00
Correct
00
Incorrect
00 : 00 : 0 00
Session Time
00 : 00
Average Question Time ( Secs)
Retry this test Dashboard

  • Question 1 - What is the mode of inheritance of beta Thalassemia? ...

    Correct

    • What is the mode of inheritance of beta Thalassemia?

      Your Answer: Autosomal recessive

      Explanation:

      Beta Thalassaemia is autosomal recessive.

    • This question is part of the following fields:

      • Genetics
      3.8
      Seconds

  • Question 2 - Which of the following is the leading cause of Down Syndrome? ...

    Correct

    • Which of the following is the leading cause of Down Syndrome?

      Your Answer: Nondisjunction maternal gamete

      Explanation:

      Most of the cases of down syndrome occur due to non disjunction trisomy 21 which is associated with increased maternal age. The non disjunction occurs in the maternal gametes.

    • This question is part of the following fields:

      • Genetics
      3
      Seconds

  • Question 3 - All are true about monozygotic pregnancy, EXCEPT: ...

    Correct

    • All are true about monozygotic pregnancy, EXCEPT:

      Your Answer: The 1st commonly presents as breech

      Explanation:

      The 1st commonly presents as cephalic. Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical.

    • This question is part of the following fields:

      • Genetics
      28.5
      Seconds

  • Question 4 - A women has undergone genetic testing due to her family history and has...

    Correct

    • A women has undergone genetic testing due to her family history and has the BRCA 2 gene. What would you advise her lifetime risk of breast cancer is?

      Your Answer: 45%

      Explanation:

      The life time risk of breast cancer in BRCA 2 gene is 45% and of ovarian cancer is 15%.

    • This question is part of the following fields:

      • Genetics
      6
      Seconds

  • Question 5 - A pregnant patient who is needle phobic has her nuchal translucency (NT) scan...

    Incorrect

    • A pregnant patient who is needle phobic has her nuchal translucency (NT) scan but refuses serum markers. You advise her the False Positive Rate of the scan is 5%. What would you advise the mother regarding the detection rate of Down Syndrome using NT alone?

      Your Answer: 95%

      Correct Answer: 70%

      Explanation:

      The nuchal lucency measurement is the measure of the nuchal pad thickness. Children with down syndrome have an increased thickness of the nuchal pad. The risk of down’s syndrome increases with maternal age. The nuchal lucency test has an accuracy rate of 70%.

    • This question is part of the following fields:

      • Genetics
      9.8
      Seconds

  • Question 6 - Regarding monozygotic twins, all of the following are correct, EXCEPT: ...

    Incorrect

    • Regarding monozygotic twins, all of the following are correct, EXCEPT:

      Your Answer: Has a constant incidence of 1:250 births

      Correct Answer: Has a constant incidence 1:600 births

      Explanation:

      The incidence of monozygotic twins is constant worldwide (approximately 4 per 1000 births). Approximately two thirds of twins are dizygotic.

    • This question is part of the following fields:

      • Genetics
      20.7
      Seconds

  • Question 7 - Which of the following statements regarding BRCA gene mutations is true? ...

    Incorrect

    • Which of the following statements regarding BRCA gene mutations is true?

      Your Answer: None of the above statements are true

      Correct Answer: They account for around 25% of inherited breast cancers

      Explanation:

      Hereditary breast cancers account for 10 % of the cases. BRCA gene mutations account for 25 % of these cancers.

    • This question is part of the following fields:

      • Genetics
      24.1
      Seconds

  • Question 8 - A 40 year old women who is 13 weeks pregnant is found to...

    Correct

    • A 40 year old women who is 13 weeks pregnant is found to have be high risk for Downs following the combined screening test. What is the most appropriate further test to see if the foetus is affected?

      Your Answer: Chorionic Villous Sampling

      Explanation:

      Chorion villus sampling is an invasive procedure which aims to collect the rapidly dividing cells in the placenta. It is used for numerous reasons including detection of early pregnancy, viability of the foetus, singleton pregnancy, confirm gestation age and for prenatal diagnosis of the fetal chromosomal abnormalities including diagnosis of Down’s syndrome. However it hold a 2% chance of miscarriage during the procedure. Nuchal thickness and imaging are part of the combined test that must have been performed before.

    • This question is part of the following fields:

      • Genetics
      10.6
      Seconds

  • Question 9 - Regarding twin pregnancies all of the following are correct EXCEPT: ...

    Correct

    • Regarding twin pregnancies all of the following are correct EXCEPT:

      Your Answer: Identical or monozygotic twins arise from fertilization of two ovum

      Explanation:

      Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical.

    • This question is part of the following fields:

      • Genetics
      24.4
      Seconds

  • Question 10 - Regarding Turner syndrome which of the following statements is true? ...

    Correct

    • Regarding Turner syndrome which of the following statements is true?

      Your Answer: Only 1% of affected foetuses will survive to term

      Explanation:

      The incidence of 45,XO turner syndrome is around 1 in 8000 live births. Approximately 1% of monosomy X female embryos survive. Phenotypically they are females and 90% do not develop secondary sexual characteristics and hormone replacement is required.

    • This question is part of the following fields:

      • Genetics
      15.1
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Genetics (7/10) 70%
Passmed
Retry this test Dashboard