MSFinals-2418

A 54-year-old woman presents to the rheumatology clinic with severe Raynaud’s phenomenon and finger arthralgia. Upon examination, you observe tight and shiny skin on her fingers, as well as several telangiectasia on her upper torso and face. She is also awaiting a gastroscopy for heartburn investigation. Which antibody is the most specific for the underlying condition?

MSFinals-2419

Which of the following antibodies is the most specific for limited cutaneous systemic sclerosis?

MSFinals-2420

An 83-year-old woman visits her GP complaining of generalised weakness that has been ongoing for a month. She mentions having difficulty standing up after sitting down. She also reports noticing a red rash on her chest, but denies any itching. Her medical history is unremarkable except for hypertension that is well-controlled.

During the physical examination, the doctor observes dry hands with linear cracks and violaceous papules on both knuckles. The patient also has a distinct purple rash around each eyelid. What is the most specific antibody for the probable diagnosis?

MSFinals-2421

An 80-year-old female visits her GP complaining of muscle weakness that has been gradually worsening for the past year. She is unable to stand or walk for extended periods of time. Additionally, she has a purple rash on her eyelids, red nodules on her knees and elbows, and painful cracked skin on her fingers. Which autoantibody is the probable cause of these symptoms?

MSFinals-2422

Mrs. Jane is a 55-year-old woman who visits her GP with a complaint of frank haematuria that has been present for a week. She also reports a persistent dry cough and dyspnoea that has been bothering her for the past 3 months, along with a long-standing history of sinusitis and nosebleeds. During the examination, the patient is found to have a saddle-shaped nasal deformity and bilateral crepitations on auscultation. What is the specific antibody that is most closely associated with this patient’s condition?

MSFinals-2423

A 35-year-old female patient arrives with an abrupt onset of hemiparesis on the right side, affecting the face, arm, and leg. During the examination, you observe right-sided hemiparesis, aphasia, and a right homonymous hemianopia. The patient has a medical history of recurrent miscarriages, pulmonary embolisms, and deep vein thrombosis. The blood test results show a prolonged APTT. What could be the probable reason for the stroke?

MSFinals-2424

During a routine examination for private medical insurance, a 30-year-old female with a history of Ehler-Danlos syndrome presents with widespread bruising and a faint diastolic murmur on chest auscultation. What is the most likely complication of Ehler-Danlos that she is experiencing?

MSFinals-2425

A 65-year-old man experiences bilateral calf pain that forces him to stop walking after 100 yards. He discovers that walking uphill and bending forward alleviates the pain. However, he can ride a bike without any discomfort. What is the probable root cause of his condition?

MSFinals-2426

A 50-year-old woman has arrived at the emergency department via ambulance after twisting her left ankle while hiking in a mountainous national park. She has no significant medical history. X-rays were taken and the radiologist’s report states that there is a minimally displaced, transverse fracture distally through the lateral malleolus, below the level of the talar dome, without talar shift. The medial malleolus is unaffected. What is the most suitable immediate management?