is admitted to the hospital by his wife who reports that he has been experiencing distressing visual hallucinations of animals in their home. You suspect that he may be suffering from Charles-Bonnet syndrome. What are some potential risk factors that could make him more susceptible to this condition?

      Your Answer: Peripheral visual impairment

      Explanation:

      Peripheral visual impairment is a risk factor for Charles-Bonnet syndrome, which is a condition characterized by visual hallucinations in individuals with eye disease. The most frequent hallucinations include faces, children, and wild animals. This syndrome is more common in older individuals, without significant difference in occurrence between males and females, and no known increased risk associated with family history.

      Understanding Charles-Bonnet Syndrome

      Charles-Bonnet syndrome (CBS) is a condition characterized by complex hallucinations, usually visual or auditory, that occur in clear consciousness. These hallucinations persist or recur and are often experienced by individuals with visual impairment, although this is not a mandatory requirement for diagnosis. People with CBS maintain their insight and do not exhibit any other significant neuropsychiatric disturbance. The risk factors for CBS include advanced age, peripheral visual impairment, social isolation, sensory deprivation, and early cognitive impairment. The syndrome is equally distributed between sexes and does not show any familial predisposition. The most common ophthalmological conditions associated with CBS are age-related macular degeneration, glaucoma, and cataract.

      Well-formed complex visual hallucinations are experienced by 10-30% of individuals with severe visual impairment. The prevalence of CBS in visually impaired people is estimated to be between 11 and 15%. However, around a third of people with CBS find the hallucinations unpleasant or disturbing. A large study published in the British Journal of Ophthalmology found that 88% of people had CBS for two years or more, and only 25% experienced resolution at nine years. Therefore, CBS is not generally a transient experience.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 27 - A 47-year-old woman presents complaining of ‘flashbacks’. Seven months earlier, she had been...

    Correct

    • A 47-year-old woman presents complaining of ‘flashbacks’. Seven months earlier, she had been standing at a bus stop when a car swerved off the road into the queue, killing instantly a child standing near to her. Every day she experiences intrusive images of the child’s face as it saw the car mount the curb. She has not been able to go to that part of town since the day and she has avoided taking the bus anywhere. She feels she is always on edge and jumps at the slightest noise around the house. She thinks things are getting worse, rather than better, and asks you whether there are any psychological treatments that might help her.
      Which one of the following approaches is indicated?

      Your Answer: Trauma-focused cognitive behavioural therapy (CBT)

      Explanation:

      Treatment Options for Post-Traumatic Stress Disorder: Focus on Trauma-Focused CBT

      Post-traumatic stress disorder (PTSD) is a delayed and/or prolonged response to a traumatic event that can cause distress in almost anyone. Symptoms include intrusive flashbacks, avoidance of trauma-related triggers, emotional numbness, and hypervigilance. Trauma-focused cognitive behavioural therapy (CBT) is the recommended first-line treatment for PTSD, according to the National Institute for Health and Care Excellence (NICE) in the United Kingdom. Other therapies, such as psychodynamic therapy, supportive therapy, and hypnotherapy, may be helpful but are not first-line approaches. Watchful waiting is only appropriate for mild symptoms present for less than a month. It is important to seek help for PTSD, and trauma-focused CBT is a proven effective treatment option.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 28 - A 20-year-old woman presents to her General Practitioner (GP) with a 2-year history...

    Correct

    • A 20-year-old woman presents to her General Practitioner (GP) with a 2-year history of restricting food intake and self-induced vomiting. She attends her GP for the first time with her sibling reporting a recent worsening of her symptoms. The GP suspects anorexia nervosa.
      Which is the most appropriate investigation to determine whether the patient requires urgent hospital admission?

      Your Answer: Electrocardiogram (ECG)

      Explanation:

      Medical Investigations for Anorexia Nervosa: What to Expect

      Anorexia nervosa is a serious eating disorder that can have significant impacts on a person’s physical health, including their cardiovascular system. When assessing a patient with anorexia nervosa, there are several medical investigations that may be considered. Here is what you can expect:

      Electrocardiogram (ECG): This is a baseline test that assesses heart rate and the QT interval. Electrolyte imbalances caused by eating disorders can affect cardiac stability, so it’s important to check for any cardiovascular instability.

