MSFinals-4067

At what age should the oral rotavirus vaccine be administered as part of the NHS immunisation schedule?

MSFinals-4068

The mother of a 3-year-old child is worried about her child’s developmental progress. Upon assessment, you observe that the child can only build a tower of five blocks at most and can only speak in two to three-word phrases. What is the typical age range for a healthy child to achieve these developmental milestones?

MSFinals-4069

A 4-year-old boy visits his GP for his routine vaccinations. He has received all the recommended vaccines for his age group and has not experienced any adverse reactions. He is in good health and his height and weight are within normal range. The child’s family migrated from India six years ago. What vaccinations should the doctor administer during this visit?

MSFinals-4070

A 1-year-old child is brought to the emergency room with poor muscle tone, gasping respirations, cyanosis, and a heart rate of 80 bpm. The child’s APGAR score is 3 and is placed in the sniffing position for airway maintenance. However, there are no changes noted on reassessment. After positive pressure ventilation for 30 seconds, the child is now showing shallow respirations and a heart rate of 50 bpm. Chest compressions are initiated. What is the recommended compression: ventilation ratio for this child?

MSFinals-4071

A 6-year-old girl is brought to her general practitioner by her mother because she is shorter than most of her classmates. She gets good grades and does well in school. She is below the fifth percentile for height for her age. On examination, she is short and has a webbed neck and widely spaced nipples.
Which one of the following is karyotyping most likely to reveal?

MSFinals-4072

A 5-year-old girl visits her pediatrician with a fever, red tongue, and a rash that started on her torso and has now spread to the soles of her feet. The rash has a rough texture like sandpaper. The doctor prescribes oral antibiotics for ten days. The girl’s mother is worried about her daughter’s absence from school and asks when she can return.
What is the appropriate time for the girl to go back to school?

MSFinals-4073

What is the most common age for the presentation of hereditary multiple exostosis (osteochondroma)?

MSFinals-4074

A 35-year-old man has been experiencing muscle weakness and cramps, and after extensive investigation, it has been determined that he has a rare form of myopathy. His family history reveals that his mother, maternal grandmother, brother, maternal aunt, and her two sons are all affected by the same condition. Interestingly, his maternal uncle has the disease, but none of his children do. There is no evidence of the disease on the paternal side, and his wife has no family history of the disorder. What is the likelihood that his biological children will inherit the myopathy from him?

MSFinals-4075

A 41-year-old female with a history of Leber’s optic atrophy visits her doctor. She and her husband are planning to have children and she wants to know the likelihood of passing on her condition. She vaguely remembers her geneticist mentioning something about mitochondria but can’t recall the specifics of the inheritance pattern. Assuming her husband does not carry the same gene defect, what is the chance that their child will inherit the condition?

MSFinals-4076

A couple, one male and one female, seek genetic counselling as a family member has been diagnosed with sickle cell anaemia, an autosomal recessive condition. After testing, it is discovered that both individuals are carriers of sickle cell anaemia. The woman is currently 16 weeks pregnant.

What is the likelihood that their unborn child will also be a carrier of sickle cell anaemia?