MSFinals-2042
What is the blood product that poses the greatest risk of bacterial infection transmission during transfusion?
Archives: Medical Student Finals
MSFinals-2008
Who among the following prospective blood donors would be ineligible to donate whole blood or plasma?
MSFinals-2009
A 5-year-old girl presents with purpura following a recent upper respiratory infection. Upon examination, her platelet count is found to be 20 ×109/L (normal range: 150-400) and a bone marrow examination reveals megakaryocyte hyperplasia. What is the correct statement regarding her condition?
MSFinals-2010
A 68-year-old woman presents with lethargy and poor exercise tolerance. She also mentions that, over the last month, she has had excessive thirst and polyuria.
Initial investigations show:
Investigation Result Normal value
Haemoglobin (Hb) 78 g/l 115–155 g/l
Erythrocyte sedimentation rate (ESR) 109 mm/h 0–10mm in the first hour
Sodium (Na+) 134 mmol/l 135–145 mmol/l
Potassium (K+) 5.8 mmol/l 3.5–5.0 mmol/l
Urea 26.5 mmol/l 2.5–6.5 mmol/l
Creatinine 268 µmol/l 50–120 μmol/l
Corrected calcium (Ca2+) 3.02 mmol/l 2.20–2.60 mmol/l
Glucose 5.2 mmol/l 3.5–5.5 mmol/l
Which of the following tests is the most appropriate to confirm the underlying diagnosis?
MSFinals-2011
A 65-year-old woman is two days postoperative, following a Hartmann’s procedure for bowel cancer. Her haemoglobin levels had dropped to 70 g/l, and as a result, she was started on a blood transfusion 12 hours ago. You are asked to review the patient, as she has suddenly become very agitated, pyrexial and hypotensive, with chest pain.
Which of the following transfusion reactions is most likely to be occurring in this patient?
MSFinals-2012
A patient on a medical ward received a transfusion 72 hours ago for symptomatic anaemia on a background of chronic renal disease and obstructive airways disease. He has a history of previous transfusions in the last six months. The patient, who is in his 60s, has now dropped his Hb by 20 g/L compared to his pretransfusion level and reports a dark coloured urine. The LDH and bilirubin are elevated. What is the most likely explanation for these findings?
MSFinals-2013
A 36-year-old Afro-Caribbean woman presents to the Emergency Department complaining of shortness of breath, fever and a productive cough. She has suffered multiple severe infections over the past five years; however, she has no other past medical history.
On examination, you note intercostal recessions and the use of accessory muscles of respiration. She has significant coarse crepitations in her right lower lobe.
You take some basic observations, which are as follows:
Temperature: 39.8 °C
Heart rate: 120 bpm
Respiratory rate: 26 breaths/min
Blood pressure: 150/94 mmHg (lying) 146/90 mmHg (standing)
Oxygen saturation: 86% on room air
Her initial investigation findings are as follows:
Investigation Result Normal value
White cell count (WCC) 14.4 × 109/l 4–11. × 109/l
Neutrophils 12800 × 106/l 3000–5800 × 106/l
Lymphocytes 1400 × 106/l 1500–3000 × 106/l
Haemoglobin (Hb) 110 g/dl 115–155 g/dl
Mean corpuscular volume (MCV) 94 fl 76–98 fl
Platelets 360 × 109/l 150–400 × 109/l
Her chest X-ray shows significant consolidation in the right lower lobe.
A blood film comes back and shows the following: sickled erythrocytes and Howell–Jolly bodies.
A sputum culture is grown and shows Streptococcus pneumoniae, and the patient’s pneumonia is managed successfully with antibiotics and IV fluid therapy.
What condition is predisposing this patient to severe infections?
MSFinals-2014
A 35-year-old woman with type 1 diabetes and Addison’s disease presents with a two-month history of increasing fatigue and shortness of breath during physical activity. She is currently using a progesterone-only oral contraceptive and taking hydrocortisone 10 mg twice daily and fludrocortisone 100 µg per day. Her glycaemic control has been reasonable, with a last HbA1c of 65 mmol/mol (20-46), and she is receiving mixed insulin twice daily. On examination, she appears pale. A full blood count reveals the following results: haemoglobin 52 g/L (120-160), MCV 115 fL (80-96), WCC 4.2 ×109/L (4-11), platelets 126 ×109L (150-400), and MCH 32 pg (28-32). The blood film shows multilobed nuclei in neutrophils and macrophages. What is the probable cause of her symptoms?
MSFinals-2015
A 28-year-old woman who is 30 weeks pregnant arrives at the emergency assessment unit with concerns of fluid leakage from her vagina. Upon examination, her pad is saturated with what appears to be amniotic fluid. What component of the fluid may indicate premature rupture of membranes (PROM)?
MSFinals-2016
A 35-year-old woman comes to the clinic for follow-up three months after undergoing evacuation of a hydatidiform mole. She reports feeling well and has not experienced any significant issues since the procedure.
What blood test is the most effective in monitoring for the recurrence of trophoblastic disease?