MSFinals-5140
A 25-year-old woman who injects heroin intravenously presents for evaluation. What is the most probable complication that will arise from her drug use?
A 25-year-old woman who injects heroin intravenously presents for evaluation. What is the most probable complication that will arise from her drug use?
A 25-year-old male arrives at the Emergency Department following a paracetamol overdose. He reports taking 40 tablets in the last 3 hours and has presented to the hospital within 10 minutes of ingesting the last tablet. He weighs 70kg. What is the best course of action to take next?
A new medication, Vilastem, has been developed to improve nausea in elderly patients with terminal cancer. It has recently gained marketing approval but a new side effect is identified via the yellow card scheme.
What phase of drug development does this represent?
As an investigator, you will be participating in a clinical trial of a new antihypertensive agent. The drug has already been tested on healthy volunteers, but this trial will be the first to involve patients. The aim of the trial is to determine the optimal dosage for therapy, which will be used in future studies. Are you ready to take part in this clinical trial?
A new drug, RUB98475622, is being tested in animal studies to improve sleep disturbance in individuals with obstructive sleep apnoea. At what stage of drug development is this currently?
A new medication, Horriblex, has been developed to improve pain in elderly patients with rheumatoid arthritis (RA). A study is being conducted to evaluate the pharmacodynamics and dose effects of the medication in elderly patients with RA.
What phase of drug development does this study represent?
A clinical trial is currently underway to evaluate the effectiveness of Smellexat, a new medication for mild-moderate hayfever symptoms, compared to standard therapy with cetirizine. At what stage of drug development is this trial?
A senior citizen has been prescribed an antidepressant by a hospital specialist. During the consultation, she was cautioned against consuming cheese and game.
Which of the following antidepressants is she most likely taking?
Each of the following drugs are known to induce cytochrome p450 enzyme, except which one?
Rifampicin
12%
Isoniazid
47%
Phenobarbitone
8%
Griseofulvin
23%
Carbamazepine
10%
Is it true that isoniazid inhibits the P450 system? This information is important for me to know.
Which of the options listed does not have a decreasing effect on bronchial secretions?