MSFinals-2826

A fifty-six-year-old man visits his GP with complaints of recurring headaches and limb pain that have persisted for six months. Despite taking ibuprofen and paracetamol, he has not experienced any relief. The headaches occur without any preceding symptoms, last for less than an hour, and do not cause dizziness or nausea. They occur 4-6 times per day. Additionally, he has noticed a loss of hearing in his left ear. The GP conducts some blood tests, which reveal elevated alkaline phosphatase (ALP), normal calcium, normal phosphate, and normal thyroid hormone levels. Based on the most probable diagnosis, what is the most appropriate treatment?

MSFinals-2827

Samantha is a 62-year-old woman who visits her GP complaining of painless swelling of lymph nodes in her left armpit. Upon further inquiry, she admits to experiencing night sweats and losing some weight. Samantha has a history of Sjogrens syndrome and is currently taking hydroxychloroquine. During the examination, a 3 cm rubbery lump is palpable in her left axilla, but no other lumps are detectable. Her vital signs are within normal limits. What is the most probable diagnosis?

MSFinals-2828

The existence of anti-cyclic citrullinated peptide antibody indicates which of the following conditions?

MSFinals-2829

What type of hypersensitivity is defined in idiopathic thrombocytopenic purpura (ITP), a condition marked by autoimmune platelet destruction?

MSFinals-2830

What category of hypersensitivity is characterized by immune system dysregulation in systemic lupus erythematosus (SLE), an inflammatory disorder affecting multiple systems?

MSFinals-2831

A 13-year-old boy experiences facial swelling and a red, itchy rash shortly after receiving his first dose of the HPV vaccine. Upon arrival, paramedics observe a bilateral expiratory wheeze and a blood pressure reading of 85/60 mmHg. According to the Gell and Coombs classification of hypersensitivity reactions, what type of reaction is this an example of?

MSFinals-2832

A young child develops an eczematous, weeping rash on their wrist after receiving a new bracelet. In the Gell and Coombs classification of hypersensitivity reactions, what type of reaction is this an example of?

MSFinals-2833

A 32-year-old man presents to clinic for review. His recent echocardiogram showed no changes in the dilation of his aortic sinuses or mitral valve prolapse. Upon examination, he is tall with pectus excavatum and arachnodactyly. Which protein defect is primarily responsible for his condition?

MSFinals-2802

A 65-year-old woman visits her GP complaining of a persistent headache that has been bothering her for two weeks. The pain is more intense on the right side and is aggravated when she combs her hair. She also experiences discomfort in her jaw when eating. Her neurological and fundoscopy examinations reveal no abnormalities, and she is referred to the emergency department.

Upon admission, the patient is prescribed high-dose oral prednisolone and undergoes a temporal artery biopsy, which yields normal results. What is the next most appropriate course of action for her treatment?

MSFinals-2803

A 42-year-old swimmer complains of left shoulder pain that has been progressively worsening for the past 2 months. The pain is most noticeable during front or back crawl strokes, but she can still perform breaststroke without discomfort. She is unable to lie on her left side. During the examination, you observe pain when the shoulder is abducted between 90-120 degrees, but there is no tenderness upon palpation. There is no noticeable weakness in the rotator cuff muscles when compared to the other arm. What is the most probable diagnosis?