      24-hour Holter monitor: This test may be considered if there is a problem with the baseline ECG or a history of cardiac symptoms such as palpitations.

      Chest X-ray: This is not routinely required unless there are other respiratory symptoms present.

      Serum prolactin: This test is not routinely required unless there is a history of galactorrhoea or amenorrhoea.

      Transthoracic echocardiography: This test is not routinely required unless there are clinical indications for imaging of the heart.

      Overall, medical investigations for anorexia nervosa are tailored to the individual patient’s needs and medical history. It’s important to work closely with a healthcare provider to determine which tests are necessary for each patient.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 29 - A 30-year-old woman is brought to the Emergency Department after attempting to end...

    Correct

    • A 30-year-old woman is brought to the Emergency Department after attempting to end her life by jumping from a height. On examination, she is conscious and has significant bruising over the occiput region. She reports that her parents are recently divorced and it has caused significant strain on her current relationship and as a result, is failing to do well at work. She has no significant medical history, apart from an incident when she was 17 where she was admitted to the hospital after intentionally taking too many paracetamol.
      Which of the following from the patient’s history is most associated with an increased risk of repeated attempts of self-harm/suicide?

      Your Answer: Previous attempted suicide

      Explanation:

      Risk Factors for Repeated Self-Harm and Suicide Attempts

      Previous suicide attempts or episodes of self-harm are the biggest predictor of future attempts, with 15% of people attempting again within a year and 1% succeeding in committing suicide. Strained relationships with partners or dissatisfaction with work alone have not been linked to repeated attempts. However, significant life events such as parental divorce, bereavement, abuse, or family breakdown may increase the risk. Age alone, particularly for adults in their twenties, has not been associated with repeated self-harm or suicide attempts.

    • This question is part of the following fields:

      • Psychiatry
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  • Question 30 - A 28-year-old patient presents to her doctor with symptoms of low mood and...

    Incorrect

    • A 28-year-old patient presents to her doctor with symptoms of low mood and anhedonia. She has previously undergone cognitive behavioural therapy and art therapy, but with limited success. The doctor prescribes citalopram and refers her for additional talk therapy.
      What medication should be avoided while taking citalopram?

      Your Answer: Nitrofurantoin

      Correct Answer: Rasagiline

      Explanation:

      Combining SSRIs and MAOIs is not recommended due to the potential danger of developing serotonin syndrome.

      Selective serotonin reuptake inhibitors (SSRIs) are commonly used as the first-line treatment for depression. Citalopram and fluoxetine are the preferred SSRIs, while sertraline is recommended for patients who have had a myocardial infarction. However, caution should be exercised when prescribing SSRIs to children and adolescents. Gastrointestinal symptoms are the most common side-effect, and patients taking SSRIs are at an increased risk of gastrointestinal bleeding. Patients should also be aware of the possibility of increased anxiety and agitation after starting a SSRI. Fluoxetine and paroxetine have a higher propensity for drug interactions.

      The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a warning regarding the use of citalopram due to its association with dose-dependent QT interval prolongation. As a result, citalopram and escitalopram should not be used in patients with congenital long QT syndrome, known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval. The maximum daily dose of citalopram is now 40 mg for adults, 20 mg for patients older than 65 years, and 20 mg for those with hepatic impairment.

      When initiating antidepressant therapy, patients should be reviewed by a doctor after 2 weeks. Patients under the age of 25 years or at an increased risk of suicide should be reviewed after 1 week. If a patient responds well to antidepressant therapy, they should continue treatment for at least 6 months after remission to reduce the risk of relapse. When stopping a SSRI, the dose should be gradually reduced over a 4 week period, except for fluoxetine. Paroxetine has a higher incidence of discontinuation symptoms, including mood changes, restlessness, difficulty sleeping, unsteadiness, sweating, gastrointestinal symptoms, and paraesthesia.

      When considering the use of SSRIs during pregnancy, the benefits and risks should be weighed. Use during the first trimester may increase the risk of congenital heart defects, while use during the third trimester can result in persistent pulmonary hypertension of the newborn. Paroxetine has an increased risk of congenital malformations, particularly in the first trimester.

    • This question is part of the following fields:

      • Psychiatry
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SESSION STATS - PERFORMANCE PER SPECIALTY

Psychiatry (20/30) 67%
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